• Toxicological Research
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• v.13 no.1_2
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• pp.61-69
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• 1997

Exposure of splenocytes to 2-chloroethylethyl sulfide (CEES) resulted in the cell death, and the cytotoxicity of CEES was prevented by inhibitors of lysosomal hydrolases. Therefore, it has been postulated that the cytotoxicity of CEES may be partially due to the lysosomal labilization. This study, based on this mechanism, was undertaken to determine whether aminoglycoside antibiotics as inhibitors of lysosomal phospholipases and their combinations with other lysosome stabilizers can be useful as a treatment to reduce the CEES toxicity in mice. 2-Chloroethylethyl sulfide (20 mg/kg body weight) was injected ip into female ICR mice, and candidate compounds were administered ip before or after the CEES challenge. Kanamycin (40 mg/kg body weight) as effective as deferoxamine (100 mg/kg body weight) enhanced the survival rate after 5 days of intoxication from 10% of control to 50 - 60%. The most effective was found to be the combination of kanamycin, cycloheximide, deferoxamine and dextrose showing an almost full protection against 2LD50 of CEES. Consistent with the protection of the CEES toxicity, the decrease of body weight in mice intoxicated with CEES was effectively prevented by kanamycin or its combinations. It is suggested that kanamycin or its combination (kanamycin, cycloheximide, deferoxamine and dextrose) would be one of effective antidotes against the CEES poisoning in mice.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.45 no.6
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• pp.74-79
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• 2008

In this paper, we propose and design a new 0.264/AVC watermarking algorithm for protection of copyright by inserting a watermark after quantization. This invisible watermarking algorithm insets a watermark into chrominance components of I frame such that we can avoid degradation of original images. According to test results we could limit image degradation by 1dB, avoid bit rate increment within 2% and increase processing time by only 2%. The IP is designed by Hynix 0.25 micron technology and the maximum operating frequency of 115MHz is achieved. The PSNR of the embedded watermark is about 35dB according to the test result.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.7
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• pp.1602-1608
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• 2013

PoC (Push-to-Talk over Cellular) provides one-to-one as well as one-to-many communications with VoIP technology based on SIP over cellular networks. According to above property, PoC is considered as perscrptive technology for public protection for disaster relief networks. For this networks, group communication is the essential function. However, since current standardization process takes into general scenarios account without any consideration for mentioned networks, it have some problems in the point of adaptability. To solve above problem, in this paper, we propose how to reduce the overhead on the PoC server to reduce the transmission delay. Simulation results are shown to evaluate the improved performance.

• Journal of Radiation Protection and Research
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• v.35 no.1
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• pp.26-33
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• 2010

A computed Radiography (CR) system by use of reusable Image Plate (IP) offers a convenient and reliable way to replace a conventional film-screen system for NDT (non-destructive testing) field. The quality of a radiography to detect a defect of welded objects depends on the procedure embracing several factors such as measurement conditions, image plate type/class, radiation energy, radiation type, and source to image plate distance. Also, the ability of images to detect a flaw reduces with increasing object thickness. In the study, the properties of gamma ray source were summarized for NDT field and inspection images of CR image system manufactured by FUJI were acquired using $^{75}Se$ and $^{192}Ir$ with welded objects. We analyzed the gray scale of hole defect image by using XCAP image processing program and calculated the image contrast and SNR in definition. Also the sesitivities of image quality indicator(IQI) were calculated for hot and cooling tube image of $^{75}Se$ and $^{192}Ir$.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.19 no.4
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• pp.125-135
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• 2009

Logs from various security system can reveal the attack trials for accessing private data without authorization. The logs can be a kind of confidence deriving factors that a certain IP address is involved in the trial. This paper presents a rule-based expert system for derivation of privacy violation confidence using various security systems. Generally, security manager analyzes and synthesizes the log information from various security systems about a certain IP address to find the relevance with privacy violation cases. The security managers' knowledge handling various log information can be transformed into rules for automation of the log analysis and synthesis. Especially, the coverage of log analysis for personal information leakage is not too broad when we compare with the analysis of various intrusion trials. Thus, the number of rules that we should author is relatively small. In this paper, we have derived correlation among logs from IDS, Firewall and Webserver in the view point of privacy protection and implemented a rule-based expert system based on the derived correlation. Consequently, we defined a method for calculating the score which represents the relevance between IP address and privacy violation. The UI(User Interface) expert system has a capability of managing the rule set such as insertion, deletion and update.

• Journal of Chest Surgery
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• v.32 no.9
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• pp.773-780
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• 1999

Background: It has been demonstrated that brief periods of calcium depletion and repletion (calcium-free preconditioning, CP) have cardioprotective effects as seen in ischemic preconditioning(IP) which enhances the recovery of post-ischemic contractile dysfunction and reduces the incidence of reperfusion-induced arrhythmia or infarct size after a prolonged ischemia. In the present study, we tested this paradoxical phenomenon in isolated rabbit hearts. Material and Method: Hearts isolated from New Zealand white rabbits(1.5∼2.0 Kg body weight) were perfused with Tyrode solution using the Langendorff technique. After stabilizing the baseline hemodynamics, the hearts were subjected to 45 minutes of global ischemia followed by 120 minutes of reperfusion with IP(IP group, n=7) or without IP (ischemic control group, n=7). IP was induced by a single episode of 5 minutes global ischemia and 10 minutes reperfusion. In the CP group(n=7), the hearts were subjected to perfusion with Tyrode solution with calcium depletion for 5 minutes and repletion for 10 minutes, and 45 minutes of ischemia and 120 minutes of reperfusion. Left ventricular function including developed pressure, dP/dt, heart rate, left ventricular end-diastolic pressure and coronary flow was measured. Infarct size was determined by staining with 1% triphenyltetrazolium chloride and planimetry. Data were analyzed by a one-way analysis of variance and Tukey's post-hoc test. Result: In comparison with the ischemic control group, IP significantly enhanced the recovery of the left ventricular function including the left ventricular developed pressure, contractility, and coronary flow; in contrast, these functional parameters of the CP group tended to be lower than those of the ischemic control group. However, the infarct size was significantly reduced by IP or CP(p<0.05). Conclusion: These results suggest that in isolated Langendorff-perfused rabbit heart model, CP(induced by single episode of 5 minutes calcium depletion and 10 minutes repletion) could not improve the post-ischemic contractile dysfunction(after a 45-minute global ischemia) but it has an infarct size-limiting effect.

• Environmental Analysis Health and Toxicology
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• v.29
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• pp.1.1-1.7
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• 2014

Objectives The present subacute study was designed to evaluate the effect of coenzyme Q 10 (CoQ10) in the 28 days aroclor 1254 exposure induced oxidative stress in mice brain. Methods Biochemical estimations of brain lipid peroxidation (LPO), reduced glutathione (GSH), and activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and acetyl cholinesterase (AChE), and histopathological investigations of brain tissue were carried out. Results Oral exposure of aroclor 1254 (5 mg/kg) led to significant decrease in levels of GSH, and activities of SOD, CAT, GPx, and AChE, and increase in LPO. These aberrations were restored by CoQ10 (10 mg/kg, intraperitoneal injection [IP]). This protection offered was comparable to that of L-deprenyl (1 mg/kg, IP) which served as a reference standard. Conclusions Aroclor 1254 exposure hampers the activities of various antioxidant enzymes and induces oxidative stress in the brains of Swiss albino mice. Supplementation of CoQ10 abrogates these deleterious effects of aroclor 1254. CoQ10 also apparently enhanced acetyl cholinesterase activity which reflects its influence on the cholinergic system.

• Convergence Security Journal
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• v.19 no.4
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• pp.77-85
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• 2019

As the Internet continues to evolve, cyber attacks are becoming more precise and covert. Anonymous communication, which is used to protect personal privacy, is also being used for cyber attacks. Not only it hides the attacker's IP address but also encrypts traffic, which allows users to bypass the information protection system that most organizations and institutions are using to defend cyber attacks. For this reason, anonymous communication can be used as a means of attacking malicious code or for downloading additional malware. Therefore, this study aims to suggest a method to detect and block encrypted anonymous communication as quickly as possible through artificial intelligence. Furthermore, it will be applied to the defense to detect malicious communication and contribute to preventing the leakage of important data and cyber attacks.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2003.10a
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• pp.199-202
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• 2003

IPsec is a standardization way for protection of IP packets in network layer and it is composed of three protocols that is AH(Authentication Header), ESP(Encapsulation Security Protocol) and IKE(Internet Key Exchange). Before doing encryption and decryption using AH or ESP protocols, both of communicating entities have to share same key safely. IKE protocol works automatically. But it has less interoperability because IKE protocol is not simple. A work which standardize IKEv2 has been done up to now. In this article, we will examine the Cryptographic Algorithms of IKEv2, and describe the AES usage with IPsec, based on the IETF Draft document.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.1
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• pp.466-483
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• 2017

Zen Cart is an open-source online store management system. It is used all over the world because of its stability and safety. Today, Zen Cart's session security mechanism is mainly used to verify user agents and check IP addresses. However, the security in verifying the user agent is lower and checking the IP address can affect the user's experience. This paper, which is based on the idea of session protection as proposed by Ben Adida, takes advantage of the HTML5's sessionStorage property to store the shared keys that are used in HMAC-SHA256 encryption. Moreover, the request path, current timestamp, and parameter are encrypted by using HMAC-SHA256 in the client. The client then submits the result to the web server as per request. Finally, the web server recalculates the HMAC-SHA256 value to validate the request by comparing it with the submitted value. In this way, the Zen Cart's open-source system is reinforced. Owing to the security and integrity of the HMAC-SHA256 algorithm, it can effectively protect the session security. Analysis and experimental results show that this mechanism can effectively protect the session security of Zen Cart without affecting the original performance.