• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2000년도 추계학술발표대회 및 bio-venture fair
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• pp.73-76
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• 2000

A novel, continuous bioreactor system combining a bubble column (absorption section) and a two-phase bioreactor (degradation section) has been designed to treat a gas stream containing benzene. The bubble column contained hexadecane as an absorbent for benzene, and was systemically chosen considering physical, biological, environmental, operational and economic factors. This solvent has infinite solubility for benzene and very low volatility. After absorbing benzene in the bubble column, the hexadecane served as the organic phase of the two-phase partitioning bioreactor, transferring benzene into the aqueous phase where it was degraded by Alcaligenes xylosoxidans Y234. The hexadecane was then continuously recirculated back to the absorber section for the removal of additional benzene. All mass transfer and biodegradation characteristics in this system were investigated prior to operation of the integrated unit, and these included: the mass transfer rate of benzene in the absorption column, the mass transfer rate of benzene from the organic phase into the aqueous phase in the two-phase bioreactor, the stripping rate of benzene out of the two-phase bioreactor, etc. All of these parameters were incorporated into model equations, which were used to investigate the effects of operating conditions on the performance of the system. Several experiments were conducted to show the feasibility of this system. This process is believed to be very practical for the treatment of high concentrations of gaseous pollutants.

• Applied Biological Chemistry
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• 제48권2호
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• pp.109-114
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• 2005

토양 시료로부터 n-hexadecane 대사능을 가지며 배양액의 표면장력을 감소시키고, 탄화수소를 가장 잘 유화시키는 세균을 oil-film collapsing 방법을 통해 선별하였다. 세균은 Bacillus sp.로 부분동정되었으며, BJS-51로 명명하였다. 생물계면활성제의 최적 생산에는 n-hexadecane이 가장 효과적인 탄소원이었으며, 3%의 농도일 때 표면장력이 76 dyne/cm에서 31 dyne/cm로 감소하였다. 이 때, CMD(critical micelle dilution)가 5.7로 가장 높았다. 질소원으로는 $(NH_4)_2HPO_4$가 가장 효과적이었으며, C/N ratio가 60인 경우 표면장력이 29 dyne/cm, CMD가 9.2로 가장 활성이 좋았다. 생산 최적 pH는 7.2였으며, 최적 온도는 $30^{\circ}C$였다. Bacillus sp. BJS-51에 의해 생산된 생물계면활성제를 유기용매추출법과 preparative HPLC systems을 통해 추출, 정제하였다. 각종 발색 시약으로 정제된 생물계면활성제의 생화학적 성질을 조사한 결과, 지질다당임을 확인 할 수 있었다. 생산된 생물계면활성제의 표면장력은 27 dyne/cm까지 감소하였으며, CMC(critical micelle concentration)는 0.08 g/l였다. 상기의 최적조건에서 생물계면활성제의 생산량은 CMD값이 9.2이었으므로 약 0.74 g/l이었다. 생산된 생물계면활성제는 $pH\;2{\sim}12$ 사이에서 표면장력 $29{\sim}31\;dyne/cm$로 안정하였으며, $100^{\circ}C$에서 60분간 열을 가한 후에도 표면장력 $29{\sim}30\;dyne/cm$로 안정하였다.

• Toxicological Research
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• 제6권1호
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• pp.1-12
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• 1990

Effect of red ginseng treatment on experimentally induced hyperkeratosis was investigated by light microscopic observation scanning electron microxcope (SEM) examination, epidermal enzyme activities nd lipid contents. Both light microscopic observation and SEM examination showed that hexadecane induced epidermal hyperplasia, hypertrophy and hyperkeratosis by increasing the numbers as well as the sizes of epidermal cells including desquamating horny cells. The superficial horny cells were protruded around the base of hair shaft. Among red ginseng components, only saponin treatment inhibited epidermal hyperplasia and hyperkeratosis by reducing the thickness of epidermis and arranging the cornified cells. Saponin from korean red ginseng inhibited abnormally increased epidermal LDH, ICD and G6PDH activities and reduced the contents of epidermal lipids induced by hexadecane. It seems that red ginseng saponin has preventive effect on experimental hyperkeratosis possibly by controlling the enzyme activities involved in epidermal cellular metabolism, resulting in reduced amounts of abnormal epidermal lipids.

• 한국분무공학회지
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• 제4권1호
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• pp.27-33
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• 1999

An experimental study has been conducted to clarify the effect of vapor on droplet evaporation. Droplets of water, ethanol, n-hexadecane and n-heptane were exposed in air stream. Temperature, pressure, and flow velocity in the ambient air are 470K, 1 atm, and 2m/s, respectively. Measurements are carried out for the wide range of water vapor concentration$(0%\sim40%)$. To obtain the time histories of droplet diameter, suspended droplet in hot and humid air stream was synchronized with a back flash light, and enlarged droplet images were taken on a CCD camera. With the vapor concentration increasing, the evaporation rate constant of water droplet decrease slightly and the droplet of ethanol and n-heptane increase actively. The evaporation rate constant of n-hexadecane which has higher boiling point than water increases within around 30% of the concentration.

• 한국응용과학기술학회지
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• 제29권1호
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• pp.116-121
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• 2012

본 연구에서 황색 발색제는 피리딘 존재 하에 ${\alpha}$-pivaloyl-2-chloro-5-amino- acetaniline hydrogen chloride와 1-hexadecane sulfonyl chloride를 반응시켜 얻었다. 이 물질은 다양한 분석장비를 이용하여 녹는점, 원소분석기, 적외선분석기, 자외선분석기, 질량분석기로 확인하였다. 황색 발색제를 CD-3(발색현상주약)와 반응시키면 황색이 나타났다.

• 한국미생물·생명공학회지
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• 제17권3호
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• pp.252-256
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• 1989

해수환경에서 Bunker-C유를 가장 강력히 유화분산시키는 Acilromobacter sp. M-1220 균주를 대상으로 하여 생물유화제물질의 생성 및 그 성질을 조사하여 본 결과 유화제물질은 hexadecane oil 배지를 사용하여 18$^{\circ}C$에서 대수증식기 중기때에 가장 많이 생성되었다. 그리고 이는 양이온성의 peptidolipid 물질인 것으로 여겨지며 원유와 몇 종의 식용유에도 강한 유화안정능력을 보였다.

• 약학회지
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• 제28권1호
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• pp.11-16
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• 1984

As main index of petroleum pollution in the marine organisms n-, iso-paraffins were purified with clean-up method and measured by FID-GC. Ten species of fishes from the near seas of Korea were employed for the study. n-Heptadecane was detected in most fishes. n-Hexadecane and n-octadecane of n-paraffins were highly accumulated in four species of fishes(Seriola quinqueradiata, Sardinia melamosticta, Clupanodon punctatus and Stromateoids argentus), also n-tetradecane and n-hexadecane accumulated in Cololadis saira. Remarkable peak pattern of n-paraffins was not observed in other fishes. Pristane of iso-paraffins was detected in four species of fishes (Sardinia melamosticta, Clupanodon punctatus, Stromateoides orgentus and Cololadis saira).

• 한국동물학회:학술대회논문집
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• 한국동물학회 1997년도 한국생물과학협회 학술발표대회
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• pp.141.2-141
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• 1997

No Abstract, See Full Text

• 폴리머
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• 제28권1호
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• pp.10-17
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• 2004

폴리(비닐 아세테이트) (PVAc) 나노입자는 공유화제로 헥사데칸을 사용한 수중유형 미니유화 중합법을 이용하여 제조하였고, 제조 조건에 따른 나노입자는 약물 전달체로서의 가능성을 고찰하였다. 제조된 나노입자의 형태를 SEM으로 관찰하였고, 평균 입자크기와 입자의 분포는 입도 분석기로 측정하였다. 또한 항생제와 함께 제조된 PVAc 나노입자에 대한 항생제의 함입은 FT-IR의 CHO, C=O 그리고 OH 피크로서 확인하였다. 실험 결과, 단량체 입자의 크기는 균일화 속도 및 유화제와 공유화제의 양에 의하여 조절할 수 있었고, 제조된 고분자 라텍스의 입자크기는 80∼300 nm의 분포를 나타내었다. 또한 공유화제를 사용한 미니유화 중합방법은 전통적인 에멀젼 제조 방법과 비교하여 균일하고 안정한 단량체 입자가 형성되는 것을 확인할 수 있었다. 이는 헥사데칸을 공유화제로 사용함으로써 단량체 입자간의 오스트발드 숙성과 유착을 방지 또는 지연시키기 때문인 것으로 판단된다.

• 대한수의학회지
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• 제39권3호
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• pp.554-559
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• 1999

The purpose of this study was to evaluate effect of chitosan-oligosaccharides (CHIOL) on hydrophobicity of pathogenic E coli including a field isolate from suckling piglet with diarrhea, E coli-O157 : H7, and E coli-O149 : K88ac. E coli field isolate appeared adhesion of 100% to n-hexadecane between 0.00125% and 0.05% CHIOL. E coli-O157 : H7 occurred adhesion of 69% and 64% under the level of 0.00125% and 0.025% CHIOL, respectively. E coli-O149 : K88ac showed adhesion of 100% in higher than 0.025% CHIOL. For cationic action, the adhesion of E coli isolate and E coli-O149 : K88ac to n-hexadecane were inhibited at level of higher than 10mM $Ca^{2+}$ but did not induce any difference among the concentrations used(p < 0.01). However, the adhesion of E coli-O157 : H7 to n-hexadecane was inhibited at level of higher than 50mM $Ca^{2+}$. In a field trial, control piglets showed average mortality of up to 58% during 3 days after the onset of diarrhea. In contrast, the prevalence of E coli-induced diarrhea in CHIOL-treated groups without mortality was dropped down to average 34% on the 1st day after the treatment of CHIOL, and average 2% on the 4th day. After then, piglets with diarrhea was not present. In conclusion, the low concentrations of CHIOL were most likely to associate with the enhancement of hydrophobicity to pathogenic E coli. Calcium inhibited the hydrophobicity of E coli by CHIOL. These results suggested that CHIOL could be played an efficient and reliable role in treating enteric colibacillosis of piglets.