• Journal of Life Science
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• v.23 no.1
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• pp.84-94
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• 2013

The cytotoxicity of coffee-like green tea (CLGT) was determined in a human breast cancer cell line, MCF-7; a human prostate cancer cell clone, PC-3; a human neuroblastoma cell line, SK-N-SH; and a rat cardiomyoblast cell line, H9c2, with reference to green tea leaves (GTL). The CLGT was prepared by roasting the GTL for 60 min at $240^{\circ}C$ in a temperature-controlled frying pan. The CLGT preparation imitated the flavor and taste characteristics of coffee fairly well according to sensory analysis. The CLGT preparation had no adverse cytotoxic effects on the cancer cells or the normal cells compared to GTL. No significant change in the antioxidant activity was seen in the CLGT preparation compared to that of GTL. The amount of total protein, sugar, and phenolic compounds was reduced in the preparation relative to those in GTL, a fact that might explain the coffee-like flavor and/or taste characteristics of the CLGT preparation. These results suggest that CLGT prepared by roasting GTL for 60 min at $240^{\circ}C$ does not show any adverse effects on cancer cells and normal cells compared to GTL. They imply that CLGT could be safe for human consumption.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.39 no.5
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• pp.544-555
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• 2002

The aim of this study is to develop the $^1H$-MRS data postprocessing software for both single-voxel and multi-voxel technique, which plays and important role as a diagnostic tool in clinical field. This software is based on graphical user interface(GUI) under windows operating system of personal computer(PC). In case of single-voxel MRS, both of raw data in time-domain and spectrum data in frequency-domain are simultaneously displayed in a screen. Several functions such as DC correction, zero filling, line broadening, Lorentz-Gauss filtering and phase correction, etc. are included to increase the quality of spectrum data. In case of multi-voxel analysis, spectroscopic image reconstructed by 3-D FFT was displayed as a spectral grid and overlapped over previously obtained T1- or T2-weighted image for the spectra to be spatially registered with the image. The analysis of MRS peaks were performed by obtaining the ratio of peak area. In single-voxel method, statistically processed peak-area ratios of MRS data obtained from normal human brain are presented. Using multi-voxel method, MR spectroscopic image and metabolite image acquired from brain tumor are demonstrated.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.10 no.3
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• pp.219-225
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• 2000

The spinel structured $LiMn_2O_4$was obtained by two consecutive heat treatment on xerogel; the first heat treatment was at $150^{\circ}C$ and the second at $350^{\circ}C$ was obtained by sol-gel process using an aqueous solution of lithium hydroxide and manganese acetate. The synthesized $LiMn_2O_4$ by the sol-gel process showed a discharge capacity of 88~56 mAh/g after 15 cycles in Li/lM $LiClO_4$(in PC)/$LiMn_2O_4$at a current density of 0.25 mA/$\textrm{cm}^2$ and the voltage ranged 3.5 V to 4.3 V. For the second heat treatment above $350^{\circ}C$, $Mn_2O_3$was formed as a by-product during the synthesis of $LiMn_2O_4$. The heat treatment at $500^{\circ}C$, for example, showed a lower discharge capacity 81~47 mAh/g, after the 15 charge/discharge cycles. The lower capacity was due to the increment of $Mn^{3+}$ ion and this phenomenon was in agreement with the Jahn-Teller distortion.

• Journal of Astronomy and Space Sciences
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• v.21 no.4
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• pp.233-242
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• 2004

The $HCO^+$ 1-0 transition line was observed toward the Sgr B2 region in our Galactic center. We found that there exist two large-scale velocity structures of $v_{lsr}\;{\sim}50\;and\;{\sim}100kms^{-1}$, which are thought to interact with each other. A new gas clump 'OF28 Cloud'('Odenwald & Fazio FIR 38' Cloud), showing different chemical and kinematical properties with the Sgr B2(M) cloud, was found in the $50kms^{-1}$ gas component. Toward the core of this component, we derive the $HCO^+$ total column density, $N(HCO^+)=(2-5){\times}10^{14}cm^{-2}$ and the mass $M=1{\times}10^6M_{\odot}$, by estimating its size, ${\sim}15pc$, from the half-power width of this component. We also found that there is a highly turbulent component in this region in the velocity range of about $100kms^{-1}$. The column density of this component is $N(HCO^+)=1{\times}10^{13}cm^{-2}$. The $HCO^+$ in this region may form effectively by the reaction between $C^+$ and OH, which are the elements whose abundances increase rapidly in shocked region.

• Journal of the Korean Chemical Society
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• v.31 no.6
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• pp.542-554
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• 1987

Tetradentate schiff base cobalt(II) complexes; Co(SED), Co(SND) and Co(SOPD) have been prepared, these complexes have react with dry oxygen in DMSO to form oxygen adducts cobalt(III) complexes; $[Co(SED)(DMSO)]_2O_2,\;[Co(SND)(DMSO)]_2O_2$ and $[Co(SOPD)(DMSO)]_2O_2$. It seems to be that the oxygen adducts cobalt(Ⅲ) complexes have heexa coordinated octahedral configration with tetradentate schiff base cobalt (III), DMSO and oxygen, and the mole ratio of oxygen to cobalt(II) complexes are 1 : 2, these complexes have been identified by IR-Spectra, T.G.A., magnetic susceptibilitis and elemental analysis of C.H.N. and Cobalt. The redox reaction process of Co(SED), Co(SND) and Co(SOPD) complexes was investigated by cyclic voltammetry with glassy carbon electrode in 0.1M TEAP-DMSO. The results of redox reaction process of Co(II) / Co(III) and Co(II) / Co(I) for cobalt(SED) and cobalt(SOPD) complexes and Co(II) / Co(III) process for cobalt(SND) complex are reversible process but Co(II) / Co(I) process of Cobalt(SND) complex is irreversible, and oxygen adduct complexes to quasi reversibly with oxygen should be very closed related to the redox potentials of range, $E_{pc}$ = -0.80~-0.89V and $E_{pa}$ = -0.70~-0.76V.

• Journal of Oriental Neuropsychiatry
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• v.9 no.1
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• pp.59-71
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• 1998

The effect of Samyonjihwangtang(SJT) on th level of brain antioxidants was examined in aged rat. Samyongjihwangtang(SJT) is assed Cervi Pantiri-chum Cornu, Ginseng Radix to Yukmijihwangtang. The experimental groups were divided into three groups and treated as follows ; normal group(NC), Vt.E administrated group(PC), SJT administrated Group(SJT). From the purified microsome of brain tissue, those were measures the amounts of oxidant materials like malonaldehyde(MDA) and H_2O_2, then activities of antioxidants enxymes like Superoxide dismutase, Catalase, NADPH-cytochrome P-450 reductase.The results were as follows;1. In TBA reaction to measure the amount of MDA, oxidant material of brain tissue of aged rat, both treated groups showed significant decrease.2. In the formation of Hydrogen peroxide, the treated group(SJT) showed a little decrease.3. The activity of Superoxide dismutase was increased significantly in both treated groups than normal group.4. the activity of Catalase was increased significantly in both treated groups than normal group. 5. The activity of NADPH-cytochrome P-450 reductase in the treated group(SJT) showed a little increase.According to the above results, it is suggested that Samyongjihwangtag(SJT) has some antioxidant effects on the tissue of brain.

• Journal of the Ergonomics Society of Korea
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• v.28 no.2
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• pp.57-67
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• 2009

This study proposed a practical metaphor development process that consisted of three steps: 1) identifying major functions, 2) developing metaphor candidates, and 3) evaluating appropriateness of the candidates. In the first step, a total of 27 functions might be implemented in a driver information system (DIS) in the near future. Then, three metaphor candidates were selected from existing metaphors, which were reported to be more practical than others by previous studies. Finally, the candidates were evaluated on their appropriateness for driver information systems by using a quick and simple survey. As a result, two metaphors (a PC and a secretary) were identified as the most appropriate ones. The two metaphors can be used to design a variety of interfaces and interactions for driver information systems. In addition, the development process proposed in this study could be applied to developing metaphors for emerging devices with a variety of functions (e.g. PMPs, MP3s, and electronic dictionaries) as well as driver information systems.

• BMB Reports
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• v.34 no.5
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• pp.457-462
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• 2001

Using the monomolecular film technique, we compared the interfacial properties of Staphylococcus simulans lipase (SSL) and Staphylococcus aureus lipase (SAL). These two enzymes act specifically on glycerides without any detectable phospholipase activity when using various phospholipids. Our results show that the maximum rate of racemic dicaprin (rac-dicaprin) hydrolysis was displayed at pH 8.5, or 6.5 with Staphylococcus simulans lipase or Staphylococcus aureus lipase, respectively The two enzymes interact strongly with egg-phosphatidyl choline (egg-PC) monomolecular films, evidenced by a critical surface pressure value of around $23\;mN{\cdot}m^{-1}$. In contrast to pancreatic lipases, $\beta$-lactoglobulin, a tensioactive protein, failed to inhibit Staphylococcus simulans lipase and Staphylococcus aureus lipase. A kinetic study on the surface pressure dependency, stereoselectivity, and regioselectivity of Staphylococcus simulans lipase and Staphylococcus aureus lipase was performed using optically pure stereoisomers of diglycerides (1,2-sn-dicaprin and 2,3-sn-dicaprin) and a prochiral isomer (1,3-sn-dicaprin) that were spread as monomolecular films at the air-water interface. Both staphylococcal lipases acted preferentially on distal carboxylic ester groups of the diglyceride isomer (1,3-sn-dicaprin). Furthermore, Staphylococcus simulans lipase was found to be markedly stereoselective for the sn-3 position of the 2,3-sn-dicaprin isomer.

• Bulletin of the Society of Naval Architects of Korea
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• v.30 no.2
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• pp.44-52
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• 1993

선박에 있어서 철의장품은 종류와 수량이 다양하고 형상이 불규칙하여 대부분의 사업장에서 설계 전산화가 이루어지지 못하고 있는 실정이다. 의장설계실에서는 이를 전산화하기 위하여 먼저 철의장품의 표준을 제정 및 극대화하고 설계작업절차와 물량의 흐름을 전산과 연계하여 체계화 및 표준화하였다. 또한 선박의 전구역에 설치되는 철의장품들을 관련 양식과 함께 국제표준을 근거로 BASICA CADDS, SURFACE DESING, SDDP(structural Design ＆ Detailing Package) SOFTWARE를 이용하여 2차원(2-dimension) 및 3차원(3-dimension) 데이터베이스(database)화 하였으며 이를 POP-UP MENU를 이용, 쉽게 선택함으로써 모델링(modeling) 작업시수를 대폭 감소 시켰으며, 그래픽(graphic)에서 추출한 의장품의 데이터(data)를 의장품의 표준정보 FILE과 연계하여 라벨(LABEL) 및 치수(DIMENSION)를 기입하여 배치도를 추출하고 의장품의 제작, 설치, 계산 및 관리에 소요되는 설치도, 제작도 및 관련 보고서인 BOM(bill of material), PML(pallet material list), 의장제작품 LIST, COG(center of gravity), 관리점 등을 자동추출 및 관리전산망(PC-lan)과 연계할 수 있는 DECOM(철의장 전산설계 전용 package)을 89년에 개 발하여 의장설계에 적용하여 왔으며 ORACLE사의 RDBMS(relational database management system)를 도입하여 이를 보완하므로써 정보의 일관화 및 공유화가 가능하게 되었다. 그 결과 설계 M/H절감, 생산성 향상, 자재 및 관련 정보 전달에 혁신적인 변화 향상을 가져오게 되었다.

• Korean Journal of Environmental Agriculture
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• v.14 no.3
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• pp.263-271
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• 1995

Chemical assessment of soil pollution with heavy metals was made by analyzing the changes in pH, ionic strength, cationic concentration and chemical species in the soil solution. Saturated pastes of the unpolluted soils were made by adding solutions containing Cu or Cd and the final Cu or Cd concentrations were in the range of 0 to 400 mg/kg. After equilibrating for 24 hours at $25^{\circ}C$, the soil solution was extracted from the saturated pastes by the vacuum extraction method and analyzed for pH, electrical conductivity, Cu, Cd, cations and inorganic ligands. Chemical species in soil solution were calculated by the GEOCHEM-PC program employing the input variables of pH, ionic strength(${\mu}$), molar concentrations of cations and ligands. Increasing Cu or Cd additions lowered pH of the soil solution but increased concentrations of Ca, Mg and K resulting in increases of ${\mu}$ of the soil solution. Effects of Cu on lowering pH and increasing ${\mu}$ were greater than those of Cd. Concentrations of Cu or Cd in soil solution were relatively very low as compared to those of additions, but increased linearly with increasing additions representing that concentrations of Cu were higher than those of Cd. At 400 mg/kg additions, concentrations of Cu were in the range of 0.51 to 11.70 mg/L but those of Cd were 34.4 to 88.5 mg/L. Major species of Ca, Mg and K were free ions and these species were equivalent to greater than 95 molar % of the existing respective molar concentrations. These cationic species were not changed by Cu or Cd additions. Major species of Cu in lower pH soils such as SiCL and SL were free $Cu^{2+}$ (>95 molar %), but those in LS having a higher pH were free $Cu^{2-}$ and Cu-hydroxide complex. At 100 mg Cu/kg treatment, $Cu^{2+}$ and Cu-hydroxide complex were equivalent to 73 and 22.4 molar %, respectively. These respective percentages were decreased and increased correspondingly with increasing Cu treatments. Major species of Cd in soil solution were free $Cd^{2+}$ and Cd-chloride complex, representing 79 to 85 molar % for $Cd^{2+}$ and 13 to 20% for Cd-chloride complex at 10 mg Cd/kg treatment. With increasing Cd additions to 400 mg/kg, $Cd^{2+}$ species decreased to $40{\sim}47%$ but Cd-chloride complexes increased to $53{\sim}60$ molar %. These results demonstrated that soil contamination with heavy metals caused an adverse effect on the plant nutritional aspects of soil solution by lowering pH, increasing cations temporarily, and increasing free metal concentrations and species enough to be phytotoxic.