• Title/Summary/Keyword: Health risks

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A study of the Guidelines for Investigation and Management of Uterine Myomas with Korean Medicine Therapies in Korea (자궁근종의 한의학 연구 경향과 임상적 접근에 관한 연구)

  • Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
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    • v.19 no.2
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    • pp.240-260
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    • 2006
  • Purpose : The objective of this study is to serve guidelines for the investigation and management of uterine myomas with KM therapies. Methods : English-language articles from PubMed and Korean-language articles from the database of the journal of oriental gynecology were reviewed from 2000 to 2005, using the key words 'uterine myoma', 'uterine leiomyoma', 'fibroid', 'uterine artery embolization', 'endometrial ablation', 'myomectomy', and jagungguenjong(子宮筋腫)'. Results and Limits : The areas of clinical practices considered in formulating this guideline are assessment, KM therapies, medical treatments, myolysis, selective artery occlusion, endometrial ablation and surgical therapies including myomectomy and hysterectomy. Implementation of this guideline would optimize the decision-making process of women with uterine myomas and further investigation or therapy of their KM doctors. But we don't have abundant evidences of clinical trials of uterine myoma treated with KM therapy, though we treat or manage that with every-day clinical practices. Moreover cultural gaps between Korea and other western countries make many differences in the attitude to surgical therapies, especially hysterectomy. So it is very difficult to compare W therapies with other therapies. Moreover it is much difficult to estimate cost-effectiveness and benefit of those therapies in QOL. Conclusions : The majority of uterine myoma is asymptomatic and will not require any intervention or further investigation. But unmarried women who wish to marry and get pregnant want to find safe therapy for their asymptomatic uterine myomas. In that case, most of the patients prefer non-surgical therapy to surgical therapy. So KM herbal medicinal therapy is a good alternative method for those patients. For the symptomatic myomas, hysterectomy offers a definitive solution. However, it is not the best solution for women who wish to preserve their uterus. So KM therapy is a good alternative for them. But the predicted benefits of alternative therapies including KM therapy must be carefully weighed against the Possible risks of these therapies. To improve the quality of life of both women with asymptomatic and symptomatic myomas, selecting and treating patients should be done carefully. Moreover, the effect of KM therapy has to evaluated, comparing the possible situation without treatment and the benefit of constant treatment as a health-care system.

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Dietary Aloe Reduces Adipogenesis via the Activation of AMPK and Suppresses Obesity-related Inflammation in Obese Mice

  • Shin, Eun-Ju;Shin, Seul-Mee;Kong, Hyun-Seok;Lee, Sung-Won;Do, Seon-Gil;Jo, Tae-Hyung;Park, Young-In;Lee, Chong-Kil;Hwang, In-Kyeong;Kim, Kyung-Jae
    • IMMUNE NETWORK
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    • v.11 no.2
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    • pp.107-113
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    • 2011
  • Background: Metabolic disorders, including type II diabetes and obesity, present major health risks in industrialized countries. AMP-activated protein kinase (AMPK) has become the focus of a great deal of attention as a novel therapeutic target for the treatment of metabolic syndromes. In this study, we evaluated whether dietary aloe could reduce obesity-induced inflammation and adipogenesis. Methods: Male C57BL/6 obese mice fed a high-fat diet for 54 days received a supplement of aloe formula (PAG, ALS, Aloe QDM, and Aloe QDM complex) or pioglitazone (PGZ) and were compared with unsupplemented controls (high-fat diet; HFD) or mice fed a regular diet (RD). RT-PCR and western blot analysis were used to quantify the expression of obesity-induced inflammation. Results: Aloe QDM complex downregulated fat size through suppressed expression of scavenger receptors on adipose tissue macrophages (ATMs) compared with HFD. Both white adipose tissue (WATs) and muscle exhibited increased AMPK activation through aloe supplementation, and in particular, the Aloe QDM complex. Obesity-induced inflammatory cytokines (IL-$1{\beta}$ and -6) and $HIF1{\alpha}$ mRNA and protein were decreased markedly, as was macrophage infiltration by the Aloe QDM complex. Further, the Aloe QDM complex decreased the translocation of NF-${\kappa}B$ p65 from the cytosol in the WAT. Conclusion: Dietary aloe formula reduced obesity-induced inflammatory responses by activation of AMPK in muscle and suppression of proinflammatory cytokines in the WAT. Additionally, the expression of scavenger receptors in the ATM and activation of AMPK in WAT led to reduction in the percent of body fat. Thus, we suggest that the effect of the Aloe QDM complex in the WAT and muscle are related to activation of AMPK and its use as a nutritional intervention against T2D and obesity-related inflammation.

Evaluation of Excess Lung Cancer Risk in Korean due to Indoor Exposure to Natural $^{222}Rn$ Progenies (한국인의 실내 라돈-222 자핵종 피폭으로 인한 초과 폐암위험)

  • Chang, Si-Young;Ha, Chung-Woo;Lee, Byung-Hun
    • Journal of Radiation Protection and Research
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    • v.17 no.1
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    • pp.57-70
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    • 1992
  • An excess risk of lung cancer mortality among Koreans, attributable to indoor $^{222}Rn$ daughters exposure, were quantitatively evaluated by applying a stochastic health risk projection model on the radiation exposure. The lung cancer rate in Korean males and females, based on the 1989 demographic data, were estimated to be $22.4/10^5-y\;and\;9.5/10^5-y$, respectively The lifetime baseline lung cancer risks, deduced from these rates, appeared to be 0.047 and 0.019 for males and females, respectively, and were lower than the corresponding 1984 values of 0.067 and 0.025 in the U.S.A. The excess risk coefficients, derived by modified relative risk projection model of the BEIR-IV Committee under the US National Academy of Science, per annual 1.0 WLM of exposure to indoor radon daughters were estimated to be 0.022/WLM for males, 0.009/WLM for females, and 0.017/WLM for both sexes. The resulting annual frequency of excess lung cancer mortality for the life expectancy in the Korean population appeared to be 230/10^6-WLM, which was an approximate median of $120{\sim}450/10^6-WLM$ reported so far in the world.

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Development of Climate Change Adaptation Plan for Kurunegala City, Sri Lanka (스리랑카 Kurunegala시의 기후변화 적응 계획 개발)

  • Reyes, Nash Jett DG.;Cho, Hanna;Geronimo, Franz Kevin F.;Jeon, Minsu;Kim, Leehyung
    • Journal of Wetlands Research
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    • v.21 no.4
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    • pp.354-364
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    • 2019
  • Sri Lanka is an island nation susceptible to climate-related disasters and extreme weather events. Kurunegala City is the developing capital city of the North-Western Province of Sri Lanka. Changes in rainfall patterns and a steadily increasing annual average temperature amounting to 0.69±0.37℃ were observed in the city area. Generally, urban areas are at risk due to the lack of climate change adaptation provisions incorporated in the development plans. This study was conducted to investigate the characteristics of Krunegala City, Sri Lanka and develop an appropriate climate change adaptation plan for the city. Site investigation and qualitative risk assessment were conducted to devise a plan relevant to the climate change adaptation needs of the city. Qualitative risk analyses revealed that drinking water, water resources, and health and infrastructure risks were among the major concerns in Kurunegala City. Low impact development (LID) technologies were found to be applicable to induce non-point source pollutant reduction, relieve urban heat island phenomenon, and promote sound water circulation systems. These technologies can be effective means of alleviating water shortage and reducing urban temperature. The measures and strategies presented in this study can serve as reference for developing climate change adaptation plans in areas experiencing similar adverse effects of climate change.

A Design of Secure Electronic Health Information Management Protocol in the Internet of Things Environment (사물 인터넷 환경에서 안전한 전자의료정보 관리 프로토콜 설계)

  • Park, Jeong Hyo;Kim, Nak Hyun;Jung, Yong Hoon;Jun, Moon Seog
    • KIPS Transactions on Computer and Communication Systems
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    • v.3 no.10
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    • pp.323-328
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    • 2014
  • ZigBee based on the most vulnerable part of u-Healthcare system that uses the ZigBee communication is the wireless section. ZigBee communication sectors to identify vulnerabilities in this paper, we propose to compensate. ZigBee has been raised from the existing vulnerabilities organize and ZigBee also uses the 64bit address that uniquely identifies a vulnerability that was defined as exposure. And to prevent the exposure of a unique identifying address was used to address a temporary identification. ZigBee security services, the proposed system during the Network Key for encryption only use one mechanism of Residential Mode is used. Residential Mode on all nodes of the entire network because they use a common key, the key is stolen, your network's security system at a time are at risk of collapse. Therefore, in order to guard against these risks to the security policy Network Key updated periodically depending on the method used to. The proposed evaluation and comparative analysis of the system were exposed in the existing system can hide the address that uniquely identifies a public key Network Key also updated periodically, so that leaks can occur due to reduced risk.

Constructing Topographies of EMF Risks from Underground Power Lines (전자파 위험 지형도의 상이한 구성: 지중 송전선로 위험 논쟁을 중심으로)

  • Kim, JooHui
    • Journal of Science and Technology Studies
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    • v.19 no.3
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    • pp.119-166
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    • 2019
  • The risk of electromagnetic field(EMF) from power lines has been heavily disputed whenever high-voltage power line towers were built in South Korea. Local communities and civic groups had regarded burying the lines in the ground as an alternative to building power line towers. In 2014, however, when an elementary school science teacher reported the results of EMF measurements over the underground power lines to the Asian Citizens' Center for Environment and Health (ACCEH), the risk controversy over underground power lines took a whole new turn. The level of EMF from underground power lines turned out to be higher, and therefore more harmful than that from power line towers. In the debates that took place from then on over the EMF risk, ACCEH and NIER(National Institute of Environmental Research) presented conflicting topographies of EMF risk. This paper examines measuring practices of ACCEH and NIER by analyzing the measuring sites, measuring devices, and measuring heights chosen by each organization. This paper further examines how ACCEH and NIER mobilized various standards(EMF exposure limit, measurement guideline, categorization of carcinogens) differently. This controversy on the EMF from underground power lines of Seoul has raised concerns on the non-thermal effects of EMF in the long-term exposure and has led people to question whether burying the power lines is the safe alternative to building power line towers. Furthermore, this suggests conflicting answers on whether Seoul, where 90 % of transmission lines were already buried, is a safely managed place or not.

Predictive model and quantitative microbial risk assessment of enterohemorrhagic Escherichia coli and Campylobacter jejuni in milk (우유에서 장출혈성 대장균과 캠필로박터균의 행동예측 모델 개발 및 정량적 미생물 위해성 평가 연구)

  • Dong, Jiaming;Min, Kyung Jin;Seo, Kun Ho;Yoon, Ki Sun
    • Korean Journal of Food Science and Technology
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    • v.53 no.5
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    • pp.657-668
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    • 2021
  • We prepared the growth and survival models of enterohemorrhagic Escherichia coli (EHEC) and Campylobacter jejuni in milk as a function of temperature and assessed the microbiological risks associated with the consumption of whole milk. EHEC and C. jejuni were not detected in whole milk (n=195) in the retail market. The minimum growth temperature of EHEC in milk was 7℃. The lag time of EHEC in whole milk was longer than that in skim milk. The survival ability of C. jejuni in milk was better at 4℃ than at 10℃. Lower delta values were observed in whole milk than in skim milk, indicating that C. jejuni survived better in skim milk. The probability of foodborne illness from whole milk consumption was 5.70×10-5 for EHEC and 9.86×10-9 for C. jejuni. Sensitivity analysis results show that the market temperature of EHEC and the dose-response model of C. jejuni are correlated with the probability of foodborne illness.

Appraisal of Guidelines for Research & Evaluation II Appraisal of Clinical Practice Guidelines for Traffic Injuries (Appraisal of Guidelines for Research & Evaluation (AGREE) II를 이용한 교통사고 상해증후군의 국내·외 기개발 임상진료지침의 평가)

  • Park, Kyeong-Won;Lee, Jun-Seok;Kim, Hyun-Tae;Park, Sun-Young;Heo, In;Shin, Byung-Cheul
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.129-143
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    • 2021
  • Objectives This study was aimed to evaluate clinical practice guidelines (CPGs) of traffic injuries, which has already been developed at domestic or outside of country, and to explore the Korean medical treatments included in the CPGs. Methods Twelve electronic databases (PubMed, Cochrane library, China National Knowledge Infrastructure [CNKI {Chinese Academic Journals, CAJ}], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS], KoreaMed, Korean Medical Guideline Information [KoMGI), National Guideline Clearinghouse [AHRQ], Core Outcome Measures in Effectiveness Trials Initiative Website [COMET], Turning Research into Practice [TRIP], The National Institute for Health and Care Excellence [NICE], and Medical Research Information Center [MedRIC]) up to July 2021 were searched. Only systematically developed CPGs for traffic injuries were selected and appraised. The appraisal was conducted by using Appraisal of Guidelines for Research & Evaluation (AGREE) II tool. Results Six CPGs were included and evaluated. All CPGs were appraised as highly recommended because they exceeded 60% in more than 4 among 6 domains of AGREE II, including domain of 'rigor of development', and 30% in the rest. Recommendations related to Korean medicine treatments such as on manual therapy related to Chuna were given in 6 CPGs, 4 for acupuncture, 1 for Qigong and 1 for Taping. Conclusions The 6 CPGs were developed up to now through a systematic development methodology and there were many recommendations for Korean medical treatments related to manual (Chuna) treatment, acupuncture and Qigong. However, the evidence for the side effects and risk factors of Korean medical treatments was scantly reflected in CPGs. Therefore, it is considered that balanced CPG with benefits and risks should be developed, covering Korean medical diagnosis, treatment and prognosis.

Mediating Effect of Attitude toward Advertisement on the Relationship between COVID-19 Involvement and Behavioral Intention of Social Distancing in Loss versus Gain Advertising Context (손실과 이득 메시지 프레이밍 광고상황에서 COVID-19에 대한 관여와 사회적 거리두기 실천의도와의 관계에 영향을 미치는 광고태도의 매개효과)

  • Choi, Ja In;Choi, Ja Yun
    • Journal of the Korea Convergence Society
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    • v.12 no.12
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    • pp.467-477
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    • 2021
  • Purposes of this study were to identify the relationship among involvement in COVID-19 (IiC), attitude toward advertisement (AtA), and behavioral Intention to social distancing (BItSD), and to investigate the mediating effect of AtA in a loss versus gain advertising context. The participants were 379 adults who have been consecutively living in Korea since January 2020. The participants were randomly assigned to one of two advertisements using an online survey system. We found that IiC affects BItSD since Korean adults recognize the risks and seriousness of COVID-19 infection or transmission through IiC. Induced positive attitudes or emotions through involvement in the COVID-19 preventive behaviors including social distancing and vaccination are helpful to increase the BItSD. Thus, health care and information providers should give an accurate message, which induces a positive attitude, to recognize that our world is a risk of the COVID-19.

Evaluation of Fire Investigation as the Separation Distances for Several Types of Insulation Panels (단열패널 종류별 이격거리에 따른 화재감식 평가)

  • Kim, Jeong-Hun;Kim, Da-Seul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.4
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    • pp.403-412
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    • 2021
  • Despite strengthening requirements for fire retardancy and applied buildings of insulation panels, the number of fires and influence of damage have increased. In this study, the thermal effects were evaluated as the separation distances, and three types of EPS panel, glass wool panel, and gypsum board panel were then selected. Temperature sensors on the panels were installed vertically from the ground. The fire source on the lamination layer of lumber was ignited by changes in the separation distances (0 cm, 25 cm, 50 cm) from the panels. The test results suggested that the maximum temperature was 349 ℃ in the EPS panel. The inside/outside shape changes were limited by the height of the low and middle positions until the critical point of a 25 cm separation distance. Furthermore, the combustion marks appeared after 500 s on average, and then the EPS panel with a high fire strength showed a broad "U type" pattern, glass wool panel, and gypsum board panel showed medium or narrow "V type" pattern. Therefore, the acquired data can provide valuable information for evaluating the fire risks and verifying fire investigation from buildings composed of these insulation panels.