• Title/Summary/Keyword: HP1

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The Enzyme Inhibitory Activity of Ethanol Extracts Derived from Germinated Rough Rice (Oryza sativar L.) Treated by High Pressure (발아와 고압처리에 따른 벼(Oryza sativar L.) 추출물의 효소저해활성)

  • Kim, Min Young;Lee, Sang Hoon;Jang, Gwi Young;Park, Hye Jin;Li, Meishan;Kim, Shinje;Lee, Youn Ri;Lee, Junsoo;Jeong, Heon Sang
    • Korean Journal of Food Science and Technology
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    • v.46 no.1
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    • pp.44-50
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    • 2014
  • We evaluated the enzyme inhibitory activity of germinated rough rice (Oryza sativar L.) treated by high pressure (30MPa) for 24 h (HP24) and 48 h (HP48). In rice germinated for 1 day, the ${\alpha}$-glucosidase inhibitory activity reached its highest level, 68.32%, at HP48. The ${\alpha}$-amylase inhibitory activity increased from 32.66-57.00% at HP0, to 43.67-74.82% at HP48. On the other hand, the inhibitory activity of angiotensin-converting enzyme increased from 27.98% to 49.42% over the course of the second day of HP48. The inhibitory activity of xanthine oxidase peaked of 67.51% at HP48 and subsequently decreased. Lipase inhibitory activity increased from 24.04-47.91% at HP0, to 29.62-64.63% at HP48. These results provide useful information for the use of germinated rough rice as a functional food material and demonstrate that high-pressure treatment during the germination process efficiently increase enzyme inhibitory activity.

Concentrations of Progesterone and Estradiol in Peripheral Plasma during the Estrous Cycle and after Ovariectomy in Huanghuai Goats of High or Poor Prolificacy

  • Pang, X.S.;Wang, Z.Y.;Zhu, T.G.;Yin, D.Z.;Zhang, Y.L.;Meng, L.;Wang, F.
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.2
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    • pp.188-196
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    • 2010
  • The objective of this study was to characterize the litter sizes in Huanghuai goats with high prolificacy (HP, five or more kids born per litter on at least one occasion), and to compare their peripheral blood concentrations of progesterone and estradiol with those of goats with poor prolificacy (PP, up to three kids born per litter on any occasion). The circulating concentrations of progesterone and estradiol were measured by radioimmunoassay from daily blood samples taken during natural estrus cycles and at 1-5 days after ovariectomy. Estrus was synchronized using two doses of a prostaglandin analog. Litter size for the HP goats increased up to a parity of five and decreased thereafter. The percentage of goats with litter sizes of $\geq$4 from parities 3 to 6 ranged from 44.5% to 58.3%. Although small differences in litter size were obtained for goats of parities three, four and six relative to five, parity five does had the highest mean litter size. Progesterone concentrations began to rise earlier and were higher in the HP than in the PP goats on most days of the luteal phase, but not during the follicular phase of the cycle or after ovariectomy. There was a significant difference between the two groups (p<0.05) in the magnitude of the progesterone plateau. Mean estradiol concentrations in the HP group remained significantly higher than in the PP group (p<0.05) during the estrus cycle. There were two estradiol peaks in the HP goats during the early luteal phase, but only one in the PP group. Measurements of individual corpora lutea (CL) in vitro showed that there was a greater prevalence of small CL (<6 mm in diameter) in the HP group than in the PP group (p<0.05). After ovariectomy, the estradiol level on day 1 was significantly higher than at the nadir during the estrus cycle in both the HP (p<0.01) and PP (p<0.05) goats, while levels decreased by 12.3% and 26.2% respectively compared with the mid-luteal period in HP and PP goats (p<0.05). The overall mean estradiol concentrations in HP goats were lower than in the PP group, but no significant differences were found between groups at 1-5 days after ovariectomy.

Changes in soft tissue chin resulting from premolar extraction and incisor retraction in adult female patients (성인 여성에서 소구치 발치와 전치부 후방 견인에 따른 이부 연조직 변화)

  • Kim, Yang-Hee;Son, Woo-Sung
    • The korean journal of orthodontics
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    • v.31 no.5 s.88
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    • pp.535-548
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    • 2001
  • The purpose of this study was to evaluate changes in soft tissue chin thickness and to investigate correlations between hard and soft tissues measurements after orthodontic treatment conducted by premolars extraction and incisor retraction. The sample consisted of 35 female adults with Angle classification class I or class II division 1 malocclusion. Using lateral cephalometric radiographs taken before and after treatment, hard and soft tissue structures were measured and reproducible six landmark on soft chin tissue were used to locate the various points of soft tissue contour of the chin. The res에ts were as follows : 1. There were signigicant correlations between pretreatment B-B', Pm-Pm' and pretreatment vortical skeletal measurements such as $MP{\perp}HP,\;MP{\perp}PP$, ALFH and between a-a', b-b', Me-Me' and measurements of sym-physeal morphology such as SL, SW, PL. 2. There were significant decreases at B-B', Pm-Pm' and significant increases at a-a', b-b' between pre-and posttreatment mea surements. 3. There were significant correlations among soft tissues changes and hard tissue changes except for changes at B-B' and the range of correlation coefficient was about 0.3-0.4. 4. There were significant differences at ${\Delta}UI-VP,\;LI{\perp}, and B-B' measurements between subgroups divided by posttreatment Pog-Pog' changes. 5. There were significant differences at ${\Delta}overbite,\;NPog{\perp}HP,\;and\;Me-Me'$ measurements between subgroups divided by posttreatment Me-Me' changes.

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The Heterochromatin-1 Phosphorylation Contributes to TPA-Induced AP-1 Expression

  • Choi, Won Jun
    • Biomolecules & Therapeutics
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    • v.22 no.4
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    • pp.308-313
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    • 2014
  • Activator protein-1 (AP-1) is an inducible transcription factor that contributes to the generation of chronic inflammation in response to oxidative and electrophilic stress. Previous studies have demonstrated that the PI3K/Akt1 pathway plays an important role in the transcriptional regulation of AP-1 expression. Although the histone post-translational modifications (PTMs) are assumed to affect the AP-1 transcriptional regulation by the PI3K/Akt pathway, the detailed mechanisms are completely unknown. In the present study, we show that heterochromatin 1 gamma ($HP1{\gamma}$) plays a negative role in TPA-induced c-Jun and c-Fos expression. We show that TPA-induced Akt1 directly phosphorylates $HP1{\gamma}$, abrogates its suppressive function and increases the interaction between histone H3 and 14-3-$3{\varepsilon}$. Collectively, these our data illustrate that the activation of PI3K/Akt pathway may play a permissive role in the recruitment of histone readers or other coactivators on the chromatin, thereby affecting the degree of AP-1 transcription.

Tooth bleaching effect by light activation on the tooth surface and intra-pulpal temperature: an in vitro study (광활성 유무가 치아미백과 치아표면 및 치수 내 온도에 미치는 영향)

  • Shim, Youn-Soo;Woo, Hee-Sun
    • Journal of Korean society of Dental Hygiene
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    • v.14 no.4
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    • pp.585-591
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    • 2014
  • Objectives : The purpose of this study was to investigate of the color change, tooth surface and intra-pulpal temperature of tooth bleaching by light activation Methods : Forty-eight extracted bovine teeth were immersed into a tea solution for 24 hours. The specimens were randomly divided into four groups(n=15):(G1) 15% HP + without light activation, (G2) 15% HP + light activation, (G3) 25% HP + without light activation, (G4) 25% HP + light activation. All specimens were bleached for 15 minutes three times. The spectrophotometer (CM-2600d, Konica Minolta, Osaka, Japan) was used including before bleaching, immediately after bleaching, 1 week, 1 and 3 months after the end of bleaching. The temperature rise were measured in the pulpal chamber and tooth surface with a digital thermocouple thermometer(Termopar Digital Multimeter, Tektronix DMM916, USA). Between the tested time points, the specimens were stored in distilled water. The data were analyzed by ANOVA, t-test and Tukey's post hoc test set at 0.05. Results : There was no significant color change by the use of light after the bleaching treatment(p>0.05). The dental bleaching treatments of teeth with 15% HP and 25% HP did not seem to be more effective when light source was used. There was no difference in color stability between groups within three month(p>0.05). There was an increase in tooth surface and pulp temperature, but it was not sufficient to cause damage to the pulp. Conclusions :The use of light activation has no obvious effective impact on the tooth bleaching effect.

The Clinical Study about the Thermal Temperature Changes on Herbal Acupuncture Therapy (약침시술(藥鍼施術)이 체표온도변화(體表溫度變化)에 미치는 영향(影響))

  • Kim, Byung-ha;Shin, Min-seop;Yook, Tae-han
    • Journal of Acupuncture Research
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    • v.19 no.5
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    • pp.124-135
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    • 2002
  • Objective : This study was done to observe the effects on the thermal changes of herbal acupuncture. There were remarkable local thermal changes between pre and post herbal acupuncture therapy on D.I.T.I. or not. If there are those, we examine how long changes of those were maintained, what is the adequate interval on herbal acupuncture therapy. Methods : D.I.T.I, was used to study the local thermal changes in herbal acupuncture therapy. Determination of this analysis periods are pre and post-therapy(1hour, 1day, 7days later). The study group was divided into six groups that are NS group(No.=20), CF group(No.=22), BU group(No.=23), BUM group(No.=19), HP group(No.=20) and BV group(No.=l9). The herbal acupuncture was injected by 0.2ml divided into 0.05ml at the Fengmen(風門: B12), Feishu(肺兪: B13), Fufen(附分: B41), Pohu(魄戶: B42) 4 points. Then, we checked the thermal changes of their point after performing. Results : The following results were obtained ; 1. In CF groups, significant dermatothermal difference between pre and post therapy was not checked, In BU group that continued until post-therapy 1day, in HP group until 1hour, in BV group until 2days. In BUM, HP and BV group, Most dermatothermal difference was checked at post-therapy 1hour, in BU group at post-therapy 1day. 2. At post-therapy 1 hour, significant dermatothermal different between pre and post therapy was checked among BU group, BUM group, HP group and BV group. At post-therapy 1day and 2days, checked among BU group, BUM group and BV group. At post-therapy 7days, not checked among all groups. The group that highest dermatothermal difference were checked is BV group.

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An Isolation of Crude Saponin from Red-Ginseng Efflux by Diaion HP-20 Resin Adsorption Method (홍삼유출액으로부터 Diaion HP-20 수지 흡착법에 의한 조사포닌의 분리)

  • 곽이성;경종수;김시관;위재준
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.1
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    • pp.1-5
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    • 2001
  • This study was carried out to isolate saponin compounds from red-ginseng efflux, which was produced during the industrial processing of red-ginseng from fresh ginseng. We isolated crude saponin from the efflux extract (moisture content 35.0%) by using Diaion HP-20 adsorption method. Non-saponin fraction, which was adsorbed on Diaion HP-20 resin, was removed by eluating with $H_{2}O$ and 25% spirit. Then crude saponin was eluated with 95% spirit, continuously. Saponin in the eluated fractions was confirmed by TLC analysis. Crude saponin isolated from red ginseng efflux extract contained 12.10% of saponin. whereas those of white ginseng and red-ginseng were 3.30 and 3.39%, respectively. Ginsenoside contents showed the highest contents kin crude saponin from red ginseng efflux extract. Expacilly, the ginsenoside-$Rb_{1}$ and Re showed the highest contents in red-ginseng efflux extract when compared with those of white ginseng and red ginseng crude saponins. And the other ginsenosides except ginsenoside-$Rb_{1}$ and -Re also showed the highest contents in red ginseng efflux extract. However, the ratio of PD saponin (Panaxadiol saponin: $Rb_{1}+Rb_{2}$+Rc+Rd) to PT saponin (panaxatriol: $Re+Rg_{1}$) showed almost the same level when compared with those of ginseng saponin fractions. Ratio of PD/PT from red ginseng efflux extract was 1.99. Ratios of PD/PT from white ginseng and red ginseng were 1.85 and 1.84, respectively. Saponin purity, which was calculated by ratio percent of total ginsenoside to curde saponin content, was 45.90%. In case of white ginseng and red ginseng, the purities were 35.50 and 36.00%, respectively. However, by PHLC analysis, we confirmed that crude saponin isolated from red ginsengs. It suggested that crude saponin isolated from red ginseng ellux also would be useful component as ginseng saponins.

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ERROR ANALYSIS OF THE hp-VERSION UNDER NUMERICAL INTEGRATIONS FOR NON-CONSTANT COEFFICIENTS

  • KIM, IK-SUNG
    • Honam Mathematical Journal
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    • v.27 no.2
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    • pp.317-332
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    • 2005
  • In this paper we consider the hp-version to solve non-constant coefficients elliptic equations on a bounded, convex polygonal domain ${\Omega}$ in $R^2$. A family $G_p=\{I_m\}$ of numerical quadrature rules satisfying certain properties can be used for calculating the integrals. When the numerical quadrature rules $I_m{\in}G_p$ are used for computing the integrals in the stiffness matrix of the variational form we will give its variational form and derive an error estimate of ${\parallel}u-{\widetilde{u}}^h_p{\parallel}_{1,{\Omega}$.

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People Interview - 한국HP 최준근 사장

  • Korea Database Promotion Center
    • Digital Contents
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    • no.10 s.113
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    • pp.39-39
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    • 2002
  • "지난해 5월 8일 본사의 합병계획이 발표됐다. 한국은 5월 22일부터 시작돼 3개월이 시각이 흘렀다. 합병 발표후 각 사의 제품과 테크놀로지의 통합에 초점을 맞췄다. 한국HP와 컴팩코리아가 통합되면서 1400여명이 1조9000억원 매출을 달성하는 조직의 수장을 맡게 된 최준근(50) 사장은 최근 'hp-way'로 유명한 사내게시판(무기명 견해 작성)을 찾는 횟수가 일주일에 한번 수준에서 매일로 바뀌었다고 한다. 합병 후 직원들의 심리를 조금이라도 더 파악하기 위해서다. '인사가 만사임을 느낀다'는 최사장을 만나 합병3개월간의 얘기를 들어보았다.

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