• Transactions of the Korean hydrogen and new energy society
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• v.16 no.2
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• pp.103-110
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• 2005

Proton conducting solid polymer electrolyte (SPE) membranes have been used in many energy technological applications such as water electolysis, fuel cells, redox-flow battery, and other electrochemical devices. The availability of stable membranes with good electrochemical characteristics as proton conductivity at high temperatures above 80 $^{\circ}C$ and low cost are very important for its applications. However, the presently available perfluorinated ionomers are not applicable because of high manufacturing cost and high temperature use to the decrease in the proton conductivity and mechanical strength. In order to make up for the weak points, the block copolymer (BPSf) of polysulfone and poly (phenylene sulfide sulfone) were synthesized and sulfonated. The electrolyte membranes were prepared with phosphotungstic acid (HPA)/sulfonated BPSf via solution blending. This study would be desirable to investigate the interaction between the HPA and sulfonated polysulfone. The results showed that the characteristics of SPSf/HPA blend membrane was a better than Nafion at high temperature, 100 $^{\circ}C$. These membranes proved to have a high proton conductivity, $6.29{\times}10-2$ S/cm, a water content, 23.9%, and a ion exchange capacity, 1.97 meq./g dry membrane. Moreover, some of the membranes kept their high thermal and mechanical stability.

• Journal of Environmental Health Sciences
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• v.41 no.3
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• pp.147-162
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• 2015

Objectives: The objective of this review was to summarize the primary role of three representative endocrine axes in aquatic vertebrates and discuss the effects on endocrine systems and their interactions in teleost fish after exposure to environmental contaminants. Methods: We summarized individual traits and mechanisms for hormonal and transcriptional interactions between the hypothalamic-pituitary-gonad (HPG), hypothalamic-pituitary-thyroid (HPT), and hypothalamic-pituitary-adrenal (HPA) axes in fish. We also provided a brief discussion on the effects of nonylphenol-induced toxicity on endocrine systems and their interactions in fish as a demonstration of holistic explanation. Results: Currently-available data showed that thyroid dysfunction is associated with reproductive toxicity due to changes in steroidogenic gene expressions and sex hormone levels as well as gonad glands in fish. As an example, we demonstrated that exposure to nonylphenol could induce estrogenicity in male fish by decreasing thyroid hormones, which contributes to increased aromatase expression. Although the mechanisms are complicated and involved in multiple ways, a number of studies have shown that sex steroids influence the HPT axis or the HPA axis in fish, indicating bi-directional crosstalk. Critically missing is information on the primary target or toxicity mechanisms of environmental contaminants among the three endocrine axes, so further studies are needed to explore those possibilities. Conclusions: This review highlights the interactions between the HPG, HPT, and HPA axes in fish in order to better understand how these endocrine systems could interact with each other in situations of exposure to endocrine disrupting chemicals.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.17 no.1
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• pp.11-17
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• 2017

Purpose: Phenylketonuria (PKU) results from a deficiency of phenylalanine hydroxylase (PAH). The mutation of the PAH gene results in decreased phenylalanine hydroxylase enzyme activity in hyperphenylalaninemia (HPA) patients. This study reports ten cases of patients with the benign HPA genotype c.158G>A (p.Arg53His, R53H) variant in the PAH gene and aims to evaluate the clinical significance of the R53H variant. Methods: Ten Korean patients with the HPA genotype the R53H variant were included in this study. A retrospective medical record review was conducted. We characterized the phenotypes of the patients with HPA with the R53H variant using the following system: classic PKU, moderate PKU, mild PKU, Mild HPA, and benign HPA. Results: Five patients had the R53H variant with the "Pathogenic" variants (R413P, R241C, $Y356^*$, c.442-1G>A, $Y325^*$), Two patients had the "Likely pathogenic" variants ($W187^*$, A259T), Two patients had the "Uncertain significance" variants (R53H, G344D), and One patient had the "Not provided" variant (c.1066-14C>G). Nine patients genotyped with the R53H variant were the patient with benign HPA and One patient genotyped with the R53H homozygote was within normal range of plasma phenylalanine. None of the ten patients required dietary restriction of phenylalanine or pharmacotherapy to maintain their plasma phenylalanine levels and showed no clinical symptoms of HPA. Conclusion: Ten patients with HPA genotype the R53H variant were the patient with benign HPA and showed no clinical symptoms of HPA. Thus, the R53H variant, which was previously classified as an "Uncertain significance" mutation in HPA patients, should be re-classified as "Benign."

• Journal of Institute of Convergence Technology
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• v.4 no.2
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• pp.35-40
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• 2014

Human powered aircraft (HPA) is an airplane that uses only human power for its propulsion. It's development is completely different from conventional aircraft that use fuels as a power source. In the present study, special features for the development of HPA are discussed by studying the design requirements, weight estimation, aerodynamics and propulsion studies, power analysis, and mossion profile design. It is found that the development of the HPA is completely different from conventional aircraft. Mission profile is crucial to the successful flight of the sport HPA when the pilots are changed.

• Proceedings of the IEEK Conference
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• 2001.06a
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• pp.189-192
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• 2001

In this paper, We designed and implemented 20 watt high power amplifier which can be used for the commercial services in band of 1.86 ~ 1.870Hz at PCS. In order to satisfy ACPR, We designed by using the ADS(Advanced Design System)ver1.3. The HPA is fabricated on tepron substrate($\varepsilon_{{\gamma}}$ =3.15, H=0.78mm, T=0.02mm). The implemented HPA measured The ACPR characteristics at $\pm$ 885kHz, $\pm$ 1.25MHz, $\pm$2.25MHz. The HPA meets specification with good ACPR. The HPA is expected to use as a commercial product of PCS base station.roduct of PCS base station.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.11C
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• pp.1079-1086
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• 2007

In this paper, we propose a CCP (Companding Combined with Predistorter) scheme that maintains BER (Bit Error Rate) performance of systems, while effectively reducing PAPR (Peak-to-Average Power Ratio) of OFDM (Orthogonal Frequency Division Multiplexing) signals, independent of nonlinear property of HPAs (High Power Amplifiers). The proposed CCP scheme combines the conventional companding scheme proposed by the authors with the predistorter, in order to prevent degradation of BER performance caused by signal distortion from nonlinear property of the HPA and the compression property of the companding scheme. Hence, the proposed scheme effectively reduces the PAPR and simultaneously maintains the BER performance, independent of nonlinear property of the HPA. Simulation results showed that the proposed CCP scheme provides the lowest total degradation for all the modulations, when comparing with the companding scheme proposed by Wang and the clipping scheme.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.27 no.8
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• pp.725-734
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• 2016

Recently, novel candidate waveform techniques for spectral efficiency improvement was proposed in order to satisfy key performance indicators(KPIs) of 5th generation(5G) mobile communication. Multi-carrier based universal filtered multi-carrier(UFMC) and filter bank multi-carrier(FBMC) are very famous as 5G candidate waveform techniques. Also, weighted orthogonal frequency division multiplexing (W-OFDM) that has low-complexity is receiving the spotlight slowly. In this paper, firstly, we describe a basic OFDM system. And then, we also describe UFMC, FBMC, and W-OFDM system. Next, we evaluate and analyze spectrum and BER performance of these systems under the nonlinear high power amplifier(HPA) environment. As simulation results, spectrum characteristic and BER performance of UFMC, FBMC, and W-OFDM are similar to each other. Therefore, under the nonlinear HPA environment, W-OFDM system is more advantageous because W-OFDM system uses a simple time-domain windowing technique and has similar characteristics to the others.

• The korean journal of orthodontics
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• v.35 no.5 s.112
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• pp.341-350
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• 2005

The Purpose of this study was to compare the degree of vortical head rotation and to evaluate the reproducibility of natural Head posture (NHP) according to two guiding methods, the head posture aligner (HPA) method and the solf balance posture (SBP) method. The subjects consisted of 30 adults. On the first day. lateral and frontal cephalometric radiographs were obtained through the two guiding methods. One mouth later. lateral and frontal cephalometric radiographs were obtained again through both guiding methods. The degrees of vertical head rotation of both guiding methods were compared and the reproducibility was evaluated for each guiding method. A comparison of the degrees of vortical head rotation for the two methods revealed that the vertical head posture was lower in the SBP method than in the HPA method by an average of $2.79^{\circ}$. All measurements obtained using the HPA and SBP methods with a time interval of one north did not show any significant difierence in lateral and frortal cephalometric radiographs. The results of the present study suggest that the SBP method may be used as an alternative to the HPA method in case the HPA method can not be applied.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.6A
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• pp.488-498
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• 2005

The DAB(Digital Audio Broadcasting) service which is based on the Eureka-147 of Europe is developed to DMB(Digital Multimedia Broadcasting) service that is divided into Terrestrial DMB and Satellite DMB. The Satellite DMB is a new broadcasting service, which will service multi-channel multimedia broadcasting by the portable receiver or the vehicle receiver. In this paper, we consider that link level performance of satellite DMB system A which is based on the COFDM(Coded Orthogonal Division Multiplexing). It uses the OFDM method which is sensitive to nonlinearity, so we analyze the effect of the HPA(High Power Amplifier) nonlinearity. And then we define the appropriate back-off value by performing the link level simulation considering back-off effect. Also we consider the effect of frequency and time offset, and then confirm the overall link level performance by analyzing and verifying a suitable synchronization method for satellite DMB system A.

• Microbiology and Biotechnology Letters
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• v.32 no.3
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• pp.256-264
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• 2004

A new primer set was developed for the detection and identification of Xanthomonas oryzae pv. oryzae, the bacterial leaf blight (BLB) pathogen in rice plant. The nucleotide sequence of hpaA gene was determined from X. o. pv. oryzae str. KACC10331, and the sequence information was used to design primers for the application of the polymerase chain reaction (PCR). The nucleotide sequence of hpaA from X. o. pv. oryzae str. KACC 10331 was aligned with those of X. campestris pv. vesicatoria, X. campestris pv. campestris, X. axonopodis pv. citri, and X. axonopodis pv. glycines. Based on these results, a primer set(XOF and XOR) was designed for the specific detection of hpaA in X. o. pv. oryzae. The length of PCR products amplified using the primer set was 534-bp. The PCR product was detected from only X. o. pv. oryzae among other Xanthomonas strains and reference bacteria. This product was used to confirm the conservation of hpaA among Xanthomonas strains by Southern-blotting. Furthermore, PCR amplification with XOF and XOR was used to detect the pathogen in an artificially infected leaf. The sensitivity of PCR detection in the pure culture suspension was also determined. This PCR-based detection methods will be a useful method for the detection and identification of X. o. pv. oryzae as well as disease forecasting.