• The KIPS Transactions:PartB
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• v.14B no.1 s.111
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• pp.51-58
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• 2007

This paper suggests prototype of dialog system combining VXML(VoiceXML) that is the W3C's standard XML format for specifying interactive voice dialogues between human and computer, and RSS(RDF Site Summary or Really Simple Syndication) that is representative technology of semantic web for syndication and subscription of updated web-contents. Merits of the proposed system are as following: 1) It is a new method that recognize spoken contents using ire and wireless telephone networks and then provide contents to user via STT(Speech-to-Text) and TTS(Text-to-Speech) instead of traditional method using web only. 2) It can apply advantage of RSS that subscription of updated contents is converted to VXML without modifying traditional method to provide RSS service, 3) In terms of users, it can reduce restriction on time-spate in search of contents that is provided by RSS because it uses ire and wireless telephone networks, not internet environment. 4) In terms of information provider, it does not need special component for syndication of the newest contents using speech recognition and synthesis technology. We implemented a news service system using VXML and RSS for performance evaluation of the proposed system. In experiment results, we estimated the response time and the speech recognition rate in subscription and search of actuality contents, and confirmed that the proposed system can provide contents those are provided using RSS Feed.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.42 no.1
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• pp.39-45
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• 2005

As a basic research for the development of a non-invasive blood glucose sensor using millimeter waves, we have presented a method for measuring the dielectric properties of high loss dielectrics, based on the reflection method, and investigated the variation of the dielectric properties of glucose-water and glucose -0.9% NaCl solutions in the 10～90 GHz range. In the proposed method, a minimal reflection condition is formed by placing a specially-chosen low-loss plane-parallel plate in front of a high-loss medium under test at a given frequency range. Using the minimal power reflection coefficient and the corresponding frequency at this condition, tile dielectric properties of the medium can be determined. The measured results on pure water have shown the adequacy of the proposed method. The measured results on glucose-water and glucose -0.9% NaCl solutions in the 10～90 GHz range showed that the variations of the dielectric properties of glucose solutions according to the change of their glucose concentration were maximum in the 30～45 GHz range. From these facts we concluded that the variation of about 3 mole/L in the glucose solutions must be distinguished With the measurement accuracies of ±0.1 dB and ±0.01 GHz.

• Clinical and Experimental Reproductive Medicine
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• v.42 no.1
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• pp.1-7
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• 2015

Stress coping mechanisms are critical to minimize or overcome damage caused by ever changing environmental conditions. They are designed to promote cell survival. The unfolded protein response (UPR) pathway is mobilized in response to the accumulation of unfolded proteins, ultimately in order to regain endoplasmic reticulum (ER) homeostasis. Various elements of coping responses to ER stress including Perk, Ask1, Bip, Chop, Gadd34, Ire1, Atf4, Atf6, and Xbp1 have been identified and were found to be inducible in oocytes and preimplantation embryos, suggesting that, as a normal part of the cellular adaptive mechanism, these coping responses, including the UPR, play a pivotal role in the development of preimplantation embryos. As such, the UPR-associated molecules and pathways may become useful markers for the potential diagnosis of stress conditions for preimplantation embryos. After implantation, ER stress-induced coping responses become physiologically important for a normal decidual response, placentation, and early organogenesis. Attenuation of ER stress coping responses by tauroursodeoxycholate and salubrinal was effective for prevention of cell death of cultured embryos. Further elucidation of new and relevant ER stress coping responses in periimplantation embryos might contribute to a comprehensive understanding of the regulation of normal development of embryonic development and potentiation of embryonic development in vitro.

• Biomedical Science Letters
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• v.12 no.4
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• pp.435-438
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• 2006

In eukaryotes, ER stress induces UPR (unfolded protein response) via IRE1 activation which sends a molecular signal for XBP1 mRNA splicing in the cytosol. During this mRNA splicing, 23 nt removed in which contains PstI site and then resulting XBP1 product is not digested with PstI restriction enzyme. In this study, using this XBP1 mRNA splicing mechanism, the effect of heat shock on thyrocytes is studied, because heat shock response in the thyrocytes needs more study to understand thyroid physiology under alternative environments. ER inducible drugs (tunicamycin, DTT, $Ca^{2+}$ ionopore A23187, BFA) induce ER stress in the thyrocytes. From 3 hours after heat shock, ER stress is induced and which is reversible when heat shock is without. While $Ca^{2+}$ ionopore A23187 is reversible from ER stress by washing out the drug, thapsigagin is irreversible. Other ER inducible drugs are not so sensitive to ER stress repairing. XBP1 mRNA splicing in a cell is very available method to detect ER stress. It needs only a small quantity of total RNA and processing also very easy.

• Molecules and Cells
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• v.41 no.11
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• pp.964-970
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• 2018

Atherosclerosis preferentially involves in prone area of low and disturbed blood flow while steady and high levels of laminar blood flow are relatively protected from atherosclerosis. Disturbed flow induces endoplasmic reticulum (ER) stress and the unfolded protein response (UPR). ER stress is caused under stress that disturbs the processing and folding of proteins resulting in the accumulation of misfolded proteins in the ER and activation of the UPR. Prolonged or severe UPR leads to activate apoptotic signaling. Recent studies have indicated that disturbed flow significantly up-regulated $p-ATF6{\alpha}$, $p-IRE1{\alpha}$, and its target spliced XBP-1. However, the role of laminar flow in ER stress-mediated endothelial apoptosis has not been reported yet. The present study thus investigated the role of laminar flow in ER stress-dependent endothelial cell death. The results demonstrated that laminar flow protects ER stress-induced cleavage forms of PARP-1 and caspase-3. Also, laminar flow inhibits ER stress-induced $p-eIF2{\alpha}$, ATF4, CHOP, spliced XBP-1, ATF6 and JNK pathway; these effects are abrogated by pharmacological inhibition of PI3K with wortmannin. Finally, nitric oxide affects thapsigargin-induced cell death in response to laminar flow but not UPR. Taken together, these findings indicate that laminar flow inhibits UPR and ER stress-induced endothelial cell death via PI3K/Akt pathway.

• The Korean Journal of Food And Nutrition
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• v.5 no.1
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• pp.33-40
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• 1992

This research was attempted to investigate the sex bias in nutrition knowledge, food preference and food roles in the family. 152 couples living in Seoul, Cheonan in the 205∼605 were selected for this research as subjects from October 1 to December 20, 1991. The data analysis was made by way of ire quency, percentage, X2-test using SPSS package. The summarized results are as follows. 1. The survey on the sex bias in nutrition knowledge related heart disease on the subjects showed that there were no significant differences between men and women. But women had a relatively good nutrition knowledge than men. Especially women had a good nutrition knowledge that low sodium diet and exercise are efficient on preventing heart disease. 2. On the food preference, the subject showed significant difference between men and women. Men showed a relatively highest preference for protein food just as pork, fish, and tofu. Women showed a relatively highest preference for bread, fruit and vegetable. 3. On the food roles, the subjects showed that gender difference in household labor regarding food preparation still exit. Food-related activities are clearly still the domain of women in most families. Husbands and wives in younger families tended to think the husbands showed increase their efforts in food related activities.

• Resources Recycling
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• v.8 no.4
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• pp.30-38
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• 1999

High 1emperiltur.e propeitles o i cold bonded pellet based on lroll beanng dusts wele invesligaled prim to using as a burden m blasl furnaces, Major conclusions ould be summarized Io llows: the cold bonded pellet needed to bc produced by the characteristic criterion on high lempemhIre prapcrttes as well as a compressive sncnglh. Basicity of cold bonded pellel shruld be linted to be appoxiiniltely 1.7 in order to maintain appropriate softcn~nga nd rnelt~ngp ropcrlies. On thc other hand. basiciq greater than 2.6 showed exce\ulcornersive puessure drop due to powder gelleratlon. Potcntialil], of blast fi~rnaccs lag as binding malerial in m a h g cold ba~~deprel llels !\.us also certified in viewpoinls of high temperature properly.

• Proceedings of the Korean Institute of Industrial Safety Conference
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• 1997.11a
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• pp.43-48
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• 1997

The smoke filling process for the atrium space containing a fire source is simulated using two types of deterministic fire modus: Zone model and Field model. The zone mode used is the CFAST(version 1.6) mode developed at the Building and Fire Research laboratories, NIST in the USA. The lied model is a self-developed fire field model based on Computational Fluid Dynamics(CFD) theories. This article is focused on finding out the smoke movement and temperature distribution in atrium space which is cubic in shape. A computational procedure for predicting velocity and temperature distribution in fro-induced flow is based on the solution, in finite volume method and non-staggered grid system, of 3-dimensional equations for the conservation of mass, momentum, energy, species and so forth. The fire model i. e. Zone model and Field model predicted similar results for Ire clear height and the smoke layer temperature.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.17 no.1
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• pp.103-111
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• 2003

With the proliferation of nonlinear loads such as personal computer in an educational building, high neutral harmonic currents have been observed. High neutral currents in three-phase four ire distribution power systems can cause tots of harmonic problems such as overloaded neutral conductors and malfunction of protective equipment. On-site measurements of harmonic currents and voltages were made and the corresponding equivalent circuits was developed. The circuit model under study was simulated numerically and graphically through the use of the software MATLAB. Simulation results verifying the effect of a single-tuned passive filter for the neutral harmonic current reduction are presented.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.8
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• pp.1-7
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• 2007

Class AB bipolar linear transconductors for high frequency applications ire proposed. They consist of a voltage follower, a resistor, and a current follower. The follower circuits are realized by translinear cells or unity-gain buffers. The proposed transconductors are simulated using an 8 GHz bipolar transistor-arrary parameter. Simulation results show that the transconductor using translinear cells has better linearity than one using unity-gain buffers whereas the latter has better temperature stability and higher input resistance than the former. In order to test their high frequency applicability, the transconductors are used to implement an 4th order IF bandpass filter.