• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.3A
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• pp.318-323
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• 2004

In this paper, we present a reducing power consumption of a scheduling for reuse module selection under the time constraint. Traditional high-level synthesis do not allow reuse of complex, realistic datapath component during the task of scheduling. On the other hand, the proposed scheduling of reducing power consumption is able to approach a productivity of the design the low power to reuse which given a library of user-defined datapath component and to share of resource sharing on the switching activity in a shared resource. Also, we are obtainable the optimal the scheduling result in experimental results of our approach various HLS benchmark environment using chaining and multi-cycling in the scheduling techniques.

• Journal of Preventive Medicine and Public Health
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• v.25 no.3 s.39
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• pp.269-286
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• 1992

The purpose of this study is to investigate the present state of worker's recognition and attitude about hazard materials and occupational disease in his workplace. In general worker's view of hazard materials and occupational disease that sis recognition and attitude is related to worker's health behavior for preventing occupational disease and improving his health status. The study subject is composed of workers in the asbestos related industry for example brake lining manufacturing industry, asbestos fiber manufacturing industry, and asbestos slate manufacturing industry. The result of the study are follows : 1. The most of workers in the asbestos related industry have taken health education and safety education, and the more than half of workers recognized the usefulness of preventive device, and ventilatory device in workplace. 2. About 70% of workers have always taken the preventive device. 3. About 80% of workers have recognized occupational disease in the asbestos related industry, and about 64% of workers have recognized that hls workplace have harmful effect on his health. 4. Recognition about the usefulness of ventilatory device in work place has not related with any variables. But recognition about the usefulness of repiratory protector has related with recognition of hazard materials in his workplace, for example asbestos. 5. Attitude about severity and susceptability of occupational disease in the asbestos related industry have related with knowledge about hazard materials and occupational disease.

• Journal of Information Processing Systems
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• v.19 no.3
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• pp.385-393
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• 2023

Since the proportion of elderly citizens is increasing every year, the social interest is increasing for the health and the safety of the elderly. The nursing home is continually being created to care for more elderly people. However, the quality of service is not enough due to the lack of elderly caregivers. Elderly care and management services are being studied to replace the shortage of caregivers. Existing research for the implementation of an automatic care system has a high initial system cost. Furthermore, it lacks the ability to store and manage large amounts of data. In this paper, we propose a system that manages a large amount of data continuously generated through CCTV and provides a streaming service with a high level of quality-of-service (QoS) to users with collected video. Through the proposed system, it is possible to record and manage the behavioral information of the elderly occurring in the nursing home together with the video. In addition, according to the user's request, it has built a service that streams the video and behavioral information according to the date and time in real-time.

• IEMEK Journal of Embedded Systems and Applications
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• v.13 no.1
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• pp.17-24
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• 2018

Military camera equipment has a problem that observability is inferior due to various shaking factors. In this paper, we propose an image stabilization algorithm considering performance and execution time to solve this problem and implemented it in Zynq SoC. We stabilized both the simple shaking in the fixed observation position and the sudden shaking in the moving observation position. The feature of the input image is extracted by the Sobel edge algorithm, the subblock with the large edge data is selected, and the motion vector, which is the compensation reference, is calculated through template matching using the 3-step search algorithm of the region of interest. In addition, the proposed algorithm can distinguish the shaking caused by the simple shaking and the movement by using the Kalman filter, and the stabilized image can be obtained by minimizing the loss of image information. To demonstrate the effectiveness of the proposed algorithm, experiments on various images were performed. In comparison, PSNR is improved in the range of 2.6725~3.1629 (dB) and image loss is reduced from 41% to 15%. On the other hand, we implemented the hardware-software integrated design using HLS of Xilinx SDSoC tool and confirmed that it operates at 32 fps on the Zynq board, and realized SoC that operates with real-time processing.

• Journal of Microbiology and Biotechnology
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• v.16 no.5
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• pp.695-703
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• 2006

The dissolved oxygen level of any cell culture environment has a critical effect on cellular metabolism. Specifically, hypoxia condition decreases cell viability and recombinant protein productivity. In this work, to develop CHO cells producing recombinant protein with high productivity, mammalian expression vectors containing a human tissue-type plasminogen activator (t-PA) gene with hypoxia response element (HRE) were constructed and stably transfected into CHO cells. CHO/2HRE-t-PA cells produced 2-folds higher recombinant t-PA production than CHO/t-PA cells in a $Ba^{2+}-alginate$ immobilized culture, and 16.8-folds in a repeated batch culture. In a non-aerated batch culture of suspension-adapted cells, t-PA productivity of CHO/2HRE/t-PA cells was 4.2-folds higher than that of CHO/t-PA cells. Our results indicate that HRE is a useful tool for the enhancement of protein productivity in mammalian cell cultures.

• Journal of Computing Science and Engineering
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• v.12 no.1
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• pp.24-35
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• 2018

Deep convolutional neural network (DCNN) is an advanced technology in image recognition. Because of extreme computing resource requirements, DCNN implementation with software alone cannot achieve real-time requirement. Therefore, the need to implement DCNN accelerator hardware is increasing. In this paper, we present a field programmable gate array (FPGA)-based hardware accelerator design of DCNN targeting handwritten Hangul character recognition application. Also, we present design optimization techniques in SDAccel environments for searching the optimal FPGA design space. The techniques we used include memory access optimization and computing unit parallelism, and data conversion. We achieved about 11.19 ms recognition time per character with Xilinx FPGA accelerator. Our design optimization was performed with Xilinx HLS and SDAccel environment targeting Kintex XCKU115 FPGA from Xilinx. Our design outperforms CPU in terms of energy efficiency (the number of samples per unit energy) by 5.88 times, and GPGPU in terms of energy efficiency by 5 times. We expect the research results will be an alternative to GPGPU solution for real-time applications, especially in data centers or server farms where energy consumption is a critical problem.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5825-5828
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• 2014

Background: Lymphomas represent the fifth most frequent cancer in Lebanon. However, little is known concerning epidemiologic characteristics and distribution of lymphoid neoplasms according to the 2008 WHO classification. Materials and Methods: We conducted a retrospective study of lymphoma cases diagnosed from 2008 till 2012 at $H\hat{o}tel$-Dieu de France University Hospital. Results: A total of 502 new cases of lymphoma were diagnosed at our institution during a five year period: 119 cases (24%) were Hodgkin lymphomas (HL) and 383 cases (76%) were non-Hodgkin lymphomas (NHL). HLs were equally distributed in both sexes with a mean age at diagnosis of 30 years. Among NHL, 87% (332 cases) were B cell lymphomas, 9% (34 cases) were T cell lymphomas and 4%(17 cases) were classified as precursor lymphoid neoplasms. Among B cell lymphomas, 44% (147 cases) were diffuse large B cell lymphomas (DLBCL), 20% (65 cases) follicular lymphomas and 8% (27 cases) mantle cell lymphomas. DLBCL were equally distributed in both sexes with a mean age of 58 years. Follicular lymphomas were characterized by a male predominance (57%) and a mean age of 60 years. Mantle cell lymphomas showed a pronounced male predominance (85%) with a mean age of 60 years in men and 70 years in women. Some 72% of patients having T cell lymphomas were men, with a mean age of 57 years in men and 45 years in women, while 65% of patients having precursor lymphoid neoplasms were women with a mean age of 22 years in women and 30 years in men. Conclusions: The lymphoma subtype distribution in Lebanon is unique when compared to other countries from around the world. In fact, Hodgkin and follicular lymphomas are more frequent than in most Far Eastern, European and American countries, while T-cell lymphomas and DLBCL are less frequent.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.3
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• pp.38-48
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• 2017

ISO 9001 Quality Management Systems-Requirements has been revised in 2015. It has been updated four times since its publication in 1987. It is the most widely used International Standard in the world. There are over one million companies and organizations in over 170 countries certified to ISO 9001 from an ISO survey. Organizations are supposed to be certified to this new version by late 2018. The key changes in ISO 9001:2015 are to establish a High Level Structure (HLS) and focus on Risk-Based Thinking (RBT). Risk-Based Thinking means the process approach to decide how risk is addressed in establishing the processes to improve process outputs and prevent undesirable results. It pursues process planning and controls based on risks so that organizations can improve the effectiveness of the quality management system. It maintains and manages a Quality Management System that inherently addresses risks and meets objectives. In this article we firstly attempt to explain how to understand the fundamental concept of Risk-Based Thinking which is a systematic approach to consider risks rather than treating prevention as a separate component of a Quality Management System. We comment on the detailed requirements that contain risks in ISO 9001:2015 clauses. We also summarize recent advances on the risk assessment and management in line with ISO 31000:2009 Risk Management-Principles and Guidelines. We finally propose the practical risk management procedures for implementing ISO 9001:2015 with an emphasis on RBT. This article would contribute to help quality managers and practitioners convert to ISO 9001:2015.

• International Journal of Oral Biology
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• v.30 no.3
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• pp.85-90
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• 2005

Homeostatic pH is very important for various cellular processes, including metabolism, survival, and death. An imbalanced-pH might induce cellular acidosis, which is involved in many abnormal events such as apoptosis and malignancy. One of several factors contributing to the onset of metabolic acidosis is the production of lactate and protons by lactate dehydrogenase (LDH) in anaerobic glycolysis. LDH is an important enzyme that catalyzes the reversible conversion of pyruvate to lactate. This study sought to examine whether decreases in extracellular pH induce apoptosis of CHO cells, and to elucidate the role of mitogen-activated protein kinases (MAPKs) in acidification-induced apoptosis. To test apoptotic signaling by acidification we used CHO dhfr cells that were sensitive to acidification, and CHO/anti-LDH cells that are resistant to acidification-induced apoptosis and have reduced LDH activity by stable LDH antisense mRNA expression. In the present study, cellular lactic acid-induced acidification and the role of MAPKs signaling in acidification-induced apoptosis were investigated. Acidification, which is caused by $HCO{_3}^-$-free conditions, induced apoptosis and MAPKs (ERK, JNK, and p38) activation. However, MAPKs were slightly activated in acidic conditions in the CHO/anti-LDH cells, indicating that lactic acid-induced acidification induces activation of MAPKs. Treatment with a p38 inhibitor, PD169316, increased acidification-induced apoptosis but apoptosis was not affected by inhibitors for ERK (U0126) or JNK (SP600125). Thus, these data support the hypothesis that activation of the p38 MAPK during acidification-induced apoptosis contributes to cell survival.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.41 no.4
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• pp.70-80
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• 2018

The International Organization for Standardization (ISO) published ISO 9001 Quality Management System (QMS)-Requirements in 1987 and has revised four times since then. ISO 9001:2015 is the latest edition. This latest edition has two most noticeable changes. The first major change of new edition focuses on performance with an emphasis on Risk-Based Thinking (RBT) to enhance the process approach. The new edition consists of ten clauses whose first three clauses are largely same as older edition but risks are clearly stated and stressed in last seven clauses, emphasizing on Plan-Do-Check-Act cycle at all levels in the organization. The second major change is that the new edition has the same overall structure as other ISO management system standards known as High Level Structure (HLS) with Annex SL. The companies obtained the certificate of new ISO 9001:2015 QMS by September 15, 2018 in order to maintain as an ISO QMS registered firm. In this article we collected transition audit data from more than 100 companies that registered ISO 9001:2015 QMS for recent three years. We performed a statistical analysis to disclose the relationships between the characteristics of companies and the minor nonconformities found in ISO 9001:2015 requirements during transition audit processes. We also aim to interpret the findings and deduce the implications of the statistical results.