• Korean Journal of Organic Agriculture
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• v.25 no.1
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• pp.113-124
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• 2017

Cotton aphid (Aphis gossypii) and green peach aphid (Myzus persicae) are serious pests damaging various crops including vegetables such as pepper, cucumber, and Chinese cabbage. We conducted a study to control two aphids with secondary metabolite of entomopathogenic fungus Beauveria bassiana. A B. bassiana was already selected as a high virulence isolate against cotton aphid and green peach aphid. The culture filtrate of the isolate showed high pathogenicity against both aphids as 100% mortality against cotton aphid 3 days after treatment and 99% against green peach aphid 5 days after treatment. A different fraction extracts with $CHCl_3$ : MeOH of B. bassiana culture filtrate (30:1, 50:1, 70:1, 90:1, 100:1; v/v) through silica gel column chromatography showed different control effect to aphids. Among them, 50:1 ($CHCl_3$ : MeOH) fraction had highest mortality as 77.3% and 75.4% against A. gossypii and M. persicae, respectively. A mixture of each fraction (1:1) had no synergistic effects because control effect of every mixture was lower than only 50:1 extract; for example, mortality of 50:1 + 70:1 showed $2^{nd}$ highest as 72% of cotton aphid and 70.2% of green peach aphid and other mixtures were lower than these values. In future we will study the identification and mass production of aphicidal compound isolated from 50:1 fraction to develop stable aphid control agent.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.34 no.4
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• pp.89-97
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• 2016

This study looked at the sacrifice space building in the Changbai Mountain area to a specific era in terms of the cultural landscape. The scared of Changbai Mountain how changes in history came despite the regime and national change, interpretation of the reason was the scared maintained. The results of this study are as follows. First, Replacement of the regime in the Republic of China in the Qing period, ethnic diversity, underwent a cultural acceptance. So Changbai Mountain nature of sacrifice, the divine subject has formed the changes. Second, the Qing Royal sacrifice space Wangji Temple(望祭殿) have formed a unique cultural space and the sacrifice of authoritative content with only space. The Republic of China period, a new folk beliefs were born between the defense in the face of the Han Chinese migration and settlement process. Build Sacrifice space of Rulai Temple(如來寺) and Shanshenlaobatou Temple(山神老把頭廟). Third, the spatial relationship between the priest and the Changbai Mountain area Wangji Temple(望祭殿) is the power of space as vertical space. Rulai Temple(如來寺), Shanshenlaobatou Temple(山神老把頭廟) is located in the Changbai Mountain and horizontal space was obedient to the space. Fourth, the sacrifice ritual Wangji Temple(望祭殿) of the Qing Dynasty is the only ritual sacrifice of satisfaction. It is cut off depending on the abolition of imperial power. Currently, public ritual sacrifice is commonplace rituals and sacrifices of the Qing Dynasty is only formally underway. In conclusion, as it has been maintained for the sanctity historically Changbai Mountain. Changbai Mountain sacrifice space was changing through the acceptance of the replacement of the regime and culture of ethnic offerings from a single culture of the Qing Dynasty. Currently, to form a sacrifice space and culture overlap through a mutually acceptable.

• Allergy, Asthma & Immunology Research
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• v.10 no.6
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• pp.698-715
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• 2018

Purpose: Hrd1 has recently emerged as a critical regulator of B-cells in autoimmune diseases. However, its role in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) remains largely unexplored. This study aimed to examine Hrd1 expression and B-cell accumulation and their possible roles in CRSwNP. Methods: Quantitative real-time polymerase chain reaction, immunohistochemistry, enzyme-linked immunosorbent assay and Western blotting were used to assess gene and protein expression in nasal tissue extracts. Cells isolated from nasal tissues and peripheral blood mononuclear cells were characterized by flow cytometry. Local antibody production was measured in tissue extracts with a Bio-Plex assay. Additionally, changes in Hrd1 expression in response to specific inflammatory stimuli were measured in cultured dispersed polyp cells. Results: Nasal polyps (NPs) from patients with eosinophilic CRSwNP (ECRS) had increased levels of Hrd1, B-cells and plasma cells compared with NPs from patients with non-eosinophilic CRSwNP (non-ECRS) or other control subjects (P < 0.05). The average Hrd1 levels in B-cells in NPs from ECRS patients were significantly higher than those from non-ECRS patients and control subjects (P < 0.05). NPs also contained significantly increased levels of several antibody isotypes compared with normal controls (P < 0.05). Interestingly, Hrd1 expression in cultured polyp cells from ECRS patients, but not non-ECRS patients, was significantly increased by interleukin-$1{\beta}$, lipopolysaccharide and Poly(I:C) stimulation, and inhibited by dexamethasone treatment (P < 0.05). Conclusions: Differential Hrd1 expression and B-cell accumulation between the ECRS and non-ECRS subsets suggests that they can exhibit distinct pathogenic mechanisms and play important roles in NP.

• Korean Journal of Soil Science and Fertilizer
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• v.44 no.3
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• pp.375-379
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• 2011

This study was conducted to evaluate the effect of rice cover crop cropping systems on rice root growth in a rice field as affected by conventional tillage without rice straw or green manure crop treatment (CTFS, check plot), no-tillage without cover crops (NTNT), no-tillage amended with rape (NTRA), no-tillage amended with rye (NTRY), no-tillage amended with hairyvetch (NTHV), and no-tillage amended with Chinese milk vetch (NTCM). In 0-5 cm soil depth, dry weight of root in NTRS ($128g\;m^{-2}$) was significantly higher than in the other plots (p<0.05) at harvesting stage. In addition, content of active organic matter at 0-5 cm soil depth was $1,684g\;m^{-2}$ in NTCM, $1,309g\;m^{-2}$ in NTRA, $1,295g\;m^{-2}$ in NTRS, $1,072g\;m^{-2}$ in NTRY, $917g\;m^{-2}$ in NTHV, $434g\;m^{-2}$ CTFS, and $426g\;m^{-2}$ in NTNT treatment. In no-tillage rice cover crop cropping system, our findings suggest that NTRS and NTCM should be enhanced root growth and active organic matter in paddy field.

• Journal of Technology Innovation
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• v.28 no.4
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• pp.127-150
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• 2020

The World Health Organization (WHO) declared the third pandemic in history after the Hong Kong flu and swine flu. The outbreak of Corona 19 dramatically reduced exchanges between countries, while rapid contagion created a time gap in economic fluctuations by country. In January 2020, the trade dispute between the US and China entered into a consensus phase, but the economic decoupling phenomenon caused by Corona 19 made it difficult for China to balance trade with the US and made it difficult to comply with the terms of the trade dispute agreement between the US and China. President Trump attributed the responsibility for the spread of Corona 19 to China, and pointed out that the cause of the economic downturn was the infringement of Chinese trade secrets and illegal copies, and protectionism arose. As a result, China protested fiercely, and the conflict with the United States deepened. The US has declared trade sanctions on Huawei and SMIC, which are key companies in China's semiconductor industry, and is predicting the risk of a disconnection of the semiconductor value chain between the US and China. The separation of the value chain of the semiconductor industry has the potential to have a big impact on the semiconductor industry, a structure that is highly specialized and monopolized by certain countries and companies in the value chain. This paper aims to deal with the risk of disconnection in the semiconductor value chain between the US and China reignited by Corona 19, the impact and change of the global semiconductor industry value chain, and the response strategies of Korean semiconductor companies.

• Korea Science and Art Forum
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• v.37 no.5
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• pp.239-248
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• 2019

This study started from the need to improve one of shortcomings of synthetic PVAc adhesives - potential physical harm and environmental hazards to the workers or their users. As a matter of fact, PVAc adhesives are currently mainly used because of their convenience and economy for the production of woodcrafts. The purpose of this study was to develop natural adhesives through research on natural adhesives in step with the current increase of societal attention to environmental friendliness and rapid surge in their demand in the face of such problems. So, the study attempted research on the bases to develop natural adhesives for woodcraft, using cellulose extracts from wood - natural adhesive material. The findings of the study were as follows. Firstly, natural adhesives showed the improved effect in the field of adhesive strength, a basic physical property by 0.2 - 4 times compared with the existing materials and the study confirmed they had the similar or stable pH value. Besides, they had good reversibility, demonstrating their basic physical property as a natural adhesive for woodcraft. While, their durability to ultraviolet ray degradation also showed an excellent result value being better by 1.5 - 8.5 times than the existing materials. The study expects natural adhesives with improved and better performances compared with the existing materials could be developed, if further research on adhesive strength, antibiosis, conservative property were to continue by developing refinery technology for cellulose extracts from wood and rendering the functionality to them.

• The Plant Pathology Journal
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• v.35 no.4
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• pp.381-388
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• 2019

For several years, temperatures in the Korean peninsula have gradually increased due to climate change, resulting in a changing environment for growth of crops and vegetables. An associated consequence is that emerging species of insect vector have caused increased viral transmission. In Jeju Island, Korea, occurrences of viral disease have increased. Here, we report characterization of five newly collected turnip mosaic virus (TuMV) isolates named KBJ1, KBJ2, KBJ3, KBJ4 and KBJ5 from a survey on Jeju Island in 2017. Full-length cDNAs of each isolate were cloned into the pJY vector downstream of cauliflower mosaic virus 35S and bacteriophage T7 RNA polymerase promoters. Their fulllength sequences share 98.9-99.9% nucleotide sequence identity and were most closely related to previously reported Korean TuMV isolates. All isolates belonged to the BR group and infected both Chinese cabbage and radish. Four isolates induced very mild symptoms in Nicotiana benthamiana but KBJ5 induced a hypersensitive response. Symptom differences may result from three amino acid differences uniquely present in KBJ5; Gly(382)Asp, Ile(891)Val, and Lys(2522)Glu in P1, P3, and NIb, respectively.

• Korean Journal of Acupuncture
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• v.36 no.1
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• pp.36-43
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• 2019

Objectives : Carbon dioxide ($CO_2$) laser, a high power laser has been used for pain management, dermatology, and surgery and laser acupuncture and moxibustion as well, since it had been oscillated in 1964 at Bell Telephone Laboratories in the US. The purpose of this study is to investigate the history of $CO_2$ laser acupuncture through reviewing studies published in early stage of laser medicine. Methods : To investigate the early history of $CO_2$ laser acupuncture, studies were searched in the electronic databases, including PubMed, ScienceDirect, CNKI, Wanfang, J-STAGE, CiNii, KTNP, and OASIS, since 1964. Articles in English, Chinese, Japanese and Korean were included, and there were no limitations in literature types such as reviews, essays, clinical trials, animal experiments and veterinary research. Results : We found that the first $CO_2$ laser application to acupoints was done by a research team in Shanghai in 1976. They used $CO_2$ laser for acupuncture treatment and it was also the first laser acupuncture treatment in China. Since the first case report of $CO_2$ laser for leukopenia, it has been applied to various diseases in China, Korea, Japan and other western countries. It has been widely applied in the fields of dentistry and veterinary medicine, as well as clinical applications. Conclusions : Not only $CO_2$ laser can be used as laser acupuncture by stimulating the acupoints and meridians, but also can produce moxibustion effect by using heat stimulus. Therefore, it is expected that it will be used in various clinical fields in the future.

• Korean Journal of Heritage: History & Science
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• v.41 no.1
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• pp.57-78
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• 2008

According to the previous studies about Shilla's cremate grave, in the process of importing the cremate grave, there has been correlation with Chinese Buddhism, and there have been a lot of mentions about the change of the grave, Yinwha(Stamp) patterns and its existence, and about the characteristics of the vessels to contain the bones. The cremate grave is categorized into two-parts type and mono-type, depending on the dead person. The cremate graves that are in local areas such as Wang-Gyeong, show difference in types. The typical vessel to contain the bones, called "Yeongyeol Gori Yoogaeho" is again proved to have existed from A.D 8c. ~ A.D 9c., judging from the Yinwha pattern stamp's existence. Yet, the Yeongyeol Gori Yoogaeho from 9th century used the patternless pottery, also seen from the Won-wha 10 yeon-myeong cremate grave. Due to the prosperity of Buddhism, when the "Mukuchonggwang Taranikyong(Sutra)", translated into Han language in 704 at Dang, was imported into Shilla, the funeral ceremonies of Shilla people changed from making cremate graves with vessels or scattering the bones in oceans, into building stupas in temples with hopes and wishes to bring oneself and family's fortune and the next life of the dead. As a result, the meaning of "Grave" disappeared for the cremate graves, and rather the ceremony changed into scattering bones and wishing fortunes for the dead person. In other words, the ancestor-worship ceremony which was focused on the tomb changed into commemorating the ancestors and wishing individual fortunes by the religious assembly in temples and the building process of stupas. In conclusion, this social change was the cause of the extinction of stone chamber with tunnel entrance and the tombs such as cremate grave.

• The Journal of Korean Medicine
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• v.40 no.1
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• pp.153-173
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• 2019

Objectives: This study aimed to ascertain what should be considered in the "Guideline for Clinical Trials with Herbal Medicinal Products for Lung Cancer" by analyzing the existing guidelines and clinical trials. Methods: The committee searched guidelines and clinical trials about herbal medicine for lung cancer. The searched trials were analyzed in terms of inclusion and exclusion of participants, intervention, comparator, outcomes and trial design. Then, we compared the results of our analysis with the guidelines to identify the issues we will have to consider when making the "Guideline for Clinical Trials with Herbal Medicinal Products for Lung Cancer". Several guidelines for anti-tumor agents and clinical trials with herbal medicine were searched on the national institution homepage. The search terms were as follows: 'lung neoplasm', 'herbal medicine', 'Medicine, Korean traditional', 'Medicine, Chinese Traditional' etc. Results: There was no guideline for clinical trial with herbal medicine for lung cancer. In addition, 7 articles were searched through database searching. All the participants had non-small cell lung cancer. The type of intervention was decoction. Comparators included conventional treatments such as chemotherapy. The outcome measurements used in the studies were quality of life, tumor response, and survival duration, etc. Safety was evaluated by recording adverse events and blood test. Conclusions: Findings were made by reviewing existing guidelines and comparing them with clinical trials for lung cancer and herbal medicinal products. These results will be utilized in the development of "Guideline for Clinical Trials with Herbal Medicinal Products for Lung Cancer".