• Title/Summary/Keyword: Half-normal model

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Geomorphic Variables Influential to Develop Erosional Characteristics (산지사면의 침식에 영향을 주는 지형인자에 관한 연구)

  • Yoo-Jeong Hwang
    • Journal of the Korean Geographical Society
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    • v.33 no.3
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    • pp.365-376
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    • 1998
  • The goal of this study is to find the geomorphic variables contolling gully development on hillslopes following deforestation. Two possible geomorphic processes, surface erosion and mass movement were reviewed to compare the characteristics and geomorphic variables involved. The research objective in this paper is to find the variables and the statistical model which can explain gully density in the study area. Gully density was selected as a response variable. For log gully density, the best subset regression was found to have the variables such as area, surface length, and surface width. Log area is the most significant predictor. Even with several outliers, the normal probability plot of the residuals from this regression looks straight. So, area, surface length, and surface width explain half of the variance in gully density.

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Association Between Gastric Emptying Time and Incidence of Cardiovascular Diseases in Subjects With Diabetes

  • Park, Hyung-Min;Park, Seon-Young;Chung, Jin Ook;Cho, Dong Hyuk;Park, Chang-Hwan;Kim, Hyun-Soo;Chung, Dong Jin;Choi, Sung-Kyu;Rew, Jong-Sun;Chung, Min Young
    • Journal of Neurogastroenterology and Motility
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    • v.25 no.3
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    • pp.387-393
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    • 2019
  • Background/Aims Delayed gastric emptying (GE) is associated with high morbidity and mortality in subjects with diabetes. The aim of this study is to investigate associations between GE time and the major cardiovascular events (coronary heart diseases and ischemic stroke) in diabetic subjects with upper gastrointestinal (UGI) symptoms. Methods Among 259 subjects with chronic UGI symptoms who underwent gastric emptying study (GES) over 13 years, 122 diabetic subjects without gastric surgery and/or rapid GE were enrolled in this study. We also gathered data about baseline demographics, clinical characteristics, estimated GE half-time (GE T½) and incidence of cardiovascular events following GES. Results The mean age of subjects was 64.0 ± 17.4 years. There were 86 women and 104 subjects with type 2 diabetes. There were 52 (42.6%) subjects with normal GE, 50 (41.0.%) subjects with mild delayed GE, and 20 (16.4%) subjects with marked delayed GE. During follow-up (median, 207 weeks), cardiovascular events occurred in 7 (13.5%) subjects with normal GE, 4 (8.0%) subjects with mild delayed GE and 7 (35.0%) subjects with marked GE (P = 0.015). Univariate analysis showed that GE T½ was significantly associated with incidence of cardiovascular events (crude OR, 1.74; 95% CI, 1.12-2.69; P = 0.014). In a multivariate model, association between GE T½ and incidence of cardiovascular events remained statistically significant after adjustment for baseline characteristics and comorbidities (adjusted OR, 1.94; 95% CI, 1.21-3.12; P = 0.006). Conclusion A delay of GE was associated with an increased incidence of cardiovascular events in diabetic subjects with chronic UGI symptoms.

An Application of Design of Experiments for Optimization of MOF-235 Synthesis for Acetylene Adsorption Process (아세틸렌 흡착공정용 MOF-235 합성 최적화를 위한 실험 계획법 적용)

  • Cho, Hyungmin;Yoo, Kye Sang
    • Applied Chemistry for Engineering
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    • v.31 no.4
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    • pp.377-382
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    • 2020
  • A sequential design of experiments was employed to optimize MOF-235 synthesis for acetylene adsorption process. Two experimental designs were applied: a two-level factorial design for screening and a central composite design, one of response surface methodologies (RSM). In this study, 23 factorial design of experiment was used to evaluate the effect of parameters of synthesis temperature and time, and also mixing speed on crystallinity of MOF-235. Experiments were conducted 16 times follwing MINITAB 19 design software for MOF-235 synthesis. Half-normal, pareto, residual, main and interaction effects were drawn based on the XRD results. The analysis of variance (ANOVA) of test results depicts that the synthesis temperature and time have significant effects on the crystallinity of MOF-235 (response variable). After screening, a central composite design was performed to optimize the acetylene adsorption capacity of MOF-235 based on synthesis conditions. From nine runs designed by MINITAB 19, the result was calculated using the second order model equation. It was estimated that the maximum adsorption capacity (18.7 mmol/g) was observed for MOF-235 synthesized at optimum conditions of 86.3 ℃ and 28.7 h.

Abundance Estimates of the Minke Whale, Balaenoptera acutorostrata, in the East Sea, Korea (한국 동해 밍크고래 Balaenoptera acutorostrata의 자원개체수 추정)

  • Park, Kyum-Joon;An, Yong-Rock;Kim, Zang-Geun;Choi, Seok-Gwan;Moon, Dae-Yeon;Park, Ji-Eun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.6
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    • pp.642-649
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    • 2009
  • Line transect data from sighting surveys conducted in the East Sea, Korea in 2000, 2002, 2003, 2005 and 2006 were analysed to estimate densities and numbers of minke whale. The half-normal model was fit to the survey in 2000 and the uniform model was the most fitable to the survey in 2002 and 2006, and the surveys in 2003 and 2005 were fit by the hazard-rate model. The estimated density of minke whale in the survey in 2000 was estimated as 0.026 individuals/$km^2$ (CV=0.409; 95% CI 0.011-0.065) and was higher than the survey in 2002 estimated as 0.018 individuals/$km^2$ (CV=0.329; 95% CI: 0.009-0.034). The estimated density of minke whale in the survey in 2003 was estimated as 0.033 individuals/$km^2$ (95% CI: 0.008-0.139) with the highest CV 0.760. The highest density was estimated in the survey in 2005 with 0.053 individuals/$km^2$ (95% CI: 0.020-0.141). The Lowest CV (0.306) was estimated in the survey in 2006 with 0.025 individuals/$km^2$ (95% CI: 0.014-0.046). A total of 500 bootstrap samples were generated within each stratum. Density, CV and 95% CI of each surveys were increased than analytic results except the survey in 2003. There were no increasing or decreasing annual trends in the density of minke whales observed during the study period. A long-term monitor and survey is needed to assess project minke whale abundance in the East Sea.

Study on Usefulness of Entrance Surface Dose (ESD), Entropy Analysis Method to Evaluate Ionization Chamber Performance and Implementation of Optimal Chamber Combination Model when using Automatic Exposure Control (AEC) Device in Digital Radiography (DR) (디지털 방사선 시스템(DR)의 자동노출제어장치 이용 시 이온 챔버의 성능 평가를 위한 엔트로피 분석법의 유용성과 최적의 챔버 조합 모델 구현 연구)

  • Hwang, Jun-Ho;Choi, Ji-An;Lee, Kyung-Bae
    • Journal of the Korean Society of Radiology
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    • v.14 no.4
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    • pp.375-383
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    • 2020
  • This study aimed to propose a methodology for quantitatively analyzing problems resulting from the performance and combination of the ionization chamber when using an automatic exposure control (AEC) and to optimize the performance of the digital radiography (DR). In the experimental method, the X-ray quality of the parameters used for the examination of the abdomen and pelvis was evaluated by percentage average error (PAE) and half value layer (HVL). Then, the stability of the radiation output and the image quality were analyzed by calculating the entrance surface dose (ESD) and entropy when the three ionization chambers were combined. As a result, all of the X-ray quality of the digital radiography used in the experiment showed a percentage average error and a half value layer in the normal range. The entrance surface dose increased in proportion to the combination of chambers, and entropy increased in proportion to the combination of ionization chambers except when three chambers were combined. In conclusion, analysis using entrance surface dose and entropy was found to be a useful method for evaluating the performance and combination problems of the ionization chamber, and the optimal performance of the digital radiography can be maintained when two or less ionization chambers are combined.

Survey of the use of statistical methods in Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • Choi, Yong-Geun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.44 no.1
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    • pp.25-28
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    • 2018
  • Objectives: This study aimed to describe recent patterns in the types of statistical test used in original articles that were published in Journal of the Korean Association of Oral and Maxillofacial Surgeons. Materials and Methods: Thirty-six original articles published in the Journal in 2015 and 2016 were ascertained. The type of statistical test was identified by one researcher. Descriptive statistics, such as frequency, rank, and proportion, were calculated. Graphical statistics, such as a histogram, were constructed to reveal the overall utilization pattern of statistical test types. Results: Twenty-two types of statistical test were used. Statistical test type was not reported in four original articles and classified as unclear in 5%. The four most frequently used statistical tests constituted 47% of the total tests and these were the chi-square test, Student's t-test, Fisher's exact test, and Mann-Whitney test in descending order. Regression models, such as the Cox proportional hazard model and multiple logistic regression to adjust for potential confounding variables, were used in only 6% of the studies. Normality tests, including the Kolmogorov-Smirnov test, Levene test, Shapiro-Wilk test, and $Scheff{\acute{e}}^{\prime}s$ test, were used diversely but in only 10% of the studies. Conclusion: A total of 22 statistical tests were identified, with four tests occupying almost half of the results. Adoption of a nonparametric test is recommended when the status of normality is vague. Adjustment for confounding variables should be pursued using a multiple regression model when the number of potential confounding variables is numerous.

Binding Modes of New Bis-Ru(II) Complexes to DNA: Effect of the Length of the Linker

  • Kwon, Byung-Hyang;Choi, Byung-Hoon;Lee, Hyun-Mee;Jang, Yoon-Jung;Lee, Jae-Cheol;Kim, Seog-K.
    • Bulletin of the Korean Chemical Society
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    • v.31 no.6
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    • pp.1615-1620
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    • 2010
  • Bis-[dipyrido[3,2-$\alpha$:2',3'-c]phenazine)$_2$(1,10-phenanthroline)$_2Ru_2$]$^{2+}$ complexes (bis-Ru(II) complexes) tethered by linkers of various lengths were synthesized and their binding properties to DNA investigated by normal absorption and linear dichroism spectra, and fluorescence techniques in this study. Upon binding to DNA, the bis-Ru(II) complex with the longest linker (1,3-bis-(4-pyridyl)-propane), exhibited a negative $LD^r$ signal whose intensity was as large as that in the DNA absorption region, followed by a complicate $LD^r$ signal in the metal-to-ligand charge transfer region. The luminescence intensity of this bis-Ru(II) complex was enhanced. The observed $LD^r$ and luminescence results resembled that of the [Ru(1,10-phenanthroline)$_2$ dipyrido[3,2-$\alpha$:2',3'-c]phenazine]$^{2+}$ complex, whose dipyrido[3,2-$\alpha$:2',3'-c]phenazine (dppz) ligand has been known to intercalate between DNA bases. Hence, it is conclusive that both dppz ligands of the bis-Ru(II) complex intercalate. The binding stoichiometry, however, was a single intercalated dppz per ~ 2.3 bases, which violates the "nearest binding site exclusion" model for intercalation. The length between the two Ru(II) complexes may be barely long enough to accommodate one DNA base between the two dppz ligands, but not for two DNA bases. When the linker was shorter (4,4'-bipyridine or 1,2-bis-(4-pyridyl)-ethane), the magnitude of the LD in the dppz absorption region, as well as the luminescence intensity of both bis-Ru(II) complexes, was half that of the bis-Ru(II) complex bearing a long linker. This observation can be elucidated by a model whereby one of the dppz ligands intercalates while the other is exposed to the aqueous environment.

Optical Monitoring of Tumors in BALB/c Nude Mice Using Optical Coherence Tomography

  • Song, Hyun-Woo;Lee, Sang-Won;Jung, Myung-Hwan;Kim, Kye Ryung;Yang, Seungkyoung;Park, Jeong Won;Jeong, Min-Sook;Jung, Moon Youn;Kim, Seunghwan
    • Journal of the Optical Society of Korea
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    • v.17 no.1
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    • pp.91-96
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    • 2013
  • We report a method for optical monitoring of tumors in an animal model using optical coherence tomography (OCT). In a spectral domain OCT system, a superluminescent diode light source with a full width of 66 nm at half maximum and peak wavelength of 950 nm was used to take images having an axial resolution of 6.8 ${\mu}m$. Cancer cells of PC-3 were cultured and inoculated into the hypodermis of auricle tissues in BALB/c nude mice. We observed tumor formation and growth at the injection region of cancer cells in vivo and obtained the images of tumor mass center and sparse circumferences. On the $5^{th}$ day from an inoculation of cancer cells, histological images of the tumor region using cross-sectional slicing and dye staining of specimens were taken in order to confirm the correlation with the high resolution OCT images. The OCT image of tumor mass compared with normal tissues was analyzed using its A-scan data so as to obtain a tissue attenuation rate which increases according to tumor growth.

Maillard Reaction in an Intermediate Moisture Model Food System (중간수분식품 모델계에서의 마이야르 반응에 관한연구)

  • Kim, Yun-Ji;Choi, Hyeong-Taeg;Yu, Ju-Hyun;Oh, Doo-Hwan
    • Korean Journal of Food Science and Technology
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    • v.19 no.2
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    • pp.113-118
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    • 1987
  • An intermediate moisture model food system was used to investigate the effects of water activity (Aw), temperature, pH and polyethyleneglycol (PEG) on the Maillard reaction. The initial molar ratio of glucose to lysine was varied from one half to four. The maximum Maillard reaction was obtained from an initial glucose/lysine molar ratio of approximately three. The rate of Maillard reaction showed a maximum in the range of water activity of a normal intermediate moisture food. 'the model food system was prepared to hold water activity range of 0.47-0.84 and the samples were held at various temperatures. The maximum browning rate occurred at an Aw value of approximately 0.89 at $40^{\circ}C$ and $60^{\circ}C$, 0.74 at $30^{\circ}C$ and 0.67 at $20^{\circ}C$, respectively. The Arrhenius activiation energies for nonenzymatic browning pigment production were 18.03, 15.18 and 9.90 Kcal/mole for the sample with Aw 0.84, 0.74 and 0.67. When the pH of the model system was increased, a significant increase in the browning reaction was observed. On the inhibitive effects of PEG, the higher degree of polymerization, the more inhibition of browning reaction.

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An Experimental Investigation on the Flow Field around the Wing Having a Circular Damage Hole (원형 손상 구멍이 있는 날개 주위 유동장에 관한 실험적 연구)

  • Lee, Ki-Young
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.36 no.10
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    • pp.954-961
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    • 2008
  • An experimental study has been conducted to investigate the flow field around the wing having a circular damage hole. The damage was represented by a circular hole passing through the model with 10% airfoil chord diameter and normal to the chord. The hole was centered at quarter or half chord. The PIV flow fields and static pressure measurements on the wing upper and lower surface were carried out at Rec=2.85×105 based on the chord length. The PIV results showed the two types of flow structures around a damage hole were formed. The first one was a weak jet that formed an attached wake behind the damage hole. The second one resulted from increased incidence; this was a strong jet where the flow through the hole penetrates into the free-stream resulting in extensive separation of oncoming boundary layer flow and development of a separated wake with reverse flow. The surface pressure data showed a big pressure alteration near the circular damage hole. The severity of pressure alteration was increased as a damage hole located nearer to the leading edge.