The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Recent Domestic and International Trends in Clinical Research of Herbal Medicine Treatment for Crohn's disease

크론병의 한약 치료에 대한 최근 국내외 임상연구 동향

  • Lee, Shin Hee (Department of Korean Pediatrics, Daegu Korean Medicine Hospital of Daegu Haany University) ;
  • Heo, Yu Jin (Department of Korean Pediatrics, Daegu Korean Medicine Hospital of Daegu Haany University) ;
  • Cho, Yun Soo (Department of Korean Pediatrics, Daegu Korean Medicine Hospital of Daegu Haany University)
  • 이신희 (대구한의대학교 부속 대구한방병원 한방소아과) ;
  • 허유진 (대구한의대학교 부속 대구한방병원 한방소아과) ;
  • 조연수 (대구한의대학교 부속 대구한방병원 한방소아과)
  • Received : 2021.10.19
  • Accepted : 2021.11.20
  • Published : 2021.11.30
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Abstract

Objectives The purpose of this study is to analyze the trend of herbal medicine treatment, treatment's effect and stability for Crohn's disease by reviewing clinical studies published over the past 5 years. Methods 22 articles which were published from 2017 to August, 2021 were obtained from the ScienceON, Research information sharing service (RISS), Koreanstudies Information Service System (KISS), Oriental medicine advanced searching integrated system (OASIS), China national knowledge infrastructure (CNKI), Pubmed. We analyzed the literature in regards to the treatment methods and results. Results There were 6 case reports, 1 controlled clinical trial, and 15 randomized controlled trial and in most cases, herbal medicines and Western medicines were administered in combination. The pathology of damp-heat due to spleen deficiency was the most common, and Sijunzi-tang and Shenling Baishu san were the most commonly used. As a result of the treatment, it was found that the combined administration of the herbal medicine and the Western medicine was more effective than the administration of the Western medicine alone. Conclusions Herbal treatment of Crohn's disease induced high cure rate safely than when only western treatment was applied. Future studies on safety and studies that can suggest specific guidelines for the combined administration of western and herbal medicines are needed.

Keywords

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