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A Rare and Often Unrecognized Brain Meningitis and Hepatopneumonic Congestion are a Major Cause of Sudden Death in Somatic Cloned Piglets

  • 박미령;조성근;임여정;박종주;김진회
    • Proceedings of the KSAR Conference
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    • 2003.06a
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    • pp.18-18
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    • 2003
  • In human, sudden infant death syndrome(SIDS) is synonyms for the sudden, unexpected and unexplained death of an infant. The incidence of SIDS has been estimated to be from 1 to 3%. Cloning has a relatively high rate of late abortion and early postnatal death, particularly when somatic cells are used as donors of nuclei and rates as high as 40 to 70% have been reported. However, the mechanisms for SIDS in cloned animals are not known yet. To date, few reports provide detailed information regarding phenotypic abnormality of cloned pigs. In this study, most of the cloned piglets were alive at term and readily recovered respiration. However, approximately 82% of male cloned piglets (81/22) died within a week after birth. Significant findings from histological examinations showed that 42% of somatic cloned male piglets died earlier than somatic cloned female piglets, most probably due to severe congestion of lung and liver or neutrophilic inflammation in brain, which indicates that unexpected phenotypes can appear as a result of somatic cell cloning. No anatomical defects in cloned female piglets were detected, but three of the piglets had died by diarrhea due to bacterial infection within 15 days after birth. Although most of male cloned piglets can be born normal in terms of gross anatomy, they develop phenotypic anomalies that include leydig cell hypoplasia and growth retardation post-delivery under adverse fetal environment and depigmentation of hair- and skin-color form puberty onset. This may provide a mechanism for development of multiple organ system failure in some cloned piglets. Th birth weights of male cloned pig in comparison with those of female cloned piglets are significantly reduced(0.8 vs 1.4kg) and showed longer gestational day(120 vs 114). In conclusion, brain meningitis and hepatopneumonic congestion are a major risk factor for SIDS and such pregnancy in cloned animals requires close and intensive antenatal monitoring.

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A study on Living Culture of Korea through accounting records written by Song, Whasun at Hongcheon-Up in early 20th century (홍천읍 송화선(宋化善) 장기(掌記)를 통해 본 20세기 초 한국의 생활 문화 연구)

  • Cho, Imsun;Lee, Eunjin
    • Journal of Fashion Business
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    • v.21 no.1
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    • pp.148-165
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    • 2017
  • An assortment of daily supplies have been documented in and accounting book that Hwa-sun Song, a wholesale dealer in Hongcheon, Gangwon-do, sent to Young-hui Sin, a customer. This study analyzed a total of 163 documentations in the accounting book between 1910 to 1916, which includes types of daly supplies, trading volume, and prices, maintained accounting between. Consequently, we are able to indentify companies that produced the applicable goods, names of products, units by which goods were counted, and the lowest and highest prices prevailing, along with kinds of goods patronized in everyday life in Hongcheon in the early 20th century. Paper had the maximum trading volume. The second, most traded were cigarettes, a symbol of the new culture. These were traded under various brand names, such as Kkotpyo, Guksyu, Sanhopyo, Syonghak, and Joil. Foodstuffs, were the third most traded items, including fish, fruits, sugar, Waeddeok, Chilwaeddeok, Color candies and Okchyun candies. Our results indicate that the snack food business had developed since the 19th century. Lighting equipment, oil, candles, matches as well as traditional oil lamps and flints cornered the fourth largest stock being traded. Medications were fifth, with prescriptions written for Insohwan, Hoechyungsan and Siungo, including quinine, a medicine for malaria. Other trades included kitchen appliances such as soup bowls, porcelain bowls, kettles, and drinking cups, and a variety of daily supplies such as mirrors, mats, umbrellas, Geumjiwaemil, hair oil imported from Japan, and soap.

Histologic Changes of Rabbit Skin Induced by Progressive Tissue Expansion (Tissue Expansion이 가토의 피부에 미치는 조직학적인 변화)

  • Jeong, Jae-Ho;Kim, Ki-Yeol;Choi, See-Ho;Seul, Jung-Hyun
    • Journal of Yeungnam Medical Science
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    • v.5 no.2
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    • pp.25-30
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    • 1988
  • Soft-tissue expansion is a new surgical technique of providing donor tissue in modern reconstructive surgery. This technique provides a quantity of tissue of similar color, texture, and hair-bearing qualities for reconstruction of adjacent defects. It is known that the expanded skin shows several constant histologic changes including the increase in collagen fibers and vascularity within dermis, and thinning of subcutaneous tissue and dermis. In this study, the author observed serial histologic changes of rabbit skin induced by progressive tissue expansion upto excessive expansion of 6 times. The results are as follows : 1. Changes in the thickness of the epidermis was minimal until 3 times of expansion, but slight thinning was observed at excessive expansion state. 2. The thickness of the dermis was progressively decreased, and collagen fibers in the dermis was rapidly increased in early phase of expansion. 3. The vascularity in the dermis was also progressively increased. 4. The skin appendages showed no structural changes even in excessive expansion. 5. The panniculus carnosus showed no atrophic changes and the thickness was maintained in excessive expansion.

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Rooibos Extract Effect on the Seborrheic Scalp Improvement of Middle-Aged Men (루이보스 추출물이 중년 남성의 지루성 두피 개선에 미치는 효과)

  • Lee, Jong-Youl;Lee, Song-Jeong;You, Seon-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.7
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    • pp.311-318
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    • 2016
  • This study conducted a 4-week clinical trial on 30 males suffering from seborrheic dermatitis and hair loss symptoms to examine the effects of rooibos extract on the seborrheic dermatitis improvement of 30-50 year old middle aged males. The comparison group used shampoo with no rooibos extract while experiment group 1 used shampoo including rooibos extracts, and experiment group 2 used shampoo and scalp enhancer including the rooibos extracts. The results showed that there were no meaningful changes on the scalps of the comparison group while experiment group 2, which used both shampoo and scalp enhancer including rooibos, showed better improvement on seborrheic dermatitis than experiment group 1 which only used shampoo including rooibos. These results imply that shampoo and scalp enhancer including rooibos extracts effectively improve the oil-moisture balance on seborrheic dermatitis and effectively deals with scalp itchiness redness and the color tone of the scalp, suggesting its use in scalp cosmetics that include antioxidation activation elements, which are effective in improving seborrheic dermatitis.

A Study on Class Representation in Korean and Western Costume (우리나라와 서양 복식에 나타난 계층표식에 관한 연구)

  • 권현주;이순홍
    • Journal of the Korean Society of Costume
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    • v.50 no.4
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    • pp.147-164
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    • 2000
  • This thesis examines the origin, the change and the symbolic meanings of class representation, and offers a comparative study on the differences of class representation in the history of Korean and western costume on the basis of class representation methods and types shown from ancient times to 18C. In both eastern and western costume, the differences in status are commonly represented in the width and length of costume, color, textile, ornamental design, wearing, decoration, etc. The costume of noble class was wide and long, while that of common class was narrow and short so that it could be convenient for them to move around. Especially, from 16C to 18C in the west the costume of noble class was expanded to the extent that it was inconvenient for them to move around not only by skirt swelling by using hoop, but also by pad, ruff, lace, etc. This appears to show that they are not working class. Wearing and decoration of noble class were much more colorful, complicated and varied, while those of common class were simple and plain. In the west, the wearing of chiton and toga in Greece and Rome was different depending on social status. More specific look at the differences in class representation shown in the eastern and western costume reveals that the higher the rank, the more the women in both Gothic and Chosun period covered the body, thereby representing rank. In 18C, the women in both Rococo and Chosun period commonly showed excessive decoration and lavishness on their hair, and in this period the width of skirt was also commonly expanded to the longest extent, with a slight difference put aside.

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A Study on the Evolution of Image Making through Costumes in the '007' Film Series ('007' 시리즈 영화 의상의 시대별 이미지 연출에 관한 연구)

  • Jang, Sung-Eun
    • Journal of the Korean Society of Costume
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    • v.59 no.1
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    • pp.106-118
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    • 2009
  • This research is about the changes in the images of Bond and Bond Girl in '007' Series. And it examined through the social background of England from 1960s to 2000s and the costume in the film. The results were as follows: As the era of young fashion was opened after 1960, there was a big change, but Bond was expressed as a hero who had strong male chauvinism of the English aristocratic circles. However, after 1990s, he wore comfortable clothes and he underwent all sorts of hardships. On the other hand, Bond Girl had the image of a sexual target. However, after 1990s, she had sharp appearance and smart brain. Besides, she had professional ideas of a given work and she was changed into a healthy image. Second, Bond's job was an English secrete agent, but Bond Girl had no particular job in 1960s. In 1980s, various professional jobs appeared and in 1990s and 2000s, the professional job which was directly related with Bond's duties appeared. Third, Bond's upper class image was expressed by tuxedo, suit, black, gray, navy, beige, brown, and ivory. His hair was 2:8 parting or Dandy all black style produced his dignified and neat image. After 1990s, he often had casual dress, which created a comfortable image. Bond Girl was expressed feminine style by bikini, underwear, long dress, sky-blue, violet, black, simple costume. After 1990s, she wore a suite, one-piece, or a combat uniform, which showed her professionalism. especially Bond Girl's red dress was used as a psychological color to express temptation, enemy, and betray.

Clinical Applications of the Meridian Theory in the Point of Hyungsang Medicine (형상의학적(形象醫學的) 관점(觀点)에서 본 경락이론(經絡理論)의 임상활용(臨床活用))

  • Kang, Kyung-Hwa;Song, Choon-Ho;Kim, Hyung-Gyu;Lee, Yong-Tae
    • Korean Journal of Acupuncture
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    • v.21 no.1
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    • pp.149-173
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    • 2004
  • Objective & Methods : In the point of several medical books included 'Internal Classic' and Hyungsang medicine, the writer studied about meridian theory and it's disorders, after adapting to acupuncture and herb medicine. Results : 1. Dr. Jisan explained concretely physiological and pathological meridian appearances with using metaphor about phenomenons of nature and human living. 2. Shapes corresponding to meridian are considered as Yukkyunghyung formed by more or less of vigor and blood, and by tendency of up and down in eyes and nose, and also contained diseases of viscera and characters. 3. The colors connected with meridian are changed according to conditions, and meridian is seen through colors. And then colors is the properties of vital energy and symbol of spirit, that is expressed as aspect of essence, vigor, spirit and blood, as the original color of five viscera, as the colors of four seasons and as the colors of diseases. So the changes of feelings are appeared to meridian flow. 4. The method of examining pulse for meridian disorders is applied to Jisan diagram. Jisan diagram is devised from mutual communication of viscera and connection with inside and outside. It is conjugated widely in clinical examination to be distinguished into Dam-Bangkwang, into diseased part of viscera and into meridian. Also it is conjugated recuperation of diseases. 5. The meridian diseases are appeared all the distributed parts of meridian, especially skin, hair, eyebrow, and the ends of the extremities which are sensitive to stimulus. The causes are the disharmony between vital energy and blood and the discordance of six atmospheric variation. The symptoms are skinny aches, itching and eruption, etc. Conclusions : The acupuncture of Hyungsang medicine which utilizes classification of shapes, examining pulse according to Jisan diagram and demonstration of symptoms, is very effective and required systematical study from now on.

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Unrecorded fern species from Korean flora: Thelypteris interrupta (Thelypteridaceae) and Dryopteris subexaltata (Dryopteridaceae) (한국산 미기록 양치식물 : 검은별고사리(처녀고사리과)와 계곡고사리(관중과))

  • Moon, Myung Ok;Kim, Chan Soo;Kang, Young Je;Kim, Chul Hwan;Sun, Byung-Yun
    • Korean Journal of Plant Taxonomy
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    • v.32 no.4
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    • pp.481-489
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    • 2002
  • Unrecorded fern species of Korean flora, Thelypteris interrupta (Willd.) K. Iwats. (Thelypteridaceae) and Dryopteris subexaltata (H. Christ) C. Chr. (Dryopteridaceae), were collected from Jeju island off the south coast of Korean peninsula and reported here. T. interrupta is most similar to T. acuminata (Houtt.) C. V. Morton in morphology, however, the two species are readily distinguishable by the plant color including rhizome, stipe base and spore, and the presence of glandular hair as well as the distribution pattern of sorus on lower leaf surface. D. subexaltata is also well distinguishable from its relatives, D. sparsa (D. Don) Kuntze, D. sabaei (Franch. & Sav.) C. Chr., and D. yakusilvicola Sa. Kurata by the presence of proliferation, shape of pinnae, distribution pattern of sori on lower leaf surface, and shape of indusium.

A Comparative Study on Korean and U.S. Emo Fashion (한국과 미국의 Emo Fashion Style에 관한 연구)

  • Park, Judy Joo-Hee;Ha, Ji-Soo
    • Journal of the Korean Society of Costume
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    • v.58 no.2
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    • pp.48-61
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    • 2008
  • This study aimed to examine emo fashion, a very recent music-related fashion trend spreading fast amongst youths, and understand emo ideas and methods of expression for a greater understanding of contemporary youth sub-cultures and fashion trends. Documentary research, positive research and in-depth interviews were used throughout the study. 4 Korean emo bands and 4 U.S. emo bands were selected based on music chart rankings, and a total of 37 photographs from the bands' Internet websites were selected, and their clothes shown in the photographs were examined. 5 Korean emo band musicians were subjects of in-depth interviews, and they were asked about their emo culture, music, fashion, ideas and styles, and photographs were taken of the subjects and evaluated, too. Lastly, Korean and U.S. emo kids were studied through photographs, and comparatively analyzed. Both Korean and U.S. emo musicians wore slim silhouettes, skinny jeans, t-shirts, sneakers, black, studded belts and plastic-framed glasses. Korean fashion expressed a less depressive atmosphere with color and other details compared to the United States, and did not prefer dark black eye make-up, which United States emo style appeared to express frequently. Korean musicians' emo fashion was closer to other youth fashions, whereas U.S. emo fashion included more formal styles such as ruffled shirts and pin-striped vests. Korean emo kids wore clothes not much different from most Korean youths, but U.S. emo kids wore a lot of eye make-up and black t-shirts with graphic or skull prints, and had more geometrical hair styles, as if cut at home. The reasons for such differences were found to be a longer emo music and culture history in the United States leading to more elaborate fashion expressions and a difference in the states of mind, such as Korea pursuing to express love, and the United States pursuing loneliness.

Hepatotoxicity Induced by Microcystin-LR in Rat

  • Kim, Bum-Seok;Cho, Jae-Woo;Kwon, Hyuk-Nyun;Blank, Ivar;Borisova, Irina;Ejaz, Sohail;Chekarova, Irina;Kwon, Jung-Kee;Lim, Chae-Woong
    • Toxicological Research
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    • v.22 no.4
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    • pp.375-380
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    • 2006
  • Microcystin-LR (MC-LR) is a cyanobacterial hepatotoxin mainly produced by Microcystis aeruginosa. The current study examined the effects of a single intraperitoneal dose of MC-LR in rats. Female Sprague-Dawley rats were intraperitoneally injected with MC-LR ($100{\mu}g/kg$ body weight) and they were sacrificed at 0, 20, 40, 80, 160 min, or 12 h after injection. Clinically, animals showed lethargy and had ruffled hair beginning at 40 min post injection. In the gross findings, liver was enlarged and its color was changed into dark red beginning at 40 min post injection. Microscopically, dissociation of centrilobular hepatocytes and hemorrhage was observed in the hepatic central legions and such pathological changes were then extended to the portal regions of liver by time course manner. Interestingly at 80 min after MC-LR injection, the entrapped eosinophilic materials that may be necrotic fragments of dissociated hepatocytes were found in the capillaries of lung and renal glomerulus. Ultrastructurally, microvilli of the hepatocytes were disrupted or lost at all time points. Furthermore, the Disse space and gap junctions were widened beginning at 40 min post injection. These results suggest that liver is the major target organ of MC-LR and isolated hepatocytes by the effects of such hepatotoxin may secondarily reduce the physiological function of lung and kidney.