• 제목/요약/키워드: Herbal medicine safety

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Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

  • Kamau, Loice Njeri;Mbaabu, Peter Mathiu;Mbaria, James Mucunu;Gathumbi, Peter Karuri;Kiama, Stephen Gitahi
    • 셀메드
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    • 제6권3호
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    • pp.21.1-21.15
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    • 2016
  • In Kenya, traditional knowledge on herbal medicine has remained a mainstream source of maintaining wellbeing for generations in many communities. However, the knowledge has been eroded in the course of time due to sociocultural dynamics virtually advanced by Christianity and formal education especially in the Kikuyu community. The study documented current ethnobotanical knowledge and threat to the traditional knowledge on medicinal plants among the Kikuyu community. A survey was carried out in Mathira, Tetu, Kieni, Othaya, Mukurweini, and Nyeri Town constituencies. Thirty practicing herbalists were purposively sampled; 5 per constituency. Data was obtained through semi - structured questionnaires and analyzed both qualitatively and quantitatively. A total of 80 ailments treated using 111 medicinal plant species distributed within 98 genera and 56 families were documented. Prevalent communicable diseases treated using herbal medicine included; gonorrhea (17.5%), malaria (15%), respiratory infections (12%), colds (10%) and amoebiasis (10%). Non-communicable diseases were; joint pains (11.1%), ulcers/hyperacidity (8.7%), high blood pressure (8.7%), intestinal worms (11.1%) and arthritis/gout (10%). Frequently harvested plant materials were; roots, barks and leaves. The study concluded that, traditional medicine practitioners in Nyeri County possessed wide knowledge of herbal medicine but this knowledge was on the verge of disappearing as it was largely a preserve of the aged generation. The study recommended massive campaign about the benefits of using herbal medicine in the study area. Further pharmacological studies are recommended on the mentioned plant species aimed at establishing their efficacy and safety as well as standardization as potential drugs.

노봉방에서 추출된 카페인산 페네틸 에스테르가 함유된 한방화장품의 미백 개선에 관한 임상적 연구 (A Clinical Research about Herbal Cosmetics Containing Caffeic acid phenethyl ester Isolated from Vespae Nidus on the Whitening Effects)

  • 차호열;김희연;하기태;천진홍;김기봉
    • 대한한의학회지
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    • 제38권3호
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    • pp.86-95
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    • 2017
  • Objectives: The purpose of this clinical research was to investigate the effects of herbal cosmetics containing Caffeic acid phenethyl ester (CAPE), an ingredient compound of various herbs including Vespae Nidus, on the Whitening Effects. Methods: A total of 20 subjects who visited Pusan National University Hospital from March 2nd, 2017 to April 11th, 2017 were included. In this study, we evaluated the visual evaluation, the melanin index (M) and erythema index (E) through skin analysis equipment, the subjective whitening improvement analysis, and the adverse reaction according to product use. Statistical analysis was performed with independent t-test and Mann-Whitney's U test. Statistical significance was achieved if the probability was less than 5% (p<0.05) Results: As a result of the visual evaluation, it was effective in improving skin whitening. The subjective whitening improvement analysis also showed positive results. However, no statistically significant differences were found between the test and control cosmetics in the melanin index (M) and erythema index (E) through skin analysis equipment. In the safety evaluation, some adverse reactions were reported, but no significant were observed directly from cosmetics. Conclusions: Considering the above results, we have confirmed the possibility of herbal cosmetics containing containing CAPE of Vespae Nidus Extracts.

임신 중 교통사고 환자의 한방치료에 대한 일반인 인식조사 (A Survey on the General Public's Perception of Korean Medicine Treatment for Traffic Accident Patients during Pregnancy)

  • 황보경;정우진;남궁진;김수덕;박미소;구승혁;김성현;문현우;백혜경;정재중
    • 대한한방부인과학회지
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    • 제35권4호
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    • pp.19-36
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    • 2022
  • Objectives: This study was conducted to find out the general public's perception of Korean Medicine (KM) treatment for traffic accident (TA) patients during pregnancy. Methods: A self-developed questionnaire was distributed to outpatients and inpatients between the ages of 19 and 70 at KM hospitals located in Bucheon. The subjects were asked whether they thought KM treatment could be applied to TA patients during pregnancy. The perceptions of acupuncture, pharmacupuncture, herbal medicine, and Chuna treatment during pregnancy were also investigated. Results: 87.50% answered that KM treatment could be applied to TA patients during pregnancy. Most respondents thought that musculoskeletal symptoms of TA could be treated with KM (85.71%). 93.75%, 87.50%, 56.25%, and 52.08% of the respondents said they were willing to recommend acupuncture, pharmacupuncture, herbal medicine, and Chuna treatment to patients after TA during pregnancy. The respondents answered that acupuncture (95.83%), pharmacupuncture (91.67%), herbal medicine (62.50%), and Chuna (66.67%) is effective for pain controlling during pregnancy, and acupuncture (8.33%), pharmacupuncture (12.50%), herbal medicine (45.83%), and Chuna (39.58%) could be affect the risk of premature birth, miscarriage or birth defects. Conclusions: Acupuncture and pharmacupunture treatment are perceived positively, whereas herbal medicine and Chuna treatment are perceived negatively by the general public for the TA patients during pregnancy. In order to establish the correct awareness of KM treatment for TA patients during pregnancy, more clinical studies and case reports on the efficacy and safety of KM treatment during pregnancy are required.

The Effects of Injincheonggan-tang on Two Patients with HBeAg-Negative Chronic Hepatitis B : Case Report

  • Jang, Eun Gyeong;Kim, Young Chul;Woo, Hong Jung;Lee, Jang Hoon
    • 대한한의학회지
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    • 제35권2호
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    • pp.69-78
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    • 2014
  • Objectives: This case report was executed to confirm the efficacy and safety of Injincheonggan-tang on two patients with HBeAg-negative chronic hepatitis B. Methods: We reviewed the changes of clinical progress and laboratory records of patients with chronic hepatitis B who did not want to take any antiviral or interferon therapy. One patient has visited the department of internal medicine I of Kyung Hee University Korean Medicine Hospital, from October 2010 and the other, from October 2006. Both of them were prescribed with Injincheonggan-tang and laboratory tests were conducted as well. Results and Conclusions: AST, ALT and HBV DNA which are significant indicators of liver function were controlled in the normal range during the herbal treatment period and subjective clinical symptoms were also improved after taking Injincheonggan-tang.

대체의학에서 갱년기 증후군에 사용되는 약물에 대한 고찰 (Review of Herbs Used as Treatment for Menopausal Patients in Alternative Medicine)

  • 김승현;이진무;이창훈;조정훈;장준복;이경섭
    • 대한한방부인과학회지
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    • 제21권3호
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    • pp.90-98
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    • 2008
  • Purpose: Menopausal syndrome is caused by urgent changes of sex hormone in women. The hormonal therapy can soothe the problems of menopausal patients, but it can increase the probability of another disease, such as breast cancer, heart attack, etc. So the demand of alternative herb therapy is increasing in Western countries. In Korea, herbal medicine is imported and used by Western doctors. To know and use the alternative herbal medicine, Korean Medical doctors should know their efficacy and safety. Methods: We researched the Medline(Pubmed) with the key word such as 'CAM', 'herb' and 'menopause'. We selected the herbs known as treating the menopausal syndrome and researched the similar or same herbs that are used in Korean medicine by the scientific name and efficient ingredients. To evaluate the efficacy of the herbs, we compared the herbs that were differently defined in alternative and Korean medicine Results: Balm, black cohosh, chaste berry, dong quai. evening primrose oil. ginkgo, St. John's wort, valerian root, and sarsaparilla were chosen as prevalent herbs used in alternative medicine. The pharmacologic effect of Black cohosh, licorice root, St. John's wort were recognized. But these three herbs are not usually prescripted for menopausal patients in Korean medicine. So we could apply these three herbs as one of Korean medical treatments. The efficacy of other herbs cannot be surely prescripted for menopausal patients. Conclusion: The efficacy and safety of alternative medicine is not proved yet. But to diversify the treatmental methods of Korean medicine, we need to prove and use these medicine as one of Korean medical treatment.

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10년간 국내 양방 의학 학술지에 게재된 한방치료 부작용 사례 고찰 (A Study on Korean Traditional Medicine Side Effects Cases Described in Domestic Western Medical Journals in the Past 10 Years)

  • 이명화;손변우;김경민;전수형;김영균
    • 대한한방내과학회지
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    • 제39권4호
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    • pp.686-698
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    • 2018
  • Objectives: The aim of this study was to report the current status of the Korean traditional medicine side effects described in domestic western medical journals in the past 10 years. Methods: We searched for domestic western medical papers about Korean traditional medicine side effects cases from January 1, 2008, to August 31, 2017. Results: Thirty papers were selected from 31 studies. The number of papers of side effects caused by acupuncture was 21 (70%), by herbal medication was 7 (23%) and by thread lifting was 2 (7%). The number of papers of side effects caused by Korean medical doctors was 20 (66.8%), by non-medical persons including patients was 2 (6.6%), by herbal pharmacists was 1 (3.3%), by multiple practitioners, including Korean medical doctors, was 1 (3.3%), and by unknown persons was 6 (20%). Reported side effects were mostly mild, except for death and severe side effects. Conclusions: Studies of Korean traditional medicine side effects are short, and in-depth studies of stability are needed. These studies will improve the safety of the Korean traditional medicine.

임신 중 교통사고의 한의학적 치료에 대한 연구동향 분석 (Research Trends of Korean Medicine Treatment for Traffic Accidents during Pregnancy)

  • 김남훈;황덕상;이진무;이창훈;장준복
    • 대한한방부인과학회지
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    • 제32권3호
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    • pp.73-85
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    • 2019
  • Objectives: The purpose of this study was to analyze efficacy and safety of Korean Medicine treatment for traffic accidents during pregnancy. Methods: We investigated the studies on Korean Medicine treatment for traffic accidents during pregnancy via searching through PUBMED, the Cochrane Library, CNKI, and domestic search engines and a total of 6 studies were selected. Results: The major complaints of traffic accidents during pregnancy were low back pain, neck pain and gastrointestinal symptoms. And there were vaginal bleeding and pruritus vulvae in the complaints. All of the studies were given acupuncture treatment for symptom relief, and chuna, herbal acupuncture and cupping were administered. Herbal medicine was also performed, and the most prescribed herbal medicine was Antaeeum-gamibang. All cases reported as traffic accidents during pregnancy showed a reduction in symptoms, normal pregnancy maintenance and delivery, and no miscarriage were reported. Conclusions: Korean Medicine treatment is an effective and safe treatment option for traffic accidents during pregnancy. Further systematic studies are needed to establish the basis for Korean Medicine treatment for traffic accidents during pregnancy.

충북지역 소아 청소년 한의 치료에 대한 인식 및 만족도 조사 - 보호자 대상 설문 연구 (A Survey on the Perception and Satisfaction of Korean Medicine in Children and Youth in Chungcheongbuk-do - A Survey of Parents)

  • 김태정;성현경
    • 대한한방소아과학회지
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    • 제37권4호
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    • pp.15-24
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    • 2023
  • Objectives This study aimed to identify the current status and satisfaction with Korean medicine treatment and analyze the perceptions of parents about Korean medicine treatment in children. Methods A Web survey (Moaform) was conducted with 52 parents whose children used Korean medicine and 53 parents who did not. We investigated the reasons why the user group chose treatment and satisfaction with each treatment and why the non-user group did not choose the treatment. Results Children in the user group were frequently prescribed herbal medicines (decoctions) and acupuncture. However, they showed low satisfaction in terms of fear of acupuncture and dissatisfaction with the unique taste of herbal medicine. Non-user parents had a favorable opinion of Korean medicine, but had relatively negative perceptions about whether their children were willing to visit in the future. Conclusions Parents who used Korean medicine for their children had positive perceptions and trust in Korean medicine. However, those who did not use Korean medicine were concerned about the safety and potential harm of its application to their children.

사상의학적 중풍 후유증 치료에 대한 체계적 문헌 고찰 (A Systematic Review on the Treatment of Post-Stroke Patients Based on Sasang Constitutional Medicine)

  • 오현주;이정윤;이혜리;이준희
    • 사상체질의학회지
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    • 제34권2호
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    • pp.48-64
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    • 2022
  • Objectives The purpose of this study was to review and evaluate the clinical evidence of the efficacy and safety of treatment based on Sasang constitutional medicine (SCM) for post-stroke patients by systematic review and meta-analysis. Methods Randomized controlled trials (RCTs), published in 10 electronic databases up to December 2020, were searched. For the included studies, Cochrane's risk of bias assessment was performed to analyze the methodological quality. The strength of evidence was evaluated using the grading of recommendations assessment, development, and evaluation system based on the results of analyses. All review processes were performed by two independent researchers. Results Five RCTs were finally included. All included RCTs were conducted for one month on post-stroke patients in 60-80s, four studies on Tae-Eum patients and one study on So-Yang patients. Four types of constitution-specific herbal medicine (Chungpyesagan-tang, Cheongsimsanyak-tang, Yeoldahanso-tang, and Yangkyuksanhwa-tang) and constitution-specific acupuncture therapy were identified as interventions. More than half of the included studies were evaluated as low quality due to the high-risk of bias in selection, performance, and detection. The combination of constitution-specific herbal medicine, acupuncture, and conventional treatment was more effective in improving the patients' motor impairment, dysphagia, aphasia, and depression than conventional treatment alone. No serious adverse events by SCM treatment were reported. Conclusions SCM treatment may improve the sequelae of post-stroke patients safely in combination with conventional treatment. Since the quality of clinical evidence included in this study was low, higher quality clinical evidence obtained in well-designed clinical studies will be needed.

일개 보건지소에 내원한 급성기 후 코로나-19 환자들의 특성 및 한의 치료 효과 분석: 사례군 연구 (Effects of Korean Medicine Treatment at Public Health Center for Post-acute COVID-19 Patients: A Retrospective Case-series of 11 patients)

  • 유창환;김관일;정희재;이범준
    • 대한한의학회지
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    • 제44권2호
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    • pp.132-148
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    • 2023
  • Objectives: The purpose of this study is to determine the clinical features of post-acute COVID-19 syndrome and the effectiveness and safety of Korean medicine treatment at the Public health center. Methods: The study was conducted among 11 patients with post-acute COVID-19 syndrome who attended a single public health center from January to December 2022. We retrospectively analyzed the charts of 11 patients and collected clinical characteristics, previous treatments, Korean medicine treatments, outcome variables (Numeral Rating Scale (NRS), Leicester Cough Questionnaire (LCQ), Visual Analog Scale (VAS)), adverse events, etc. Results: Of the 11 patients, six were women, and the average age of all patients was 68.27±12.31 years. The most common symptom were cough(n=9, 81.82%) and sore throat(n=9, 81.82%), followed by sputum, fatigue, rhinorrhea, and loss of appetite, etc. All 11 patients were treated with herbal medicine, with Samso-eum(n=6, 54.55%), Yeonkyopaedok-san(n=5, 45.45%), and Haengso-tang(n=3, 27.27%) being the most commonly used. After herbal medicine treatment, the median cough NRS decreased from 5 to 1, and the median sore throat NRS decreased from 4 to 1, both of which were statistically significant. One patient reported adverse event of dyspepsia and heartburn, but it was mild. Conclusions: The study presented the clinical features of the post-acute COVID-19 syndrome and suggested that Korean medicine treatment at public health centers may be effective and safe in alleviating associated symptoms.