• 제목/요약/키워드: Humanities and Social Sciences

검색결과 372건 처리시간 0.033초

Follow-up of Soluble Mesothelin-Related Protein Levels in Participants With Asbestos-Related Disorders

  • Park, Eun-Kee;Johnson, Anthony R.;Wilson, Donald;Thomas, Paul S.;Yates, Deborah H.
    • Safety and Health at Work
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    • 제11권4호
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    • pp.425-430
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    • 2020
  • Background: Asbestos exposure is associated with the development of the cancer malignant mesothelioma (MM). Measurement of soluble mesothelin-related protein (SMRP) has been suggested as a method for detection of MM in its early stages. We prospectively examined SMRP levels in participants with asbestos exposure who are a group at a high risk of development of MM. Methods: This study was a follow-up of our cohort of 322 asbestos-exposed participants. No further participants developed MM or malignancy over the study period. Mean follow-up time was 22.9 months. Results: Mean (standard deviation) SMRP levels at baseline and follow-up were 0.94 (0.79) and 0.91 (0.86) nmol/L (p = 0.1033), respectively. Mean SMRP levels of the healthy individuals exposed to asbestos at baseline was significantly lower than those of participants with asbestosis and pleural plaques alone; similar patterns were found on follow-up measurements. There was a statistically significant effect of age on serial SMRP measurements. Our study confirms higher levels in participants with nonmalignant asbestos-related disorders. Levels decreased in asbestos-related disorders other than asbestosis, where a small increase was observed. We did not detect any further cases of malignancy. Conclusion: Monitoring programs for early detection of MM need to take into account increased SMRP levels found in benign asbestos-related diseases.

한국어 /ㅛ/의 발음 양상 연구: 발음형 빈도와 음향적 특징을 중심으로 (Pronunciation of the Korean diphthong /jo/: Phonetic realizations and acoustic properties)

  • 이향원
    • 말소리와 음성과학
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    • 제15권1호
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    • pp.9-17
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    • 2023
  • 이 연구의 목적은 한국어 이중모음 /ㅛ/가 다양한 언어학적 환경에서 어떠한 발음 변이 양상을 보이는지 밝히는 것이다. 특히 음성적 변이와 분포 범위의 연관성에 주목하여 /ㅛ/의 발음 양상을 논의하였다. 서울코퍼스의 여성 화자 10명의 발화에서 나타난 /ㅛ/의 운율적 위치(단음절, 어절 초, 어절 중, 어절 말)와 어휘 부류(내용어, 기능어)를 분석하였다. 각 환경에서 /ㅛ/의 출현 빈도를 파악한 결과, 운율적 위치에 따라 어휘 부류와 발음형 실현이 달라지는 양상을 보였다. 음향 분석을 통해 기능어에서 나타나는 /ㅛ/에서는 음성적 약화가 빈번하게 일어나는 것을 확인하였다. 어휘 부류는 /ㅛ/의 평균적인 음가를 달라지게 하지는 않았지만 개별 토큰의 분포 양상에서는 차이가 발견되었다. 이를 통해 언어학적 환경이 모음의 음성적 분포 양상에 영향을 미친다는 것을 알 수 있었다.

Application of a Lateral Flow Immunoassay to Determine Ampicillin Residues in Muscle Tissue of Olive Flounder (Paralichthys olivaceus)

  • Cha, Chun Nam;Yu, Eun-Ah;Shin, Min Jung;Park, Eun Kee;Choi, Hyunju;Kim, Suk;Lee, Hu Jang
    • 한국식품위생안전성학회지
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    • 제28권3호
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    • pp.213-216
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    • 2013
  • Antibiotic Detection Kit (Combination I), a lateral flow immunoassay (LFIA) developed for the detection of antibiotic residues in milk, was utilized for the analysis of antibiotic residues in the muscle tissue of olive flounder. After 60-min treatment by dipping in water dosed with ampicillin (200-g/ton water), the residue depletion of ampicillin was investigated in 25 cultured olive flounder (Paralichthys olivaceus). Muscles of fish were sampled on the 1st, 2nd, 3rd, 4th and 5th day after drug treatment. The concentration of ampicillin in the muscle was determined by LFIA. The absorbance ratio of the sample to the control blank (Bs/Bo) was employed as an index to determine the muscle residues in olive flounder. To investigate the recovery rate, standard solutions were added to muscle samples to give final concentrations in the muscle of 4 and 8 ng/ml. The recovery rates of all spiked samples were > 96% of the spiked value. Ampicillin was detected in the muscle of fish treated with the drug until the 2nd day of the withdrawal period. The present study showed that the LFIA can be easily adopted to predict ampicillin residues in tissue of farmed fishes.

DACUM 기법을 통한 죽음교육프로그램 개발 분야의 직무분석 : 사회복지사를 중심으로 (Job Analysis by DACUM Method in the Field of Well Dying Education Model Development : focusing on the Social Worker)

  • 황혜정;김광환;김용하;이무식;심문숙
    • 한국산학기술학회논문지
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    • 제16권8호
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    • pp.5501-5507
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    • 2015
  • 이 연구는 사회복지사 대상 죽음교육 프로그램을 만들기 위해 DACUM 기법을 활용한 직무분석을 통해 사회복지사들이 현장에서 실제로 적용 가능한 의료적 시각과 인문학적 시각을 동시에 수용하는 융합된 죽음 교육 프로그램에 대한 사회복지사의 책무와 과업들을 규명하고자 하였다. 연구기간은 2015년 3월 2일부터 동년 3월 10일까지 직무분석을 위해 DACUM 위원 8명으로 구성된 보건의료 및 인문사회분야의 전문 교수진으로 구성되어 의료적, 인문학적 시각 및 사회적 시각으로 조사하였다. 연구결과, '상실과 애도' 책무에 대한 과업으로 '죽음의 수용과 이해'와 '상실 스트레스 치유 및 자살 예방 교육'이 중점이 되어야 함을 알 수 있었다. '죽음교육의 필요성' 책무에 대한 과업으로 '전통사회의 죽음과 현대사회의 죽음'이 '자신의 죽음과 관련된 문제의 이해'등으로 나타났다. 본 연구결과 인문학적 시각에 의한 죽음의 수용과 이해를 위한 힐링과 치유가 강조된 죽음교육 프로그램의 개발이 필요함을 시사해 주고 있다.

소방공무원에서 탄력성이 외상후스트레스 증상과 해리에 미치는 영향 : 우울의 매개 효과 (Depression as a Mediator of the Relationship Between Resilience and Posttraumatic Stress Symptoms and Dissociation in Firefighters)

  • 권태훈;현소연;정영기;임기영;노재성;강대용;하귀염;김남희
    • 정신신체의학
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    • 제24권1호
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    • pp.109-116
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    • 2016
  • 연구목적 본 연구는 소방공무원에서 탄력성이 외상후스트레스 증상 및 해리에 미치는 영향과 함께, 탄력성과 각 외상후스트레스 증상 및 해리의 관계에서 우울의 매개효과에 대해서 알아보고자 하였다. 방 법 총 115명의 소방공무원을 대상으로, 생활사건 체크리스트, 사건충격척도-개정판, 해리경험척도, 벡 우울척도, 코너-데이비슨 탄력성 척도를 시행하였다. 탄력성이 외상후스트레스 증상과 해리에 미치는 영향 및 우울의 매개효과를 확인하기 위해 구조방정식모형(Structural equation modeling)과 경로분석(path analysis)을 실시하였다. 결 과 탄력성이 높을수록 낮은 외상후스트레스 증상과 낮은 해리를 보였으며, 각 탄력성과 외상후스트레스 증상 및 해리의 관계는 우울이 완전 매개를 하는 것으로 나타났다. 즉, 탄력성이 외상후스트레스 증상 및 해리에 대해 직접적인 영향이 아닌 우울을 통해 간접적으로 각 증상을 감소시킴을 보여주었다. 결 론 본 연구는 소방공무원에서 외상후스트레스 증상 및 해리의 예방과 치료에 있어 탄력성 강화와 우울 증상 감소를 목표로 한 임상적 개입이 중요함을 시사한다.

Comparison of Biomechanical Characteristics for the Skill Level in Cycle Pedaling

  • Lee, Geun-Hyuk;Kim, Jai-Jeong;Kang, Sung-Sun;Hong, Ah-Reum;So, Jae-Moo
    • 한국운동역학회지
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    • 제26권1호
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    • pp.11-20
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    • 2016
  • Objective: This study aimed to compare biomechanical data between elite and beginner cyclists during cycle pedaling by performing a comparative analysis and to provide quantitative data for both pedaling performance enhancement and injury prevention. Methods: The subjects of this study included 5 elite cyclists (age: $18{\pm}0years$, body mass: $64.8{\pm}9.52kg$, height: $173.0{\pm}4.80cm$) and 5 amateur cyclists (age: $20{\pm}0years$, mass: $66.6{\pm}2.36kg$, height: $175.6{\pm}1.95cm$). The subjects pedaled on a stationary bicycle mounted on rollers of the same gear (front: 50 T and rear: 17 T = 2.94) and cadence of 90. The saddle height was adjusted to fit the body of each subject, and all the subjects wore shoes with cleats. In order to obtain kinematic data, 4 cameras (GR-HD1KR, JVC, Japan) were installed and set at 60 frames/sec. An electromyography (EMG) system (Telemyo 2400T, Noraxon, USA) was used to measure muscle activation. Eight sets of data from both the left and right lower extremities were obtained from 4 muscles (vastus medialis oblique [VMO], vastus lateralis oblique [VLO], and semitendinosus [Semitend], and lateral gastrocnemius [Gastro]) bilaterally by using a sampling frequency of 1,500 Hz. Five sets of events ($0^{\circ}$, $90^{\circ}$, $180^{\circ}$, $270^{\circ}$, and $360^{\circ}$) and 4 phases (P1, P2, P3, and P4) were set up for the data analysis. Imaging data were analyzed for kinematic factors by using the Kwon3D XP computer software (Visol, Korea). MyoResearch XP Master Edition (Noraxon) was used for filtering and processing EMG signals. Results: The angular velocity at $360^{\circ}$ from the feet was higher in the amateur cyclists, but accelerations at $90^{\circ}$ and $180^{\circ}$ were higher in the elite cyclists. The amateur cyclists had greater joint angles at $270^{\circ}$ from the ankle and wider knee joint distance at $0^{\circ}$, $180^{\circ}$, and $360^{\circ}$ than the elite cyclists. The EMG measurements showed significant differences between P2 and P4 from both the right VLO and Semitend. Conclusion: This study showed that lower body movements appeared to be different according to the level of cycle pedaling experience. This finding may be used to improve pedaling performance and prevent injuries among cyclists.

Kinematic Characteristics Based on Proficiency In Geoduepyeopchagi in Taekwondo Poomsae Koryo

  • So, Jae Moo;Kang, Sung-Sun;Hong, AhReum;Jung, Jong Min;Kim, Jai Jeong
    • 한국운동역학회지
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    • 제26권4호
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    • pp.343-351
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    • 2016
  • Objective: The purpose of this study was to help improve game performance and provide preliminary data to enhance the efficiency of the kick and stability of the support foot by comparing the kinematic characteristics of the repeated side kick (geodeupyeopchagi) in poomsaeKoryo between expert and non-expert groups. Method: The subjects were divided into 2 groups according to proficiency in Taekwondo, an expert group and a non-expert group (n = 7 in each group), to observe the repeated side-kick technique. Four video cameras were set at a speed of 60 frames/sec and exposure time of 1/500 sec to measure the kinematic factors of the 2 groups. The Kwon3D XPprogramas used to collect and analyze three-dimensional spatial coordinates. Ground reaction force data were obtained through a force plate with a 1.200-Hz frequency. An independent samplesttest was performed, and statistical significance was defined as .05. The SPSS 18.0 software was used to calculate the mean and standard deviation of the kinematic factors and to identify the difference between the experts and non-experts. Results: The angular displacement of the hip joint in both the expert and non-expert groups showed statistical significance on E1 and E4 of the left support foot and E5 of the right foot (p<.05). The angle displacement of the knee joint in both groups showed statistical significance on E4 of the left support foot, and E1 and E2 of the right foot (p<.05). The angular velocity of the lower leg in both groups showed no statistical significance on the left support foot but showed statistical significance on E2 and E6 of the right foot (p<.05). The angular velocity of the foot in both groups showed no statistical significance on the left support foot but showed statistical significance on E2 of the right foot (p<.05). The vertical ground reaction force in both groups showed statistical significance on E2 (p<.05). The center of pressure in all directions in both groups showed statistical significance (p<.5). Conclusion: While performing the repeated side kick (geodeupyeopchagi), the experts maintainedconsistency and stability of the angle of the support leg while the kick foot moved high and fast. On the other hand, the angle of the support foot of non-experts appeared inconsistent, and the kick foot was raised, relying on the support leg, resulting in unstable and inaccurate movement.

요중 AAMA에 의한 한국 성인 아크릴아마이드(AA)의 하루섭취량 추정 및 기여 식습관에 대한 분석 (Estimation of the Daily Human Intake of Acrylamide (AA) Based on Urinary N-acetyl-S-(2-carbamoylethyl)-cysteine (AAMA) and the Contribution of Dietary Habits in South Korean Adults)

  • LEE, Jin-Heon;LEE, Kee-Jae;KANG, Hee-Sook
    • 한국환경보건학회지
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    • 제42권4호
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    • pp.235-245
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    • 2016
  • Objectives: This study estimated the adult Korean daily intake of acrylamide (AA) and investigated its relationship with demographic, lifestyle and dietary habits by using urinary concentrations of N-acetyl-S-(2-carbamoylethyl)-cysteine (AAMA). Methods: Human data (n=1870) was collected in a nationwide cross-sectional biomonitoring program representing the population (18-69 years) residing in South Korea. Urinary AAMA was analyzed with a LC-MS/MS system. Daily intakes of AA were estimated using mass daily AAMA, which was calculated through urinary AAMA concentration and daily creatinine excretion. Statistical analysis was performed with SAS procedures for calculating geometric means, confidence intervals and the exponentiated beta coefficient of multiple linear regressions. Results: Daily intake of AA was estimated at $0.475{\mu}g/kg$ body weight (BW) per day (95% confidence interval (CI): 0.447-0.503). In the case of current smokers, AA intake was $0.957{\mu}g/kg$ BW per day (95% CI: 0.847-1.067), which was significantly higher than that of former smokers and never smoked (p<0.0001). The strong affecting factors were age (95% CI: 0.68-1.14; p=0.0180), education level (95% CI: 1.05-1.42; p=0.0163), body mass index (BMI) (95% CI: 1.00-1.82; p<0.0001), and smoking status (95% CI: 0.97-3.05; p<0.0001). Korean dietary habits increasing AA intake were coffee (p=0.0005), cup noodles (p=0.0010) and canned foods (p=0.0005). Meanwhile, foods decreasing AA intake were fresh fruit (p=0.0076), cooked beef (p=0.0335) and cooked pork (p=0.0147). Conclusion: The Korean daily intake of AA in adults was estimated to be similar with those found in developed countries. The factors increasing daily AA intake were coffee, cup noodles and canned foods, and decreasing factors were fresh fruit, cooked beef and cooked pork.

해밀토니안기법을 이용한 복수어업의 참조기 최적어획량 추정 (Estimating Optimal Harvesting Production of Yellow Croaker Caught by Multiple Fisheries Using Hamiltonian Method)

  • 남종오;심성현;권오민
    • 수산경영론집
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    • 제46권2호
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    • pp.59-74
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    • 2015
  • This study aims to estimate optimal harvesting production, fishing efforts, and stock levels of yellow croaker caught by the offshore Stow Net and the offshore Gill Net fisheries using the current value Hamiltonian method and the surplus production model. As analyzing processes, firstly, this study uses the Gavaris general linear model to estimate standardized fishing efforts of yellow croaker caught by the above multiple fisheries. Secondly, this study applies the Clarke Yoshimoto Pooley(CY&P) model among the various exponential growth models to estimate intrinsic growth rate(r), environmental carrying capacity(K), and catchability coefficient(q) of yellow croaker which inhabits in offshore area of Korea. Thirdly, the study determines optimal harvesting production, fishing efforts, and stock levels of yellow croaker using the current value Hamiltonian method which is including average landing price of yellow croaker, average unit cost of fishing efforts, and social discount rate based on standard of the Korean Development Institute. Finally, this study tries sensitivity analysis to understand changes in optimal harvesting production, fishing efforts, and stock levels of yellow croaker caused by changes in economic and biological parameters. As results drawn by the current value Hamiltonian model, the optimal harvesting production, fishing efforts, and stock levels of yellow croaker caught by the multiple fisheries were estimated as 19,173 ton, 101,644 horse power, and 146,144 ton respectively. In addition, as results of sensitivity analysis, firstly, if the social discount rate and the average landing price of yellow croaker continuously increase, the optimal harvesting production of yellow croaker increases at decreasing rate and then finally slightly decreases due to decreases in stock levels of yellow croaker. Secondly, if the average unit cost of fishing efforts continuously increases, the optimal fishing efforts of the multiple fisheries decreases, but the optimal stock level of yellow croaker increases. The optimal harvest starts climbing and then continuously decreases due to increases in the average unit cost. Thirdly, when the intrinsic growth rate of yellow croaker increases, the optimal harvest, fishing efforts, and stock level all continuously increase. In conclusion, this study suggests that the optimal harvesting production and fishing efforts were much less than actual harvesting production(35,279 ton) and estimated standardized fishing efforts(175,512 horse power) in 2013. This result implies that yellow croaker has been overfished due to excessive fishing efforts. Efficient management and conservative policy on stock of yellow croaker need to be urgently implemented.

봉사학습 기반의 대학 피부미용 교양수업이 삶의 질, 자기효능감에 미치는 영향 (The Effect of General Eduction Class on Skin Care Based on Service Learning on Quality of Life and Self-Efficacy)

  • 박정연;심현애
    • 한국엔터테인먼트산업학회논문지
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    • 제13권7호
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    • pp.479-485
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    • 2019
  • 본 연구는 봉사학습 기반의 피부미용 교양수업 운영에 대한 학습 효과를 분석하여 도출하고, 이를 바탕으로 대학 교양교육의 목적과 가치에 대해 성찰하여 뷰티봉사학습의 활성화를 위한 기초자료로 제공하고자 한다. 그 결과 연구대상으로 최종 선정된 30명 중 여학생이 24명(80.0%)이었고, 학년은 3학년 학생이 16명(53.3%)으로 가장 많았다. 전공은 인문사회계열 12명(40.0%), 종교는 21명(70.0%)이 무교로 각각 가장 높게 조사되었다. 봉사학습이 자기효능감과 삶의 질에 미치는 영향을 알아보기 위하여 자기효능감과 삶의 질의 사전- 사후 변화를 분석한 결과 통계적으로 유의미한 차이가 나타나 봉사학습이 자기효능감과 삶의 질 향상에 효과가 있는 것으로 확인할 수 있었다. 봉사학습에 대한 만족도는 평균 4.12점으로 대체적으로 봉사학습에 대해 만족한 것으로 파악되었으며, 봉사학습 지속 의도는 평균 3.99점으로 나타나 지속적인 봉사학습 의향이 있는 것으로 조사되었다. 또한 연구대상자의 성별, 학년, 전공, 종교 등의 특성에 따라 봉사학습의 만족도 및 지속의도에 차이가 없는 것으로 조사되었다. 이상의 결과 봉사학습 기반의 피부미용 교양교육은 학습자들의 자기효능감과 삶의 질 향상에 긍정적 영향을 미치는 것을 알 수 있었다. 이는 학습자들이 대학교육을 통해 공동체 의식 함양과 사회적 자아로서의 책임감을 강화하는 데 도움이 될 것이라 생각된다.