• Physical Therapy Rehabilitation Science
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• v.7 no.3
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• pp.95-101
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• 2018

Objective: To determine if the provision of visual biofeedback using real-time rehabilitative ultrasound imaging (RUSI) enhances the acquisition and retention of diaphragm muscle recruitment during exercise. Design: Two group pretest posttest design. Methods: Thirty healthy subjects were randomly assigned to the verbal feedback group (VG, n=15) or the visual and verbal feedback group (VVG, n=15). The VG performed breathing exercises 10 times with verbal feedback, and the VVG also performed breathing exercises 10 times with verbal feedback and visual feedback with the use of RUSI to measure changes in diaphragm thickness (DT). For DT, the mid-axillary lines between ribs 8 and 9 on both sides were measured in standing, and then the chest wall was perpendicularly illuminated using a linear transducer with the patients in supine to observe the region between rib 8 and 9 and to obtain 2-dimensional images. DT was measured as the distance between the two parallel lines that appeared bright in the middle of the pleura and the peritoneum. After one week, three repetitions (follow-up session) were performed to confirm retention effects. Intra- and between- group percent changes in diaphragm muscle thickness were assessed. Results: In the VVG, the intervention value had a medium effect size compared to the baseline value, but the follow-up value decreased to a small effect size. In the between-group comparisons, during the intervention session, the VVG showed no significant effect on percent change of DT but had a medium effect size compared to the VG (p=0.050, Cohen's d=0.764). During the follow-up session, retention effect did not persist (p=0.311, Cohen's d=0.381). Conclusions: RUSI can be used to provide visual biofeedback and improve performance and retention in the ability to activate the diaphragm muscle in healthy subjects. Future research needs to establish a protocol for respiratory intervention to maintain the effect of diaphragmatic breathing training using RUSI with visual feedback.

• Journal of Nutrition and Health
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• v.31 no.8
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• pp.1315-1323
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• 1998

Effect of oral taurine supplementation on plasma total and phospholidpid -fatty acid profiles and their metabolism were evaluated in healthy female adults. Among twenty five female volunteers(23.6$\pm$0.3 years old ) participated in the taruine supplementation program(6g taurine /day), twenty four subjects succesfully completed the 2 week program , and only nine subjects continued to take taurine for another 2 weeks. Levels of plasma fatty acids and taruine were measured by gas-liquid chromatobraphy and an automated amino acid analyzer based on ion exchange chromatography, respectively. Plasma taurine concentration s of the subjects were 108. 7$\pm$3.4 , 184.2$\pm$8.2 and 235.9$\pm$77.0$\mu$emol/L at 0 , 2 and 4 weeks of taurine supplementation. Fatty acid compositions and elongation and desaturation indices of polyunsaturated fatty acids (PUFA) in plasma total lipids were not influenced by oral taurine supplementation. However, fatty acid compositions and their metabolism in plasma phospholipids were significantly affected by taurine supplementation in female adults. Compared to the values for 0 week, the percentage of saturated fatty acids (SFA) in plasma phospholipid was significantly lowered at 2 weeks, but elevated at 4 weeks of taurine supplementation. In contrast , the percentage of phospholipid PUFA significantly increased at 2 weeks and decreased at 4 weeks of taurine supplementation from to the values for 0 weeks. Foru weeks of oral taurine supplementation signifinatly elevated the eongation index(20 : 4$\omega$6 ⇒22 : 4 $\omega$6, p<0.01), and decreased the desaturation index (20 : 3 $\omega$6 ⇒20 : 4 $\omega$6 , p<0.01) of $\omega$6 fatty acids in plasma phospholipids. Plasma taurine concentration was positively correlated with the percentage of 14 : 0 fatty acids and the enlongation index o f$\omega$3 fatty acids(20 : 5 $\omega$3 ⇒22 : 5 $\omega$3), and thenegatively correlated with the percentage of 20 : 0 in plasma phospholipids. These results indicate that oral taurine supplementation for 4 weeks signidicantly elelvated the percentage of SFA, and lowered the percentage of PUFA in plasma phospholipids with no influence on plasm total fatty aicd composition in healthy female adults.

• The Journal of Korean Medicine
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• v.28 no.3 s.71
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• pp.138-143
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• 2007

Objective : This study aimed to investigate differential cancer incidence among Sasangin comparing to healthy subjects in the Republic of Korea. Methods : The medical records of 169 patients who had taken diagnosis of Sasang constitution from October 2004 to January 2007 at the East-West Cancer Center in Dunsan Oriental Hospital of Daejeon University were reviewed. Diagnosis was done by Questionnaire for Sasang Constitution ClassificationII (QSCCII). Results : Among the 169 patients, 37.9%, 22.5% and 39.6% belonged to Soyangin, Taeumin and Soeumin, respectively. This is significantly different from the distribution rate of Sasang in amonghealthy subjects (29.1%, 46.9% and 24.0% respectively to Soyangin, Taeumin and Soeumin). This pattern appeared in a similar way among individual cancer analysis: breast cancer (37.5%, 21.9%, 40.6%), colon cancer (41.7%, 20.8% 37.5%), and HCC (35.0%, 20.0%, 45.0%). Stomach cancer typically showed remarkable incidence in Soeumin as high as 50.0% and lung cancer showed in Soyangin as high 46.7%, but it didn't have statistical significance. The mean age of 50.9 years was higher than for healthy people (46.3). Conclusion : Sasang distribution of cancer patients is different from that of healthy subjects. Further study is needed on individual cancers.

• Progress in Superconductivity
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• v.9 no.1
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• pp.29-34
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• 2007

The baseline selection is the first and important step to analyze magnetocardiography (MCG) parameters. There are no difficulties to select the baseline between P- and Q-wave peak (P-Q interval) of MCG wave recorded from healthy subjects because the P-Q intervals of the healthy subjects do not much vary. However, patients with ischemic heart disease often show an unstable P-Q interval which does not seem to be appropriate for the baseline. In this case, T-P interval is alternatively recommended for the baseline. However, there has been no study on the difference made by the baseline selection. In this study, we studied the effect of the different baseline selection. MCG data were analyzed from twenty healthy subjects and twenty one patients whose baselines were alternatively selected in the T-P interval for their inappropriate P-Q interval. Paired T-test was used to compare two set of data. Fifteen parameters derived from the R-wave peak, the T-wave peak, and the period, $T_{max/3}{\sim}T_{max}$ were compared for the different baseline selection. As a result, most parameters did not show significant differences (p>0.05) except few parameters. Therefore, there will be no significant differences if anyone of two intervals were selected for the MCG baseline. However, for the consistent analysis, P-Q interval is strongly recommended for the baseline correction.

• Journal of the Korean Society of Physical Medicine
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• v.12 no.1
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• pp.15-24
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• 2017

PURPOSE: The purpose of this study was to investigate the effects of supplementary verbal encouragement according to the gender on the activation of abdominal muscles during performance of crunch exercise in healthy subjects. METHODS: A Total of 32 healthy subjects (15 male and 17 female) were randomly allocated to two conditions, crunch exercise with Ki-hap and verbal encouragement with same gender (CKVS) and crunch exercise with Ki-hap and verbal encouragement with different gender (CKVD). The interventions were conducted over three trials in each condition, and measurements were performed on each subject by one examiner in three trials. The activation of rectus abdominis, external oblique, internal oblique, and transverse abdominis muscles were evaluated using electromyography (EMG) during performance of crunch exercise with Ki-hap and verbal encouragement with same gender or different gender, respectively. RESULTS: The results showed that there were no significantly difference in the activation of all abdominal muscles in those of the CKVS compared with the CKVD (p>.05). The results also showed that there were no significantly difference in the ratio of muscle activation at global muscle to that at local muscle between two conditions (p>.05). CONCLUSION: These findings demonstrated that application of the supplementary verbal encouragement by gender does not affect to activate the abdominal muscles of subject to perform a movement, at the same time, it would suggest positive evidence for improving activation of abdominal muscles.

• Journal of Oriental Neuropsychiatry
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• v.20 no.4
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• pp.127-135
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• 2009

Objectives : This study was conducted to assess the effect of Chunwangbosim-dan(CB) on the autonomic nervous system by using heart rate variability measurement. Methods : The eligible subjects were composed of the healthy female group of ages 25 to 30 years. They were divided into two groups, the CB group(n=16) and the control group(n=16). We measured the heart rate variability respectively for 3 times at 14:00, 16:00, and 17:00. In the CB group, subjects were administered CB at 15:00. For the measurement values, Mean Heart Rate and SDNN(standard deviation of the NN intervals) were used as time domain analysis, and HF(high frequency), LF(low frequency), and LF / HF ratio were used as frequency domain analysis. Results : The degree of LF changes in the CB group was significantly lower than control group at 1 hour after administration. Conclusions : We suggest that Chunwangbosim-dan may be useful for stabilization of the autonomic nervous system by controlling sympathetic nerve in healthy people.

• The Journal of Korean Medicine
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• v.38 no.4
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• pp.41-54
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• 2017

Objectives: The purpose of this study is to investigate the effects of Sa-am acupuncture with Pericardium jung-gyuck (SA-acu-PC) and Triple Energizer jung-gyuck (SA-acu-TE) on the radial pulse in healthy human subjects. Methods: Sixty healthy subjects participated in this study and divided into three groups randomly: Control group(C), Pericardium jung-gyuck group(PC), Triple Energizer jung-gyuck group(TE). Radial pulse was measured by 3 dimensional pulse imaging system (DMP-3000) before, right after, 30 minutes after, and 60 minutes after acupuncture. Results: 1. The changes observed in periodic parameters are considered as the common effects of both SA-acu-TE and SA-acu-PC. SA-acu-TE was more effective than SA-acu-PC in these effects. 2. The effects of SA-acu-PC appeared in the pulse amplitude, pulse area, and pulse power volume mainly at the left chon position, and 3. The effects of SA-acu-TE appeared in the radial augmentation index and main peak angle mainly at the right gwan position. Conclusions: The effects of SA-acu-PC and SA-acu-TE can be observed in the radial pulse. The increases in pulse amplitude, pulse area, and pulse power volume at the left chon may imply the effects of SA-acu-PC. And the decrease in the pulse power volume, the increases in radial augmentation index and main peak angle may imply the effects of SA-acu-TE.

• Journal of Nutrition and Health
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• v.33 no.3
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• pp.332-342
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• 2000

Vitamin mineral supplement usage by self-prescription is popular behavior among adolescents. This study was conducted to investigate the behaviors of vitamin·mineral supplement usage and the relationship between demographic variables and supplement usage by healthy adolescents. Nine hundred seventy two boys and girls, aged 13-18 years, attending general middle or high schools were chosen from various cities and rural communities in Korea. As a result, vitamin·]mineral supplements were taken by 31.3% of subjects. Users tended to take vitamin·mineral supplements more frequently when they were healthy than when they suffered from disease. The taking period of supplements was different according to school type such as middle or high school(p<.05), sex(p<.001) and residence of subjects(p<.01). The main information source of supplements was newspaper/magazine/TV, and it was affected by sex(p<.05) and residence(p<.01). Vitamin·mineral supplements were generally recommended by their mothers instead of health professionals. The commonly cited taking reason of supplements was affected by sex(p<.01)and socioeconomic status of family(p<.05). The frequently responded effect obtained from supplement use was recovery from fatigue and it was different according to sex(p<.01). The major mentioned reason of not taking vitamin·mineral supplements by non-users was 'I eat a balanced diet'. The most frequently consumed supplements were vitamin C, followed by multi-vitamins supplements, and this pattern was different according to school type(p<.001), sex(p<.01) and residence(p<.05). These findings show that the behaviors of vitamin·mineral supplement usage by subjects are not resonable, and their supplement usage tends to be affected by demographic variables. Therefore, nutritional understanding and education that are intended to form the resonable behaviors toward vitamin·mineral supplement usage of adolescents should be provided with considering the relationship between demographic variables and supplement usage.

• Nutritional Sciences
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• v.8 no.3
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• pp.189-195
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• 2005

To assess the effect of pinitol supplementation and strength training for two weeks on the anaerobic capacity during and after exercise, and improvement of glucose metabolism during the recovery period of muscular fatigue with repeated acute bouts of cycling exercise, a total of 24 healthy young men were recruited and randomly and equally divided into three groups; pinitol supplementation group (PSG), placebo group (PLG), and control group (CON). Using a randomized double-blinded design, subjects in PSG were provided pinitol supplement, consumed orally 1.2 g/day, and participated in the resistance exercise program and cycling exercise for two weeks. Subjects in PLG underwent the same protocol as those in PSG but consumed the same amount of placebo. No supplementation and exercise program was given to CON. Before and after the intervention, all subjects were tested for their anaerobic capacities evaluated by Wingate test twice separated by 30 min. During the test, peak anaerobic power (PP), mean anaerobic power, total work, and fatigue index were evaluated During resting and recovery, blood samples were drawn and plasma pinitol, myo-inositol, chiro-inositol, insulin, free fatty acid, glucose, and lactate levels were analyzed After two weeks, PP and relative PP of the second biking were improved from the first biking in PSG only (p<0.05). No changes were found in all other variables of Wingate test in all groups. No statistical differences between groups and pre- and post-intervention were observed in concentrations of pinitol, myo-inositol, and chiro-inositol, but pinitol concentration was higher during recovery compared to the baseline in all groups and testings (p<0.05). Lactate level during recovery was higher than the resting level, but no other blood parameters were significantly changed. In conclusion, two weeks of pinitol supplementation in conjunction with short duration of anaerobic training in healthy young men did not induce any obvious benefits in terms of anaerobic capacity and energy metabolism Individual and/or population susceptibility may be one factor responsible for adopting pinitol supplementation.

• Journal of Biomedical Engineering Research
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• v.33 no.3
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• pp.155-162
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• 2012

Devices to measure the blood pressure of patients are being used without any calibration in a hospital. It is an important to show consistent values when any medical devices measure the same patients regardless they are sphygmomanometer or fully automatic electronic blood pressure meter. We compared sphygmomanometer and fully automatic electronic blood pressure meters with standard digital blood pressure monitor (SDBPM) to evaluate the consistency of the small healthy subjects. We measured the blood pressure from six healthy subjects (three of 20~40 years and three of 40~60 years old). Two sphygmomanometer and two fully automatic electronic blood pressure meters were used and compared with the SDBPM. Blood pressures measured from right and left arms each and were compared. All six healthy subjects showed normal blood pressure values. In general, left blood pressure values showed higher values than right side. Comparing SDBPM, with the other monitors, the systolic pressure showed ${\pm}$ 34.8% difference and ${\pm}$ 33.3% for the diastolic pressure. Correlation between SDBPM and Sphygmomanometer was 0.59~0.71, and 0.50~0.70 for fully automated digital BP monitors. It fell in grade-D when we apply the BHS(British hypertension society). AAMI(American association for the advancement of medical instrumentation) also showed unsatisfactory results for the mean value (${\leq}$ 5 mmHg) and standard deviation (${\leq}$ 8 mmHg). We tested sphygmomanometer and fully automatic electronic blood pressure meters and compared with a standard digital blood pressure monitor. All devices showed inconsistent blood pressures. A reliable calibration system is highly needed for all devices in all hospitals.