• Horticultural Science & Technology
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• v.33 no.6
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• pp.820-828
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• 2015

This study was carried out to determine the effects of vernalization, temperature, and soil water deficit (SD) on mesophyll cells, growth, and yield of Chinese cabbage (Brassica campestris L). The palisade parenchyma and spongy tissues of Chinese cabbage were observed under full irrigation and two weeks of SD treatment. These cells were severely collapsed by four weeks SD treatment. The SD treatment had the greatest influence on the growth of Chinese cabbage among the tested treatment factors (vernalization, temperature, and SD), growth significantly decreased by severe drought treatment (four weeks SD treatment). In addition, the relative growth rate, unit leaf rate, leaf area ratio, specific leaf area, and leaf weight ratio were significantly affected by SD treatment; however, other individual factors and their combined treatments did not influence the analyzed growth parameters. The yield under vernalization after high temperature and full irrigation treatments was 3,056 kg/10 a, which was the greatest among all the tested treatments, while four-week SD treatment significantly reduced the yield. Head formation of Chinese cabbage was not altered under SD treatment, and vernalization treatments did not induce bolting. Our results indicated that collapsing mesophyll cells and reduced growth and yield were induced by SD treatment. Thus we suggest that optimal irrigation system should be install to avoid or overcome crippling drought conditions in the open field.

• Advances in Traditional Medicine
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• v.6 no.1
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• pp.1-11
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• 2006

Herbal medicines are widely used for centuries to treat illness and improve health in Asia and the use of these remedies has become a worldwide form of alternative therapy. However, there is very limited evidence from randomized controlled trials to support the efficacy of the vast majority of herbal products. Of the commonly used herbal medicines, systemic clinical experiences and promising experiments in animals have found potential evidence of efficacy for six herbal medicines (Unkei-to, Hachimijio-gan, Keishi-bukuryo-gan, Toki-shakuyaku-san, Shakuyaku-kanzo-to, Sairei-to) in the treatment for female reproductive dysfunction. Because herbs may contain potent bioactive substances, the physician should have an opportunity to outline more stringent regulation, similar to over-the counter drug.

• Journal of Oriental Neuropsychiatry
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• v.15 no.1
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• pp.239-246
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• 2004

Attention Deficit Hyperactivity Disorder(ADHD) is a common disease in children. This study is clinical case reports of 3 ADHD Children treated with acupuncture and herbal medicine. Two boys-one was 10 years old and the other was 8, and one girl-8 years old were treated with acupuncture and herbal medicine from March 2003 to May 2004. Acupoints-CV20(百會) CV24(上星) L7(列缺) LI4(合谷) Liv3(太衝) K3(太谿) was used and herbal medicine-Yukmijihwangtang(六味地黃湯) and Guibitang(歸脾湯) was used. T-score in ADS test(Continuous Performance Tests) checked after these treatments was lowered to the normal range, Conners' parent rating scale and Home Situations Questionaire score were lowered compared with those checked bfore treatment. These result suggest that acupuncture and herbal medicine could be one of helpful treatment to the ADHD children.

• Journal of Acupuncture Research
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• v.19 no.4
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• pp.112-123
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• 2002

Objective : This study was designed to find out the effects of Carthami-Flos herbal acupuncture theraphy on neck pain due to soft tissue damage. Methods : This study was carried out for 34 patients who had neither structural defectiveness of cervical spine nor neural injury but simple soft tissue damage among poeple who visited Hye-dang Oriental Hospital from December 1, 2001 to June 15, 2002. Group A of 17 patients was taken Carthami-Flos herbal acupuncture treatment. Group B of 17 patients was taken common acpuncture treatment. Results : We have found out the good effects of Cathami-Flos herbal acupuncture on the patients due to soft tissue damage. Conclusion : The Carthami-Flos herbal acupuncture treatment is useful on the patients of neck pain due to soft tissue damage.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.4
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• pp.1228-1231
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• 2004

There are little report on treatment of compression fracture with Traditional Korean Acupuncture Therapy. We suggest to treat Lumbar compression fracture with the SAAM(사암) Acunpture, Carthami-Flos Herbal Acupuncture Therapy. The Treatment methods of the SAAM(사암). Acnpucture, Eliminating extravasated Blood, was apllied at SP3, LU9, LI11 and Carthami-Flos Herbal Acupuncture at the waist. We treated the patient who was diagnosed as lumbar compression fracture by MRI. After 15 days of Treatment, SAAM Acupuncture and Carthami-Flos Herbal Acupuncture, a remarkable improvement was made for Lumbar compression fracture. There was reports about SAAM Acupuncture and Carthami-Flos Herbal Acupuncture of Patient with Lumbar Compression Fracture. It is very effective to reduce the pain and shortening the period of therapy.

• Journal of Pharmacopuncture
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• v.4 no.2
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• pp.57-63
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• 2001

Objectives : The Purpose of this study was to evidence the effect of Herbal Acupuncture therapy(Sangsik no.1) by comparing body fat and obesity degree of Group B(group of Herbal acupuncture therapy and general obesity treatment) with Group A(group of non-Herbal acupuncture therapy and general obesity treatment) in twenty four patients who have received OPD treatment at Sang Ji oriental medical hospital and chiefly diagnosed obesity from June 2000 to September 2001. Methods : We checked the change of Obesity degree with Inbody 3.0. Results and Conclusions : Two groups were no significance, but remarkably showed a significant decrease in Percent Body Fat. According to the above results, it is considered that Herbal Acupuncture therapy(Sangsik no.1) showed a significant decrease in Percent Body Fat, but Others were no significance.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.5
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• pp.1285-1289
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• 2006

Hominis placenta (HP) has been used as an agent for promoting physiological function in traditional asian medicine. The present study was peformed to investigate whether HP acupuncture treatment in an experimental tumor mice model inhibit tumor growth through immunomodulatory effects. Mice were inoculated subcutaneously with colon26-L5 cells on the back. Three days after tumor inoculation, HP herbal acupuncture treatment was conducted on BL18 acupoint every other day for three weeks. HP Herbal acupuncture treatment significantly suppressed the primary tumor growth and prolonged survival rate. To evaluate immunomodulatory effect of HP acupuncture, splenocytes proliferation assay, fluorescence-activated cell sorting (FACS) and ELISA for IFN- ${\gamma}$, and IL-4 cytokine level. HP herbal acupuncture enhanced the mitogenic activity of Balb/c whole splenocytes induced by various mitogenic stimuli and increased immune cell population such as T cell, B cell, Th cell, Tc cell and Macrophages. HP herbal acupuncture caused a marked increase of production of Th1 cytokine (IFN- ${\gamma}$ ,) and decrease of production of Th2 cytokine (IL-4). These results indicated that HP herbal acupuncture suppresses tumor growth through a mechanism leading to a Th1 dominant immune state.

• Herbal Formula Science
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• v.29 no.3
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• pp.147-153
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• 2021

Ulcerative colitis (UC) is one of inflammatory bowel diseases (IBD) with unknown etiopathogenesis. This case report details remission of UC induced by Korean herbal medicine treatment. A 31-year-old male patient diagnosed as UC after a series of examinations including endoscopy and fecal calprotectin (FC) test. He had severe bloody diarrhea over 10-20 times a day despite taking 5-aminosalicylic acid and steroid. He was given individualized Korean herbal medicine Dowha-tang according to pattern identification. After taking Dowha-tang for 7 months, clinical remission was achieved. The symptoms disappeared and FC level went down to normal level. No adverse events were reported. This case report shows that Korean herbal medicine treatment may have the potential for clinical remission of UC. Further investigation is warranted.

• Journal of Oriental Neuropsychiatry
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• v.33 no.2
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• pp.181-214
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• 2022

Pediatric epilepsy, a chronic, recurrent brain disorder, is the most common neurological disorder in children. Its prevalence is increasing. Early management is very important since 30~40% of cases persist into adulthood. To provide basic data for future clinical research on pediatric epilepsy using Korean medicine treatment and cooperation between Western medicine doctors and Korean medicine doctors, we reviewed recent clinical research in traditional Chinese medicine (TCM) using herbal medicine for pediatric epilepsy. A total of 23 articles (1 clinical practice guideline, 3 systematic reviews, 15 randomized controlled trials (RCTs), and 4 non-RCTs) were reviewed in this study. The authors summarized characteristics of included studies regarding study subjects, diagnostic tools, pattern identification tools, treatment period, evaluation tools, detail of herbal medicines, treatment effects, and adverse events. Combination therapy using both herbal medicine (HM) and anti-epileptic drugs (AEDs) was performed more frequently than herbal medicine alone. Liver-pacifying medicinal, water-draining medicine, and orifice-opening medicine were frequently used. The main single HMs were Cheonma, Boglyeong, Jogudeung, and Seogchangpo. Combined therapy using HM and AEDs had significant benefits in improving total effective rate. It also appeared to be safer than AEDs. However, since the quality of clinical trials was poor and only studies in the last 10 years were included, the clinical evidence was uncertain. Finally, the authors provided limitations of this study and several suggestions for future research based on our analysis results.

• The Journal of Internal Korean Medicine
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• v.44 no.6
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• pp.1176-1185
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• 2023

Introduction: Non-erosive reflux disease (NERD) is the most common subtype of gastroesophageal reflux disease (GERD). This study aims to synthesize evidence on the efficacy and safety of various herbal medicines for the treatment of NERD. Methods and analysis: Ten electronic databases will be examined: MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials, Embase, Allied and Complementary Medicine Database, China National Knowledge Infrastructure Database, Citation Information by Nii, Korean Medical Database, Korean Studies Information Service System, National Digital Science Library, and Oriental Medicine Advanced Searching Integrated System. All randomized controlled trials published from inception to May 2023 that meet the eligibility criteria will be selected. Two independent researchers will extract data, such as publication year, study design, intervention details, outcome measures, main results, and adverse events. The risk of bias and quality of evidence will be assessed, and subgroup analyses will be performed according to the type of control intervention and herbal medicine. The analysis process will be conducted using Review Manager 5.4 software. Discussion: This review will present a summary and rationale for herbal medicine's effectiveness in treating NERD. The findings of this review can help those who want to apply herbal medicine to the treatment of NERD.