• Title/Summary/Keyword: Human Dimension

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Identification of matrix metalloproteinases secreted by human hepatocarcinoma HepG2 cells

  • Lee, Young Jae;Kim, Keun Cheon;Lim, Jeong Mook;Lee, Seung Tae
    • Journal of Animal Reproduction and Biotechnology
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    • v.37 no.1
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    • pp.62-66
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    • 2022
  • To date, the development of anticancer drugs has been conducted using two-dimensional (2D) cell culture systems. However, since cancer cells in the body are generated and developed in three-dimensional (3D) microenvironments, the use of 2D anticancer drug screening can make it difficult to accurately evaluate the anticancer effects of drug candidates. Therefore, as a step towards developing a cancer cell-friendly 3D microenvironment based on a combination of vinylsulfone-functionalized polyethylene glycol (PEG-VS) with dicysteine-containing crosslinker peptides with an intervening matrix metalloproteinase (MMP)-specific cleavage site, the types of MMPs secreted from human hepatocarcinoma HepG2 cells, a representative cancer cell, were analyzed transcriptionally and translationally. MMP3 was confirmed to be the most highly expressed protease secreted by HepG2 cells. This knowledge will be important in the design of a crosslinker necessary for the construction of PEG-based hydrogels customized for the 3D culture of HepG2 cells.

A Study on the Analysis of Aesthetic Shape Shown on the Modern Flat Patterned Clothing (현대 평면의에 나타난 형태미에 관한 연구)

  • Kwen, Jin
    • Journal of the Korean Society of Costume
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    • v.56 no.7 s.107
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    • pp.115-125
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    • 2006
  • The study on plane composition in clothing was focused mainly on woven wear earlier but its application has been reaching the knit wear. This study is confined to the utilization with geometrical linear pattern in the modern apparel. The work here intends to grasp the plane structure found in both woven wear and knit wear and, in particular, to understand the aesthetics of fashion. The modern flat patterned clothing has been affected by the oriental style or postmodernism in view of social and cultural aspect while its fabric material and expression method shows the diversity in terms of industrial and technical aspect. It can be characterized as several outstanding patterns: the geometrical pattern in structure, the linear pattern with seam line and 2-dimensional plane pattern without seam line, and the flexible silhouette integrated into one single shape with human body unlike the traditional apparel The aesthetics of fashion in modern flat patterned clothing can be divided into such category as the organically spatial change, the re-creation of tradition and the non-format framework. The organically spatial change shows the geometrical formation in clothes due to change in dimension, where the organically changing uniformity and generosity appears as the dimension progresses. The timeless without any difference of up and down, left and right, and inside and outside and the discontinuity due to limitless spatial change are also imbedded. The re-creation of tradition tells the reshaped spirits of old tradition by integrating and modifying the hereditary features in the old customed clothing into modern clothing. The modern flat patterned clothing implies the contemporaneousness or the frame through which the old and modern cultures may be shared and indicates the re-creation of the past and uniformity. The non-format framework contains the uncertainty in meaning and it doesn't have any certain standards. As both the apparel and the human body with this style aim at the open space, the numerous contingencies are realized.

The Influence of After-Sales Service Quality on Customer Satisfaction and Loyalty in Mobile Phone (휴대폰 애프터서비스 품질이 고객만족과 고객충성도에 미치는 영향)

  • Lee, Jae jun;Ryu, Ji-Hyun;Lee, Sae-Jae;Oh, Hyun-Seung;Cho, Jin-Hyung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.4
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    • pp.87-95
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    • 2017
  • This study aims to configure what dimensions make up for smart phone after service quality, and how this service quality affects customer satisfaction and customer loyalty. Smart phone market is a market of the device leading the digital convergence as well as positioning itself as one of the national growth driving industry. To survive in this matured market, companies should have to respond actively to radical changes and customers needs in the so-called Smart Revolution environment. Lately, however, the smart phone market is prospected to move from growth phase to mature phase by the scholars. In order to proactively respond to the change in such market condition, companies need to provide absolute advantage in customer loyalty over their competitors by revolutionizing the after-sales service quality. Qualified A/S will lead to service satisfaction and achieve customer loyalty. The empirical analysis results obtained through A/S quality are as follows : First, human quality (attitude, expertise, problem-solvability), environment quality (handling agility, convenience, comfort), service policy quality (quality guarantee, additional service operation) are dimensions that make up for A/S quality. Second, A/S quality dimension showed a significant positive influence on service satisfaction and A/S satisfaction showed a positive influence on customer loyalty as well. Based on this empirical study, we propose some implications for A/S quality improvement. First, human quality dimension has relatively higher influence on A/S satisfaction in case of free A/S, so companies need to solve the product problem completely when consumer's first visit by continual employee education. Second, in case of paid A/S, the service policy quality-especially A/S Warranty period- has higher influence on A/S satisfaction.

Multiple Dimension User Motion Detection System base on Wireless Sensors (무선센서 기반 다차원 사용자 움직임 탐지 시스템)

  • Kim, Jeong-Rae;Jeong, In-Bum
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.3
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    • pp.700-712
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    • 2011
  • Due to recently advanced electrical devices, human can access computer network regardless of working location or time restriction. However, currently widely used mouse, joystick, and trackball input system are not easy to carry and they bound user hands exclusively within working space. Those make user inconvenient in Ubiquitous environments.. In this paper, we propose multiple dimension human motion detection system based on wireless sensor networks. It is a portable input device and provides easy installation process and unbinds user hands during input processing stages. Our implemented system is comprised of three components. One is input unit that senses user motions and transmits collected data to receiver. Second is receiver that conveys the received data to application, which runs on server computer. Third is application that performs command operations according to received data. Experiments shows that proposed system accurately detect the characteristics of user arm motions and fully support corresponding input requests.

3D Volumetric Capture-based Dynamic Face Production for Hyper-Realistic Metahuman (극사실적 메타휴먼을 위한 3D 볼류메트릭 캡쳐 기반의 동적 페이스 제작)

  • Oh, Moon-Seok;Han, Gyu-Hoon;Seo, Young-Ho
    • Journal of Broadcast Engineering
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    • v.27 no.5
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    • pp.751-761
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    • 2022
  • With the development of digital graphics technology, the metaverse has become a significant trend in the content market. The demand for technology that generates high-quality 3D (dimension) models is rapidly increasing. Accordingly, various technical attempts are being made to create high-quality 3D virtual humans represented by digital humans. 3D volumetric capture is spotlighted as a technology that can create a 3D manikin faster and more precisely than the existing 3D model creation method. In this study, we try to analyze 3D high-precision facial production technology based on practical cases of the difficulties in content production and technologies applied in volumetric 3D and 4D model creation. Based on the actual model implementation case through 3D volumetric capture, we considered techniques for 3D virtual human face production and producted a new metahuman using a graphics pipeline for an efficient human facial generation.

Impact Analysis of nonverbal multimodals for recognition of emotion expressed virtual humans (가상 인간의 감정 표현 인식을 위한 비언어적 다중모달 영향 분석)

  • Kim, Jin Ok
    • Journal of Internet Computing and Services
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    • v.13 no.5
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    • pp.9-19
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    • 2012
  • Virtual human used as HCI in digital contents expresses his various emotions across modalities like facial expression and body posture. However, few studies considered combinations of such nonverbal multimodal in emotion perception. Computational engine models have to consider how a combination of nonverbal modal like facial expression and body posture will be perceived by users to implement emotional virtual human, This paper proposes the impacts of nonverbal multimodal in design of emotion expressed virtual human. First, the relative impacts are analysed between different modals by exploring emotion recognition of modalities for virtual human. Then, experiment evaluates the contribution of the facial and postural congruent expressions to recognize basic emotion categories, as well as the valence and activation dimensions. Measurements are carried out to the impact of incongruent expressions of multimodal on the recognition of superposed emotions which are known to be frequent in everyday life. Experimental results show that the congruence of facial and postural expression of virtual human facilitates perception of emotion categories and categorical recognition is influenced by the facial expression modality, furthermore, postural modality are preferred to establish a judgement about level of activation dimension. These results will be used to implementation of animation engine system and behavior syncronization for emotion expressed virtual human.

Fractal analysis of mandibular trabecular bone: optimal tile sizes for the tile counting method

  • Huh, Kyung-Hoe;Baik, Jee-Seon;Yi, Won-Jin;Heo, Min-Suk;Lee, Sam-Sun;Choi, Soon-Chul;Lee, Sun-Bok;Lee, Seung-Pyo
    • Imaging Science in Dentistry
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    • v.41 no.2
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    • pp.71-78
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    • 2011
  • Purpose : This study was performed to determine the optimal tile size for the fractal dimension of the mandibular trabecular bone using a tile counting method. Materials and Methods : Digital intraoral radiographic images were obtained at the mandibular angle, molar, premolar, and incisor regions of 29 human dry mandibles. After preprocessing, the parameters representing morphometric characteristics of the trabecular bone were calculated. The fractal dimensions of the processed images were analyzed in various tile sizes by the tile counting method. Results : The optimal range of tile size was 0.132 mm to 0.396 mm for the fractal dimension using the tile counting method. The sizes were closely related to the morphometric parameters. Conclusion : The fractal dimension of mandibular trabecular bone, as calculated with the tile counting method, can be best characterized with a range of tile sizes from 0.132 to 0.396 mm.

A Study of Relationship of Webmedia addictive Experience and Self-identity (웹미디어의 중독적 이용 경험과 개인의 자아정체성에 관한 연구)

  • Kim, Sung-Byuk
    • Korean journal of communication and information
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    • v.28
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    • pp.7-41
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    • 2005
  • This study emphasized the self-examination to using webmedia. Proliferation of media-mediated experience cause the reduce and infringe of human experience, and It is suggested to problem to negative operation for Self-identity. Expecially, A tendency of addictive using of Webmedia produce the serious anxiety. Based on this discussion, the relationship of web-media addictive experiences and Self-identity has been studied. There are 9 groups of panels who are divided by using degree of web media experience, the quantitative dimension and addictive involvement, the qualitative dimension. As a result high significance was suggested between the level of web-media addictive experience and Self-identity. Expecially, highly web media experienced group has less Self-identity than low web-media experience group. therefore, Concerns on Web-media mediated experiences were demonstrated. According to the results, in terms of web-media experiences, addictive involvement level affects more meaningfully to the Self-identity than quantitative dimension approach.

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Charaeteristics of Women′s Fashion in the 20th Century Based on the Threefold Structure of Semiotics (기호의 삼분구조에 의한 20세기 여성 패션의 특성 분석)

  • Kim Eun-Kyoung;Kim Young-In
    • Journal of the Korean Society of Costume
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    • v.54 no.7
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    • pp.41-54
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    • 2004
  • This study purposed to apply function form content, the three concepts that have been discussed by many philosophers since ancient times, to fashion design. Specific research goals are : first, to define fashion design based on the three concepts : and second, to examine how each of the three concepts function-oriented, form-oriented and content-oriented design have been expressed in women's fashion in the $20^{th} century. For these purposes. the author considered Morris' semiotics, which is the theoretical background of the three concepts, reviewed previous researches in design area, and applied the findings to fashion design. According to the result of applying the threefold structure of semiotics. which is the theoretical background of the three concepts, the pragmatic dimension of fashion design comprehends all functional rules related to the use of dress such as body motion and protection, health and safety. air flow and durability, and its syntactic dimension comprehend all the formal elements of visual design such as the structure, shape, line, color and material of dress. The semantic dimension of fashion design includes the symbolic meanings of dress expressed by emotion, sentiment and images. The three dimensions exist interdependently with one another. According to the result of considering the characteristics of the three concepts in the scope of women's fashion in the $20^{th} century. function-oriented design is characterized by practicality and simplicity, and has been expressed as the fashion of functionalism in the 1920s, that of minimalism in the 1960s, and the basic style from 1970s to 1980s, 1990s and the present. Form-oriented design has pursued aestheticism, putting stress upon form, and has been expressed with organic shapes imitating patterns found in nature in the 1950s and with optical art fashion in the 1960s. Content-oriented design attaches importance to transmission of delicate meanings related to the mental world of human beings, and is represented with symbolic forms. Such a characteristic has been expressed in fashion in the early 20th century influenced by surrealism and, with various types of design breaking established forms as well as metaphors and humors that characterize design in the late 20th century.

Effect and Value of Custom-made Mouthguard in Athletic Performance (맞춤형 마우스가드의 효능과 실제)

  • Lee, sungbok Richard
    • The Journal of the Korean dental association
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    • v.53 no.9
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    • pp.602-609
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    • 2015
  • The aim of this document is to evaluate the effect of bite balance on physical fitness and motor capacity to determine the importance of the occlusal stability as a possible action mechanism of occlusal appliance including mouthguards on physical performances. We all remember that day when the prominent athlete was in the news wearing a mouthguard to improve human athletic performance. I once had investigated the determinants of athletic performance in all sorts of sports. Most of the studies had overinterpretation of results and lack of evidence to support the information. However, I discovered great expectations for new possibility in this field and settled for a more academic approach to this intriguing subject. The followings are some examples of the subject 1. Archers who wore occlusal appliances to increase the vertical dimension of occlusion by 2~3mm increased their ability to focus and to maintain good sense of balance. Their accuracy rate has been improved. The appliance was made of acrylic resin (a type of plastic). 2. Canoe players who wore occlusal appliances to increase the vertical dimension of occlusion by 5mm surpassed longtime competitor and won the race with 10 seconds gap. 3. A cycle rider who wore an occlusal appliance to treat his malocclusion surpassed his old record from 10.8 seconds to 10.3 seconds. His muscle reflexes (anaerobic exercise) and endurance (aerobic exercise) has been enhanced. 4. Occlusal appliances had a good effect on athletic performance in most sports such as swimming, diving, and weightlifting. As for the clenching on dentition, people clench their teeth when they push their physical and mental limits during sports activities. Clenching can be induced by physical exertion when maximum muscle strength is retained and this is similarly found in different types of exercises. In addition, restraint of respiratory function is observed. Therefore, creating a occlusal balance with occlusal appliance or mouthguard promoted a favorable influence when an athlete clenches.