• Title/Summary/Keyword: IME2

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A Specific Role of Ime2, Meiosis-specific Protein Kinase, in the Eary Meiotic Pathway in Saccharomyces cerevisiae (Saccharomyces cerevisiae의 감수분열 특이적 Protein Kinase인 Ime2의 역할)

  • Leem, Sun-Hee;Tak, Yon-Soo;Sunwoo, Yang-Il
    • Korean Journal of Microbiology
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    • v.35 no.4
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    • pp.258-265
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    • 1999
  • Entry into meiosis in the yeast Saccharomyces cerevisiae is regulated by two major factors: the cell type MATa/MAT${\alpha}$ and the nutriational state (starvation) of the cell. The two independent regulations act through IME1and IME2 expression to initiate meiosis. IME2 encodes a meiosis-specific protein kinase, and it enabled MATa/MAT${\alpha}$ diploid cells to undergo meiosis and sporulation. The PCR mutagenesis method was applied for the isolation of thermosensitive ime2 mutants. Among sixty two mutants isolated from the phenotype of defective spore formation under the restrictive temperature, three with the most easily observed temperature-sensitive phenotype (ts ${\cdot}$ime2-11, ts ${\cdot}$ime2-12 and ts ${\cdot}$ime2-13) were selected for further study. To understand the detailed functions of IME2, we examined the defects of these mutants in the early meiotic pathway including the premeiotic DNA replication and exhibited decreased level in meiotic recombination. These results suggest that the IME2 gene plays essential role in meiotic recombination pathway as well as premeiotic DNA replication. As the result of the IME2 overexpression in ${\Delta}$mre4. moreover, it was suggested that the IME2 and MRE4 genes act on the same pathway of initiation step in meiotic recombination.

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A STUDY ON STRESS DISTRIBUTION IN IMZ IMPLANT WITH A PLASTIC OR A TITANIUM IME USING FINITE ELEMENT ANALYSIS (유한요소법을 이용한 IMZ임플란트의 플라스틱 및 티타늄 IME의 응력분포에 관한 연구)

  • Ha Chi-Yang;Choi Boo-Byung;Woo Yi-Hyung
    • The Journal of Korean Academy of Prosthodontics
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    • v.31 no.4
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    • pp.625-642
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    • 1993
  • Whether stress-absorbing elements are functional in an implant system has been an issue of interest in oral implantology. The unique feature of the IMZ implant system is the planned imitation of the stress-distributing function of the structural unit of the tooth, periodontium, and alveolar bone through the use of an intramobile element(IME). The purpose of this study was to compare the difference in the displacement and the stress distibutions of IMZ implant with a polyoxymethylene(POM) or a titanium IME under static load. Two dimensional finite element analysis(FEA) was applied for this study and two finite element models were created. PATRAN program(DPA Co.,USA), a software for FEA, and SUN-SPARC2GX(SUN Co., USA), a workstation computer, were used. $1Kg/mm^2$ of static load was loaded individually on each three point of crown of implant prosthesis ; central fossa(load 1), mesial cusp tip(load 2), distal cusp tip(load 3), The displacements of X- and Y-axis and total displacement were measured at mesial and distal cusp tips, mesial and distal points between crown and IME, and implant apex. The von Mises stress was measured at mesial and distal points between crown and IME, mesial and distal points between IME and TIE, mesial and distal alveolar crest, the mesial and distal midpoints of implant, and implant apex. The difference in resultant values were compared and evaluated statistically using paired t-test. The results were as follows : 1. Under the load 1, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except total and Y-axis displacement at implant apex. And the differences in stress distributions with POM and titanium were varied. 2. Under the load 2, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except X-axis displacement at distal cusp tip. And the differences in stress distributions were varied. 3. Under the load 3, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except Y-axis displacement at mesial cusp tip. And the differences in stress distributions were varied. 4. For the displacement, there was significant difference statistically only in total displacement (P<0.1), but was no significant difference in X- and Y-axis displacement(P>0.1). For the stress, there was no significant difference among the compared values.

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Integer-Pel Motion Estimation for HEVC on Compute Unified Device Architecture (CUDA)

  • Lee, Dongkyu;Sim, Donggyu;Oh, Seoung-Jun
    • IEIE Transactions on Smart Processing and Computing
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    • v.3 no.6
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    • pp.397-403
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    • 2014
  • A new video compression standard called High Efficiency Video Coding (HEVC) has recently been released onto the market. HEVC provides higher coding performance compared to previous standards, but at the cost of a significant increase in encoding complexity, particularly in motion estimation (ME). At the same time, the computing capabilities of Graphics Processing Units (GPUs) have become more powerful. This paper proposes a parallel integer-pel ME (IME) algorithm for HEVC on GPU using the Compute Unified Device Architecture (CUDA). In the proposed IME, concurrent parallel reduction (CPR) is introduced. CPR performs several parallel reduction (PR) operations concurrently to solve two problems in conventional PR; low thread utilization and high thread synchronization latency. The proposed encoder reduces the portion of IME in the encoder to almost zero with a 2.3% increase in bitrate. In terms of IME, the proposed IME is up to 172.6 times faster than the IME in the HEVC reference model.

Comparative Analysis of the Independent Medical Examination Reports and Legal Decisions in Pain Medicine

  • Nahm, Francis Sahn-Gun;Lee, Pyung-Bok;Kim, Tae-Hun;Kim, Yong-Chul;Lee, Chul-Joong
    • The Korean Journal of Pain
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    • v.23 no.1
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    • pp.28-34
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    • 2010
  • Background: An independent medical examination (IME) is a critical process for awarding reparation for injury. However, conducting an IME in pain medicine is very difficult, not only because pain is a subjective symptom, but also because there are no proper objective methods to demonstrate it. This study was conducted to compare IME reports and the court decisions on the disability status of the patients. Methods: We analyzed 79 IME reports and 25 corresponding court decisions on the disability status of patients. The diagnoses, causal relationships between the patients' status and the trauma, McBride's degree of disability, the American Medical Association's impairment ratings, the estimated annual cost for future treatment, and the necessity of care-giving were compared and analyzed. Results: The diagnoses in the 79 cases were complex regional pain syndrome (CRPS) type I (58 cases), CRPS type II (7 cases), peripheral neuropathy (5 cases), myofascial pain syndrome (4 cases), herniated intervertebral disc (2 cases), and fibromyalgia (1 case). The types of accidents were road traffic accidents (50 cases), military injuries (14 cases), industrial accidents (11 cases), and others (4 cases). The IME reports and the court decisions stated considerably different McBride's degrees of disability (P = 0.014). However, there was no significant difference in the estimated cost for future treatment between the IME reports and the court decisions (P = 0.912). Conclusions: IME reports should be accurate, fair, and based on objective findings. Feedback on IMEs from the court decisions is helpful for reference use.

A Study on Characteristics of Industrial Structure by Shift-Share Analysis : The Case of Chungnam Geumgang Area (변이할당분석을 이용한 충청남도 금강권 산업구조 특성 분석)

  • Kim, Sung-Rok;Lee, Jong-Sang
    • Journal of Korean Society of Rural Planning
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    • v.20 no.1
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    • pp.127-134
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    • 2014
  • This study, in order to complement instability of analysis result stemming from the choice between reference point and comparison point which is pointed out as the defect of shift-share analysis, conducted shift-share analysis using Gross Regional Domestic Product (GRDP) trend of Geumgang area, Chungcheongnam-do for the period from 2000 to 2011. As a result of the analysis, (1) industries that had both the positive Regional Share Effect (RSE) and Industrial Mixed Effect (IME) were service industries such as manufacturing industry, electricity gas, transportation industry, art, etc., which are positively influencing the regional industry. (2) industries that had both the negative RSE and IME were other service industries such as wholesale and retail businesses, lodging industry, food industry, real estate business and leasing service, business service industry, public administration, etc., which provide basic livelihood services for the residents. (3) industries that had the positive RSE and negative IME were agriculture, forestry and fishery industry, mining industry, construction industry, and educational service industry. (4) industries that had the negative RSE and positive IME were info-communications industry, financial and insurance businesses, health industry, etc.

Novel IME Instructions and their Hardware Architecture for Fast Search Algorithm (고속 탐색 알고리즘에 적합한 움직임 추정 전용 명령어 및 구조 설계)

  • Bang, Ho-Il;SunWoo, Myung-Hoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.48 no.12
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    • pp.58-65
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    • 2011
  • This paper presents an ASIP (Application-specific Instruction Processor) for motion estimation that employs specific IME instructions and its programmable and reconfigurable hardware architecture for various video codecs, such as H.264/AVC, MPEG4, etc. With the proposed specific instructions and variable point 2D SAD hardware accelerator, it can handle the real-time processing requirement of High Definition (HD) video. With the SAD unit and its parallel operations using pattern information, the proposed IME instructions support not only full search algorithms but also other fast search algorithms. The hardware size is 25.5K gates for each Processing Element Group (PEG) which has 128 SAD Processor Elements (PEs). The proposed ASIP has been verified by the Synopsys Processor Designer and implemented by the Design Compiler using the IBM 90nm process technology. The hardware size is 453K gates for the IME unit and the operating frequency is 188MHz for 1080p@30 frame in real time. The proposed ASIP can reduce the hardware size about 26% and the number of operation cycles about 18%.

METABOLIZABLE ENERGY REQUIREMENTS FOR MAINTENANCE AND GROWTH OF SUCKLING CALVES GIVEN MILK REPLACER

  • Sekine, J.;Oura, R.;Morita, Z.;Morooka, T.;Asahida, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.1 no.2
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    • pp.61-63
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    • 1988
  • A total of 38 energy balance trials were done for calves fed a liquid milk replacer, calf starter and second cut mixed hay. Milk replacer supplied 81% of the total dietary energy. Live weight of calves averaged 54.1 (S.D 6.2) kg and daily gain 0.37 (${\pm}0.23$)kg. The metabolizability of gross energy averaged 0.822. A regression was calculated relating energy retention (ER, $kJ/kg^{0.75}$) to the intake of metabolizable energy (IME, $kJ/kg^{0.75}$): ER = 0.72 (${\pm}0.12$) IME - 330, r = 0.702, P < 0.01, $S.E.{\pm}18.0$. Metabolizable energy for maintenance (MEm) was calculated to be $458kJ/kg^{0.75}$ when ER = 0. The amount of IME over MEm for an individual animal (Meg, $kJ/kg^{0.75}$) was regressed on averaged daily gain (ADG, kg): Meg = 413 (${\pm}91$) ADG + 0.2, r = 0.650, P < 0.01, $S.E.{\pm}21$. The amount of ME requirement for suckling calves was estimated using values obtained above.

Recent Progress in Micro In-Mold Process Technologies and Their Applications (마이크로 인몰드 공정기술 기반 전자소자 제조 및 응용)

  • Sung Hyun Kim;Young Woo Kwon;Suck Won Hong
    • Journal of the Microelectronics and Packaging Society
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    • v.30 no.2
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    • pp.1-12
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    • 2023
  • In the current era of the global mobile smart device revolution, electronic devices are required in all spaces that people interact with. The establishment of the internet of things (IoT) among smart devices has been recognized as a crucial objective to advance towards creating a comfortable and sustainable future society. In-mold electronic (IME) processes have gained significant industrial significance due to their ability to utilize conventional high-volume methods, which involve printing functional inks on 2D substrates, thermoforming them into 3D shapes, and injection-molded, manufacturing low-cost, lightweight, and functional components or devices. In this article, we provide an overview of IME and its latest advances in application. We review biomimetic nanomaterials for constructing self-supporting biosensor electronic materials on the body, energy storage devices, self-powered devices, and bio-monitoring technology from the perspective of in-mold electronic devices. We anticipate that IME device technology will play a critical role in establishing a human-machine interface (HMI) by converging with the rapidly growing flexible printed electronics technology, which is an integral component of the fourth industrial revolution.

Wang-ime Oreum Flora on Jeju Island (제주도 왕이메오름의 식물상)

  • Jee-Hyun Park;Min-Hee Seo;Sung-Pil Moon;Gwanpil Song
    • Journal of Environmental Science International
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    • v.32 no.12
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    • pp.861-881
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    • 2023
  • This study investigated the flora of the Wang-ime oreum located on Seogwipo-si, Jeju-do, to basic data for the Jeju Island plant distribution. A total of 366 taxa were found with 94 families, 240 genera, 358 species, 1 subspecies, 6 varieties, and 1 forma. The floristic target species in Korea appeared as 2 taxa of grade V, 13 taxa of grade IV, 46 taxa of grade III, 5 taxa of grade II, and 49 taxa of grade I. There were 14 taxa for naturalized plants. The different plant life forms that appeared were large ground plants (M)(54 taxa), small land plants (N) (52 taxa), epiphyte (E) (6 taxa), indicator plants (Ch) (4 taxa), and semi-aquatic plants (H) (168 taxa), There were 34 and 48 taxa of plants(G) and annuals (Th) respectively. From these results, Wang-ime oreum, which is adjacent to ranches and grasslands, has little artificial interference, as more plants are distributed, and fewer naturalized plants are found than in Suwolbong and Dangsanbong. Accordingly, each oreum plays an important role in the flora of Jeju-do, thus a management plan tailored to the characteristics of the volcano is necessary.