• Journal of Preventive Medicine and Public Health
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• v.57 no.3
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• pp.252-259
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• 2024

Objectives: This study investigated factors associated with the retention of people living with human immunodeficiency virus (HIV) on antiretroviral therapy (ART) during the first 3 years of treatment. Methods: A retrospective study using electronic health records was conducted at a tertiary hospital in Jakarta, Indonesia. Adult HIV-positive patients who started ART from 2010 until 2020 were included. A binary logistic regression model was used to identify factors associated with ART retention in the first 3 years. Results: In total, 535 respondents were included in the analysis. The ART retention rates for the first, second, and third years were 83.7%, 79.1%, and 77.2%, respectively. The multivariate analysis revealed a negative association between CD4 count when starting ART and retention. Patients with CD4 counts >200 cells/mL were 0.65 times less likely to have good retention than those with CD4 counts ≤200 cells/mL. The year of starting ART was also significantly associated with retention. Patients who started ART in 2010-2013 or 2014-2016 were less likely to have good retention than those who started ART in 2017-2020, with adjusted odds ratios of 0.52 and 0.40, respectively. Patients who received efavirenz-based therapy were 1.69 times more likely to have good retention than those who received nevirapine (95% confidence interval, 1.05 to 2.72). Conclusions: Our study revealed a decline in ART retention in the third year. The CD4 count, year of enrollment, and an efavirenz-based regimen were significantly associated with retention. Patient engagement has long been a priority in HIV programs, with interventions being implemented to address this issue.

• Clinical and Experimental Reproductive Medicine
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• v.23 no.1
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• pp.103-108
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• 1996

Through the previous studies(I,II), it was observed that human follicular fluid(HFF) was more effective than human fetal cord serum(HFCS) on promoting meiotic resumption of oocytes and improving embryonic development of mouse in vitro. On the basis of these results, we have gradually exchanged HFCS with HFF as protein supplement in human ART. This study was performed to investigate the efficiency of HFF on improving the pregnancy rate in ART. Oocytes were retrieved transvaginally from patients treated with pituitary suppression with GnRH-agonist and ovarian stimulation with human menopausal gonadotro-pin(HMG) and pure follicle stimulating hormone(FSH). Aspirated oocytes were rinsed and cultured in TCM-199 containing HFF, and the concentrations of HFF were adjusted to 10, 20, and 30% according to the use for insemination, embryo growth and embryo transfer, respectively. As possible as, we tried to do embryo transfer into fallopian tube to mimic the coincidence of the cell stage with the place of sojourn in vivo, so we performed various ART programs(IVF & ET; in vitro fertilization, ZIFT; zygote intra fallopian-tube transfer, ZIFT & ET) according to the tubal conditions of patients. On the while, intra cytoplasmic sperm injection(ICSI) was used to assist IVF of the patients who had shown poor standard IVF results by immunological or severe male factor. Of the 255 cycles of ART programs using HFF as protein supplement, 118 cycles were turn out to be succeeded in pregnancy(46.2%, per cycle, p<0.05), while 21 pregnancies were achieved in the 69 cycles using HFCS(30.4%). The 255 cycles using HFF were subdivided into cycles with the type of ART programs, and each pregnancy rate of the ART programs were 44.7% (IVF & ET, 76/170 cycles), 53.4%(ZIFT, 31/58 cycles) and 40.7% (ZIFT & ET, 11/27 cycles), respectively. In the 61 ICSI cycles using HFF, 28 cycles succeed in pregnancy(45.9%), while 7 pregnancies were obtained in the 17 ICSI cycles using HFCS. Also the ongoing pregnancy rate in the group using HFF(78.8%, 93/118 cycles) was higher than that in the group using HFCS(61.9%). Therefore, we found that the use of HFF as protein supplement was more suitable and effective than the use of HFCS to improve the pregnancy rate in ART.

• 대한생식의학회:학술대회논문집
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• 2003.12a
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• pp.123-124
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• 2003

• Korean Journal of Human Ecology
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• v.16 no.5
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• pp.909-920
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• 2007

The purpose of this study was to investigate the effects of group art therapy on increasing Self-Supporting Recipients Women's well-being and on decreasing their depression. This group art therapy program model was developed based on problem -solving theory and art therapy theory. This program was consisted of 15 session with 9 women focused on self understanding through perception of multiple problems of self-supporting recipients women. Dependent variables were index of well-being and depression. The results were as follows. This program showed the significant differences between post-test and pre-test scores in the scale of well-being and depression. Also that showed the significant difference between follow-up and post test score in the scales of well-being, but there is no difference between follow-up and post test. In Conclusion, group art therapy employed for this study have significant effects of increasing well-being and decreasing depression.

• Korean Journal of Human Ecology
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• v.20 no.5
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• pp.967-981
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• 2011

This study aims to research the effects of group art therapy program on the self-esteem and peer relationships of children in low-income and single-parent families. It was performed for 24 sessions with Lee Hyeon-Jin's(2006) and Shin Ji-Hye and Kim Gui-Bok's(2009) group art therapy program. The evaluation was performed with Park Mi-Ran's self-esteem questionnaire(2007) and Kim Taehee's peer-relationship questionnaire(2005). The subjects are 26 elementary students in low-income and single parent family who are in the 2, 3, and 4 grade and use A-regional children center and B-regional children center which are located in Gyeongbuk province. Means, standard deviations, Independent t-test and Paired t-test were conducted. Firstly, the change in self-esteem of both experiment group and control group is investigated before and after their taking group art therapy program. There are statistically meaningful enhancements in self-esteem of experimental group. But there are no statistically meaningful enhancements in self-esteem of control group. Secondly, peer-relationships in both experimental group and control group do not change between before and after taking group art therapy program. Thus, the program of group art therapy is thought to be effective therapy improving the self-esteem of child in low-income single-parent family.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.7
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• pp.2328-2344
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• 2022

2D human pose estimation still faces difficulty in low-resolution images. Most existing top-down approaches scale up the target human bonding box images to the large size and insert the scaled image into the network. Due to up-sampling, artifacts occur in the low-resolution target images, and the degraded images adversely affect the accurate estimation of the joint positions. To address this issue, we propose a multi-resolution input feature fusion network for human pose estimation. Specifically, the bounding box image of the target human is rescaled to multiple input images of various sizes, and the features extracted from the multiple images are fused in the network. Moreover, we introduce a guiding channel which induces the multi-resolution input features to alternatively affect the network according to the resolution of the target image. We conduct experiments on MS COCO dataset which is a representative dataset for 2D human pose estimation, where our method achieves superior performance compared to the strong baseline HRNet and the previous state-of-the-art methods.

• Clinical and Experimental Reproductive Medicine
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• v.23 no.1
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• pp.95-102
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• 1996

This study was performed to investigate the effect of human follicular fluid (HFF) on development of mouse embryos, for evaluating the suitability of HFF as a substitutive material of human fetal cord serum in ART program. The various concentrations of HFF were added into the culture medium and the effects of HFF concentrations were examined to identify the optimal concentration of HFF for embryo development. The potency of HFF in improving embryo development was compared to that of other protein supplement. Collected HFFs were classified with the maturity of the containing oocytes; mature, immature, atretic, and then the effects of the classified HFFs on embryo development were examined. Also, HFF was separated into the low (<30,000 Da) and high (>30,000 Da) molecular weight fractions and the effects of the fractions on embryo development were investigated. The highest development rate was found in culture medium supplemented with 20% HFF, bnt this rate was reversely reduced at the concentrations of HFF higher than 20%. The development rates to the blastocyst, hatching blastocyst, attachment and outgrowth cultured in mature HFF was significantly higher than those in immature and atretic HFF, and mean cell number in blastocyst was higher in mature HFF than in immature and atretic HFF. The development rates of mouse embryos according to protein sources were significantly higher in HFF than in fetal cord serum (FCS), maternal serum (MS) and bovine serum albumin (BSA), and mean cell number in blastocyst cultured in HFF was higher than that in FCS, MS and BSA. The development rates of embryo and mean cell number in blastocyst cultured in high molecular weight fraction of HFF were higher than those in low molecular weight fraction, but the results of high molecular weight fraction were lower than those of whole HFF. Therefore, these results indicated that human mature follicular fluid was useful for improving the development of mouse embryos, which suggests a possibility that HFF also may be used efficiently for improving the culture condition in human ART program as a protein supplement.

• Korean Journal of Human Ecology
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• v.16 no.6
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• pp.1069-1082
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• 2007

The purpose of this study is to examine how integrative art therapy affected the interaction of children with developmental disorder with their mothers from the viewpoint of object-relation theory that accentuated mother role for the promotion of mother-child interaction, and based on earlier studies on mother-child interaction and the interaction of children with developmental disorder with their mothers. The subjects in this study are five selected children and their mothers who used B and G social welfare agencies in Gyeonggi province. They are at the age of five and six in Western age, and have difficulties interacting with their parents. When a social maturity test is conducted, their social age ranged from 2.1 to 3.9, and as Portage Test is implemented, their developmental levels of sociability, cognition and language were identical to those of younger children who were at the age of one to 3.5. The major findings of the study are as follows. First, the children who suffered from developmental disorder and participated in this study showed a positive change in their interaction with their mothers. Second, as for connections between each session and mother-child interaction, most of them came to interact with their mothers better as the program came to an end.

• Journal of Ginseng Research
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• v.41 no.2
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• pp.144-150
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• 2017

Background: The presence of gross deletions in the human immunodeficiency virus nef gene ($g{\Delta}nef$) is associated with long-term nonprogression of infected patients. Here, we investigated how quickly genetic defects in the nef gene are associated with Korean Red Ginseng (KRG) intakein 10 long-term slow progressors. Methods: This study was divided into three phases over a 20-yr period; baseline, KRG intake alone, and KRG plus highly active antiretroviral therapy (ART). nef gene amplicons were obtained using reverse transcription polymerase chain reaction (PCR) and nested PCR from 10 long-term slow progressors (n = 1,396), and nested PCR from 36 control patients (n = 198), and 28 ART patients (n = 157), and these were then sequenced. The proportion of $g{\Delta}nef$, premature stop codons, and not in-frame insertion or deletion of a nucleotide was compared between three phases, control, and ART patients. Results: The proportion of defective nef genes was significantly higher in on-KRG patients (15.6%) than in baseline (5.7%), control (5.6%), on-KRG plus ART phase (7.8%), and on-ART patients (6.6%; p < 0.01). Small in-frame deletions or insertions were significantly more frequent among patients treated with KRG alone compared with controls (p < 0.01). Significantly fewer instances of genetic defects were detected in samples taken during the KRG plus ART phase (7.8%; p < 0.01). The earliest defects detected were $g{\Delta}nef$ and small in-frame deletions after 7 mo and 67 mo of KRG intake, respectively. Conclusion: KRG treatment might induce genetic defects in the nef gene. This report provides new insight into the importance of genetic defects in the pathogenesis of AIDS.

• Journal of the Korean Society of Costume
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• v.58 no.1
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• pp.17-32
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• 2008

This study focuses on the analysis of Baudelaire's aesthetic perspective which has established a theoretical basis on research of the critical reviews' salon exhibitions as written by Baudelaire. Charles Pierre Baudelaire(1821-1867) having lived during the latter part of Neo-classicism and the era of Romanticism and Impressionism, Baudelaire displayed opposition to customary realities such as social ideology or religious authority that suppressed human nature. Also he pioneered a new genre known as art criticism and wrote much that provided important insights on the essential elements of artistic work, modernity and trend, as well as art definition and art categories. The aesthetic perspective and creative spirit were formed by Baudelaire, during his age were also reconfirmed in the successive ages of modernism and postmodernism. As such, this study sheds light on how Baudelaire's aesthetic perspective was not only temporarily assertion but it is consistently applied to modern art and fashion area. What is more important that, Baudelaire admired new artificial beauty that is created by the human soul liberated from natural instincts or desires. Especially, informed by strangeness and distinctiveness, Baudelaire's view of fashion ran along the same vein as his view of art, and these views form the basis of that creative spirit which situated western fashion on a center of the world. In conclusion, the research on Baudelaire's aesthetic perspective will reaffirm a firm awareness of the creative spirit essential to globally-oriented creative artists and designers who work within the circumstance of the 21st century, a time when the paving of new aesthetic paths is necessary. The research also offers a clear understanding of the aesthetic values demanded by this age.