• 한국전문물리치료학회지
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• 제13권3호
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• pp.102-110
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• 2006

To improve trunk stability, various exercise protocols were introduced into the clinical field. Trunk and lumbar stability exercises on unstable surfaces are especially recommended to improve lumbar stability. The purpose of this study was to compare abdominal oblique muscle activity during leg raising in hook-lying position among 3 different type of surface conditions (on floor (F), vestibular board (VB), and foam roll (FR)). Sixteen able-bodied volunteers, who had no medical history of lower extremity or lumbar spine disease, were recruited for this study. Surface electromyography (EMG) activity was recorded from the internal and external oblique muscles of both sides. The normalized EMG activity was compared using a one-way repeated ANOVA. The results showed that the EMG activities of the internal oblique and external oblique of the lifted leg side during straight leg raising significantly increased under the FR condition when compared to the F condition. There was no significant difference of the EMG activity in abdominal oblique muscles between the VB and the FR conditions. The EMG activity of the internal oblique of supported leg side during the straight leg raising was significantly greater under the FR condition than the VB and F conditions (p<.05). The composition ratio of EMG activity of internal oblique muscles during straight leg raising was significantly increased under the FR condition. Therefore, straight leg raising exercise on foam roll in hook lying position could be beneficial to improve trunk and lumbar stability.

• IMMUNE NETWORK
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• 제9권6호
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• pp.265-273
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• 2009

Foot-and-mouth disease virus (FMDV) is a small single-stranded RNA virus which belongs to the family Picornaviridae, genus Apthovirus. It is a principal cause of FMD which is highly contagious in livestock. In a wild type virus infection, infected animals usually elicit antibodies against structural and non-structural protein of FMDV. A structural protein, VP1, is involved in neutralization of virus particle, and has both B and T cell epitopes. A RNA-dependent RNA polymerase, 3D, is highly conserved among other serotypes and strongly immunogenic, therefore, we selected VP1 and 3D as vaccine targets. VP1 and 3D genes were codon-optimized to enhance protein expression level and cloned into mammalian expression vector. To produce recombinant protein, VP1 and 3D genes were also cloned into pET vector. The VP1 and 3D DNA or proteins were co-immunized into 5 weeks old BALB/C mice. Antigen-specific serum antibody (Ab) responses were detected by Ab ELISA. Cellular immune response against VP1 and 3D was confirmed by ELISpot assay. The results showed that all DNA- and protein-immunized groups induced cellular immune responses, suggesting that both DNA and recombinant protein vaccine administration efficiently induced Ag-specific humoral and cellular immune responses.

• JSTS:Journal of Semiconductor Technology and Science
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• 제16권2호
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• pp.198-203
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• 2016

We investigate the effects of magnesium (Mg) suppressor layer on the electrical performances and stabilities of amorphous indium-zinc-tin-oxide (a-ITZO) thin-film transistors (TFTs). Compared to the ITZO TFT without a Mg suppressor layer, the ITZO:Mg TFT exhibits slightly smaller field-effect mobility and much reduced subthreshold slope. The ITZO:Mg TFT shows improved electrical stabilities compared to the ITZO TFT under both positive-bias and negative-bias-illumination stresses. From the X-ray photoelectron spectroscopy O1s spectra with fitted curves for ITZO and ITZO:Mg films, we observe that Mg doping contributes to an enhancement of the oxygen bond without oxygen vacancy and a reduction of the oxygen bonds with oxygen vacancies. This result shows that the Mg can be an effective suppressor in a-ITZO TFTs.

• JSTS:Journal of Semiconductor Technology and Science
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• 제16권2호
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• pp.172-178
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• 2016

In this paper, we propose a sub-10 nm Ge/GaAs heterojunction-based tunneling field-effect transistor (TFET) with vertical band-to-band tunneling (BBT) operation for ultra-low-power (LP) applications. We design a stack structure that is based on the Ge/GaAs heterojunction to realize the vertical BBT operation. The use of vertical BBT operations in devices results in excellent subthreshold characteristics with a reduction in the drain-induced barrier thinning (DIBT) phenomenon. The proposed device with a channel length ($L_{ch}$) of 5 nm exhibits outstanding LP performance with a subthreshold swing (S) of 29.1 mV/dec and an off-state current ($I_{off}$) of $1.12{\times}10^{-11}A/{\mu}m$. In addition, the use of the highk spacer dielectric $HfO_2$ improves the on-state current ($I_{on}$) with an intrinsic delay time (${\tau}$) because of a higher fringing field. We demonstrate a sub-10 nm LP switching device that realizes a good S and lower $I_{off}$ at a lower supply voltage ($V_{DD}$) of 0.2 V.

• 한국건축시공학회지
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• 제18권2호
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• pp.99-107
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• 2018

이 연구의 목적은 기존 철근콘크리트 기둥의 내진보강을 위한 단면 확대보강공법에서 보조 띠철근으로써 배근할 수 있는 V-타이의 상세를 제시하는 것이다. 모두 24개의 직접 인발실험체에서 V-타이의 역학적 거동을 고려한 부착강도 관점에서 선택한 주요 변수는 V-타이의 형상, 묻힘길이 및 콘크리트 강도이다. 다양한 상세를 갖는 V-타이의 부착강도는 일반 V-타이의 부착강도 및 CEB-FIP 제안식과 비교하였다. 그 결과 보강단면의 두께가 기존 V-타이의 묻힘 길이[= max(75mm, $6d_b$)]보다 적은 기둥의 경우 단부 압착형의 V-타이가 보조 띠철근로 추천될 수 있었는데, 여기서 $d_b$는 V-타이로 사용된 철근의 직경이다.

• 환경영향평가
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• 제26권5호
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• pp.303-314
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• 2017

이 연구의 목적은 국내 외 생태자산 관련 연구 경향을 파악하는 것이다. 생태자산과 의미가 유사한 12개 키워드와 연관 있는 분야 및 영역들을 확인하면서 연구흐름을 이해하고자 하였다. 우리는 키워드 네트워크 분석을 이용하여 방대하게 이루어지고 있는 국내외 연구들을 분석하였다. 키워드 네트워크 분석은 정보의 구조적 흐름을 이해하고 방향성을 파악하는데 유용하다. 국외 연구들은 지속가능성을 중심으로 보전, 경제적 평가, 관리, 정책 분야로 연결되는 것을 보았다. 국내연구 분석은 문헌자료가 적어 다양한 흐름들을 확인하기 어려웠으나 지역의 활성화를 위해 경제적인 가치를 확인하고자 하는 연구들이 있었다. 이 연구는 향후 국내 생태자산 관련 연구 방향들에 설정하는데 활용할 수 있다.

• 한국약용작물학회지
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• 제19권2호
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• pp.77-82
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• 2011

The antioxidative activity of various enzymatic extracts from Sarcodon aspratus (S. aspratus) was evaluated by measuring 1,1-diphenyl-2-picrylhydrazyl (DPPH), and alkyl radical scavenging activity using an electron spin resonance (ESR) spectrometer. For this study, the S. aspratus were enzymatically hydrolyzed by seven carbohydrases (Viscozyme, Celluclast, Dextrozyme, AMG, Promozyme, Maltogenase, and Termamyl) and eight proteases (${\alpha}$-chymotrypsin, Alcalase, Flavourzyme, Neutrase, papain, pepsin, Protamax, and trypsin). The DPPH radical scavenging activities of Viscozyme and pepsin extracts were the highest, and the half maximal inhibitory concentration ($IC_{50}$) values were 0.896 and 0.734mg/mL, respectively. The Celluclast and trypsin extracts showed the highest scavenging activities on alkyl radical, and their $IC_{50}$ values were 0.278 and 0.575mg/mL, respectively. The Celluclast extracts was decreased cell apoptosis in PC-12 cells against $H_2O_2$-induced oxidative damage. The findings of the present study suggest that enzymatic extracts of S. aspratus exhibit antioxidative activity against oxidative stress on PC-12 cells.

• 한국가스학회지
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• 제15권5호
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• pp.19-24
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• 2011

최근 산업구조가 미래 첨단산업 위주로 전환되면서 자동차를 비롯한 항공기, 휴대폰, 전자기기 등 다양한 산업분야의 제품에 Al, Mg, Li, Zn과 같은 가연성 금속의 사용량이 크게 증가하고 있으며 이러한 가연성 금속의 가공과 정에서 발생하는 금속분진에 의한 폭발 사고 또한 증가하고 있다. 금속분진에 의한 폭발사고는 가연성 금속분진을 포집 및 저장하는 국소배기설비의 공기정화장치에서 대부분 발생함에 따라 공기정화장치내 폭발 발생시 폭발압력에 의한 공기정화장치 구조물의 변형과 파열형태를 단순 예측이 아닌 유한요소해석(FEA)법에 의해 기술적으로 분석 및 제시하고자 본 연구를 수행하였다.

• 한국가스학회지
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• 제16권5호
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• pp.58-65
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• 2012

현재 가연성 가스의 누출시 누출된 가스의 확산과 VCE에 의한 과압을 예측하기 위해 여러 모델들이 이용되고 있다. 그러나 이 모델들은 누출설비의 지형과 장애물 그리고 건물들의 영향에 대해서는 충분히 고려하지 않은 단순한 접근방법을 이용하고 있다. 이에 본 연구는 누출된 물질의 연소형태, 설비의 Geometry, 난류, 장애물, 바람의 영향 등 여러 변수를 고려하여 보다 정확하게 분석할 수 있는 CFD(Computational Fluid Dynamics) Model을 검토함으로서 누출된 가스의 확산과정과 분포형태 그리고 폭발시 화염과 과압의 결과를 2D와 3D의 가상공간에서 제시하였다. 이러한 CFD 분석결과는 폭발에 대한 리스크 분석과 리스크 기반의 설계에 있어 유용하게 활용될 것으로 판단된다.

• 대한세포병리학회지
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• 제15권2호
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• pp.126-130
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• 2004

Granular cell tumor is characterized by large eosinophilic cells with granular appearances. These are mostly benign. Approximately $1\sim2%$ are malignant, and establishment of reliable criteria for diagnosing malignant granular cell tumor has been difficult to establish because oi the rarify. Reports on the cytologic features of this neoplasm are hardly found in Korea. We report a case of rarely-occurring granular cell tumor in the lower leg of a 40-year-old male, diagnosed on fine needle aspiration cytology, together with a review of the literature regarding significant adverse histology and prognostic factors. The aspirates revealed cellular smears of isolated cells, syncytial clusters, and occasionally stripped nuclei in a nine, bluish-purple, granular background. Tumor cells were polygonal, rounded, or slightly spindled, and showed ill-defined granular cytoplasm. Nuclei were small and round or oval, with inconspicuous or small, prominent nucleoli. The nuclei showed rare intranuclear cytoplasmic invagination. Occasionally, there were mild to moderate nuclear pleomorphisms with vesicular nuclei, with large, prominent nucleoi, but no mitosis. The immunocytochemical stain for S-100 was strongly positive in the cytoplasm of tumor cells with occasional nuclei.