• Title/Summary/Keyword: Hold time

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Ussing's flux ratio theorem for nonlinear diffusive transport with chemical interactions

  • Bracken, A.J.;McNabb, A.;Suzuki, M.
    • 제어로봇시스템학회:학술대회논문집
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    • 1994.10a
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    • pp.747-752
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    • 1994
  • Ussing's flux ratio theorem (1978) reflects a reciprocal relationship behavior between the unidirectional fluxes in asymmetric steady diffusion-convection in a membrane slab. This surprising result has led to many subsequent studies in a wide range of applications, in particular involving linear models of time dependent problems in biology and physiology. Ussing's theorem and its extensions are inherently linear in character. It is of considerable interest to ask to what extent these results apply, if at all, in situations involving, for example, nonlinear reaction. A physiologically interesting situation has been considered by Weisiger et at. (1989, 1991, 1992) and by McNabb et al. (1990, 1991) who studied the role of albumin in the transport of ligands across aqueous diffusion barriers in a liver membrane slab. The results are that there exist reciprocal relationships between unidirectional fluxes in the steady state, although albumin is chemically interacting in a nonlinear way of the diffusion processes. However, the results do not hold in general at early times. Since this type of study first started, it has been speculated about when and how the Ussing's flux ratio theorem fails in a general diffusion-convection-reaction system. In this paper we discuss the validity of Ussing-type theorems in time-dependent situations, and consider the limiting time behavior of a general nonlinear diffusion system with interaction.

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Quadratic inference functions in marginal models for longitudinal data with time-varying stochastic covariates

  • Cho, Gyo-Young;Dashnyam, Oyunchimeg
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.3
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    • pp.651-658
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    • 2013
  • For the marginal model and generalized estimating equations (GEE) method there is important full covariates conditional mean (FCCM) assumption which is pointed out by Pepe and Anderson (1994). With longitudinal data with time-varying stochastic covariates, this assumption may not necessarily hold. If this assumption is violated, the biased estimates of regression coefficients may result. But if a diagonal working correlation matrix is used, irrespective of whether the assumption is violated, the resulting estimates are (nearly) unbiased (Pan et al., 2000).The quadratic inference functions (QIF) method proposed by Qu et al. (2000) is the method based on generalized method of moment (GMM) using GEE. The QIF yields a substantial improvement in efficiency for the estimator of ${\beta}$ when the working correlation is misspecified, and equal efficiency to the GEE when the working correlation is correct (Qu et al., 2000).In this paper, we interest in whether the QIF can improve the results of the GEE method in the case of FCCM is violated. We show that the QIF with exchangeable and AR(1) working correlation matrix cannot be consistent and asymptotically normal in this case. Also it may not be efficient than GEE with independence working correlation. Our simulation studies verify the result.

Residence Time Distributions of Liquid pbase Flow and Mass Transfers in the Trickle Bed Reactor (점적상 반응기에서 액상흐름의 체류시간 분포 및 물질전달)

  • Kim, Ki-Chang
    • Journal of Industrial Technology
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    • v.6
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    • pp.19-31
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    • 1986
  • The residence time distribution of liquid flow in a 4.0cm diameter column packed with porous $Al_2O_3$ spheres of 0.37cm diameter were measured with pulse injections of a tracer under cocurrent trickling flow conditions. The mean residence time of liquid flow and liquid hold-up calculated by the transient curve of tracer were unaffected by gas flow rates under experimental ranges of liquid flow rates from 2.4 to $4.5(kg/m^2\;sec)$ and gas flow rates from 0 to $0.13(kg/m^2\;sec)$. The axial dispersion coefficient of liquid stream and apparent diffusivity of tracer in a micropore of solid particle were estimated from the response curve of tracer. The calculated Peclet No. were increased in ranges of 68-to 82 with a increasing of liquid mass velocity, and the external effective contacting efficiency between liquid and solid which can be expressed. by $(D_i)_{app}/D_i$ varied in ranges of 0.54 to 0.68 depending on the liquid flow rates. The gas to liquid(water) volumetric mass transfer coefficient were determined from desorption experiments with oxygen at $25^{\circ}C$ and 1 atm. The measured mass transfer coefficients were increased with liquid flow rates and the effect of gas flow rates on the mass transfer coefficient was insignificant.

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The Properties of Acoustic in Multi-purpose out-door Stadium II - a case study of seoul world cup stadium measurement - (다목적 야외경기장의 음향특성에 관한 연구 II -서울월드컵 경기장의 전기음향시스템고찰과 음향측정을 중심으로-)

  • 김정중;손장열
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2002.05a
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    • pp.731-739
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    • 2002
  • recently out door stadiums have been built as multi purpose stadium for athletic sports It hold but also various events and huge concerts. in the past, out-door stadium usually was built, but recently the out-door stadium which of the 50 % of roof covered by doom have been built increasingly. as the result, the sound obstacle is becoming very important. but a design of sound has become unplaned except some of the stadium, also rarely been built by sound-absorption material. as the result, the purpose of this study is investigating, analyzing the theory for plan of electric acoustic sound, a drawing of acoustic design and measurement a result value, comparison, evaluating a main sound factor with criteria of the Seoul City design. and reservation time, clearness, sound pressure level suitable for using purpose, so the necessary quantities will be added to financial budget of building acoustic design. and For verification, this contains acoustic analyser measurement and computer simulation and this study will find the solution of helping method.

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Reliability Analysis of MLCC Degradation Data based on Eyring Model (아이링 모델에 기초한 MLCC 열화데이터의 신뢰성 해석)

  • 김종철;김광섭;차종범
    • Proceedings of the Korean Reliability Society Conference
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    • 2004.07a
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    • pp.239-246
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    • 2004
  • Accelerated degradation test (ADT) can be a useful tool for assessing the reliability when few or even no failure are expected in an accelerated life test. In this paper, MLCC (Multilayer Ceramic Capacitors), a sort of passive components which have large capacitance(X7R -55$^{\circ}C$~1$25^{\circ}C$) have been tested, and least-square analyses are used to illustrate our approach in which amount of degradation of a DUT following log-normal distribution. We assumed a simple and useful linear model to describe the amount of degradation over time subjected to different voltage levels applied. Tests for linearity of the performance-time relationship, and provide tests for how well the assumptions hold. Also, by using Eyring Model, MLCC's mean life time is assessed.

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Elevated Temperature Design of KALIMER Reactor Internals Accounting for Creep and Stress-Rupture Effects

  • Koo, Gyeong-Hoi;Bong Yoo
    • Nuclear Engineering and Technology
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    • v.32 no.6
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    • pp.566-594
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    • 2000
  • In most LMFBR(Liquid Metal Fast Breed Reactor) design, the operating temperature is very high and the time-dependent creep and stress-rupture effects become so important in reactor structural design. Therefore, unlike with conventional PWR, the normal operating conditions can be basically dominant design loading because the hold time at elevated temperature condition is so long and enough to result in severe total creep ratcheting strains during total service lifetime. In this paper, elevated temperature design of the conceptually designed baffle annulus regions of KALIMER(Korea Advanced Liquid MEtal Reactor) reactor internal strictures is carried out for normal operating conditions which have the operating temperature 53$0^{\circ}C$ and the total service lifetime of 30 years. For the elevated temperature design of reactor internal structures, the ASME Code Case N-201-4 is used. Using this code, the time-dependent stress limits, the accumulated total inelastic strain during service lifetime, and the creep-fatigue damages are evaluated with the calculation results by the elastic analysis under conservative assumptions. The application procedures of elevated temperature design of the reactor internal structures using ASME Code Case N-201-4 with the elastic analysis method are described step by step in detail. This paper will be useful guide for actual application of elevated temperature design of various reactor types accounting for creep and stress-rupture effects.

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Enhanced Privacy Preservation of Cloud Data by using ElGamal Elliptic Curve (EGEC) Homomorphic Encryption Scheme

  • vedaraj, M.;Ezhumalai, P.
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.14 no.11
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    • pp.4522-4536
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    • 2020
  • Nowadays, cloud is the fastest emerging technology in the IT industry. We can store and retrieve data from the cloud. The most frequently occurring problems in the cloud are security and privacy preservation of data. For improving its security, secret information must be protected from various illegal accesses. Numerous traditional cryptography algorithms have been used to increase the privacy in preserving cloud data. Still, there are some problems in privacy protection because of its reduced security. Thus, this article proposes an ElGamal Elliptic Curve (EGEC) Homomorphic encryption scheme for safeguarding the confidentiality of data stored in a cloud. The Users who hold a data can encipher the input data using the proposed EGEC encryption scheme. The homomorphic operations are computed on encrypted data. Whenever user sends data access permission requests to the cloud data storage. The Cloud Service Provider (CSP) validates the user access policy and provides the encrypted data to the user. ElGamal Elliptic Curve (EGEC) decryption was used to generate an original input data. The proposed EGEC homomorphic encryption scheme can be tested using different performance metrics such as execution time, encryption time, decryption time, memory usage, encryption throughput, and decryption throughput. However, efficacy of the ElGamal Elliptic Curve (EGEC) Homomorphic Encryption approach is explained by the comparison study of conventional approaches.

Low-Power ECG Detector and ADC for Implantable Cardiac Pacemakers (이식형 심장 박동 조율기를 위한 저전력 심전도 검출기와 아날로그-디지털 변환기)

  • Min, Young-Jae;Kim, Tae-Geun;Kim, Soo-Won
    • Journal of IKEEE
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    • v.13 no.1
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    • pp.77-86
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    • 2009
  • A wavelet Electrocardiogram(ECG) detector and its analog-to-digital converter(ADC) for low-power implantable cardiac pacemakers are presented in this paper. The proposed wavelet-based ECG detector consists of a wavelet decomposer with wavelet filter banks, a QRS complex detector of hypothesis testing with wavelet-demodulated ECG signals, and a noise detector with zero-crossing points. To achieve high-detection performance with low-power consumption, the multi-scaled product algorithm and soft-threshold algorithm are efficiently exploited. To further reduce the power dissipation, a low-power ADC, which is based on a Successive Approximation Register(SAR) architecture with an on/off-time controlled comparator and passive sample and hold, is also presented. Our algorithmic and architectural level approaches are implemented and fabricated in standard $0.35{\mu}m$ CMOS technology. The testchip shows a good detection accuracy of 99.32% and very low-power consumption of $19.02{\mu}W$ with 3-V supply voltage.

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On-chip Power Supply Noise Measurement Circuit with 2.06mV/count Resolution (2.06mV/count의 해상도를 갖는 칩 내부 전원전압 잡음 측정회로)

  • Lee, Ho-Kyu;Jung, Sang-Don;Kim, Chul-Woo
    • Journal of IKEEE
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    • v.13 no.4
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    • pp.9-14
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    • 2009
  • This paper describes measurement of an on-ship power supply noise in mixed-signal integrated circuits. To measure the on-chip power supply noise, we can check the effects of analog circuits and compensate it. This circuit consists of two independent measurement channels, each consisting of a sample and hold circuit and a frequency to digital converter which has a buffer and voltage controlled oscillator(VCO). The time-based voltage information and frequency-based power spectrum density(PSD) can be achieved by a simple analog to digital conversion scheme. The buffer works like a unit-gain buffer with a wide bandwidth and VCO has a high gain to improve resolution. This circuit was fabricated in a 0.18um CMOS technology and has 2.06mV/count. The noise measurement circuit consumes 15mW and occupies $0.768mm^2$.

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A Study on the Environmental Design Principles and Cultural Landscape Pattern of the Hahoe. the Yangdong Traditional Village (하회.양동마을에 작용된 환경설계원칙과 문화경관상)

  • 신상섭
    • Journal of Environmental Science International
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    • v.12 no.4
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    • pp.383-391
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    • 2003
  • The purpose of this research explain the meaning of the environmental design principles and cultural landscape pattern(dualistic space organization) of the Hahoe(河回:winding river village) the Yangdong(良洞) traditional village. Village's space organizations based on Shamanism, fin-yang and Five elements principle, Feng-shui idea, social system and Confucian ideas. And it were accomplish curat landscape pattern(village:form+object=pattern) through the frame of settlement space. As a central persons of villages(the Hahoe $.$ the Yangdong) construction, Suhae(西厓) experienced tough Chunghyodang - Wonjichongsa - Ogyonchongsa - Pyongsansowon channel(忠孝堂 -遠志精舍 -玉端精含 -脣山書院) and Kyomam(謙 ) experienced tough Yangjindang - Binyeonchongsa - Kyomamchongsa - Hwachonsodang(養眞堂 - 賓淵精舍 - 謙庵f精舍 - 花川書堂) channel. Also Woojae(愚齋) experienced tough Suhbackdang - Khankachung - Dongkangsowon(書百堂 - 觀稼停 - 東江書院) and Hoejae(晦齋) experienced tough Moochumdang - Hyangdan - Oaksansowon(無添堂 - 香壇 - 玉山書院). It is space organization of themselves interact contrast and sequence principles with competition in good faith. And ecological art-space, that is, environmental spare organizations of traditional village has been reflected harmony between nature and artificiality, spatial rhythm and sequence, spatial hierarchy between upper classes and humble class, permeability space, asymmetrical balance, aesthetic space perception. The humble classes hold a ceremony Hahoe's Pyolsingut-Talnori(maskdance drama), Dangjae(堂祭:religious service) at the Dang(堂:shamanism spot) and Yangdong's Sohraesulnori, Hohminori. And the upper class hold a ceremony Hahoe's Julbulnori and Yangdong's Chungjanori connected with culture of confucianism. Specially, the cultural structure cf the village is evidence of a contrast between the upper class and the humble classes, time, method and location of ceremony(performance).