• The Korean Journal of Malacology
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• v.30 no.2
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• pp.155-163
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• 2014

Serpins are a group of proteins involved in the regulation of serine and other type of proteases, and have been identified in many kinds of organisms from invertebrates to vertebrates. Serpins are known to regulate the proteolytic cascades of the innate immune pathways in addition to their roles in blood coagulation, angiogenesis, fibrinolysis, inflammation and tumor suppression. In this study, we have isolated two partial serpin gene fragments from expressed sequence tags (ESTs) of Nesiohelix samarangae. Dotplot analysis indicates that they are of two different types, Ns-serpin type 1 and Ns-serpin type 2. Ns-serpin type 1 has 819 bp coding region (272 amino acids), whereas Ns-serpin type 2 has 555 bp coding region (185 amino acids). Molecular phylogenetic analysis shows that the identified serpins have high similarities to their counterparts in the California see slug, Aplysia californica. Yet, the precise biological and immunological roles of these Ns-serpins remain to be further investigated using RNA interference and other molecular techniques.

• Journal of Veterinary Clinics
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• v.24 no.4
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• pp.618-621
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• 2007

An 11-year-old, castrated male Yorkshire terrier dog was presented with multiple plaques on right inguinal region. Grade II mast cell tumor was diagnosed. The dog was treated with Vinblastine and prednisone(PDS) initially. Because of poor response of the dog, CCNU was added for more aggressive treatment. After 5 weeks treatment of with CCNU, vinblastine and PDS, the lesion was improved. Moderate leukopenia was shown after 4 cycles of chemotherapy. The chemotherapy was re-administered since the patient recovered from the leukopenia. Though the same protocol was applied, no improvement of the lesion was observed. Moreover, the general body condition of the dog became worse and was euthanized by the owner's request. Necropsy was not permitted. The survival time was 330 days after start of the chemotherapy.

• Journal of the Korean Solar Energy Society
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• v.32 no.6
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• pp.76-84
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• 2012

This study conducted experiments to measure air currents in an experimental building according to external conditions, types of induction ducts, and types of internal sockets by applying an external induction duct comprised of inducing openings and lines and induction units to the kitchen and bathroom vents at the rooftop of a super high-rise apartment building in order to help to improve the venting performance. The study also proposed the optimization of the external induction-style kitchen and bathroom vents capable of wind power generation. (1) As for air current distribution according to vent velocity changes, it increased the venting performance of the kitchen and bathroom by 1.0m/s at vent velocity of 2.0m/s or higher and allowed for wind power generation. (2)As for air current distribution according to external velocity changes, it increased the venting performance of the kitchen and bathroom by 1.2m/s at external velocity of 2.0m/s or higher and allowed for wind power generation. (3)As for air current distribution according to wind direction changes($0{\sim}180^{\circ}$), it was favorable for higher vent velocity when the angle between the external induction duct direction and prevailing wind direction was within ${\pm}30^{\circ}$. (4)As for air current distribution according to induction duct type, the[M1] type combining the inducing openings and lines with the induction units recorded the highest improvement effects in the kitchen and bathroom venting performance by increasing vent velocity by 46%. (5)As for air current distribution according to the changing types of internal sockets where the main ducts of the kitchen and bathroom are connected to the external induction ducts, the venturi tube type[Sv] increased vent velocity by 66% based on the smoothest external inflow.

• Journal of Biomedical Engineering Research
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• v.31 no.6
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• pp.434-437
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• 2010

For approval of medical devices manufactured or imported, submission of technical documents as well as the application form is required. The manufacturer (or importer) should properly identify the raw materials the applied product is made of and the manufacturing processes the product undergoes before it is shipped in the application form. In the technical documents, scientific data to evaluate the efficacy, safety, and quality of the applied product that has been described in the application form should be provided. Therefore, identifying the raw materials that were used for the parts of the applied product and describing the physical and chemical characteristics of the raw materials are quite important and essential in ensuring the efficacy, safety, and quality of the applied product. To describe the physical and chemical characteristics of the raw materials correctively, the applicant is required to have broad knowledge in the scientific fields such as chemical, polymer, metal, and ceramic science and engineering. But most of the applicant are not experts in these fields, so that the description in the application form often includes wrong and improper descriptions. Thus, we developed a guideline which explains the raw materials for medical devices, show the their examples. The purpose of this description guideline is to help the applicant properly completing the "Raw materials or constituents and their volumes" part in the application form.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.2
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• pp.219-230
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• 2014

There are many economical and industrial as well as social demands enabling smart management of railway vehicle including parts management by introducing RFID system in railway vehicle. In this paper, overseas researches and developments which use cases of RFID were investigated and analyzed. In this process, cases of various industries adopting RFID technology as well as cases of railway part were investigated. RFID system is used mainly for railway vehicle position detection and identification of vehicles in the field of railway. Also there are cases of application on traceability management of railway vehicle parts. The system in which RFID technology can be applied to railway parts management and traceability management is necessary for smart management of domestic railway vehicle.

• Korean Journal of Food Science and Technology
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• v.31 no.4
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• pp.971-976
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• 1999

Exo-polygalacturonase (EPG) from Rhizopus sp. was applied to the extraction of pectin from pear pomace because EPG produces pectin by solubilizing protopectin. The content of total galacturonic acid in water-alcohol insoluble pectin (WAIP) was determined as 34.6%. Pear pomace was solubilized by using EPG, with regarding reaction pH, temperature, time and ratio of enzyme to substrate in order to find optimum condition. While the yield by an acidic treatment was 6.2%, the maximum yield by an enzymatic treatment was 23.4% under the extraction condition of pH 7.8, $60^{\circ}C$, 36 hr and 1/10 of enzyme/substrate. At this condition, the purity and methoxyl content of enzyme-extracted pectin were, respectively, 34.7% and 0.7%, while those of acid-extracted pectin were, respectively, 71.1% and 5.0%. Meanwhile, the average molecular weight of pectin extracted by the enzymatic method was $2.5{\times}10^{3}$ while that of acid-solubilized pectin was $8.4{\times}10^{3}$.

• Journal of the Korean Solar Energy Society
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• v.32 no.3
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• pp.1-10
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• 2012

The purpose of this study was to promote the utilization of wind velocity of kitchen and bathroom exhaust ducts for wind power generation in high-rise apartments. The research content can be summarized as follows: 1) Nine high-rise apartments were examined for the installation of kitchen and bathroom exhaust ducts located in the pipe shaft (PS) section. After selecting simulation candidates, a simulation was performed with the STAR-CCM+ Ver 5.06 program. 2) Of nine high-rise apartments, seven had kitchen and bathroom exhaust ducts, whose cross section was in the range of $0.16m^2{\sim}0.4m^2$. The area ratio between the exhaust ducts and PS section (cross section of exhaust duct/area of PS section ${\times}$ 100) was on average 3.2%. 3) The simulation results were analyzed. As a result, the smaller cross section kitchen and bathroom exhaust ducts had, the more advantages there were for increasing exhaust wind velocity. If an out air inlet duct is installed to the old kitchen and bathroom exhaust ducts, it will increase exhaust wind velocity by 3.01~3.98m/s and contribute to the proper wind velocity level (3.0m/s). 4) When the simultaneous usage rate between the kitchen and bathroom exhaust fan increased from 20% to 60%, exhaust wind velocity increased. The "entire house holds" condition for exhaust fan operation provided more even exhaust wind velocity than the "some house holds" condition. 5) Exhaust wind velocity increased in the order of amplified (T-3), induced (T-2) and vertical (T-1) top of kitchen and bathroom exhaust ducts. Of them, the amplified type (T-3) was under the least influence of external wind velocity and thus the most proper for kitchen and bathroom exhaust duct tops.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.9 no.2
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• pp.66-78
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• 1999

The purpose of this study was to investigate the toxic effects of iso-butylalcohol on Sprague-Dawley (SD) rats which were treated 0, 333, 1,000 and 3,000 ppm for 6 hours a day, 5 days a week for 13 weeks by inhalation. Iso-butylalcohol did not induce any abnormal change in the viewpoint of clinical signs, feed consumption, ophthalmic test, urinalysis, hematology and blood biochemistry during and at the termination of the inhalation toxicity test. We did not find any abnormal findings in the gross and microscopic observations due to the inhalation of iso-butylalcohol. There was no alteration in relative organ weight owing to the inhalation of the iso-butylalcohol. In conclusion, concentration was 3,000 ppm in rats under the inhalation of 6 hours a day, 5 days a week for 13 week. Iso-butylalcohol did not show any change in the clinical signs, feed consumption, ophthalmic test, urinalysis, hematology and blood biochemistry, together with no alteration in the gross and pathological findings.

• Journal of the Korea institute for structural maintenance and inspection
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• v.22 no.6
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• pp.81-88
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• 2018

The present study evaluated the effective arrangement approach of transverse reinforcement in the jacket section for seismic strengthening of reinforced concrete columns. To simulate the full-scale columns, the section dimensions were determined as $450{\times}450mm$ for non-seismic existing columns and $750{\times}750mm$ for section enlargement strengthening columns. Over-lapped channel-shape bars and prefabricated bar units were proposed for closed-hoops in the jacket section, and conventional cross-ties anchored into existing columns and V-ties were considered for the supplementary ties. Test results showed that the axial capacity of the existing column and section enlargement columns with over-lapped channel-shape hoops was similar to the nominal strength calculated using ACI 318-14 procedure whereas the section enlargement column with prefabricated bar units possessed 1.25 times higher axial capacity than the nominal prediction. Furthermore, the axial ductility ratio of the section enlargement column with prefabricated bar unit was 139% higher than that of the existing column despite the potential size effect on ductility of concrete. Thus, it can be concluded that the developed prefabricated bar unit technique is practically useful for preventing the premature buckling of longitudinal reinforcement and confining core concrete in the section enlargement strengthening columns.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.3
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• pp.104-116
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• 2021

In order to reduce the social and economic costs due to the increase in dementia patients, which is a representative senile disease in an aging society, it will be important to prevent dementia and to detect and treat early in high-risk groups. This study reported the results of treatment for the elderly with high risk of dementia and depression who received Korean medicine (KM) treatment in 9 KM clinics. Medical charts were surveyed on 116 patients with high risk of dementia and depression who received KM treatment at 9 KM clinics in Gangseo-gu from September 1, 2020 to December 31, 2020. The majority of the patients were female(76.72%), the average age was 71.66±7.18 years old, and the average education level was 8.96±3.91 years. The average treatment period was 61.47±10.30 days, the average number of treatments was 15.38±1.06 times, and both acupuncture and herbal medicine were administered. After receiving KM treatment, cognitive assessment scores such as MMSE-DS and MoCA-K, depression-related GDSSF-K score, dementia knowledge, attitude, and preventive behavior, blood debilitation scale, and GQOL-D score were improved compared to before. There was no specific adverse reaction except that one patient with elevated AST and ALT levels was observed. This study showed improvement in cognitive function, depression, dementia-related scale, and quality of life in high-risk groups for dementia and depression over 60 years old who received KM treatment. More systematic and large-scale planned clinical studies will be needed.