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Portable Low-Cost MRI System Based on Permanent Magnets/Magnet Arrays

  • Huang, Shaoying;Ren, Zhi Hua;Obruchkov, Sergei;Gong, JIa;Dykstra, Robin;Yu, Wenwei
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.3
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    • pp.179-201
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    • 2019
  • Portable low-cost magnetic resonance imaging (MRI) systems have the potential to enable "point-of-care" and timely MRI diagnosis, and to make this imaging modality available to routine scans and to people in underdeveloped countries and areas. With simplicity, no maintenance, no power consumption, and low cost, permanent magnets/magnet arrays/magnet assemblies are attractive to be used as a source of static magnetic field to realize the portability and to lower the cost for an MRI scanner. However, when taking the canonical Fourier imaging approach and using linear gradient fields, homogeneous fields are required in a scanner, resulting in the facts that either a bulky magnet/magnet array is needed, or the imaging volume is too small to image an organ if the magnet/magnet array is scaled down to a portable size. Recently, with the progress on image reconstruction based on non-linear gradient field, static field patterns without spatial linearity can be used as spatial encoding magnetic fields (SEMs) to encode MRI signals for imaging. As a result, the requirements for the homogeneity of the static field can be relaxed, which allows permanent magnets/magnet arrays with reduced sizes, reduced weight to image a bigger volume covering organs such as a head. It offers opportunities of constructing a truly portable low-cost MRI scanner. For this exciting potential application, permanent magnets/magnet arrays have attracted increased attention recently. A magnet/magnet array is strongly associated with the imaging volume of an MRI scanner, image reconstruction methods, and RF excitation and RF coils, etc. through field patterns and field homogeneity. This paper offers a review of permanent magnets and magnet arrays of different kinds, especially those that can be used for spatial encoding towards the development of a portable and low-cost MRI system. It is aimed to familiarize the readers with relevant knowledge, literature, and the latest updates of the development on permanent magnets and magnet arrays for MRI. Perspectives on and challenges of using a permanent magnet/magnet array to supply a patterned static magnetic field, which does not have spatial linearity nor high field homogeneity, for image reconstruction in a portable setup are discussed.

The Effects of STEAM Program on Preservice Science Teachers' Communication Competency: Their Experiences and Reflection on STEAM Education (STEAM 프로그램이 예비 과학교사의 의사소통역량에 미치는 영향: STEAM 교육에 대한 경험과 성찰)

  • Kim, Sun Young;Jeon, Jae Hyeong
    • Journal of Science Education
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    • v.43 no.1
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    • pp.136-156
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    • 2019
  • This study examined the effects of STEAM program on preservice science teachers' communication competency and further explored their experiences of and reflection on STEAM program. The study design is one group pretest-posttest with mixed methodology using both quantitative and qualitative data. The STEAM program consists of three stages: introduction of STEAM, participation in STEAM activities, and reflection on the STEAM program. The preservice science teachers improved their communication competency after the STEAM program (p < .01). The preservice science teachers represented statistically higher scores on the three subscales of communication competency: Interpretation ability, self-presenting ability, and understanding others' viewpoints. In addition, the preservice science teachers reflected on their STEAM experiences. During the first stage of 'Presentation of the Problem Situation,' the preservice science teachers mentioned that they roused their curiosity due to everyday experience-related, social issues or present issues. In the stage of 'Creative Design,' the preservice science teachers mentioned that they selected the final idea through mutual consent of the members, the practical possibility of everyday life, the previous experience-based decisions, or persuasive power. Further, about 87.5% of preservice science teachers mentioned that they were fully engaged in the 'Emotional Learning' stages due to the application of integrated thinking, everyday related issues, and communication among group members. About 85% of the preservice science teachers mentioned that they could challenge new problems in future situations.

A Study on Design of Wind Blade with Rated Capacity of 50kW (50kW 풍력블레이드 설계에 관한 연구)

  • Kim, Sang-Man;Moon, Chae-Joo;Jung, Gweon-Sung
    • The Journal of the Korea institute of electronic communication sciences
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    • v.16 no.3
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    • pp.485-492
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    • 2021
  • The wind turbines with a rated capacity of 50kW or less are generally considered as small class. Small wind turbines are an attractive alternative for off-grid power system and electric home appliances, both as stand-alone application and in combination with other energy technologies such as energy storage system, photovoltaic, small hydro or diesel engines. The research objective is to develop the 50kW scale wind turbine blades in ways that resemble as closely as possible with the construction and methods of utility scale turbine blade manufacturing. The mold process based on wooden form is employed to create a hollow, multi-piece, lightweight design using carbon fiber and fiberglass with an epoxy based resin. A hand layup prototyping method is developed using high density foam molds that allows short cycle time between design iterations of aerodynamic platforms. A production process of five blades is manufactured and key components of the blade are tested by IEC 61400-23 to verify the appropriateness of the design. Also, wind system with developed blades is tested by IEC 61400-12 to verify the performance characteristics. The results of blade and turbine system test showed the available design conditions for commercial operation.

Application of the Proper Air Supply Amount Based on the Influent Water Quality for the Development of Efficient Blower Control Logic in Sewage Treatment Plants (하수처리장의 효율적인 Blower Control Logic 개발을 위한 유입수질 기반 공기공급량 적용 연구)

  • Yeo, Wooseok;Kim, Jong Kyu
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.4
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    • pp.493-499
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    • 2022
  • The standards pertaining to the quality of discharged water in sewage treatment plants are strengthening, and accordingly, facilities in sewage treatment plants are being upgraded. In addition, the discharge water quality of sewage treatment plants must be maintained at a high level, and efficient sewage treatment plant operations have thus emerged as a very important issue. For the efficient operation of sewage treatment plants, this study applied a basic blowing amount calculation method based on sewage facilities to evaluate the required oxygen amount and blowing amount according to inflow water quality by logicizing various influencing factors. As a result of calculating the amount of air blown by applying actual April water quality data from sewage treatment plant A to the blower demand calculation developed through this study, it was found that the average amount of air blown was reduced by about 12%. When the blower demand calculation developed here is applied to an actual sewage treatment plant, the amount of air blown can be controlled based on the inflow water quality. This can facilitate the realization of an autonomous control of sewage treatment plants, in contrast to the existing sewage treatment operation method that relies on operational experience of operator. In addition, it is expected that efficient sewage treatment plants can be operated by reducing blowing amounts and power costs, which will contribute to both energy and carbon savings.

The Korea Cohort Consortium: The Future of Pooling Cohort Studies

  • Lee, Sangjun;Ko, Kwang-Pil;Lee, Jung Eun;Kim, Inah;Jee, Sun Ha;Shin, Aesun;Kweon, Sun-Seog;Shin, Min-Ho;Park, Sangmin;Ryu, Seungho;Yang, Sun Young;Choi, Seung Ho;Kim, Jeongseon;Yi, Sang-Wook;Kang, Daehee;Yoo, Keun-Young;Park, Sue K.
    • Journal of Preventive Medicine and Public Health
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    • v.55 no.5
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    • pp.464-474
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    • 2022
  • Objectives: We introduced the cohort studies included in the Korean Cohort Consortium (KCC), focusing on large-scale cohort studies established in Korea with a prolonged follow-up period. Moreover, we also provided projections of the follow-up and estimates of the sample size that would be necessary for big-data analyses based on pooling established cohort studies, including population-based genomic studies. Methods: We mainly focused on the characteristics of individual cohort studies from the KCC. We developed "PROFAN", a Shiny application for projecting the follow-up period to achieve a certain number of cases when pooling established cohort studies. As examples, we projected the follow-up periods for 5000 cases of gastric cancer, 2500 cases of prostate and breast cancer, and 500 cases of non-Hodgkin lymphoma. The sample sizes for sequencing-based analyses based on a 1:1 case-control study were also calculated. Results: The KCC consisted of 8 individual cohort studies, of which 3 were community-based and 5 were health screening-based cohorts. The population-based cohort studies were mainly organized by Korean government agencies and research institutes. The projected follow-up period was at least 10 years to achieve 5000 cases based on a cohort of 0.5 million participants. The mean of the minimum to maximum sample sizes for performing sequencing analyses was 5917-72 102. Conclusions: We propose an approach to establish a large-scale consortium based on the standardization and harmonization of existing cohort studies to obtain adequate statistical power with a sufficient sample size to analyze high-risk groups or rare cancer subtypes.

An Experimental Study on Electrical Energy Generation Based on Phase Change Materials for Application of Underwater Unmanned Vehicles (수중 무인 이동체 적용을 위한 상변화물질 기반의 전기 에너지 생성에 대한 실험적 연구)

  • Yeon-Chul Ha
    • Journal of the Institute of Convergence Signal Processing
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    • v.23 no.4
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    • pp.228-233
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    • 2022
  • This study is an experimental study on how to use phase change materials(PCM) to generate electrical energy for long-term operation of underwater unmanned vehicles. The electrical energy generation method is a volume change and a pressure change that occur as a phase change material changes to a solid or liquid state according to temperature, and the change in pressure creates a flow of fluid to create electrical energy. Polyethylene glycol was used as a phase change material considering the temperature of the ocean. In addition, an electrical energy generating device that converts volume change into pressure at low temperature (1℃~2℃) in solid state and high temperature (21℃~25℃) in liquid state was fabricated. As a result of the experiment, the pressure change according to the phase change rapidly changed between 1 hour and 2 hours, and maintained a pressure of about 24MPa after 4 hours. Through this, it was confirmed that it can be used as a power source for underwater unmanned vehicles using phase change materials and temperature differences. In addition, it was found that a more improved design should be made in order to apply the phase change material to an underwater unmanned vehicle.

Changes of Soil Temperature and Moisture under the Agrivoltaic Systems in Fallow Paddy Field during Spring Season (봄철 영농형 태양광 시설 하부 휴경논 토양의 온도와 수분 변화)

  • Yuna Cho;Euni Cho;Jae-Hyeok Jeong;Hoejeong Jeong;Woon-Ha Hwang;Jaeil Cho
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.25 no.3
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    • pp.218-225
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    • 2023
  • An agrivoltaic system (AVS) is a combined system that generates power through photovoltaic panels (PVPs) installed above a field where a crop is cultivated. Although soil moisture is an important limiting factor for open-field crop production, particularly during spring season in Korea, it is not well considered in the utilization of AVS. Indeed, the application of water-energy-food nexus on the AVS should be necessary. In this study, the changes of soil moisture and temperature under the AVS was investigated in fallow paddy field during spring season. The AVS that has partial shading condition by PV panels was decreased soil temperature and increased soil moisture compared to open-field. Furthermore, the maximum of the change in soil moisture to the change in soil temperature had a negative correlation both on open-field and AVS under wet condition. It represents that the micro-climate under the AVS is in energy-limited condition. The open-field of relatively high soil temperature was in water-limited condition. The different behavior of soil moisture on the AVS should be considered for the sustainable agricultural system as related to water-energy-food nexus.

A Study on Antioxidant and Antibacterial Efficacy Evaluation and Cosmetic Application of Rumex crispus L. Root Extract (소루쟁이 뿌리 추출물(Rumex crispus L.)의 라디칼 소거능과 항균력 평가 및 화장품 적용 가능성에 관한 연구)

  • Yu-Jin Park;Jae-Chan Yang
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.2
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    • pp.159-171
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    • 2024
  • This study confirmed the antioxidant activity and antimicrobial efficacy and formulation stability for the effectiveness experiment of Rumex crispus. L root extract. For antioxidant activity, DPPH radical scavenging, FRAP activity, ABTS+ radical scavenging, and SOD-like activity were performed. Antimicrobial activity was evaluated for Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans strains. In addition, skin containing Rumex crispus. L root extract is checked over time for pH, temperature, and daylight for 21 days. As a result of antioxidant evaluation, it was confirmed that the activity increased in a concentration-dependent manner at a concentration of 0.0625-1 mg/mL. The clear zones of each bacterium at 100mg/mL concentrations were 10.45±0.34, 9.77±0.59, 9.92±0.22, and 10.08±0.12, which were superior to the control group Methyl paraben, and the antibacterial power of S. aureus and E. coli was confirmed at 100mg/mL concentration for MIC. There was little change in absorbance when the pH of the skin was 4.0, 6.0, and 7.0 and At 4℃, 25℃, and 40℃, it was discolored as the temperature increased. It was also observed that discoloration occurred when exposed to daylight. This is presumed to be able to prevent discoloration when it is shielded and stored at low temperatures. When the results of this study are summarized, Rumex crispus. L root extract is considered to have high value in use as a cosmetic raw material that can expect antioxidant and antibacterial activities.

End to End Model and Delay Performance for V2X in 5G (5G에서 V2X를 위한 End to End 모델 및 지연 성능 평가)

  • Bae, Kyoung Yul;Lee, Hong Woo
    • Journal of Intelligence and Information Systems
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    • v.22 no.1
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    • pp.107-118
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    • 2016
  • The advent of 5G mobile communications, which is expected in 2020, will provide many services such as Internet of Things (IoT) and vehicle-to-infra/vehicle/nomadic (V2X) communication. There are many requirements to realizing these services: reduced latency, high data rate and reliability, and real-time service. In particular, a high level of reliability and delay sensitivity with an increased data rate are very important for M2M, IoT, and Factory 4.0. Around the world, 5G standardization organizations have considered these services and grouped them to finally derive the technical requirements and service scenarios. The first scenario is broadcast services that use a high data rate for multiple cases of sporting events or emergencies. The second scenario is as support for e-Health, car reliability, etc.; the third scenario is related to VR games with delay sensitivity and real-time techniques. Recently, these groups have been forming agreements on the requirements for such scenarios and the target level. Various techniques are being studied to satisfy such requirements and are being discussed in the context of software-defined networking (SDN) as the next-generation network architecture. SDN is being used to standardize ONF and basically refers to a structure that separates signals for the control plane from the packets for the data plane. One of the best examples for low latency and high reliability is an intelligent traffic system (ITS) using V2X. Because a car passes a small cell of the 5G network very rapidly, the messages to be delivered in the event of an emergency have to be transported in a very short time. This is a typical example requiring high delay sensitivity. 5G has to support a high reliability and delay sensitivity requirements for V2X in the field of traffic control. For these reasons, V2X is a major application of critical delay. V2X (vehicle-to-infra/vehicle/nomadic) represents all types of communication methods applicable to road and vehicles. It refers to a connected or networked vehicle. V2X can be divided into three kinds of communications. First is the communication between a vehicle and infrastructure (vehicle-to-infrastructure; V2I). Second is the communication between a vehicle and another vehicle (vehicle-to-vehicle; V2V). Third is the communication between a vehicle and mobile equipment (vehicle-to-nomadic devices; V2N). This will be added in the future in various fields. Because the SDN structure is under consideration as the next-generation network architecture, the SDN architecture is significant. However, the centralized architecture of SDN can be considered as an unfavorable structure for delay-sensitive services because a centralized architecture is needed to communicate with many nodes and provide processing power. Therefore, in the case of emergency V2X communications, delay-related control functions require a tree supporting structure. For such a scenario, the architecture of the network processing the vehicle information is a major variable affecting delay. Because it is difficult to meet the desired level of delay sensitivity with a typical fully centralized SDN structure, research on the optimal size of an SDN for processing information is needed. This study examined the SDN architecture considering the V2X emergency delay requirements of a 5G network in the worst-case scenario and performed a system-level simulation on the speed of the car, radius, and cell tier to derive a range of cells for information transfer in SDN network. In the simulation, because 5G provides a sufficiently high data rate, the information for neighboring vehicle support to the car was assumed to be without errors. Furthermore, the 5G small cell was assumed to have a cell radius of 50-100 m, and the maximum speed of the vehicle was considered to be 30-200 km/h in order to examine the network architecture to minimize the delay.

Skin Improvement Effects and Development of Liposome Capsule Technology Using Centella Asiatica Extract Powder (센텔라아시아티카정량추출물의 리포좀 캡슐기술 개발과 피부개선효과)

  • Kim, Seong Jang;Ju, Yeon Jeong;Kim, In-Young
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.5
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    • pp.1285-1297
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    • 2020
  • In this study, we report the results of a study on the clinical evaluation of wrinkle improvement by developing a method for liposome of high-purity Centella asiatica extract used in pharmaceuticals and cosmetics, and a cream using the same. In order to make Centellasome-10EX stabilizing centella asiatica extract in liposome lamella vesicle, it could be completed using 5% hydrogenated lecithin and 2% sucrose distearate. The appearance of Centellasome-10EX was a creamy form of low viscosity, the color was pale yellow, and the odor had the inherent odor of the raw material. The pH was about 6.12, the specific gravity was 1.09, and the acid value was about 0.35. The content of the main constituents of centella asiatica extract contained in the liposome vesicle contains 10,800 ppm of asiatic acid, 10,900 ppm of asiaticoside, 6,000 ppm of madecasic acid, and 1,600 ppm of madecassoside, and long-term storage. There was no discoloration even at the time, and it was found that the main component remained stable thermodynamically. To mechanistically analyze the structure of the liposome vesicle of Centellasome-10EX, as a result of observation with a transmission electron microscope (Cryo-TEM), the multilayer vesicles are formed and filled with moisture, and there are 10 to 60 multilayers around it. It was confirmed that the liposome lamella vesicle was formed. As a clinical trial (in-vivo) test, the moisturizing effect of centellasome cream after application for 5 weeks was 28.3%, which was significantly increased compared to placebo. The skin elasticity effect was 13.6%, which significantly increased the moisturizing power than the placebo. The effect of improving fine wrinkles around the eyes was improved by 23.52% compared to placebo cream. Through the results of this study, it was possible to study the formulation and manufacturing method for encapsulation and stabilization of the developed Centellasome-10EX in the liposome vesicle. It is expected that the results obtained through clinical research on the wrinkle improvement effect of the cream using this can be widely used to study skin science in the cosmetic industry and to develop high-quality cosmetics with high efficacy.