• The Korean Journal of Food And Nutrition
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• v.26 no.3
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• pp.366-374
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• 2013

Anti-diabetic activities of cultured mycelia from Ganoderma applanatum are being evaluated in this study. The OGTT and 4-weeks of repeated oral efficacy tests are conducted in mice at the doses of 0 (vehicle treatment), 25, 75 and 225 mg/kg/day, respectively. In human study, the test article was administered orally every day for 8-week at a dose of 1,500 mg/kg, tid and placebo group. The blood glucose levels (BGL) at 0.5 hour after treatment are significant decreased in all treatment groups of OGTT test. In the 4-week test, BGL of 75 and 225 mg/kg/day group is continuously decreased during all treatment periods and the BGL of 25 mg/kg/day group show decreasing trends at the final week, the pancreas weight of all treatment groups are being increased, and the Langerhans-islet numbers were increased at all treatment groups with a dose-response manner. There are no test article-related abnormal signs and the fasted blood glucose (FBG), postprandial blood glucose (PPG) and HbA1c are decreased significantly after 8-week treatments. These results that the cultured mycelia from Ganoderma applanatum could decrease BGL by protecting the degeneration of Langerhans islets.

• Korean Journal of Human Ecology
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• v.1 no.1
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• pp.103-112
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• 1998

Cotton fabric was treated with chitosan by pad-dry(-cure) method to impart antimicrobial properties. Four chitosans of different degree of deacetylation (DAC: 65~95%) with similar molecular weight(MW: ca. 50, 000) and one chitosan oligomer(MW 1, 800, DAC 86%) were used. In order to improve the durability to laundering of antimicrobial activity for the fabrics treated with chitosan oligomer, crosslinker or binder was included in the finishing formulation. Antimicrobial activity against Staphylococcus aureus and Proteus vulgaris was evaluated by the Shake Flask Method. The treated fabrics were laundered up to 20 times according to AATCC Test Method 60-1986 or JIS 0217-104 and antimicrobial activity of the laundered fabrics was evaluated. The antimicrobial activity was increased with the increase of concentration and degree of deacetylation of chitosan. And the cured fabrics showed better durability to laundering than the not-cured fabrics according to AATCC Test Method 60-1986. Crosslinker and binder decreased antimicrobial according of the fabrics treated with chitosan oligomer and were not effective to improve the durability to laundering according to JIS 0217-104. (Korean J Human Ecology 1(1) : 103~112, 1998)

• Journal of Microbiology and Biotechnology
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• v.22 no.6
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• pp.838-848
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• 2012

Orally administered herbal glycosides are metabolized to their hydrophobic compounds by intestinal microflora in the intestine of animals and human, not liver enzymes, and absorbed from the intestine to the blood. Of these metabolites, some, such as quercetin and kaempherol, are mutagenic. The fecal bacterial enzyme fraction (fecalase) of human or animals has been used for measuring the mutagenicity of dietary glycosides. However, the fecalase activity between individuals is significantly different and its preparation is laborious and odious. Therefore, we developed a fecal microbial enzyme mix (FM) usable in the Ames test to remediate the fluctuated reaction system activating natural glycosides to mutagens. We selected, cultured, and mixed 4 bacteria highly producing glycosidase activities based on a cell-free extract of feces (fecalase) from 100 healthy Korean volunteers. When the mutagenicities of rutin and methanol extract of the flos of Sophora japonica L. (SFME), of which the major constituent is rutin, towards Salmonella typhimurium strains TA 98, 100, 102, 1,535, and 1,537 were tested using FM and/or S9 mix, these agents were potently mutagenic. These mutagenicities using FM were not significantly different compared with those using Korean fecalase. SFME and rutin were potently mutagenic in the test when these were treated with fecalase or FM in the presence of S9 mix, followed by those treated with S9 mix alone and those with fecalase or FM. Freeze-dried FM was more stable in storage than fecalase. Based on these findings, FM could be usable instead of human fecalase in the Ames test.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.156-163
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• 2019

In this paper, we present the process of developing an automatic carrying and arming system for testing ammunition. When carrying out shooting tests at a domestic rifle range, most of the ammunition operations are carried out by human manpower The series of test processes, such as transporting, arming and firing of heavy munitions, is repeated by employing human. If the ammunition is loaded via manpower, then problems can occur such as loss of reliability of test results, musculoskeletal disorders of humans and also safety accidents can occur. To address these problems, an automated system was developed for the transport and operation of ammunition. This paper covers the design, manufacture and operation of the developed system. In addition, this study validated the effectiveness of the system as compared to the human operation. Our results show that the developed system can be easily adapted to testing ammunition at a domestic rifle range.

• Korean Journal of Culture and Social Issue
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• v.16 no.3
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• pp.267-287
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• 2010

This study aimed to improve the Traffic Accident Management System's validity and reliability, so the system could help classify and judge the human factors that correlate with traffic accidents. We took traffic accident research and analysis systems of United States and United Kingdom and certain related, former studies into account in building our test system. Next, we used the test system's criteria to re-analyze 502 Gyeonggi province accident records from 2008. We compared the results to existing systems' results to verify the test system's validity and reliability. These results indicated the necessity of removing some uncertain items from the existing systems and adding in some new items from the test system. This should help improve understanding of what happens at traffic accident scenes and of the sources of drivers' abnormal, reckless behavior. We introduce suggestions for improving the Traffic Accident Management System and research concepts for further studies.

• KEPCO Journal on Electric Power and Energy
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• v.5 no.4
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• pp.249-256
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• 2019

A full-scale test line was established to verify the electrical environmental interferences caused by the HVDC ±500 kV Double Bipole overhead transmission line with metallic return conductor, which is scheduled for construction in Korea and the fullscale test was conducted for one year. And through the human perception test of the DC electric-field under the HVDC Double Bipole line, the threshold value at which the human detects DC electric field was investigated to verify the validity of the design guide for the HVDC ±500 kV Double Bipole overhead transmission line. The polarity configuration of the HVDC ±500 kV Double Bipole test line was arranged diagonally with the same polarity in terms of the electrical environment disturbance and operation. The test line utilized the 6-bundle arrangement to prevent the corona discharge taking into account the domestic social acceptability. The test results show that the HVDC ±500 kV Double Bipole transmission line generated very little corona discharge from the conductors. Therefore, both DC electric field and ion current density met the domestic design guide for DC overhead transmission lines. Also, the human perception test of DC electric fields under the test line showed that 70% of participants did not recognize the DC electric field even when exposed to 23 kV/m.

• Fashion & Textile Research Journal
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• v.18 no.5
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• pp.695-707
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• 2016

This study presents quantitative evaluation standards for the shape fitness test, conducted in the process of the slacks fit test. This study aims to quantify appearance sensory test of slacks for the objectification of qualitative evaluation methods in existing shape fitness tests. The subjects were women of standard body type between the ages of 18 and 24. Slacks differing in their ease in waist girth, hip girth, crotch length and knee length were designed to test their shape fitness. The gap volume distribution between the body and slack, angle of the baseline by body part, and ratio of total thickness from the sideline using 3D human body scan data (which reflect the results of the appearance sensory test) were presented as quantitative evaluation standards. There were less wrinkles in the wrinkle/overstretch and ease categories of the appearance sensory test; in addition, ease was adequate and small enough to comfortably perform basic human activities in the standing upright posture. The gap volume distribution analysis between body and slacks showed that curves increased in the slacks surface along with an increase of ease in slacks and suggested that wrinkles also increased. In the baseline's horizontal categories in terms of a $0^{\circ}$ horizontal angle, the range of angles were evaluated as adequate by the clothing expert group. The total thickness ratio of 0.5:0.5 divides into the sideline from the baseline.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.4
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• pp.516-523
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• 2015

This study investigated the antimutagenic and anticancer effects of Platycodon grandiflorum extract (PGE) and its fractions against carcinogenic N-nitrosodimethylamine (NDMA) and genotoxicity. The Ames Salmonella mutagenicity test employing histidine mutants of Salmonella Typhimurium TA98 and TA100 was used to examine the mutagenicity of PGE and its fractions. Bacterial reversion assay with S. Typhimurium TA98 and TA100 did not show a significantly increased number of revertant colonies. The same test was used to examine the ability of PGE and its fractions to prevent acquisition of N-methyl-N'-nitro-N-nitrosoguanidine- and 4-introquino-line-1-oxide-induced mutations. PGE and its fractions inhibited mutagenesis in a dose-dependent manner. Among the fractions, ethyl acetate fraction from PGE (PGEA) exhibited a higher antimutagenic effect than other fractions. PGE and its fractions suppressed the growth of cancer cell lines, including human cervical adenocarcinoma, human hepatocellular carcinoma, human breast adenocarcinoma, human lung carcinoma, and transformed primary human embryonic kidney cells. In addition, we evaluated the antitumor activity of PGEA and its fractions in sacorma-180 solid tumor-bearing mice. In vivo anticancer activity results showed that PGE and its fractions could more effectively suppress tumor growth than the control. PGEA showed higher in vitro and in vivo anticancer effects than PGE and other fractions, and PGEA inhibited NDMA formation. Thus, we showed that PGEA has antimutagenic and anticancer activities, making it a candidate anticancer material under these experimental conditions.

• Journal of Families and Better Life
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• v.26 no.1
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• pp.107-120
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• 2008

The purpose of this study was to analyze the effects of human resource development on the job satisfaction and wage among employed workers. A sample of 3,578 employed workers was selected from Korea Labor Panel Data. For data analysis, t-test and multiple regression were used. The major findings were as follows: First, the employed workers who had experiences of human resource development had more certificates of job-related qualification, more employed in government-invested organization or foreign company regularly than the counterpart. Second, the employed workers' wage was affected by gender, age, educational attainment, as well as whether they had experiences of human resource development. Third, the factors that influence employed workers' job satisfaction were gender, age, educational attainment, job regularity, having certificate of job-related qualification or not, and having experiences of human resource development or not. From the findings, it can be concluded that the employed workers' wage and job satisfaction were improved by the human resource development.

• Korean Journal of Community Nutrition
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• v.3 no.2
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• pp.281-291
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• 1998

Job analysis was done by the method of interview and survey to find out the human attributes needed for dietitans' job performance. The knowledge, skills, abilities and other characteristics including personality were major items in the questionnaire. The questionnaire was distributed to 340 schools and hospital dietitians. Among these, 201 were compeletely filled out, returned and statistically analyzed according to the frequency scale and importance scale respectively. The results were as follows : 1) The age, education, job experience and monthly pay of hospital dietitians were higher than those of school dietitians. This was partly due to the reflection of short chronicle of school foodservice. 2) The most important human attributes for rwo groups were commonly shown as sincere and faithful personality, good human relationship and responsibility for business outcome. 3) Computer skill and menuplanning ability were human attributes of the most frequently used by school dietitians, whereas knowledge of diet therapy, clinical nutrition, and pathology of disease were frequently used by hospital dietitians. 4) The correlation coefficients between two groups were as follows : Spearman's rho value of personality, skills and abilities, and knowledge were 0.806, -0.432,-0.203 respectively, according to the importance scale. 5) An overall view from t test between two groups, various human attributes, especially knowledge were more frequently used by hospital dietitians.