• Title/Summary/Keyword: Heo hun

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A Case of Tarsal Bone Tuberculosis in a Patient with Polycythemia Vera (진성 적혈구 증다증 환자에서 발생한 발목뼈 결핵 1 예)

  • Kob, Sung-Ae;Jeong, Seon-Yeong;Shon, Se-Hun;Kim, Dong-Gun;Park, Sung-Woo;Heo, Ji-An;Lee, Kyung-Hee;Kim, Min-Kyoung;Hyun, Myung-Soo
    • Journal of Yeungnam Medical Science
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    • v.26 no.1
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    • pp.44-48
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    • 2009
  • Talus tuberculosis is a rare disease, even in an endemic tuberculosis area. In reviews of the worldwide literature, only 18 cases of talus tuberculosis have been reported. Recently, we experienced a case of a 70-year-old polycythemia vera patient with right metatarsopharyngeal joint pain for 2 months duration who was diagnosed with talus tuberculosis with prostate involvement. Tuberculosis should be considered as one of the causes of monoarticulitis, especially in countries, where the disease is endemic. Additionally, we highly recommend taking a biopsy of the site of suspected infection because an early diagnosis is the key to successful treatment.

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Effects of the Chestnut Inner Shell Extract on the Expression of Adhesion Molecules, Fibronectin and Vitronectin, of Skin Fibroblasts in Culture

  • Chi, Yeon-Sook;Heo, Moon-Young;Chung, Ji-Hun;Jo, Byoung-Kee;Kim, Hyun-Pyo
    • Archives of Pharmacal Research
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    • v.25 no.4
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    • pp.469-474
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    • 2002
  • The inner shell of the chestnut (Castanea crenata S. et Z., Fagaceae) has been used as an anti-wrinkle/skin firming agent in East Asia, and preliminary experiments have found that a 70% ethanol extract from this plant material can prevent cell detachment of skin fibroblasts from culture plates. In order to examine the molecular mechanisms underlying this phenomenon, its effects on the expression of adhesion molecules, such as fibronectin and vitronectin, were investigated using the mouse skin fibroblast cell line, NIH/3T3. Using fixed-cell ELISA, Western blotting and immunofluorescence cell staining, it was clearly demonstrated that the chestnut inner shell extract enhanced the expression of the cell-associated fibronectin and vitronectin. Scoparone (6,7-dimethoxycoumarin), isolated from the extract, also possessed similar properties. These findings suggest that the enhanced expression of the adhesion molecules may be one of the molecular mechanisms for how the chestnut inner shell extract preventing cell detachment and may be also responsible for its anti-wrinkle/skin firming effect.

Recent increase of human granulocytic anaplasmosis and co-infection with scrub typhus or korean hemorrhagic fever with renal syndrome in Korea

  • Heo, Dae-Hyuk;Hwang, Joo-Hee;Choi, Seung Hee;Jeon, Mir;Lee, Ju-Hyung;Lee, Jae-Hoon;Hwang, Seon-Do;Lee, Kyeong-Ah;Lee, Seung-Hun;Lee, Chang-Seop
    • Journal of Korean Medical Science
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    • v.34 no.11
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    • pp.87.1-87.6
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    • 2019
  • We report 17 patients with human granulocytic anaplasmosis between January 2015 and September 2018 at two tertiary university hospitals in Korea. Monthly incidence peaked in May and June. Among these patients, we identified three who were co-infected with scrub typhus, and one patient with hemorrhagic fever with renal syndrome.

Ground Firing Test Facility of Hybrid Rocket Engine (하이브리드로켓엔진 지상연소시험 설비)

  • Kim, Soo-Jong;Kim, Gi-Hun;Cho, Jung-Tae;Cho, Min-Kyoung;Do, Gyu-Sung;So, Jung-Soo;Heo, Jun-Young;Lee, Jung-Pyo;Park, Su-Hayng;Moon, Hee-Jang;Sung, Hong-Gye;Kim, Jin-Kon
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2008.11a
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    • pp.251-254
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    • 2008
  • Ground firing test facility and test field for firing test of hybrid rocket engine were constructed. Ground firing test facility were composed of hybrid rocket engine, thrust stand, oxidizer storage/supply system, control system and data acquisition system. Firing tests of thrust 50 kgf class were conducted. Stable performance data was obtained and operational reliability of ground firing test facility were found.

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Noise Reduction Algorithm For The Detection of Fine Ion Signals in Residual Gas Analyzer (잔류가스분석기의 질량 스펙트럼 검출 성능 향상을 위한 잡음제거 알고리즘)

  • Heo, Gyeongyong;Choi, Hun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.68 no.1
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    • pp.102-107
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    • 2019
  • This paper proposes a method to improve the mass spectral detection performance of the residual gas analyzer. By improving the mode estimation method for setting the threshold value and improving the additive noise elimination method, it is possible to detect mass spectrums having low peak values of the threshold level difficult to distinguish from noise. Ion signal blocks for each mass index with noise removed by the improved method are effective for eliminating invalid ion signals based on the linear and quadratic fittings. The mass spectrum can be obtained from the quadratic fitted curves for the reconstructed ion signal block using only the valid ion signals. In addition, the resolution of the mass spectrum can be improved by correcting the error caused by the shift of the spectral peak position. To verify the performance of the proposed method, computer simulations were performed using real ion signals obtained from the residual gas analysis system under development. The simulation results show that the proposed method is valid.

A Study on the Safety and Usability of University Dormitory Buildings (대학 기숙사 건물의 안전성 및 사용성 평가 연구)

  • Chae, Kyoung-Hun;Heo, Seok-Jae;Hur, Moo-Won
    • Journal of the Korean Institute of Educational Facilities
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    • v.26 no.2
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    • pp.3-10
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    • 2019
  • This study evaluated the vibration use and safety of students living in the dormitories on the 12th and 14th floors by feeling uncomfortable. The measurement method was to measure the acceleration due to free vibration and single - person walking. The slab stiffness was then calculated, and the usability and safety were compared according to international standards. The natural frequency of the slab was 6.8 Hz. The natural frequency of a typical slab is around 15Hz. Therefore, the evaluation slab is judged as a flexible floor structure. It is considered that there is a high possibility of resonance in the middle of daily life because of low natural frequency and near harmonic component of walking vibration. As a result, the RMS acceleration level is within the tolerance range defined by ISO 10137 code, but the 13th floor exceeds the reference limit, so that a sensitive person could detect the vibration somewhat in the lying position.

Pueraria montana var. lobata Root Extract Inhibits Photoaging on Skin through Nrf2 Pathway

  • Heo, Hee Sun;Han, Ga Eun;Won, Junho;Cho, Yeonoh;Woo, Hyeran;Lee, Jong Hun
    • Journal of Microbiology and Biotechnology
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    • v.29 no.4
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    • pp.518-526
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    • 2019
  • Pueraria montana var. lobata is a bioactive substance with various beneficial health effects and has long been extensively used as a traditional medication for the treatment of fever, acute dysentery, diabetes, and cardiovascular diseases in Northeast Asian countries. The purpose of this study was to evaluate the cytoprotective activity of Pueraria montana var. lobata ethanol extract (PLE) for ultraviolet B (UVB)-induced oxidative stress in human dermal fibroblasts (HDF). It was hypothesized that PLE treatment ($25-100{\mu}g/ml$) would reduce intracellular reactive oxygen species (ROS) levels as well as increase collagen production in UVB-irradiated HDF. The results confirmed this theory, with collagen production increasing in the PLE treatment group in a dose-dependent manner. In addition, regulators of cellular ROS accumulation, including HO-1 and NOQ-1, were activated by Nrf2, which was mediated by PLE. Hence, intracellular levels of ROS were also reduced in the PLE treatment group in a dose-dependent manner. In conclusion, PLE increases collagen production and maintains hyaluronic acid (HA) levels in human dermal fibroblasts exposed to UVB-irradiation, thereby inhibiting photoaging.

Research on BLDC motor control for CMT welding technique (자동차용 CMT 용접을 위한 BLDC 모터 제어 기술 연구)

  • Kang, Dong-Hun;Heo, Gyeong-Hyeon;Choi, Seung-Won;Lee, Jun-Young;Lee, Il-Oun;Park, Jun-Sung;Lee, Jae-Min;Byeon, Dong-Seop;Lee, Sang-Oh
    • Proceedings of the KIPE Conference
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    • 2019.07a
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    • pp.388-389
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    • 2019
  • 초박판 용접 기술인 CMT (Cold Metal Transfer) 용접을 위한 모터의 고정밀 정역동작 알고리즘 연구개발 결과를 본 논문에서 발표한다. CMT 용접 기술 구현을 위해 50W급 고정밀 속도 및 토크 제어가 가능한 맥슨모터의 EC-i40(BLDC 모터)을 사용하였고, DSP(TMS320F28069)와 모터 드라이버 IC(A3930)를 적용한 전용 제어 보드를 제작하여 CMT 동작 성능을 검증하였다. 실제 상용화되고 있는 용접전원장치(HF400R)와 본 논문에서 발표하는 CMT 기술을 연동하여 용접을 수행하면서 그 우수성을 확인하였다.

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Comparison of Efficiency According to the Two Control Method of the Wireless Charging System Considering Wired/Wireless Integrated Charging System for EV (전기자동차용 유·무선 통합 충전을 고려한 무선 충전 시스템의 두 가지 제어 방식에 따른 효율 비교·분석)

  • Heo, Hun;Lee, Ju-A;Sim, Dong-Hyun;Son, Won-Jin;Lee, Byoung-Kuk
    • The Transactions of the Korean Institute of Power Electronics
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    • v.27 no.3
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    • pp.228-236
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    • 2022
  • The charging methods of electric vehicles are divided into wired charging and wireless charging. Restrictions on the use of charging infrastructure for wireless charging vehicles currently exist because most charging infrastructure uses the wired charging method. Thus, wired and wireless integrated charging system has been studied. In this system, a wireless charging system especially requires a control method for high-efficiency operation in consideration of a change in a coupling coefficient. Therefore, this paper introduces two control methods for the high-efficiency operation of wireless charging that can be applied to wired and wireless integrated charging systems. In addition, loss analysis is performed through PSIM simulation to select a more advantageous method for high-efficiency operation among the two control methods. To verify the simulation-based loss analysis result, the two control methods are applied to the actual wireless charging system, and the efficiency is compared through the experiments Based on the experimental results, a control method suitable for high-efficiency operation of the wireless charging method is selected.

Suggestion for deep learning approach to solve the interference effect of ammonium ion on potassium ion-selective electrode

  • Kim, Min-Yeong;Heo, Jae-Yeong;Oh, Eun Hun;Lee, Joo-Yul;Lee, Kyu Hwan
    • Journal of the Korean institute of surface engineering
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    • v.55 no.3
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    • pp.156-163
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    • 2022
  • An ammonium ion with a size and charge similar to that of potassium can bind to valinomycin, which is used as an ion carrier for potassium, and cause a meaningful interference effect on the detection of potassium ions. Currently, there are few ion sensors that correct the interference effect of ammonium ions, and there are few studies that specifically suggest the mechanism of the interference effect. By fabricating a SPCE-based potassium ion-selective electrode, the electromotive force was measured in the concentration range of potassium in the nutrient solution, and the linear range was measured to be 10-5 to 10-2 M, and the detection limit was 10-5.19 M. And the interference phenomenon of the potassium sensor was investigated in the concentration range of ammonium ions present in the nutrient solution. Therefore, a data-based analysis strategy using deep learning was presented as a method to minimize the interference effect.