• 대한한의학방제학회지
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• 제14권1호
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• pp.176-183
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• 2006

Purpose: The purpose of this case study is to report the effect of oriental and western medicine combination therapy for the Asthma during the period of pregnancy. Methods: We treated the patient who had the Asthma during the period of pregnancy and visited Dongshin University oriental hospital. The patient in this case was admitted for 9days due to the Asthma on the twenty-third week period of pregnancy. In consideration of pregnancy, this patient was treated with oriental and western medicine combination treatments such as herb medicine, acupuncture, herbal acupuncture therapy, and so forth. Results: There was remarkable improvement in condition of the patient, treated by oriental and western medicine combination therapy. Conclusion: We confirmed that western medicine treatment is effective in curuing with an urgent symptoms, but there is a limit to complete recovery or prevention. On the other hand. it proves that oriental medicine treatment is proficient with continuous treatment effect, but further studies are needed.

• 대한한방부인과학회지
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• 제36권1호
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• pp.1-22
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• 2023

Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of herbal medicine treatment on Antiphospholipid antibody positive recurrent abortion. Methods: We searched for randomized controlled trial of last 20 years based on Antiphospholipid antibody positive recurrent abortion and herbal medicine. The paper search was conducted through 7 online databases on July 16, 2022. Results: 9 studies were selected after selection and exclusion criteria. 5 studies compared combined treatment of herbal and western medicine, with western medicine alone. 4 studies compared herbal medicine alone with western medicine. Comparing with control group, the treatment group showed much improvement on conversion rate of anti-phospholipid antibodies, serum hCG and progesterone levels, pregnancy duration or fertility rates, and various symptoms. Conclusions: In this study, we found out benefit of herbal medicine with Antiphospholipid antibody positive recurrent abortion. For reliable evidence, further research is needed to establish safety of herbal medicines, standardize symptom criteria and specify the treatment course.

• 대한융합한의학회지
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• 제5권1호
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• pp.5-23
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• 2023

Objectives: This study was conducted to evaluate the effect of combination treatment of herbal medicine for external use and western medicine for atopic dermatitis (AD). Methods: We searched randomized controlled trials (RCTs) which assess the effect of combination treatment of herbal and western medicine for AD through 8 electronic databases from the start to December 2022. The data synthesis was conducted by using Review Manager (RevMan, ver.5.4.1) and Cochrane risk-of-bias tool was used to evaluate the risk of bias. Results: 13 RCTs were included. The combination treatment group had significantly higher total efficacy rate(p<0.0001) and lower SCORAD score (p<0.00001) than the western medicine treatment group. The adverse event rate was also significantly lower in the combination treatment than the western medicine treatment group (p<0.0001). But there was no significant difference in recurrence rate (p=0.09). Conclusion: This study demonstrates that the combination treatment of herbal and western medicine could be safe and effective for AD. However, due to limits of included studies such as high heterogeneity between the literature and unclear risk of bias, further studies are warranted.

• 대한한방소아과학회지
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• 제35권4호
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• pp.56-74
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• 2021

Objectives The purpose of this study is to analyze the trend of herbal medicine treatment, treatment's effect and stability for Crohn's disease by reviewing clinical studies published over the past 5 years. Methods 22 articles which were published from 2017 to August, 2021 were obtained from the ScienceON, Research information sharing service (RISS), Koreanstudies Information Service System (KISS), Oriental medicine advanced searching integrated system (OASIS), China national knowledge infrastructure (CNKI), Pubmed. We analyzed the literature in regards to the treatment methods and results. Results There were 6 case reports, 1 controlled clinical trial, and 15 randomized controlled trial and in most cases, herbal medicines and Western medicines were administered in combination. The pathology of damp-heat due to spleen deficiency was the most common, and Sijunzi-tang and Shenling Baishu san were the most commonly used. As a result of the treatment, it was found that the combined administration of the herbal medicine and the Western medicine was more effective than the administration of the Western medicine alone. Conclusions Herbal treatment of Crohn's disease induced high cure rate safely than when only western treatment was applied. Future studies on safety and studies that can suggest specific guidelines for the combined administration of western and herbal medicines are needed.

• 동의신경정신과학회지
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• 제31권4호
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• pp.301-314
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• 2020

Objectives: The purpose of this study was to provide clinical evidence to support the use of herbal medicine combined with western medicine for BPSD. Methods: Studies were identified by searching CNKI, Pubmed, EMBASE, Cochrane Library, SCIENCEON, RISS, KMbase, KISS, OASIS. Literature searches of Chinese, English, and Korean databases were performed. Two authors independently extracted the data and evaluated the quality of each study. Results: The literature search identified 203 articles. Of these, 7 were selected for the analysis. The risk of bias in most studies was unclear. The most frequently used diagnostic tools were the NINCDS-ADRDA and DSM-IV. The most commonly used results indicator was NPI. In 6 of the 7 papers, combination treatment (herbal & Western medicine) was statistically significantly more effective than single treatment (Western medicine alone) for BPSD. No significant adverse events were reported. Conclusions: Herbal medicine in combination with Western medicine is more effective for treating BPSD than Western medicine alone. However, the quality of the studies used in this study was uncertain and the sample size was too small. Based on the findings of this study, more high-quality clinical trials are needed to confirm the efficacy of combination treatment.

• 대한중풍순환신경학회지
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• 제10권1호
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• pp.27-32
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• 2009

Object : The purpose of this study was to evaluate whether herbal medication may injure the liver function and kidney function in stroke patients. Method : We observed the serum AST, ALT, r-GTP, Creatinine, BUN of 78 patient from May 1. 2008 to June 30. 2009 admitted in Oriental Hospital of Daejeon University. Liver function and Kidney function tests were done on admission and before discharge. And all patients take herbal medicine with Western medicine. Result : AST, ALT, r-GTP, Creatinine, BUN decreased on discharge compared with the value on admission. The liver function and kidney function test score(AST, ALT, r-GTP, Creatinine, BUN) by administration period of herbal medication was not significantly changed. Conclusion : This study suggests that general herbal medication does not injure liver function and kidney function of human.

• 대한한의학회지
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• 제42권1호
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• pp.99-109
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• 2021

Objectives: Objective: The purpose of this study is to investigate the treatment of herbal medicine for patients with COVID-19 asymptomatic infections. Method: In English, search engines such as 'PubMed', 'Science Direct', and 'Cumulative Index to Nursing and Allied Health Literature (CINAHL)' were used. In Chinese, search engines such as 'China National Knowledge Infrastructure (CNKI)' and Wanfang were used. The keywords for the search engines were 'COVID-19', 'asymptomatic infection', 'Korean Medicine', 'traditional Chinese medicine', 'herbal medicine', and etc. Only clinical studies using herbal medicine for patients without fever or respiratory symptoms were selected. We excluded the cases that do not fit the research topic. Results: A total of 5 studies were finally selected. Among them, four of them used integrated herbal medicine and Western medicine, and one of the studies treated exclusively for herbal medicine. There were a total of seven prescriptions for herbal medicine used in the study. Outcome variables were used as following: lab test, nucleic acid conversion time, hospitalization period, chest CT, and etc. In the RCT study, herbal medicine and Western medicine decreased nucleic acid conversion time, average hospitalization time compared to the control group, but it was not statistically significant. No other adverse reactions were reported in all studies. Conclusion: According to the results, integrated herbal medicine and Western medicine might be an effective treatment for patients with COVID-19 asymptomatic infection reducing hospitalization period, time of nucleic acid turning negative. No severe adverse effects were reported. However, it is thought that better-designed research will be needed in the future.

• 대한한방부인과학회지
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• 제33권3호
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• pp.119-135
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• 2020

Objectives: The purpose of this study is to confirm the effectiveness and safety of herbal medicine treatment for treating pregnancy-induced hypertension. Methods: We searched for randomized controlled trials of pregnancy-induced hypertension treated with herbal medicine, through nine databases. Interventions and results of the selected clinical studies were analyzed. Results: Eleven randomized controlled trials were finally included according to the inclusion and exclusion criteria. Treatment group was treated with herbal medicine alone in two studies, and with herbal medicine and western medicine in nine studies. Control group was treated with western medicine. Taxilli Ramulus (桑寄生) (54.5%) was the most frequently used herb in herbal medicine treatment. In all of eleven studies, treatment group was more effective for pregnancy-induced hypertension than the control group. Conclusions: This study suggested that herbal medicine treatment alone or combined with western medicine treatment could be helpful in improving the therapeutic effect on pregnancy-induced hypertension and reducing side effects as well. However, in order to obtain stronger evidence of herbal medicine treatment for pregnancy-induced hypertension, more high-quality and well-designed randomized controlled trials should be conducted.

• 동의신경정신과학회지
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• 제23권4호
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• pp.49-68
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• 2012

Objectives : Recently, the elderly population and dementia prevalence have been rapidly increasing in Korea. Dementia is a concept of syndrome composed of characteristic symptoms. However, there have been no approved treatments for dementia with proven efficacy. Therefore, we investigated Korean traditional treatment being used in clinic and collaborative practice for dementia in the professional group. Methods : We conducted a survey using questionnaires to professors of oriental neuropsychiatry for a month. Items of the questionnaire consisted of overall Korean traditional medical treatment for dementia, which included herbal medicine, acupuncture, moxibustion, cupping, psychotherapy and others. Results : 1. It was shown that Yukmijihwangtanggamibang, Jowiseungcheongtang, Seonghyangjeonggisan have been used the most in herbal medicine. 2. Chechim, Saamchimbeop, and scalp acupuncture have been used the most in acupuncture treatment. 3. In Korean traditional psychotherapy, Ijeongbyeongi, Jieongoronyobeop, Gigongyobeop have been used, and effective in anxiety, agitation, improvement of comprehension for caregiver and environment. 4. Most professors answered that collaborative practice between Korean traditional medicine and western medicine has been needed for dementia. They suggested that herbal medicine, followed by acupuncture, and moxibustion can be used with western medicine simultaneously. Conclusions : The survey revealed that professors use herbal medicine and acupuncture as main treatments for dementia. They share perspective regarding the need of long period to treat dementia patients, and there are needs of collaborative practice for dementia.

• 대한한의학방제학회지
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• 제22권1호
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• pp.193-200
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• 2014

Objective : The purpose of this study is to report that patient diagnosed as drug-induced liver injury treated with herbal and western medicine improve liver function test. Methods : We treated the patient diagnosed as drug-induced liver injury caused by antibiotics with Hepatotonics and Cheonggan-tang Gagam(淸肝湯加減). Then, We followed up the result of liver function test. After the result of liver function test improved, we diagnosed the patient with Korean medical methods, and evaluated the symptom of Cerebral infarction and liver function test treating the patient with Jihwangumja (地黃飮子). Result : After our treatment, Liver function test and symptoms of Cerebral infarction result improved. Conclusion : Use of Western medicine with herbal medicine can improved liver function test of drug-induced liver injury effectively and herbal medicine do not disturb the liver function.