• 제어로봇시스템학회논문지
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• 제21권5호
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• pp.393-400
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• 2015

This paper describes the development of a chest-wearable robot that can efficiently perform self walking rehabilitation without a helper. The features of the developed robot are divided into three parts. First, as a mechanical characteristic, the conventional elbow crutch is attached at the forearm. However, the proposed robot is attached to the patient's chest, enabling them to feel free to use their hands and eliminate the burden of the arms. Second, as a characteristic of the driving algorithm, pressure sensors attached to the chest automatically perceive the patient's walking intention and move the robot-leg thereafter. Also, for safety, it stops operating when an obstacle is found in front of the patient by using ultrasonic sensors and generates a beeping sound. Finally, by using the scotch yoke mechanism, supporting legs are moved up and down using a rotary servo motor without excessive torque that is generated by large ground reaction forces. We showed that the developed robot can effectively perform self walking rehabilitation through walking experiments, and its performance was verified using Electromyograph (EMG) sensors.

• 대한화학회지
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• 제59권1호
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• pp.45-53
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• 2015

이 연구의 목적은 Nature-Study 관련 문헌 연구를 통해 Nature-Study의 교육방법을 도출하고 이 교육방법이 오늘날 과학교육에 주는 의의를 고찰하는 것이다. 이를 위하여 Nature-Study의 역사적 연구를 발전시켜 Nature-Study의 교육관점을 도출하고 19세기 후반에서 20세기 초반에 출판된 Nature-Study 관련 문헌을 수집 분석하여 각 교육관점에 따른 교육방법을 추출하였다. 또한 추출한 교육방법을 바탕으로 Nature-Study가 오늘날 과학교육에 주는 의의를 고찰하였다. 연구 결과 Nature-Study는 자연에 대한 학습이라는 관점에서 학생과 자연의 교감을 강조하고, 교과 통합적 학습을 중시하며, 비형식적 학습을 학교 수업에 포함시키는 교육방법을 지향한다. 또 직접 경험을 통한 학습이라는 관점에서 야외 활동을 지향하고, 교재보다 경험이 선행될 것을 강조하며, 기초적인 관찰을 중시한다. 마지막으로 학습자 중심의 학습이라는 관점에서 학생의 흥미를 중요시하고, 모든 학생을 위한 교육을 지향하며, 조력자로서 교사의 역할을 강조한다. 이와 같은 Nature-Study 사상은 오늘날 과학교육에 '자연을 통한 과학학습'으로의 관점 전환이 필요함을 시사한다.

• 대한인간공학회지
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• 제31권6호
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• pp.705-713
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• 2012

Objective: The aim of this study is to predict human visual target search using ACT-R cognitive architecture in real scene images. Background: Human uses both the method of bottom-up and top-down process at the same time using characteristics of image itself and knowledge about images. Modeling of human visual search also needs to include both processes. Method: In this study, visual target object search performance in real scene images was analyzed comparing experimental data and result of ACT-R model. 10 students participated in this experiment and the model was simulated ten times. This experiment was conducted in two conditions, indoor images and outdoor images. The ACT-R model considering the first saccade region through calculating the saliency map and spatial layout was established. Proposed model in this study used the guide of visual search and adopted visual search strategies according to the guide. Results: In the analysis results, no significant difference on performance time between model prediction and empirical data was found. Conclusion: The proposed ACT-R model is able to predict the human visual search process in real scene images using salience map and spatial layout. Application: This study is useful in conducting model-based evaluation in visual search, particularly in real images. Also, this study is able to adopt in diverse image processing program such as helper of the visually impaired.

• 융합정보논문지
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• 제10권5호
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• pp.111-116
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• 2020

최근 어린이 차량의 승하차 과정에서 어린이 안전사고가 발생한다. 차량 인솔 교사가 없는 경우 버스에서 하차하지 않은 어린이의 질식사나 차량 전후방의 사각지대의 어린이 안전사고가 빈번하게 발생한다. 딥러닝 기반의 얼굴인식기술을 스마트 미러에 적용하여 사용자인증의 활용시 안전사고 방지를 위한 서비스가 가능하다. 스마트미러는 어린이를 위한 도우미 역할이 가능하고, 운전기사나 선생님이 미처 발견하지 못해 발생 가능할 사고를 방지할 수 있다. 어린이의 얼굴을 사전에 등록하여 어린이의 승하차시에 사용자인증을 수행하여 누락되지 않고, 버스의 전후방에 근접센서 및 카메라를 통해 안전사고를 미연에 방지할 수 있다. 본 연구는 어린이의 버스 승하차 과정에서 누락여부를 확인하고, 차량 전후방의 사각지대를 줄일 수 있는 시스템을 설계하고, GPS 정보를 활용하여 다양한 서비스가 가능한 안전시스템을 제안한다.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.61-77
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• 2016

목적: 본 연구에서는 TJ 열수추출물이 아토피 피부염에 미치는 효과를 확인하고자 하였다. 방법: 2, 4-dinitrochlorobenzen (DNCB)으로 BALB/c 마우스에 1차 감작 후 3주간 2차 감작을 시행하여 아토피 유사 피부병변을 나타내는 접촉성 피부염을 유발한 뒤 동결건조 처리된 TJ 분말을 (PBS/EtOH/Cremophor=6:1:3)에 용해시켜 쥐의 등 피부에 10, 50 mg/ml 농도로 3주간 도포하였다. 결과: TJ 열수추출물은 아토피 피부 병변의 염증세포 침윤을 억제하였고 (10, 50 mg/ml ) 표피와 진피 두께를 회복시켰으며 (10, 50 mg/ml ), 혈청에서 히스타민 방출을 억제하였다 (00 mg/ml ). 또한 Th2 세포와 관련된 cytokine인 interleukin (IL)-4, IL-5, IL-13과 thymic stromal lymphopoietin (TSLP)의 mRNA 발현 양을 감소시켰고 (10, 50 mg/ml ), Th2 chemokine인 thymus- and activation-regulated chemokine (TARC or CCL17)의 mRNA의 발현 양을 감소시켰다 (10, 50 mg/ml ). 결론: TJ 열수추출물을 BALB/c 마우스에 외용하였을 때 항아토피 효과가 있음을 확인하였으며 따라서 TJ가 아토피 피부염 치료의 외용제로 활용될 수 있을 것으로 사료된다.

• 동의신경정신과학회지
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• 제15권2호
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• pp.89-101
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• 2004

Objective : The present experiments were designed to study on the immune-enhancing effect of Mountain grown ginseng, Mountain cultivated ginseng, and Panax ginseng Method : In order to compare the immune-enhancing effect of moutain grown ginseng, moutain cultivated ginseng and Panax ginseng, the study was done through the forced swimming test (FST), measurement of T helper Th1, Th2 cytokines and fatigue related factors. Result : Moutain grown ginseng and panax ginseng decreased the immobility time in the FST compared to the control. Glucose, blood urea nitrogen (BUN), creatinine, lactate dehydrogenase (LDH) and Total-protein (T-protein) in serum were investigated. The serum achieved from ginseng administered mouse showed higher BUN, T-protein than the control. moutain grown ginseng administered group showed lower LDH than the control group. moutain grown ginseng administered mouse showed higher glucose than the control. Creatinine was same in either experimental or control group. Ginseng-induced cytokine production in human T-cell line, MOLT-4 cells and mouse peritoneal macrophages were compared. Moutain cultivated ginseng (10-4 dilution) and panax ginseng (10-3 dilution) were increased the interferon $IFN-{\gamma}$ production compared with media control (about 1.6-fold P<0.05) at 48 h. Moutain grown ginseng (10-4 dilution) was increased the $IFN-{\gamma}$ and interleukin IL-4 production compared with media control (about l.4-fold for $IFN-{\gamma}$ and 1.6-fold for IL-4 P<0.05) at 48 h. Moutain grown ginseng (10-3 dilution) and moutain cultivated ginseng (10-4 dilution) were increased the turmor necrosis factor $TNF-{\alpha}$ production compared with $rIFN-{\gamma}$ treated cells (about 1.9-fold for $TNF-{\alpha}$ P<0.05), respectively. Moutain cultivated ginseng (10-3 dilution) was increased the IL-12 production compared with $rIFN-{\gamma}$ treated cell (about 1.7-fold for IL-12 P<0.05). Conclusion : These data suggest that three different three kinds of ginseng act on immune responses in different aspects.

• 대한바이러스학회지
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• 제27권2호
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• pp.209-216
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• 1997

Three dimensional structures of envelope protein from Korean isolates and Nakayama-NIH strain of Japanese encephalitis virus (JEV) were deduced by a computer program (HyperChem 4.0 Chemplus 1.0) based on the data of the three dimentional structure of Tick-borne encephalitis virus. In the three dimensional structure of envelope protein, neutralizing epitope and T-helper cell recognition site of C-terminal region of Korean isolates were structually similar to those of Nakayama-NIH but the N-terminal region was not. Korean JE isolates were compared with Nakayama-NIH strain by using cross-neutralization antibody test. Neutralizing activities of Korean isolates derived from guinea pigs were higher than those of Nakayama-NIH strain against Korean isolates, although the polyclonal antibody titers of Nakayama-NlH showed 1:160 to 1:640 against Korean isolates. According to the results from three dimentional structures and cross-neutralization analyses, the antigenic difference between Korean JE isolates and Nakayama-NIH strain may be dependent on structural difference of envelope protein.

• 한국축산식품학회지
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• 제31권3호
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• pp.420-427
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• 2011

The use of lactic-acid bacteria (LAB) is effective for preventing and curing immune disorders by activating the immune system in the digestive tract and the consequent immune response in the blood. In this study, LAB and mixed LABs were used in an atopic dermatitis (AD) mouse model. Alleviation of AD was observed based on the change in cytokine level and immunohistochemical staining. An ex vivo test showed that immunoglobulin-E and interleukin (IL)-4 levels were significantly lower in all groups treated with LAB than in the group treated with only 1-chloro-2,4-dinitrobenzene. Results of an in vivo test based on the ex vivo results showed that the scratch score decreased in all groups treated with the LAB and particularly decreased in the group treated with mixed LABs. Additionally, the T helper (Th) 1 cytokines interferon-gamma and IL-12p40 were upregulated by the LAB and mixed-LABs, whereas levels of the Th2 cytokine IL-4 were downregulated in a mouse model of AD-like skin lesions. Furthermore, hematoxylin & eosin and immunohistochemical staining of the dorsal area of the mice in each group showed that AD improved in the LAB-treated groups. These results suggest that LAB and mixed LABs inhibit the development of AD in NC/Nga mice by suppressing the Th2 cell response and increasing the Th1 cell response. Our results indicate that mixed LABs are better than LAB for treating AD-like skin lesions.

• 한국콘텐츠학회논문지
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• 제7권12호
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• pp.83-94
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• 2007

포트폴리오는 구성주의 학습을 지원하는 한 방법으로 사용될 수 있다. 현재 교육 현장에서 포트폴리오의 사용이 점차 확대되고 있으나, 현장 적용의 실태나 발전적 활용 방안에 대한 연구는 미약한 편이다. 본 논문에서는 전국의 초 중등학교 재직 교사를 대상으로 포트폴리오 운영에 대한 실증적 자료를 분석하며, 이를 기반으로 지식정보화 사회에 필요한 e-포트폴리오의 설계 방향을 제안한다. 포트폴리오에 대한 이해도, 유형별 운영 현황 분석 결과에 따르면 학교급에 따른 차별화된 시스템 설계와 고경력자에 대한 연수 확대, '안내도우미' 기능 구비를 필요로 한다. 포트폴리오 작성을 위해 많은 시간을 소요하고 일회적, 형식적 수행 평가의 일환으로 운영되는 문제점을 개선하기 위해 학습과 평가를 하나의 과정에서 통합하는 시스템의 설계가 필요하다. 더불어 상호작용 및 자기 주도적 학습을 효과적으로 지원하는 e-포트폴리오의 설계가 요구된다.

• 유통과학연구
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• 제17권5호
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• pp.103-111
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• 2019

Purpose - This paper aims to examine a spirituality's impact on the posttraumatic interpersonal relationships of family violence with a structural equation model(SEM). This article starts with the research idea that family violence experience bring about negative emotion in terms of interpersonal relationship leading to the distribution of negative affect in social relationship. The research question of this study pinpoints on how family violence experience affects interpersonal relationship problems and how spirituality affects interpersonal relations problems. Based on the idea, we attempts to deal with spirituality's impact as a driving factor of transforming the distribution of negative affect. Research design, data, and methodology - The structural equation modelling(SEM) is employed as a analysis method of this study. SEM provides a chiefly cross-sectional statistical modelling method, and moreover it allows multiple variables to be associated with a latent variable in this analysis. 300 samples from Seoul, Gyeonggy and Gangwon are selected in the survey. We chose available 271 among them. Results - The results verify that trauma have placed an negative impact on personal relations. The study results also shows that the more serious get the degree of family violence trauma, the worse become interpersonal relationship problems. What is more interesting is that the degree of trauma's impact on interpersonal relation problems in male is higher than that of trauma's impact in female. It is mainly attributed to the fact that women are superior to men in terms of empathy ability and interpersonal relationship orientation. It can be noted that the well-managed spirituality will be able to make a great contribution towards reducing the degree of trauma caused by interpersonal relationships. Conclusions - The study results demonstrates that family violence have negative impacts on spirituality, while spirituality have an positive impacts on reduction the problems of interpersonal relationship. It has been found out that family violence trauma may cause negative affectivity in personal relations, which can distribute negative impacts regarding interpersonal relationship in society. This study also supports that spirituality will be able to function well as a helper, which may reduce the distribution of negative affect in society.