• 한국식품영양과학회지
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• 제38권1호
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• pp.32-38
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• 2009

민간요법 중에서 비만 치료에 사용되는 4종의 식물인 지유, 옥발, 적하수오 및 삼백초를 동량으로 혼합하여 10배의 물을 사용하여 가열추출 후 감압농축 하여 HEM을 조제하였고, 이렇게 조제된 HEM을 사용하여 $0{\sim}100{\mu}g$/mL 농도로 3T3-L1의 지방축적 억제율을 측정한 결과 농도가 증가함에 따라 유의적으로 증가하였으며, 동일 농도에서 세포독성은 없었다. 또한 지방 축적에 관여하는 효소인 GPDH의 활성을 억제함으로써 세포내 지방이 축적되는 것을 억제하였다. 5주간의 동물실험 결과 대조군과 비교하여 HEM1과 HEM2군 모두 체중 변화와 식이효율이 줄어드는 것으로 나타났으며, 혈액 분석에서 HEM군은 혈중 중성지방과 총콜레스테롤에 효과를 보이지 않았다. 해부학적인 측면에서 부고환 및 신장 주위의 지방무게와 간 무게 또한 낮았다. 이러한 결과를 통해, 본 실험에서 사용한 생약복합물은 항비만 소재로써 체지방 축적억제에 효과성이 있음을 확인하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제42권
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• pp.22.1-22.6
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• 2020

Introduction: Facial fractures (FFs) occur after high- and low-energy trauma; differences in associated injuries and outcomes have not been well articulated. Objective: To compare the epidemiology, management, and outcomes of patients suffering FFs from high-energy and low-energy mechanisms. Methods: We conducted a 6-year retrospective local trauma registry analysis of adults aged 18-55 years old that suffered a FF treated at the Santa Barbara Cottage Hospital. Fracture patterns, concomitant injuries, procedures, and outcomes were compared between patients that suffered a high-energy mechanism (HEM: motor vehicle crash, bicycle crash, auto versus pedestrian, falls from height > 20 feet) and those that suffered a low-energy mechanism (LEM: assault, ground-level falls) of injury. Results: FFs occurred in 123 patients, 25 from an HEM and 98 from an LEM. Rates of Le Fort (HEM 12% vs. LEM 3%, P = 0.10), mandible (HEM 20% vs. LEM 38%, P = 0.11), midface (HEM 84% vs. LEM 67%, P = 0.14), and upper face (HEM 24% vs. LEM 13%, P = 0.217) fractures did not significantly differ between the HEM and LEM groups, nor did facial operative rates (HEM 28% vs. LEM 40%, P = 0.36). FFs after an HEM event were associated with increased Injury Severity Scores (HEM 16.8 vs. LEM 7.5, P <0.001), ICU admittance (HEM 60% vs. LEM 13.3%, P <0.001), intracranial hemorrhage (ICH) (HEM 52% vs. LEM 15%, P <0.001), cervical spine fractures (HEM 12% vs. LEM 0%, P = 0.008), truncal/lower extremity injuries (HEM 60% vs. LEM 6%, P <0.001), neurosurgical procedures for the management of ICH (HEM 54% vs. LEM 36%, P = 0.003), and decreased Glasgow Coma Score on arrival (HEM 11.7 vs. LEM 14.2, P <0.001). Conclusion: FFs after HEM events were associated with severe and multifocal injuries. FFs after LEM events were associated with ICH, concussions, and cervical spine fractures. Mechanism-based screening strategies will allow for the appropriate detection and management of injuries that occur concomitant to FFs. Type of study: Retrospective cohort study. Level of evidence: Level III.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2012년도 학술발표회
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• pp.983-983
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• 2012

EFDC의 수질모형인 HEM3D는 국내 해양수질모델링에는 적용된 사례가 많지만 담수에 적용된 사례는 거의 없으며, 우리나라 환경부 수질측정항목과 수질 INPUT 자료가 달라서 모델의 적용이 힘들었다. 그러나 HEM3D는 EFDC 수리모델을 연계하는 WASP에 비해 자체 3차원 수리동역학 모델이 있어 셀 개수의 제한이 없고 계산속도 또한 WASP 보다 2~3배 빠른 것으로 알려져 있다. 그러나 현재 우리나라의 수질측정항목은 HEM3D의 수질모의항목과 다소 차이가 있다. 특히 Carbon계열에서 실측수질항목은 BOD, COD인 반면 HEM3D의 모의가능항목은 RPOC, LPOC, DOC, COD로 바로 적용을 하기는 어렵다고 판단하였다. 따라서 환경부 수질자료를 HEM3D에 적용하기위해 문헌자료를 참고한 수질항목간의 분율을 사용하여 필요한 자료를 산출하였고, 환경부 수질자료의 HEM3D적용 결과를 알아보고 현재 자료 사용 시의 문제점과 향후 개선방안을 알아보고자 하였다. HEM3D의 모의 결과 TN, TP 보정에는 큰 문제가 없었으나 $BOD_5$와 세부수질항목의 영향을 많이 받는 조류 등의 항목 보정결과는 성공적이지 못했다. 이것은 분율을 적용해 각 유입지천의 세부항목별 수질 자료를 산출할 때 낙동강 전체 평균을 사용했기 때문에 조류성장에 직접적으로 영향을 받는 세부 항목별 영양염에 대한 실제 값과 산출된 농도 값 사이의 오차가 가장 큰 원인으로 판단된다. 한편 전체 대상지역중 일부구간에 대하여 동일한 수질입력자료를 이용하여 HEM3D와 WASP을 동시 적용하였다. 자료의 변환과정에서의 오차와 입력형태 및 각 모델 변수형태의 차이 등의 한계로 결과값에 차이가 있는 것으로 나타났으며, 본 연구결과 현재 확보된 수질측정망의 수질자료를 이용하여 HEM3D를 구축하는 것은 Carbon 계열과 조류(부영양화)모의에서 문제가 발생할 것으로 판단되며 추가 자료 확보가 필요할 것으로 보인다. 또한 필요한 입력자료가 충분히 확보가 된다면 추가연구결과에서 볼 수 있듯이 미국공변단과 미국 환경부수질모델 모두 동시적용이 가능하다고 판단되며 목적과 편의에 따라 선택적 모의가 가능하다고 판단된다.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2003년도 Proceedings of the international symposium on the fusion technology
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• pp.422-431
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• 2003

Helicopter-borne electromagnetic (HEM) systems were originally developed for the exploration of mineral deposits. The frequency range of a conventional HEM system for mineral exploration, however, is relatively low and so not invariably suitable for its application to the fields of civil engineering because of its poor resolution in the shallower part of the earth. A DIGHEM HEM system was acquired by Nippon Engineering, with the frequencies chosen by the senior author. The five frequencies range from 220 Hz (the lowest) to 137,500 Hz (the highest). These frequencies improve the resolution of materials in the shallower part while maintaining a depth of investigation of greater than 100 m. This paper describes six case histories of geological and geotechnical surveys for civil engineering using HEM. These case histories include HEM surveys for investigating landslide, an alluvial area, root selection of road construction, areas related to dam and tunnel construction, and the simultaneous joint inversion of HEM and CSAMT data for a deep tunnel. These survey results show that HEM has sufficient resolution in both horizontal and vertical directins to contribute significantly to outlining the regional geology and its engineering problems.

• 한국의상디자인학회지
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• 제17권3호
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• pp.159-168
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• 2015

In this study, visual evaluation was wide pants with changes in length of pants and width of hem line of wide pants design to provide data which can enhance wearing image effects at the production of wide pants. According to the length of pants and width of hem line of wide pants, a total of 9 stimulants were chosen. Then, they were evaluated using a seven-point rating scale against 40 fashion students. The data has been analyzed by Factor Analysis, ANOVA, $Scheff{\acute{e}}$'s Test and the MCA method. The results of the study are as follows : 1. According to factor analysis, the components of visual evaluation depending on the length of pants and width of hem line of wide pants were divided into five factors: individuality, body correction, modesty, body length and cute. 2. According to visual evaluation depending on changes in the length of pants, no significant difference was found in all five positions. 3. According to visual evaluation depending on changes in the length of pants and width of hem line of wide pants, 'width of hem line 60, 100' revealed a significant difference in body correction. 'width of hem line 80' revealed a significant difference in body correction and body length. 4. In terms of interactions over changes in the length of pants and width of hem line of wide pants, no interaction effects were found in all five factors. According to multiple classification analysis(MCA) on the factors without interaction effects, length of pants had more effect on visual image in body correction, body length and cute. In other factors, more influence was observed depending on the width of hem line.

• 한국환경농학회지
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• 제21권1호
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• pp.45-49
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• 2002

하수슬러지 중에 존재하는 HEM에 대해 분석하고, 이를 토양에 사용할 때 발생하는 연간 오염부하량에 대해 추정하였다. 전국의 하수처리장에서부터 수집된 하수슬러지 시료 84점에 대해 분석한 HEM의 평균함량은 27.7$\pm$26.5 g/kg이었고, 최소 1.05에서 최대 194 g/kg을 나타내어 분석시료간에 큰 편차를 보였다. 하수처리장이 위치한 도시의 규모에 따라 5단계로 나누었을 때 HEM의 함량은 광역시, 대도시, 중도시, 소도시, 농촌지역에 각각 22.7$\pm$6.7, 33.3$\pm$25.8, 22.0$\pm$8.7, 31.0$\pm$38.8, 27.7$\pm$25.1 g/kg을 나타내었다. 미국 EPA의 하수슬러지 토양시용량 기준을 적용하여 농경지, 산림, 공공용지, 개량용지로 분류하고 각각 7,000, 26,000, 18,000, 74,000 kg/ha (건물량 기준)를 하수슬러지 최대 사용량으로 가정하여 HEM의 연간 오염부하량을 계산하였다. 건물량 기준으로 시용량이 7,000 kg/ha인 농경지의 경우 최대 1,032 kg/ha의 HEM 부하량을 나타내었고, 개량용지 시용기준인 74,000 kg/ha를 적용한 경우 HEM의 연간 오염부하량은 10,908 kg/ha으로 추정되었다. 그 외 산림기준을 적용할 때는 최대 3,832 kg/ha, 공공용지 기준을 적용할 때는 최대 2,653 kg/ha의 연간 오염부하량이 추정되었다.

• 한국의류학회지
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• 제5권2호
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• pp.49-53
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• 1981

This study was carried out to investigate the drapability of polyester double jersey skirt Drapability is an important aesthetic properties of fabric on clothing construction, In this thesis weight, shearing, bending and non-isotropic characteristics of fabric were regarded as important factors of drapability, Especially for drapability of skirt, I investigated hem effect on various length of hem and skirt, The results were as follows, 1. The less the weight of fabric was, the greater drapability appeared. On fabrics, large pliability and modulus of shear have good drapability, 2. On clothing cutting, non-isotropic property affected on drapability of clothes remark-ably. Drapability order of clothes was greatest in bias direction, next in wale, course direction, 3. The shorter the skirt length and closer at hem line were the larger the hem effect influence upon the drapability of skirt was.

• BMB Reports
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• 제43권5호
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• pp.330-336
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• 2010

5-Aminolevulinate (ALA) is well-known as an essential biosynthetic precursor of all tetrapyrrole compounds, which has been suggested to improve plant salt tolerance by exogenous application. In this work, the gene encoding aminolevulinate synthase (ALA-S) in yeast (Saccharomyces cerevisiae Hem1) was introduced into the genome of Arabidopsis controlled by the Arabidopsis thaliana HemA1 gene promoter. All transgenic lines were able to transcribe the YHem1 gene, especially under light condition. The chimeric protein (YHem1-EGFP) was found co-localizing with the mitochondria in onion epidermal cells. The transgenic Arabidopsis plants could synthesize more endogenous ALA with higher levels of metabolites including chlorophyll and heme. When the $T_2$ homozygous seeds were cultured under NaCl stress, their germination and seedling growth were much better than the wild type. Therefore, introduction of ALA-S gene led to higher level of ALA metabolism with more salt tolerance in higher plants.

• Journal of Microbiology and Biotechnology
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• 제23권5호
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• pp.668-673
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• 2013

A recombinant E. coli co-expressing ALA synthase (hemA), NADP-dependent malic enzyme (maeB), and dicarboxylic acid transporter (dctA) was reported to synthesize porphyrin derivatives including iron-containing heme. To enhance the synthesis of bacterial heme, five genes of the porphyrin biosynthetic pathway [pantothenate kinase (coaA), ALA dehydratase (hemB), 1-hydroxymethylbilane synthase (hemC), uroporphyrinogen III synthase (hemD), and uroporphyrinogen III decarboxylase (hemE)] were amplified in the recombinant E. coli co-expressing hemA-maeB-dctA. Pantothenate kinase expression enabled the recombinant E. coli to accumulate intracellular CoA. Intracellular ALA was the most enhanced by uroporphyrinogen III synthase expression, porphobilinogen was the most enhanced by ALA dehydratase expression, uroporphyrin and coproporphyrin were the most enhanced by 1-hydroxymethylbilane synthase expression. The strain co-expressing coaA, hemA, maeB, and dctA produced heme of $0.49{\mu}mol/g$-DCW, which was twice as much from the strain without coaA expression. Further pathway gene amplifications for the porphyrin derivatives are discussed based on the results.

• 한국의상디자인학회지
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• 제14권4호
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• pp.127-137
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• 2012

The purpose of this study is to recognize the differences of visual evaluation by variations in width of hem line and waistline position of the flare pants. The stimuli are 9 samples: One control group, 3 variations of the width of hem line and 3 variations of the waistline position. The data has been obtained from 44 fashion students. The data has been analyzed by Factor Analysis, Anova, Scheffe's Test and the MCA method. The results of the study are as follows: The visual evaluation by the width of hem line and waistline position of flare pants are composed of 5 factors : physical characteristics, elegance, originality, comfort, and stiffness. Among these factors, the physical characteristic is evaluated to be the most important factor. As a v isual evaluation result o f changes in the width o f hern l ine, 8 4 cm in width (the narrowest width) was highly evaluated in physical characteristics, elegance, and originality factors. For the result of changes in the waistline position, high-waisted flare pants were highly effective in physical characteristics, and also evaluated well in elegance, originality and stiffness factors. The flare pants did not show any interaction between the width of hem line and waistline position. The waistline position had more influence on visual evaluation in physical characteristics, originality and comfort factors while elegance and stiffness factors were affected by the width of hem line.