• Journal of Microbiology and Biotechnology
• /
• v.13 no.4
• /
• pp.613-619
• /
• 2003

The polyketide backbone of rifamycin B is assembled by the type I rifamycin polyketide synthase (PKS) encoded by the rifA-rifE genes. In order to produce novel analogs of rifamycin via engineering of the PKS genes, inactivation of the ${\beta}-ketoacyl:acyl$ carrier protein reductase (KR) domain in module 8 of rifD, by site-specific mutagenesis of the NADPH binding site, was attempted. Module 8 contains a nonfunctional dehydratase (DH) domain and a functional KR domain that is involved in the reduction of the ${\beta}-carbonyl$ group, resulting in the C-21 hydroxyl of rifamycin B. This mutant strain produced linear polyketides, from tetraketide to octaketide, which were also produced by a rifD-disruption mutant as a consequence of premature termination of the polyketide assembly. Another attempt to replace the DH domain of module 7, which has been considered nonfunctional, with a functional homolog derived from module 7 of rapamycin-producing PKS also resulted in the production of linear polyketides, including the heptaketide intermediate and its precursors. Premature release of the carbon chain assembly intermediates is an unusual property of the rifamycin PKS. that is not seen in other PKSs such as the erythromycin PKS.

• Journal of Power Electronics
• /
• v.19 no.4
• /
• pp.907-921
• /
• 2019

This paper presents two advanced hybrid pulse-width modulation (PWM) strategies for multilevel inverters (MLIs) that provide both common-mode voltage (CMV) elimination and current ripple reduction. The first PWM utilizes sequences that apply one switching state at the double ends of a half-carrier cycle. The second PWM combines the advantages of the former and an existing four-state PWM. Analyses of the harmonic characteristics of the two groups of switching sequences based on a general switching voltage model are carried out, and algorithms to optimize the current ripple are proposed. These methods are simple and can be implemented online for general n-level inverters. Using a three-level NPC inverter and a five-level CHB inverter, good performances in terms of the root mean square current ripple are obtained with the proposed PWM schemes as indicated through improved harmonic distortion factors when compared to existing schemes in almost the entire region of the modulation index. This also leads to a significant reduction in the current total harmonic distortion. Simulation and experimental results are provided to verify the effectiveness of the proposed PWM methods.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.41 no.1
• /
• pp.70-77
• /
• 2005

The study was results obtained from the trial make of the hybrid GPS-electromagnetic(EM) compass which overcome shortcoming of GPS compass and EM compass. The results were summarized as follows: GPS compass detected the stable ship's heading at 0.1^{\circ}$ intervals with the turning angular velocity of less than 25^{\circ}$/sec in the experiment for the characteristics of turning angular velocity with stepmotor, but in case of over 25^{\circ}$/sec the compass did not detect it. On the contrary, the EM compass always indicated the ship's heading with no connection of the turning angular velocity, however the compass is low accuracy compared with GPS one owing to a compass error. The ship's headings by the hybrid GPS-EM compass were displayed at fixed point and moving by car; if the GPS compass work the headings were displayed by GPS compass, if not, the heading is provided stably by adding or subtracting of a compass error to the heading of EM compass. Also, each ship's heading was derived from not only the GPS compass but also the EM one by add or subtract of the compass errors, and then was worked covariance for the analogy. The results show that the ship's heading of two compasses has been verified the similarity to 95% confidence level.

• Journal of the Korean Society for information Management
• /
• v.31 no.1
• /
• pp.77-97
• /
• 2014

It is necessary to find the practical considerations for applying RDA in building up the bibliographic records by importing RDA records from LC or OCLC in Korea. Especially, it is not easy to apply RDA appropriately because there are many alternatives and options in RDA. Therefore, this study is to grasp the way for applying RDA in building up the bibliographic records by reviewing LC RDA guidelines and analyzing RDA cataloging policies of libraries such as University of Chicago, North Carolina State University, and Standford University. As a result, these libraries have catalogued according to LC RDA guidelines and each library has its own guidelines, i.e., in statement of responsibilities, to transcribe all but exceptionally allow to transcribe only first, in publication statement, to use 264 field or 260 field, and in resource types, to transcribe all types of content, media and carrier or to transcribe 33X with GMD. Therefore followings would be considered for RDA application. First, some variations could be allowed for special situations of libraries in applying RDA and LC RDA guidelines. Second, the hybrid records that describe the core element of RDA to non-RDA records would be written in processing AACR2 to RDA. Third;the display of 33X field would be designed for expressing the resource types.

• Journal of Korean Society of Transportation
• /
• v.22 no.2 s.73
• /
• pp.145-154
• /
• 2004

The growing demand for customer-responsive, made-to-order manufacturing is stimulating the need for improved dynamic decision-making processes in commercial fleet operations. Moreover, the rapid growth of electronic commerce through the internet is also requiring advanced and precise real-time operation of vehicle fleets. Accompanying these demand side developments/pressures, the growing availability of technologies such as AVL(Automatic Vehicle Location) systems and continuous two-way communication devices is driving developments on the supply side. These technologies enable the dispatcher to identify the current location of trucks and to communicate with drivers in real time affording the carrier fleet dispatcher the opportunity to dynamically respond to changes in demand, driver and vehicle availability, as well as traffic network conditions. This research investigates key aspects of real time dynamic routing and scheduling problems in fleet operation particularly in a truckload pickup-and-delivery problem under various settings, in which information of stochastic demands is revealed on a continuous basis, i.e., as the scheduled routes are executed. The most promising solution strategies for dealing with this real-time problem are analyzed and integrated. Furthermore, this research develops. analyzes, and implements hybrid algorithms for solving them, which combine fast local heuristic approach with an optimization-based approach. In addition, various partitioning algorithms being able to deal with large fleet of vehicles are developed based on 'divided & conquer' technique. Simulation experiments are developed and conducted to evaluate the performance of these algorithms.

• Journal of Navigation and Port Research
• /
• v.26 no.1
• /
• pp.22-27
• /
• 2002

The 25 Watt hybrid MIC SSPA has been developed in the frequency rang from 1.6265 GHz to 1.6465 GHz for uplink of INMARST's earth station. To simplify the fabrication process, the whole system is designed of two parts composed of a friving amplifier and a power amplifier. The Motorolas MRF-6401 is used for driving part, the Motorolas MRF-16006 and MRF-16030 is used the power amplifier. We reduced weight and volume of high power amplifier through arranging the bias circuits in the same housing. The realized SSPA has more than 30 dB for gain within 20 MHz bandwidth, and the voltage standing wave ratios(VSWR) of input and output port are less than 1.7, respectively. The output power of 44 dBm is achieved at the 1 dB gain compression point of 106365 GHz These results reveal a high power amplifier of 25 Watt which is the design target. The Proposed SSPA manufacture techniques in this paper can be applied to the implementation of high power amplifiers for some radars and SCPC.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.32 no.2C
• /
• pp.95-112
• /
• 2007

Spatial Multiplexing techniques, which is a kind of Multiple antenna techniques, provide high data transmission rate by transmitting independent data at different transmit antenna with the same spectral resource. OFDM (Orthogonal Frequency Division Multiplexing) is applied to MIMO (Multiple-Input Multiple-Output) system to combat ISI (Inter-Symbol Interference) and frequency selective fading channel, which degrade MIMO system performance. But, orthogonality between subcarriers of OFDM can't be guaranteed under high-mobility condition. As a result, severe performance degradation due to ICI is induced. In this paper, both ICI and CAI (Co-Antenna Interference) which occurs due to correlation between multiple antennas, and performance degradation due to both ICI and CAI are analyzed. In addition to the proposed CIR (Channel Impulse Response) estimation method for avoiding loss in data transmission rate, HIC (Hybrid Interference Cancellation) approach for guaranteeing QoS of MIMO-OFDM receiver is proposed. We observe the results on analytical performance degradation due to both ICI & CAI are coincide with the simulation results and performance improvement due to HIC are also verified by simulation under SCM-E Sub-urban Macro MIMO channel.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.17 no.10 s.113
• /
• pp.959-966
• /
• 2006

This paper proposes a new concept about dual band predistortion linear power amplifier(PD LPA) using diplexer for digital cellular ($f_o$=880 MHz) and IMT-2000($f_o$=2,140 MHz) base stations. The diplexer is composed of low pass filter having defected ground structure(BGS) microstrip line and high pass filter having high-Q lumped capacitors and distributed elements. The proposed predistorter adopts a reflection type intermodulation signal generator with 3 dB hybrid coupler for good reflection characteristic. for a forward link one carrier CDMA IS-95A 1FA and WCDMA 1FA signal, the proposed dual band PD LPA shows the adjacent channel leakage ratio(ACLR) improvement about 10 dB and 9.36 dB for digital cellular and IMT-2000 band, respectively.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.20 no.8
• /
• pp.770-776
• /
• 2009

We propose and demonstrate an I/Q demodulator using four-port BPSK demodulator base on additive mixing and reflection-type phase shifter using hybrid technique. Previously, the conventional I/Q demodulator base on multiplicative or additive mixing method divides I/Q signal path from mixer to parallel-to-serial converter. In this paper, we propose new I/Q demodulator without dividing I/Q baseband signal path. The proposed schematic requires half size in implementation and half power consumption in baseband path compared with the conventional receiver. Also, the proposed receiver eliminates parallel-to-serial converter after data decoding. The proposed circuit has been successfully demodulated a QPSK signal with the L-band carrier frequency and 20 Mbps data rate.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2013.02a
• /
• pp.164-164
• /
• 2013

Among multicomponent nanostructures, hybrid nanocatalysts consisting of metal nanoparticle-semiconductor junctions offer an interesting platform to study the role of metal-oxide interfaces and hot electron flows in heterogeneous catalysis. In this study, we report that hot carriers generated upon photon absorption significantly impact the catalytic activity of CO oxidation. We found that Pt-CdSe-Pt nanodumbbells exhibited a higher turnover frequency by a factor of two during irradiation by light with energy higher than the bandgap of CdSe, while the turnover rate on bare Pt nanoparticles didn't depend on light irradiation. We also found that Pt nanoparticles deposited on a GaN substrate under light irradiation exhibit changes in catalytic activity of CO oxidation that depends on the type of doping of the GaN. We suppose that hot electrons are generated upon the absorption of photons by the semiconducting nanorods or substrates, whereafter the hot electrons are injected into the Pt nanoparticles, resulting in the change in catalytic activity. We discuss the possible mechanism for how hot carrier flows generated during light irradiation affect the catalytic activity of CO oxidation.