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Prevalence of Senecavirus A in pigs from 2014 to 2020: a global systematic review and meta-analysis

  • Xuhua Ran;Zhenru Hu;Jun Wang ;Zhiyuan Yang ;Zhongle Li ;Xiaobo Wen
    • Journal of Veterinary Science
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    • v.24 no.3
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    • pp.48.1-48.13
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    • 2023
  • Background: Senecavirus A (SVA), a member of the family Picornaviridae, is newly discovered, which causes vesicular lesions, lameness in swine, and even death in neonatal piglets. SVA has rapidly spread worldwide in recent years, especially in Asia. Objectives: We conducted a global meta-analysis and systematic review to determine the status of SVA infection in pigs. Methods: Through PubMed, VIP Chinese Journals Database, China National Knowledge Infrastructure, and Wanfang Data search data from 2014 to July 26, 2020, a total of 34 articles were included in this analysis based on our inclusion criteria. We estimated the pooled prevalence of SVA in pigs by the random effects model. A risk of bias assessment of the studies and subgroup analysis to explain heterogeneity was undertaken. Results: We estimated the SVA prevalence to be 15.90% (1,564/9,839; 95% confidence interval [CI], 44.75-65.89) globally. The prevalence decreased to 11.06% (945/8,542; 95% CI, 28.25-50.64) after 2016. The highest SVA prevalence with the VP1-based RT-PCR and immunohistochemistry assay was 58.52% (594/1,015; 95% CI, 59.90-83.96) and 85.54% (71/83; 95% CI, 76.68-100.00), respectively. Besides, the SVA prevalence in piglet herds was the highest at 71.69% (119/166; 95% CI, 68.61-98.43) (p < 0.05). Moreover, our analysis confirmed that the subgroups, including country, sampling year, sampling position, detected gene, detection method, season, age, and climate, could be the heterogeneous factors associated with SVA prevalence. Conclusions: The results indicated that SVA widely exists in various countries currently. Therefore, more prevention and control policies should be proposed to enhance the management of pig farms and improve breeding conditions and the environment to reduce the spread of SVA.

A Prognostic Model To Predict Survival In Stage III Colon Cancer Patients Based on Histological Grade, Preoperative Carcinoembryonic Antigen Level and the Neutrophil Lymphocyte Ratio

  • Wuxiao, Zhi-Jun;Zhou, Hai-Yan;Wang, Ke-Feng;Chen, Xiao-Qin;Hao, Xin-Bao;Lu, Yan-Da;Xia, Zhong-Jun
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.747-751
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    • 2015
  • Background: Stage III colon cancer patients demonstrate diverse clinical outcomes. The aim of this study was to develop a prognostic model in order to better predict their survival. Materials and Methods: From 2004 to 2010, 548 patients were retrospectively analyzed, among whom 328 were defined as the study group and the remaining 220 served as a validation group. Clinico-pathologic features, including age, gender, histological grade, T stage, number of positive lymph nodes, number of harvest lymph nodes, pretreatment carcinoembryonic antigen (CEA) levels and pretreatment neutrophil lymphocyte ratio (NLR), were collected. Kaplan-Meier survival curves were used to detect prognostic factors and multivariate analysis was applied to identify independent examples on which to develop a prognostic model. Finally, the model was further validated with the validation group. Results: Histological grade (p=0.002), T stage (p=0.011), number of positive lymph nodes (p=0.003), number of harvested lymph nodes (p=0.020), CEA (p=0.005), and NLR (p<0.001) were found as prognostic factors while histological grade [RR(relative risk):0.632, 95%CI (Confidence interval) 0.405~0.985, p=0.043], CEA (RR:0.644, 95%CI:0.431~0.964, p=0.033) and NLR (RR:0.384, 95%CI:0.255~0.580, p<0.001) levels were independent. The prognostic model based on these three factors was able to classify patients into high risk, intermediate and low risk groups (p<0.001), both in study and validation groups. Conclusions: Histological grade, pretreatment CEA and NLR levels are independent prognostic factors in stage III colon cancer patients. A prognostic model based on these factors merits attention in future clinical practice.

Integrated Voltage and Power Flow Management Considering the Cost of Opera in Active Distribution Networks

  • Xu, Tao;Guo, Lingxu;Wei, Wei;Wang, Xiaoxue;Wang, Chengshan;Lin, Jun;Li, Tianchu
    • Journal of Electrical Engineering and Technology
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    • v.11 no.2
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    • pp.274-284
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    • 2016
  • The increasing penetration of distributed energy resources on the distribution networks have brought a number of technical impacts where voltage and thermal variations have been identified as the dominant effects. Active network management in distribution networks aims to integrate distributed energy resources with flexible network management so that distributed energy resources are organized to make better use of existing capacity and infrastructure. This paper propose active solutions which aims to solve the voltage and thermal issues in a distributed manner utilizing a collaborative approach. The proposed algorithms have been fully tested on a distribution network with distributed generation units.

Interaction of internal forces of exterior beam-column joints of reinforced concrete frames under seismic action

  • Zhou, Hua;Zhang, Zhisheng
    • Structural Engineering and Mechanics
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    • v.44 no.2
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    • pp.197-217
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    • 2012
  • Detailed analysis of internal forces of exterior beam-column joints of RC frames under seismic action is reported in this paper. A formula is derived for calculating the average joint shear from the column shears, and a formula is proposed to estimate torque in eccentric joints induced by seismic action. Average joint shear stress and strain are defined consistently for exterior joints, which can be used to establish joint shear constitutive relationship. Numerical results of shear, bending moment and torque in joints induced by seismic action are presented for a pair of concentric and eccentric exterior connections extracted from a seismically designed RC frame, and two sections located at the levels of beam bottom and top reinforcement, respectively, are identified as the critical joint sections for evaluating seismic joint behavior. A simplified analysis of the effects of joint shear and torque on the flexural strengths of the critical joint sections is made for the two connections extracted from the frame, and the results indicate that joint shear and torque induced by a strong earthquake may lead to "joint-hinging" mechanism of seismically designed RC frames.

Stable Microbial Community and Specific Beneficial Taxa Associated with Natural Healthy Banana Rhizosphere

  • Fu, Lin;Ou, Yannan;Shen, Zongzhuan;Wang, Beibei;Li, Rong;Shen, Qirong
    • Journal of Microbiology and Biotechnology
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    • v.29 no.10
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    • pp.1624-1628
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    • 2019
  • Banana planting altered microbial communities and induced the enrichment of Fusarium oxysporum in rhizosphere compared with that of forest soil. Diseased plant rhizosphere soil (WR) harbored increased pathogen abundance and showed distinct microbial structures from healthy plant rhizosphere soil (HR). The enriched taxon of Bordetella and key taxon of Chaetomium together with some other taxa showed negative associations with pathogen in HR, indicating their importance in pathogen inhibition. Furthermore, a more stable microbiota was observed in HR than in WR. Taken together, the lower pathogen abundance, specific beneficial microbial taxa and stable microbiota contributed to disease suppression.

Structural configurations and dynamic performances of flexible riser with distributed buoyancy modules based on FEM simulations

  • Chen, Weimin;Guo, Shuangxi;Li, Yilun;Gai, Yuxin;Shen, Yijun
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.13 no.1
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    • pp.650-658
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    • 2021
  • Flexible risers are usually used as conveying systems to bring ocean resources from sea bed up to onshore. Under ocean environments, risers need to bear complex loads and it is crucial to comprehensively examine riser's configurations and to analyze structural dynamic performances under excitation of bottom vehicle motions, to guarantee structural safe operation and required service lives. In this study, considering a saddle-shaped riser, the influences of some important design parameters, including installation position of buoyancy modules, buoyancy ratio and motion of mining vehicle, on riser's configuration and response are carefully examined. Through our FEM simulations, the spatial distributions of structural tensions and curvatures along of riser length, under different configurations, are compared. Then, the impacts of mining vehicle motion on riser dynamic response are discussed, and structural tolerance performance is assessed. The results show that modules installation position and buoyancy ratio have significant impacts on riser configurations. And, an appropriate riser configuration is obtained through comprehensive analysis on the modules positions and buoyancy ratios. Under this proposed configuration, the structural tension and curvature could moderately change with buoyancy modules and bottom-end conditions, in other words, the proposed saddle-shaped riser has a good tolerance performance to various load excitations.

New emerging viral infections in human beings that first appeared in Asia: a summary for the present decade 2001 - 2010

  • Wiwanitkit, Viroj
    • CELLMED
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    • v.1 no.1
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    • pp.3.1-3.4
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    • 2011
  • Emerging infectious diseases are usually a public concern. The presence of new emerging infectious diseases is a topic to be reported on and discussed about in medicine. Several new emerging infectious diseases have occurred within the present decade. In this specific review, the author briefly reviews the important new emerging human viral infections that first appeared in Asia during the present decade, 2001 - 2010.

CONVERGENCE OF THE NONMONOTONE PERRY-SHANNO METHOD FOR UNCONSTRAINED OPTIMIZATION

  • Ou, Yigui;Ma, Wei
    • Journal of applied mathematics & informatics
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    • v.30 no.5_6
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    • pp.971-980
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    • 2012
  • In this paper, a method associating with one new form of nonmonotone linesearch technique is proposed, which can be regarded as a generalization of the Perry-Shanno memoryless quasi-Newton type method. Under some reasonable conditions, the global convergence of the proposed method is proven. Numerical tests show its efficiency.