• Journal of Yeungnam Medical Science
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• v.3 no.1
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• pp.73-79
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• 1986

This study was conducted to evaluate the effects of lead on the incidence of anemia and to find cases with lead poisoning early among female workers who have been exposed to lead occupationally, for one year from August, 1985. The level of blood lead and hemoglobin concentration were observed for 284 female lead workers and 123 female non-lead workers of industries in the Gumi industrial complex in Kyungpook Province. The average age was $20.3{\pm}2.9$years and $21.1{\pm}3.5$ years in lead workers and non-lead workers, respectively. The average working duration was $26.46{\pm}19.26$ months in lead workers. The mean value of blood lead was $30.11{\pm}6.61{\mu}g/100ml$ and $21.86{\pm}3.75{\mu}g/100ml$ in lead workers and non-lead workers, respectively. There were significant differences between two groups. The mean value of hemoglobin concentration was $14.00{\pm}0.57g/100ml$ and $14.03{\pm}0.64g/100ml$ in lead workers and non-lead workers, respectively. Anemia cases were not observed at Hb concentration below 12g/100ml. The percentages of lead workers at Hb concentration ranged 12.0~13.0g/100ml were 4.5%. There was no dose-response relationship between blood lead level and the incidence of anemia. There were no remarkable differences between age and blood lead level as well as Hb concentration, and between working duration and the level of blood lead and hemoglobin.

• The Journal of Internal Korean Medicine
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• v.32 no.1
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• pp.1-9
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• 2011

Objectives : This study was performed in order to investigate the effect of Panax notoginseng(SCG) on phenylhydrazine (PHZ)-induced hemolytic anemia in rats. Materials and Methods : Rats were divided equally into 3 groups (Normal, Control, SCG). Anemic model rats (Control, SCG) were induced by the treatment of PHZ (40mg/kg/day, i.p.) for 3 days. Red blood cell, hemoglobin, reticulocyte count, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration were determined on days 0, 4, 7 and 10. Body weight was investigated on days 0, 2, 4, 6, 8, 10 and weight of spleen was measured on day 10. Results : In the SCG group, significantly higher levels of RBC was found on day 4 and higher concentration of Hb on days 4, 7 and 10. Furthermore, reticulocyte count was dramatically lower on day 10 compared to the control group. Conclusions : These results suggest that SCG may be beneficial in the treatment of hemolytic anemia.

• Korean Journal of Community Nutrition
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• v.2 no.3
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• pp.275-280
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• 1997

This study was conducted to assess the nutritional status of female students in the 6th grade in a rural primary school. The anthropometric data showed their mean height and weight were 149.5$\pm$6.5cm and 41.3$\pm$7.6kg, respectively, which are slightly higher than those in the Korean Standard Growth data. It was further observed that there was a wide variation in terms of physical growth and development among subjects. The mean hematocrit value was 40.3$\pm$3.3$\%$ and the mean hemoglobin concentration was 12.9$\pm$1.0gm/㎗. It was proven that 22.8$\%$ of subjects were anemic based on the WHO standards for hemoglobin level. Twenty four hour dietary recall revealed that their food intakes of subjects was appropriate, compared to the RDA except for Ca. Mean Ca intake among subjects was 381.3mg which is 47.7$\%$ of RDA. Nutrition education from mothers and the school influence nutrient intake significantly. Special nutrition education programs targeting mothers and students should be developed to provide practical assistance such as food choice and the forming of good eating habit.

• Korean Journal of Veterinary Research
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• v.46 no.4
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• pp.387-393
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• 2006

Progressing to the iron deficiency anemia was experimentally induced in 4 clinically healthy dogs by repeated phlebotomy to characterize hematologic features, serum iron values, and RBC indices. Abnormal RBC morphologies were also evaluated semiquantitatively on Wright's-stained blood films. Hematologic abnormalities in early stage of anemia included decreased both hematocrit and hemoglobin, and reticulocytosis, with no changes in mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) were represented. In intermediate stage, decreased serum iron concentration with microcytosis and hypochromia were prominent. In late stage, red cell distribution width and Mentzer's index were out of reference ranges in the majority of dogs. In this study microcytic anemia was appeared at the hemoglobin range of 5.1-7.2 g/dl. On most sampling days, platelet counts and white blood cells were within the reference ranges, with some minor variations. Iron deficiency was not necessarily associated with microcytic anemia. Judging from the sequential changes of both MCV and MCHC, 3 patterns of anemia were sequentially observed: initially normocytic normochromic, intermediate normocytic hypochromic or normocytic normochormic, and finally microcytic hypochromic. The most frequent morphologic abnormalities were target cells. Occasional elliptocyte, acanthocyte, stomatocyte, kinzocyte, dacrocyte and schistocyte were also noted on the blood films.

• Journal of Veterinary Clinics
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• v.19 no.1
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• pp.55-60
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• 2002

The Allium tuberosum is a perennial herb. From the ancient times, it has been used for food or medical purpose. Allium tuberosum is widely distributed in Korea, China, Japan and other countries. As herbal medicine, the Allium tuberosum has medical effects on lumbago, sthenia, diuresis, nocturia, hematemesis, anemia, haemorrhoid, hiccups, diarrhea, eczema, sunstroke, pollution and so on. Recently, the Allium tuberosum has been studied on its components, anti-microorganism action, anti-fungal action, anti-arteriosclerosis action, anti-cancer action. However, there has not been any study on hematological effect of allium tuberosum extract on the blood in large dogs whereas the effects of excess garlic and onion on the blood of cattle, horses, dogs, cats and sheep has been reported by many researchers. Thus, this study was performed to observe the hematological effect of excessive Allium tuberosum extract administrated in large dogs. 1. The Red Blood Cell(R3C) count was significantly decreased(p<0.05), Packed Cell Volume (PCV) count were significantly decreased(P<0.05), and Reticulocyte count was significantly increased(p<0.05) 2. The White Blood Cell(WBC) count was significantly increased(p<0.05).3. The Hemoglobin concentration was significantly decreased(p<0.05) and Mean Corpuscular Hemoglobin Concentration (MCHC) was increased. and Mean Corpuscular Volume(MCV) was significantly increased.(p<0.05). 4. The Reduced glutathione(GSH) and Met-Hemoglobin were significantly increased (p<0.05).

• Journal of Environmental Health Sciences
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• v.3 no.1
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• pp.45-47
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• 1976

A survey was carried out in order to figure out of phenomenon by school feeding from June 1973 to May 1974. Hematological values and plasma protein of 94 boys and 91 girls (total 185 students)were studied. As the results of this survey, the following conclusions were obtained. 1. Hemoglobin, hematocrit, mean corpuscular hemoglobin concentration of boys and girls were increased after school lunch. 2. Plasma protein of boys and girls were clearly increased after school lunch.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.5
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• pp.638-642
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• 2017

Objective: This study aimed to validate the statistical evidence from the genome-wide association study (GWAS) as true-positive and to better understand the effects of the glycophorin C (GYPC) gene on serum hemoglobin traits. Methods: Our initial GWAS revealed the presence of two single nucleotide polymorphisms (SNPs) (ASGA0069038 and ALGA0084612) for the hemoglobin concentration trait (HGB) in the 2.48 Mb region of SSC15. From this target region, GYPC was selected as a promising gene that associated with serum HGB traits in pigs. SNPs within the GYPC gene were detected by sequencing. Thereafter, we performed association analysis of the variant with the serum hemoglobin level in three pig populations. Results: We identified one SNP (g.29625094 T>C) in exon 3 of the GYPC gene. Statistical analysis showed a significant association of the SNP with the serum hemoglobin level on day 20 (p<0.05). By quantitative real-time polymerase chain reaction, the GYPC gene was expressed in eight different tissues. Conclusion: These results might improve our understanding of GYPC function and provide evidence for its association with serum hemoglobin traits in the pig. These results also indicate that the GYPC gene might serve as a useful marker in pig breeding programs.

• The Korean Journal of Food And Nutrition
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• v.25 no.4
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• pp.1047-1054
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• 2012

The purpose of this study was to compare the anthropometry, serum lipid levels, dietary behavior and health-related behaviors of shipbuilding workers. The education level was significantly higher in office workers than laborers, while age, monthly income and working years were not significantly different between both groups. The serum triglyceride, glucose concentration and AI were significantly higher in office workers than in laborers, but the serum LDL-cholesterol and HDL-cholesterol concentrations were significantly higher in laborers than in office workers. The frequency of breakfast and coffee intake was significantly higher in office workers than in laborers. In the office workers, age was positively correlated with systolic blood pressure but was negatively correlated with hemoglobin and hematocrit concentration In the laborers, working year was negatively correlated with hemoglobin, total cholesterol and serum LDL-cholesterol concentrations. Exercise was negatively correlated with total cholesterol concentration, triglyceride and LDL-cholesterol concentration and AI in the office workers. The results of this study showed that office workers are more prone to related chronic degenerative diseases. Therefore, nutritional education for the provention of chronic degenerative diseases of shipbuilding workers needs to be more focused on improving the health status of office workers.

• Korean Journal of Veterinary Research
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• v.45 no.1
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• pp.121-125
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• 2005

The present study was carried out to produce the hematological and blood chemical findings after hypophysectomy in rats. Hypophysectomy was performed by the parapharyngeal method and the sham surgery was performed for the control group. Two weeks after the operation, the body weight of the hypophysectomized and control rats was measured daily for 5 days. We deleted the rats the weight gain of which is less than 5 g during 5 days from the hypophysectomy group. The successful operation rate was approximately 40%. In the hypophysectomized and control rats, their blood samples were collected from posterior vena cava after celiotomy under generally anesthesia with ether. Hematological parameters such as erythrocyte count, leukocyte count, hemoglobin concentration, hematocrit level, and platelet count were determined by Animal Blood Counter. The erythrocyte count, hemoglobin concentration, and hematocrit level were lower significantly (p<0.01), and the leukocyte count was lower significantly (p<0.05) in hypophysectomy group compared with control group. But the plate count did not show significant difference (p>0.05) between hypophysectomy group and control group. Also, blood chemical parameters such as glucose, blood urea nitrogen (BUN), aspartate animotransferase, albumin, total protein, cholesterol, calcium, and magnesium in serum were determined. Except BUN concentration, all parameters were not affected by hypophysectomy. But the BUN concentration was higher significantly (p<0.01) in hypophysectomy group compared with control group.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.6
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• pp.828-836
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• 1996

The histological changes of gill, liver, spleen and muscle, and respiration and blood variables and liver glycogen content were examined in black seabream, Acanthopagrus schlegeli. Fish were exposed to a high level of total ammonia nitrogen (10.4 mg/l) and recovered from exposure $(0.4{\pm}0.2mg/l)$ in a closed recirculating seawater system. In the process of exposure, mortality was $9\%$, and hyperplasia, necrosis or inflammation appeared in all tissues except for muscle. Oxygen consumption was decreased by $49\%$, and red blood cell (RBC) number, hematocrit and hemoglobin concentration were significantly decreased, while plasma glucose contents, activities of glutamate-oxaloacetate transaminase (GOT) and glutamate-pyruvate transaminase (GPT) increased. Liver glycogen content significantly increased from $6.6\%\;to\;10.4\%$. A large amount of hemosiderin was observed in the splenic tissue. During the recovery period, RBC number, hematocrit, hemoglobin concentration, GOT and GPT activities were returned to the normal status. Histological status of liver tissue was returned to the normal, but liver glycogen content was not recovered. During the recovery period, spleen melanin-macrophages temporarily increased, but subsequently decreased to the normal status.