• Journal of Pharmacopuncture
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• v.23 no.2
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• pp.62-70
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• 2020

Coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). Currently, the management of patients with COVID-19 depends mainly on repurposed drugs which include chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β and others. In this review, the potential of Nigella sativa (black cumin seeds) to treat the patients with COVID-19 analyzed, as it has shown to possess antiviral, antioxidant, anti-inflammatory, anticoagulant, immunomodulatory, bronchodilatory, antihistaminic, antitussive, antipyretic and analgesic activities. Medline/PubMed Central/PubMed, Google Scholar, Science Direct, Directory of open access journals (DOAJ) and reference lists were searched to identify articles associated with antiviral and other properties of N.sativa related to the signs and symptoms of COVID-19. Various randomized controlled trials, pilot studies, case reports and in vitro and in vivo studies confirmed that N.sativa has antiviral, antioxidant, anti-inflammatory, immunomodulatory, bronchodilatory, antihistaminic, antitussive activities related to causative oraganism and signs and symptoms of COVID-19. N. sativa could be used as an adjuvant therapy along with repurposed conventional drugs to manage the patients with COVID-19.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.2
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• pp.76-90
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• 2015

Objectives : This study were invesitigated papers published in international journals to assess the effect of Korean Medicine treatments for menopausal depression. Through this review, we aimed to research more effective ways of menopausal depression treatment. Methods : The database of this review was created through searching PubMed from Jan, 2005 to Feb, 2015 : using terms of ‘menopausal depression’ and ‘post menopausal depression’ with ‘acupuncture’, ‘alternative medicine’, ‘CAM’ and ‘herbal medicine’. Results : 119 studies were analyzed but some of them were excluded due to lack of relevance or noncomformity of subjects. Finally, 16 studies were included in this review. Conclusions : In 16 studies, the acupuncture and herb decoction had significant interventions to improve menopausal depression. Therefore Acupuncture and herbal medicine may be effective treatment method of menopausal depression.

• Journal of Korean Medicine for Obesity Research
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• v.19 no.1
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• pp.56-67
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• 2019

Objectives: The purpose of this study is to review clinical studies of herb medicine and acupuncture treatment on obesity in menopausal women. Methods: Key words "Obesity", "Menopause", "Herb medicine", "Acupuncture", "Moxibustion", "Catgut embedding" were searched on 9 database systems (PubMed Central, Cochrane Controlled Register of Trials, Embase, China Academic Journals, Korean Traditional Knowledge Portal, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, National Digital Science Library, DBpia) on April 30th 2019. Results: 1 case report and 17 clinical trials were collected in accordance with the selection and exclusion criteria. Among the 17 trials, 6 were randomized controlled trials, 1 was controlled clinical trial, and 10 were single-arm trials. The types of intervention were herb medicine, electroacupuncture, acupuncture, auricular acupuncture, warm needle acupuncture, moxibustion, laser acupuncture, and catgut embedding. The study design, study results and method of intervention were analyzed. Conclusions: 1 case report described the effectiveness of pharmacopuncture, 4 trials described the effectiveness of herbal medicine, 2 of electroacupuncture, 1 of laser acupuncture, and 2 of catgut embedding. Among the 17 trials, 2 studies showed that herbal medicine treatment was more effective than no treatment or selective serotonin reuptake inhibitors, and 1 study showed that electroacupuncture was more effective than hormone therapy. All of 18 selected studies reported the effectiveness of weight reduction and abdominal obesity reduction after the traditional Korean medicine treatment for obesity in menopausal women.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.16 no.3
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• pp.260-267
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• 2003

Burn injury is occuring often in our living environment. But there has been little report on the treatment of burn on the basis of Oriental medicine. So we experienced a 53 year old female with second degree burn on the feet and reported the result of the treatment for her with Acupuncture, Herb-med, Negative therapy and Light therapy.

• Journal of Korean Medicine Rehabilitation
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• v.30 no.4
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• pp.89-103
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• 2020

Objectives This study has been conducted to verify frequently used herbs and herbal formulas to treat obesity in Korea during 2015 to 2019. Methods Publications related to treatment of obesity using herbal medicines from 2015 to 2019 were retrieved from 12 databases (PubMed, EMBASE, Scopus, China National Knowledge Infrastructure [CNKI], Koreanstudies Information Service System [KISS], National Digital Science Library [NDSL], Research Information Sharing Service [RISS], DBPIA, KMBASE, KoreaMed, KoreanTK, Oriental Medicine Advanced Searching Integrated System [OASIS]). Extracted articles were analyzed in terms of publication year, journal, and type of herbs. Results A total of 136 studies have been included in this study. 33 herbal formulaes and 129 herbs have been analyzed. Taeyeumjowui-tang was the most frequently studied herbal formulae and Ephedrae Herba was the most frequently studied herb. Ginseng Radix was the most frequently studied single herb in isolation from herbal formulae. Conclusions These results suggest that various herbs and herbal formulae can be used to treat obesity. Since this study includes every type of study, additional studies based on clinic are thought to be necessary.

• Journal of Sasang Constitutional Medicine
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• v.13 no.1
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• pp.109-118
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• 2001

1. The purpose of this study This study was performed on the basis of clinical consideration about rhinitis patients who suffered from sneeze, rhinorrhea, rhinocleisis and etc. And we checked the clinical inclination of this disease and the characteristic treatments of Sasang Constitutional Medicine. 2. The method of this study For 17 months from October in 1999 to April in 2001 we selected outpatients who had consulted for rhinitis more than twice in the department of the Sasang Constitution of the Bundang Oriental medical hospital, Dongguk University, and 31 of those were confirmed of their course of treatment. From their medical records and history, we learned the general characterisics and patterns of rhinitis, and the qualities and effects of its various treatment. 3. The result of this study The result were as follows ; 1) The rate of patients who have had the symptoms over the two years was 74.2%. 2) In the distribution of chief symptoms, sneeze occupied 80.6% of all appealed symptoms, rhinocleisis 77.4%, rhinorrhea 71.0%, intranasal pruritus 54.8%, postnasal drip 16.1%, orderly. 3) The treatment period was about 30days. The method of treatment was the Herb-med Tx, acupuncture Tx and etc. The herb-med ingestion was about two times in that period. 4) On the effect of treatment, Sneeze and rhinocleisis were improved. 5) The symptoms of rhinitis was more depravated by fatigue and stressful condition than weather condition. This result shows that the improvement of general condition has an effect on the rhinitis treatment.

• The Journal of Pediatrics of Korean Medicine
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• v.15 no.2
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• pp.43-51
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• 2001

Background : In recent years, obese patient have increased, but there were a few clinical report of herb &acupunture of the obesity. Objective : The aim of this study was to report the effect of Kamijowisengchungtang &Acupunture in 66 cases of obese patient. Material and Method : The clinical study were done on 66 cases of obese patients who were treated by Kamijowisengchungtang &Acupunture in Dept. of Oriental Medicine Kunsan Medical Center from February 2000 to May 2000 Result : After treatment, the weight was reducted statistically from $70.14{\pm}10.69kg\;to\;66.26{\pm}10.37kg$. Conclusion : We know that Kamijowisengchungtang &Acupunture Therapy is effective treatment in obese patient.

• The Journal of Pediatrics of Korean Medicine
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• v.25 no.3
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• pp.1-11
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• 2011

Objectives: The purpose of this study is to investigate various treatments in other countries for nocturnal enuresis. We analyze the treatments on enuresis (within acupuncture, moxibustion, psychotherapy and chiropractic) and herb for 12 years (from 2000 to 2011). Methods: Databases include PubMed and Web of Science. To narrow the search, the following key search terms were used: 'enuresis, acupuncture', 'enuresis, moxibustion', 'enuresis, psychotherapy', 'enuresis, chiropractic' and 'enuresis, herb'. The search was limited to the publication date from 2000 to 2011. Results: There are 31 studies on enuresis treatment by using acupuncture, 3 on moxibustion, 91 on psychotherapy, and 8 on chiropractic. Among them, 27 studies on acupuncture, 3 on moxibustion, 86 on psychotherapy and 5 on chiropractic reveal that patients with enuresis benefit from the each treatment. Conclusions: In the future, various researches on acupoint are necessary. Especially, studies on enuresis by using psychotherapy and chiropractic are needed. With those efforts, treatments on enuresis will become more pragmatic and beneficial.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.26 no.1
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• pp.97-103
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• 2013

Objective : To observe effects of TKM (Traditional Korean Medicine) treatment for psoriasis vulgaris. Methods : We did retrospective chart review for 32 psoriasis vulgaris patients who had been treated by TKM. TKM treatment included acupuncture, herb med, external herbal solution and moxibustion. Result : PASI (Psoriasis Area and Severity Index) 75 responding rate at treatment week 16 was 71.9%. Mild symptom patients' improvement rate and moderate to severe symptom patients' improvement rate was similar. Mean PASI score was increased until treatment week 4 to 8, and after that period, mean PASI score was decreased. Conclusion : This study suggest that TKM may be an effective treatment for psoriasis vulgaris.

• CELLMED
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• v.2 no.2
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• pp.18.1-18.16
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• 2012

An oncology-specific database called OncoRx (http://bit.ly/cancerRx) was previously set up in cyberspace to aid clinicians in identifying interactions of anticancer drugs (ACDs) and chemotherapy regimens with traditional Chinese medicines (TCMs) and complementary and alternative medicines (CAMs). Since then, users have requested the drug-CAM interactions (DCIs) of 5 specific CAMs (cranberry, melatonin, co-enzyme Q10, huachansu, reishi mushroom) to be updated in the database. Pharmacokinetic properties (metabolism, enzyme induction/inhibition, elimination), TCM properties and DCIs of each CAM were collated with 117 ACDs using 9 hardcopy compendia and online databases as resources. Additionally, individual ACDs and CAMs were used as keywords for PubMed searches in combination with the terms 'anticancer drugs', 'drug interactions', 'herb-drug/drug-herb interactions', 'pharmacokinetic interactions' and 'pharmacodynamic interactions'. DCI parameters consisted of interaction effects, evidence summaries, proposed management plans and alternative non-interacting CAMs, together with relevant citations and update dates of the DCIs. OncoRx is also used as a case to introduce the "Four Pharmaco-cybernetic Maxims" of quality, quantity, relationship and manner to developers of digital healthcare tools. Its role in Hayne's "5S" hierarchy of research evidence is also presented. OncoRx is meant to complement existing DCI resources for clinicians and alternative medicine practitioners as an additional drug information resource that provides evidence-based DCI information for ACD-CAM interactions.