• The Bulletin of The Korean Astronomical Society
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• v.43 no.2
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• pp.48.1-48.1
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• 2018

We report on a series of science articles presented in the Children's magazine 고래가그랬어. The monthly articles (appearing since 2016) highlight current issues in Physics and Astronomy with particular emphasis on science being conducted in Korea. Reporting is performed by interviewing experts in their respective fields. In an effort to encourage children to envisage themselves as scientists, interviews are taken predominantly from Korean early-career researchers. Gender balance is obtained through a careful selection of interviewees ensuring that children are exposed to a broad cross-section of science researchers. This series has introduced children to the 1st detection of Gravitational Waves, the KMTnet telescope system, the Korean Very Long Baseline Interferometric Network, KGMT, IBS Axion experiments, and many other experiments and discoveries.

• 축산식품과학과 산업
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• v.10 no.2
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• pp.42-52
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• 2021

• The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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• v.31 no.5
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• pp.42-47
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• 2002

건물의 고도화 및 최첨단 공조시스템에 있어서 공기 조화기는 가장 핵심적인 장비로서 고장의 전도는 비교적 단순하나 요소기술의 적용, 운전, 유지관리에서 소홀하게 되 면 환경 업무의 저하와 생산성이 낮아지고 막대한 비용을 초래하기도 한다 . 고장은 설비시스템과 공조기의 사용기간이 길어짐에 따라 마모, 피로 등의 물리적 성능열화가 진행되며 이러한 물리적 열화가 최종적으로 나타나는 현상이 고장이다. 고장의 시간적 변화에는 초기고장, 우발고장, 마모고장으로 분류되며 초기고장은 시스템의 불안정에 따른 원인으로 시운전시에 자주 발생하고 정상적인 운전시에 발생되는 우발고장이 기간이 지나면 마모 고장기에 도달하게되며 이때는 부품의 한계수명과 마모등의 원인으로 고장률이 급격히 증가된다 따라서 본문에서는 공조시스템의 공기조차기의 팬과 펌프 기기의 고장원인을 살펴보고 이에 대한 고장을 신속하게 감시할 수 있는 방안을 일반적일 고찰을 통해 체계적이고 종합적인 대응방안을 소개하여 불필요한 보수비용의 발생과 생산성 저하를 방지하고 내구년수를 증가할 수 있는 신기술의 일부분을 소개하고자 한다.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.2
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• pp.56.1-56.1
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• 2019

We are producing and consuming more data than ever before. Massive data allow us to better understand the world around us, yet they bring a new set of challenges due to their inherent noise and sheer enormity in size. Without smart algorithms and infrastructures, big data problems will remain intractable, and the same is true in natural science research. The mission of data science as a research field is to develop and apply computational methods in support of and in the replacement of costly practices in handling data. In this talk, I will introduce how data science and deep learning has been used for solving various problems in natural sciences. In particular, I will present a case study of analyzing high-resolution satellite images to infer socioeconomic scales of developing countries.

• Proceedings of the Korea Information Processing Society Conference
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• 2021.11a
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• pp.993-996
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• 2021

챗봇의 사용 용도는 일상 대화와 소비자 응대를 넘어서 심리 상담 용도로 확장하고 있다. 이 연구에서는 챗봇-사람 채팅에서 무작위로 추출한 '우울'과 관련된 대화 데이터를 텍스트마이닝 기법으로 분석하여 채팅에서의 우울 관련 담론 주제를 파악하였다. 더불어 정성 분석을 통해 사용자들이 챗봇에 털어놓고 있는 '우울' 의 종류를 범주화하고 분류하여, 트위터의 '우울' 데이터와의 차이점을 비교하였다. 이를 통해 챗봇 데이터의 '우울' 대화만의 특징을 파악하고, 우울 증상 탐지와 그에 따른 적절한 심리지원 정보를 제공하는 서비스 디자인의 착안점을 제시한다.

• Korean Journal of Radiology
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• v.21 no.7
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• pp.779-792
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• 2020

Recent advances in computer technology have generated a new area of research known as radiomics. Radiomics is defined as the high throughput extraction and analysis of quantitative features from imaging data. Radiomic features provide information on the gray-scale patterns, inter-pixel relationships, as well as shape and spectral properties of radiological images. Moreover, these features can be used to develop computational models that may serve as a tool for personalized diagnosis and treatment guidance. Although radiomics is becoming popular and widely used in oncology, many problems such as overfitting and reproducibility issues remain unresolved. In this review, we will outline the steps of radiomics used for oncology, specifically addressing applications for breast cancer patients and focusing on technical issues.

• Journal of Microbiology and Biotechnology
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• v.30 no.10
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• pp.1480-1487
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• 2020

Our previous report determined that miR-144 is a key regulator of intestinal epithelial permeability in irritable bowel syndrome with diarrhea (IBS-D) rats. Recent evidence has shown that lactobacilli play an important role in the relief of IBS-D symptoms. However, few studies have addressed the mechanisms by which microRNAs and lactobacilli exert their beneficial effects on intestinal epithelial permeability. Hence, to elucidate whether miRNAs and lactobacilli play roles in intestinal epithelial barrier regulation, we compared miRNA expression levels in intestinal epithelial cells (IECs) under Lactobacillus casei (L. casei LC01) treatment. IECs and L. casei LC01 were co-cultured and then subjected to microRNA microarray assay. qRT-PCR, western blot and ELISA were used to detect the expression of occludin (OCLN) and zonula occludens 1 (ZO1/TJP1). The interaction between miRNAs and L. casei LC01 acting in IECs was investigated through transfection of RNA oligoribonucleotides and pcDNA 3.1 plasmid. The results are as follows: 1) L. casei LC01 decreased the expression of miR-144 and FD4 and promoted OCLN and ZO1 expression in IECs; 2) L. casei LC01 enhanced the barrier function of IECs via downregulation of miR-144 and upregulation of OCLN and ZO1; 3) Under L. casei LC01 treatment, OCLN and ZO1 overexpression could partially eliminate the promoting effect of miR-144 on intestinal permeability in IECs. Our results demonstrate that L. casei LC01 regulates intestinal permeability of IECs through miR-144 targeting of OCLN and ZO1. L. casei LC01 can be a possible therapeutic target for managing dysfunction of the intestinal epithelial barrier.

• Molecules and Cells
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• v.43 no.4
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• pp.360-372
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• 2020

The basal ganglia network has been implicated in the control of adaptive behavior, possibly by integrating motor learning and motivational processes. Both positive and negative reinforcement appear to shape our behavioral adaptation by modulating the function of the basal ganglia. Here, we examined a transgenic mouse line (G2CT) in which synaptic transmissions onto the medium spiny neurons (MSNs) of the basal ganglia are depressed. We found that the level of collaterals from direct pathway MSNs in the external segment of the globus pallidus (GPe) ('bridging collaterals') was decreased in these mice, and this was accompanied by behavioral inhibition under stress. Furthermore, additional manipulations that could further decrease or restore the level of the bridging collaterals resulted in an increase in behavioral inhibition or active behavior in the G2CT mice, respectively. Collectively, our data indicate that the striatum of the basal ganglia network integrates negative emotions and controls appropriate coping responses in which the bridging collateral connections in the GPe play a critical regulatory role.

• Journal of the Korean Society of Marine Environment & Safety
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• v.11 no.2 s.23
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• pp.33-40
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• 2005

According to the development of technology of the navigational equipments, many bridge equipments have been improved, however, marine accidents by human error have not been reduced. Therefore, a matter of primary concern is focused on whether bridge equipments of ships are ergonomically arranged to reduce errors due to human factors. As part of a design of IBS(Integrated Bridge System) standard, rules of the conning display to save time and additional movements to obtain important informations of a ship should be established as soon as possible. In the present study, ergonomic design factors for the conning display are studied through the survey of related works, heuristic evaluations, sketch method tests as well as questionnaires. Using these factors, new conning display was designed and the ergonomic indices were evaluated by comparing tests of the existing conning displays. It is found that the designed conning display obtained high ergonomic index showed better performance, therefore, the ergonomic index studied in the present paper can be used as a useful design standard in the conning display design procedures.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.28 no.4
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• pp.121-132
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• 2023

Marine heatwaves (MHWs), referring to anomalously high sea surface temperatures, have drawn significant attention from marine scientists due to their broad impacts on the surface marine ecosystem, fisheries, weather patterns, and various human activities. In this study, we examined the impact of the distribution of Changjiang diluted water (CDW), a significant factor causing oceanic property changes in the East China Sea (ECS) during the summer, on MHWs. The surface salinity distribution in the ECS indicates that from June to August, the eastern extension of the CDW influences areas as far as Jeju Island and the Korea Strait. In September, however, the CDW tends to reside in the Changjiang estuary. Through the Empirical Orthogonal Function analysis of the cumulative intensity of MHWs during the summer, we extracted the loading vector of the first mode and its principal component time series to conduct a correlation analysis with the distribution of the CDW. The results revealed a strong negative spatial correlation between areas of the CDW and regions with high cumulative intensity of MHWs, indicating that the reinforcement of stratification due to low-salinity water can increase the intensity and duration of MHWs. This study suggests that the CDW may still influence the spatial distribution of MHWs in the region, highlighting the importance of oceanic environmental factors in the occurrence of MHWs in the waters surrounding the Korean Peninsula.