• Title/Summary/Keyword: H2Pc

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A Usability Evaluation of Adaptive Split, Adaptive Style, and Adaptable Menus for Desktop PCs (데스크탑 PC를 위한 적응형 메뉴의 사용성 비교 평가)

  • Park, Jung-chul;Han, Sung-H.;Park, Yong-S.;Cho, Young-Seok
    • 한국HCI학회:학술대회논문집
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    • 2006.02a
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    • pp.419-424
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    • 2006
  • 본 연구는 데스크탑 PC 환경에서 사용될 수 있는 다양한 적응형 메뉴 인터페이스의 사용성을 평가한다. 선택 빈도에 따라 자동으로 변화하는 2가지 방식의 Adaptive menu와 사용자가 메뉴 내에서 원하는 항목의 위치를 직접 변경하는 Adaptable menu의 사용성을 일반적으로 많이 이용되는 Traditional menu와 비교하기 위해 사용자를 동원한 평가 실험을 수행하였다. Adaptive menu에는 선택 빈도가 높은 메뉴 항목이 메뉴의 상단으로 이동하는 Adaptive split menu와 자주 선택되는 항목이 굵은 글씨로 표현되는 Adaptive style menu가 포함된다. 각 방식의 적응형 메뉴가 자주 선택되는 메뉴 항목의 변화에 따라 얼마나 민감하게 영향을 받는지 비교하기 위해, 두 개의 각기 다른 선택 빈도 분포가 이용되었다. 각 실험 조건 별로 사용자가 메뉴 항목을 선택하는 데 걸린 시간과 오류 회수를 측정하였으며, 피실험자로 하여금 시인성, 효율성, 전반적 선호도 등의 주관적인 만족도를 평가하도록 하였다. 각각의 종속 변수들은 분산 분석(ANOVA), Chi-square test, Friedman test 등의 기법을 이용해 분석되었다. 분석 결과, Adaptable menu가 다른 방식의 메뉴들에 비해 수행도와 만족도 모두 높은 것으로 나타났으며, Adaptive split menu는 상대적으로 현실적인 조건 하에서 큰 효용을 갖지 못하는 것으로 나타났다. Adaptive style menu는 수행도 측면에서는 일반적인 메뉴와 큰 차이가 없었지만, 자주 선택되는 항목을 쉽게 파악할 수 있게 해 주고, 선택 빈도의 변화에도 민감하지 않기 때문에 사용자들에게 선호되는 것으로 나타났다. 본 연구의 결과는 데스크탑 PC의 적응형 메뉴 설계에 대한 이용될 수 있으며, 추후 휴대용 정보기기의 적응형 메뉴에 대한 사용성 연구의 기초 자료로도 활용될 수 있을 것으로 기대된다.

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Molecular Mechanism Underlying Hesperetin-induced Apoptosis by in silico Analysis and in Prostate Cancer PC-3 Cells

  • Sambantham, Shanmugam;Radha, Mahendran;Paramasivam, Arumugam;Anandan, Balakrishnan;Malathi, Ragunathan;Chandra, Samuel Rajkumar;Jayaraman, Gopalswamy
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4347-4352
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    • 2013
  • Aim: To investigate the molecular mechanisms underlying triggering of apoptosis by hesperetin using in silico and in vitro methods. Methods: The mechanism of binding of hesperetin with NF-${\kappa}B$ and other apoptotic proteins like BAX, BAD, $BCL_2$ and $BCL_{XL}$ was analysed in silico using Schrodinger suite 2009. In vitro studies were also carried out to evaluate the potency of hesperetin in inducing apoptosis using the human prostate cancer PC-3 cell line. Results: Hesperetin was found to exhibit high-affinity binding resulting from greater intermolecular forces between the ligand and its receptor NF-${\kappa}B$ (-7.48 Glide score). In vitro analysis using MTT assay confirmed that hesperetin reduced cell proliferation ($IC_{50}$ values of 90 and $40{\mu}M$ at 24 and 48h respectively) in PC-3 cells. Hesperetin also downregulated expression of the anti-apoptotic gene $BCL_{XL}$ at both mRNA and protein levels and increased the expression of pro-apoptotic genes like BAD at mRNA level and BAX at mRNA as well as protein levels. Conclusion: The results suggest that hesperetin can induce apoptosis by inhibiting NF-${\kappa}B$.

A Development and Design of Embedded Linux System (Embedded Linux 시스템 설계 및 구현에 관한 연구)

  • 유임종;고성찬
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2003.10a
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    • pp.129-132
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    • 2003
  • In this paper, which sees the Strong-ARM SA1110 it used the main CPU and RTP in VoIP system. It will be able to apply the information communication field it embodied. It used the Tynux_box2 with the hardware side and it composed a VOIP system. And it used the RTP which is a real-time protocol in software control portion. The development environment of the paper that used the Target board and a Linux PC for connection used the RS-232C, USB connection, Ethernet LAN. The VoIP the environment for a communication used the wave file in the substitution which changes analog signal with the digital signal. And For the communication of the both sides it used the socket. This paper explained the fact that against a general technique from the operation of VoIP system. Using the Embedded linux development board which explained an operational process of the RTP protocol.

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Development of Transgenic NT Embryos Using Bovine Fetal Fibroblasts Transfected with hFSH Gene (hFSH 유전자가 도입된 소 태아섬유아세포를 이용한 형질 전환 복제 수정란의 발달)

  • Yang B.C.;Im G.S.;Kim D.H.;Min K.S.;Yoon D.H.;Park H.S.;Kim S.W.;Hwang I.S.;Seo J.S.;Seong H.H.;Yang B.S.
    • Journal of Embryo Transfer
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    • v.21 no.1
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    • pp.13-20
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    • 2006
  • The purpose of this study was to develope the transgenic cattle expressing hFSH into the urine using the nuclear transfer. To produce the interest gene in urine, the specific vector was ligated with hFSH gene undo. maUII promoter. The fetal fibroblast cells (KbFF) were isolated from a 45-day male fetus. The hFSH gene was co-transfected with pcDNA3 (neo) vector to KbFF cells by electroporation. The gene-transfected cells were cultured with G-418 selection medium for 2 weeks. Selected colonies were confirmed by PCR. For nuclear transfer, enucleated bovine oocytes were transferred with hFSH transfected or nontransfected fetal fibroblasts. The cleavage and blastocyst formation rates were significantly lower (p<0.05) in cloned embryos transfected with hFSH gene (68.7% and 15.7%) than in those non-transfected (67.6% and 24.5 %), respectively. Apoptosis analysis showed no difference between hFSH transfected and non-transfected blastocysts (p>0.05). The blastocysts were transfected to 77 (control 24, hFSH 53) recipient cows. Two calves were born (1.9%) following transfer with NT embryos transfected with hFSH gene, but they were confirmed not to be transgenic calves. This result shows that the hFSH colonies were mixed with transfected and non transfected cells. Further research will be needed for selection and establishment of gene transfected cells.

External morphology and vegetation of Megaleranthis saniculifolia populations in four different habitats (모데미풀의 자생지별 외부형태 및 식생)

  • 유기억;이우철;오영주
    • Korean Journal of Plant Resources
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    • v.12 no.4
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    • pp.312-323
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    • 1999
  • External morphology, principal component analysis, cluster analysis, and vegetation were investigated to understand the taxonomic relationships and native environmental characters of Megaleranthis saniculifolia populations in four different habitats. Morphological characters such as calyx length and width, calyx index, presence or absence of serrate in calyx lobe, length of peduncle, branch of peduncle and fruit characters were useful for the identification of four different habitats. But, characters of plant height, bract and seed in four habitats were similar. The results obtained based on the principal component(PC) analysis of treated 96 OTU were divided into two groups by PC 1, 2, 3, and the sums of contributions for the total variance were 66.79%(PC1 31.3%, PC2 20.7%, PC3 15.8%, respectively), and only Mt. Taeki population was distinctly different from populations of other three habitats. In cluster analysis based on average linkage cluster analysis and Ward's method, there were similarities in the composition of clustered taxa, and each populations were not identified. Importance value by relative coverage and frequency appeared in M. saniculifolia(50.81%), Aruncus dioicus(12.64%), Corydalus turtschanovii(11.62%), Veratrum oxysepalum(11.45%), Anemone koraiensis(8.96%), Meehania urticifolia(8.76%), Filipendula palmata(7.06%), Aconitum pseudo-laeve(5.66%), Pseudostellaria palibiniana(5.45%) and Smilacina japonica(5.25%), respectively. These species were considered to be highly similar with M. saniculifolia. The highest importance value in all investigated sites was M. saniculifolia, but specific composition of high level different from each habitat. Average diversity of species was 1.40, and the highest in Mt. Kwangdeok(1.31), lowest in Mt. Jumbong(1.17). Average soil pH was 5.25 and similar in each habitat. Although the lowest content of K ion, but the highest the EC, water capacity, organic compound, Ca content were found in soil of Mt. Sobaek. Soils in Mt. Kwangdeok had the lowest content of EC, organic compound, Ca. Soils of Mt. Jumbong showed the highest of Mg content, but the lowest of water capacity, $P_2O_5$, and K contents.

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Cu/Si/Cu Ohmic contacts to n-type 4H-SiC (n형 4H-SiC의 Cu/Si/Cu 오옴성 접합)

  • 정경화;조남인;김민철
    • Proceedings of the International Microelectronics And Packaging Society Conference
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    • 2002.11a
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    • pp.73-77
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    • 2002
  • Characteristics of Cu/Si/Cu ohmic contacts to n-type 4H-SiC were investigated systematically. The ohmic contacts were formed by rf sputtering of multi layer Cu/Si/Cu sputtered sequentially. The annealings were peformed With 2-Step using RTP in vacuum ambient. The specific contact resistivity($\rho$c), sheet resistance(Rs), contact resistance(Rc), transfer length(L$_{T}$) were calculated from resistance(R$_{T}$) versus contact spacing(d) measurements obtained from TLM(transmission line method) structure. Best results were obtained for a sample annealed at vacuum as $\rho$c = 1.0x10$^{-6}$ $\Omega$$\textrm{cm}^2$, Rc = 2$\Omega$ and L$_{T}$ = 1${\mu}{\textrm}{m}$. The physical properties of contacts were examined using XRO and AES. The results showed that copper silicide was formed on SiC and Cu was migrated into SiC.o SiC.

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The Effects of Media on the Intramolecular Photocycloaddition of 3-(3-Butenyl)cyclohex-2-enone

  • 노태희;최균선;박종욱
    • Bulletin of the Korean Chemical Society
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    • v.19 no.5
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    • pp.501-503
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    • 1998
  • In this work, we applied the 1D $11^B$ nutation NMR method for the analysis of the local structural environments in powdered borosilicates $(SiO_2-B_2O_3)$. Spin dynamics during a rf irradiation for spin I=3/2 was analytically calculated with a density ma trix formalism. Spectral simulation programs were written in MATLAB on a PC. Two borosilicates prepared by the sol-gel process at different stabilization temperature were used for the 1D $11^B$ nutation NMR experiment. The $11^B$ NMR parameters, quadrupole coupling constants $(e^2qQ/h)$ and asymmetry parameters (η), for each borosilicate were extracted from the nonlinear least-squares fitting. The effects of heat treatments on the local structures of boron sites in borosilicates were discussed.

Application of Principal Component Analysis to Shelf-Life Determination of Processed Food (주성분분석을 이용한 식품의 저장중 품질변화 평가)

  • Kim, Jung-Hoan;Yoon, Sang-Gi;Choi, Jun-Bong;Kim, Jae-Cherl;Kong, Un-Young
    • Korean Journal of Food Science and Technology
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    • v.27 no.5
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    • pp.703-707
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    • 1995
  • Shelf-life dating of cooked and heat sterilized food was carried out with the use of principal component analysis (PCA). Changes in color, pH, acidity and sensory properties were measured and analyzed during storage at 20, 30 and $40^{\circ}C$. Acceptability of sample was decreased during storage, shelf-life of sample was determined 1.5, 3 and 3 months at 20, 30 and $40^{\circ}C$, respectively. Application of PCA to quality evaluation, principal component (PC) 1 dominated 49.6% of total variation and PC 2 expressed 28.8%. The rate of change of PC 1 to storage time was 1.3 with increasing temperature of $10^{\circ}C$, and close to shelf-life determined by accepability at 20 and $40^{\circ}C$. Therefore, PCA was applicable to evaluate the quality, predict the shelf-life and investigate the quality parameter of food during storage.

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Recovery of Nitric acid and Copper from Plating Waste of Automobile Wheel (자동차 휠 도금박리폐액으로부터 질산 및 구리의 회수)

  • Ha, Yonghwang;Gang, Ryun-Ji;Son, Seong-Ho;Lee, Wonsik;Ahn, Jong-Gwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.11
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    • pp.6015-6022
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    • 2013
  • It has been known that there are large amount of nitric acid and valuable metals, copper in the plating waste solution of automobile wheel. As nitric acid and valuable metals are high price and toxic, they should be recovered for economics and environment. Plating waste was extracted with TBP diluted with kerosene. The concentration of nitric acid in aqueous phase was analyzed by titration method by NaOH solution (0.1~1.0N) and the amount of metals by ICP-MS and ICP-AES. The concentration of copper in plating waste were 76,850 mg/L. The concentration of nitric acid in plating waste was 1.02 M. After three step extraction was performed with 50% TBP, each organic phase was stripped three times with distilled water to obtain 48.1% of nitric acid. Purity of final nitric acid was over 99.9% by ICP analysis. After recovery of nitric acid, copper was extracted with various solvent extractors like PC 88A, D2EPHA, LIX 84 and ISE 106. Among these extractors, 92% of copper was recovered by ISE 106 after 1st extraction and 30% $H_2SO_4$ stripping. Copper ion was reduced with $N_2H_4$ to make metal powders, respectively.

A Study on Constitution of Plant Safety Inspection System for Measuring Joint Axial Force of High Tension Bolt (고장력 볼트의 체결축력 측정을 위한 설비 안전 검사 시스템 구축에 관한 연구)

  • Kim, J.Y.;Park, S.G.;Kim, H.S.;Kim, C.H.;You, S.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.15 no.2
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    • pp.371-377
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    • 1995
  • By using ultrasonic waves, we obtained conclusion from the experiment for measuring joint axial force of high tension bolt. The conclusion is followed. : From the high tension bolts used at turbine of Thermoelectric Power Plant, we obtained the equation of calculating joint axial force that is ${\sigma}=\frac{{\Delta}BPD}{j{\times}{\Sigma}{\delta}}$. By using IBM PC, which is inputed by the equation for calculating joint axial force of high tension bolts, we got joint axial force of high tension bolts form beam path of ultrasonic waves. Furrther, we can identify that constitution of plant safety inspection system is possible.

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