• 정보관리학회지
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• 제23권2호
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• pp.39-59
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• 2006

본 연구에서는 효율적인 정보접근 도구로서의 대학 웹사이트 설계를 위한 정보구조 및 카테고리 레이블을 마련하기 위해 현재 미국 문헌정보학과 웹사이트 17개를 메인메뉴구조, 하부 카테고리, 레이블링을 기준으로 분석하였다. 분석결과 메인메뉴구조는 현재 17개 조사대상 웹사이트에서 모두 공통으로 제공하고 있는 9개 카테고리로 구성하는 것이 바람직한 것으로 나타났으며 둘째, 그 다음 수준의 서브 카테고리는 9개의 카테고리의 내용의 의미를 고려해서 35개 카테고리로 나누는 것이 바람직한 것으로 나타났다. 마지막으로 카테고리 테이블로 사용되는 용어는 17개 웹사이트에서 가장 많이 사용하고 있는 용어를 사용하는 것이 바람직한 것으로 나타났다.

• International Journal of Stem Cells
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• 제17권2호
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• pp.102-112
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• 2024

An organoid is a self-organized three-dimensional structure derived from stem cells that mimics the structure, cell composition, and functional characteristics of specific organs and tissues and is used for evaluating the safety and effectiveness of drugs and the toxicity of industrial chemicals. Organoid technology is a new methodology that could replace testing on animals testing and accelerate development of precision and regenerative medicine. However, large variations in production can occur between laboratories with low reproducibility of the production process and no internationally agreed standards for quality evaluation factors at endpoints. To overcome these barriers that hinder the regulatory acceptance and commercialization of organoids, Korea established the Organoid Standards Initiative in September 2023 with various stakeholders, including industry, academia, regulatory agencies, and standard development experts, through public and private partnerships. This developed general guidelines for organoid manufacturing and quality evaluation and for quality evaluation guidelines for organoid-specific manufacturing for the liver, intestines, and heart through extensive evidence analysis and consensus among experts. This report is based on the common standard guideline v1.0, which is a general organoid manufacturing and quality evaluation to promote the practical use of organoids. This guideline does not focus on specific organoids or specific contexts of use but provides guidance to organoid makers and users on materials, procedures, and essential quality assessment methods at end points that are essential for organoid production applicable at the current technology level.

• 한국소음진동공학회논문집
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• 제13권5호
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• pp.327-333
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• 2003

Several tests are performed to evaluate road booming noise. Baseline test delivers the information of road noise characteristics. Coupling effect between structure and acoustics is obtained from the mode shapes and the natural frequencies by the modal test. Equivalent stiffness at joint areas between chassis and car-body system can be determined by the input point inertance test. Noise sensitivity of body mounting point of a chassis part can be obtained from the noise transfer function test with input point inertance test. Operational deflection shape makes us analyze the actual vibration modes of the chassis system under actual leading and find noise sources very easily. Finally, the transfer path analysis is used to Identify noise Paths through the chassis system. The objectives and the procedures of the tests are described in this Paper Also, the guideline for efficient road noise evaluation test can be found.

• 한국신뢰성학회지:신뢰성응용연구
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• 제11권1호
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• pp.59-81
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• 2011

Six Sigma has been disseminated into a variety of areas. It is believed that a stepwise understanding of Six Sigma's DMAIC is required for successes of unit projects. Meanwhile, infra-structure factors, such as leadership, organization, personnel management, educational system, etc., are also important to safely implant the Six Sigma into the whole enterprise and to thoroughly create the culture of innovation and enterprise. Careful analysis of those elements makes it possible to draw common connection between Project Management and the Six Sigma. This study drives the success elements for the successful adoption of the Six Sigma in the Korea Western Power Co., Ltd., of which management was evaluated as one of the tops based on the results of 2007 Management Innovation Assessment and arranges the similarity of like this factor and Enterprise Project Management. The results of this study are expected to provide a useful guideline for the adoption of the Six Sigma in whole company level.

• 한국경영과학회지
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• 제41권1호
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• pp.21-39
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• 2016

Although the demand for IT outsourcing (ITO) has increased recently because of the recent recession, concerns about business discontinuity in the transition phase cause companies to hesitate to adopt ITO. Therefore, a guideline to improve the prospects is needed. However, studies on the success factors of the transition phase in ITO are lacking. In this study, we develop an expert hierarchical value map (HVM) of the success of the transition phase in ITO by using cognition scientific methodologies. We empirically verify how success factors affect the success of the transition phase. Specifically, we derive an HVM of main stakeholders by using in-depth interviews and approaches, such as repertory grid technique (RGT) and laddering, based on means-end chain theory. We validate the success factors empirically through a bipolar analysis of RGT. Finally, we determine the most important cluster of success factors through cluster analysis.

• 수산해양교육연구
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• 제28권4호
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• pp.947-956
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• 2016

This study analysed the documents of Sea Area Utilization Consultation of JongChun and ApHae located in West Coast of Korea and NaJeong located in East Coast of Korea in order to find out problems of site surveys and numerical simulations for coastal erosion projects of ocean physics, and suggested the improvement way to go. Current especially like wave-induced current is the one of the important external forces to handle coastal erosion but underestimated in the west coast. In case of east coast the various tests including wave-induced current were conducted but less efficient to find out the reasons of coastal erosion. The stiffness structure to protect coastal line like beach made the secondary erosion by using them without sufficient analysis for the erosion. In order to consult a Sea Area Utilization Consultation those are needed to review the scenarios for external forces such as wave and tidal currents, the site surveys for external forces, the net sediment analysis for years, the long periods of monitoring, and the guide line and revision of the rule for coastal erosion.

• Elastomers and Composites
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• 제56권1호
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• pp.20-31
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• 2021

There is an increasing demand for the rolling resistance reduction in truck bus radial (TBR) tires in the tire industry. In TBR tires, natural rubber is used as a base polymer to prevent wear and satisfy required physical properties (cut and chip). A binary filler system (silica and carbon black) is used to balance the durability of the tire and rolling resistance performance. In this study, natural rubber (NR) compounds applied with a binary filler system were manufactured at different cure temperatures for vulcanizate structure analysis. The vulcanizate structures were categorized into carbon black bound rubber, silica silane rubber network, and chemical crosslink density by sulfur. Regardless of the cure temperature, the cross-link density per unit content of carbon black had a greater effect on the properties than silica due to affinity with NR. The relationship analysis between the mechanical, viscoelastic properties with vulcanizate structure could be a guideline for manufacturing practical TBR compounds.

• 한국정밀공학회지
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• 제22권7호
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• pp.146-154
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• 2005

Recently, the high-speed and intelligence technology of machine tools are developed for the high efficiency of productivity Under the operating condition from the high-speed of machine tools, the various failure modes can occur in core units of manufacturing system. Therefore it is for the reliability concept of machine tool to be required in a design level. And the above-stated technology must be accommodated in the feeding and spindle subsystem, etc those are the core units of machine tools. In this study, we are developed the test-bed of sliding cover (C-plate) in order to evaluating reliability and estimating failure modes of feeding subsystem under operating conditions. The reliability experiment using the developed test-bed and the additional structural analysis executed on single and double structure. We found out the weak parts of sliding cover and were able to predict a life cycle from the experiment results. In this study, we propose the new C-plate model with double link structure to apply the high-speed machine tool in the fundamental guideline.

• 통합자연과학논문집
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• 제10권3호
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• pp.141-147
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• 2017

Vascular endothelial growth factor (VEGF) is an important signaling protein involved in angiogenesis, which is the formation of new blood vessels from pre-existing vessels. Consequently, blocking of the vascular endothelial growth factor receptor (VEGFR-2) by small molecule inhibitors leads to the inhibition of cancer induced angiogenesis. In this study, we performed a two dimensional quantitative structure activity relationship (2D-QSAR) study of 38 N-Phenyl-N'-{4-(4-quinolyloxy) phenyl} urea derivatives as VEGFR-2 inhibitors based on hologram quantitative structure-activity (HQSAR). The model developed showed reasonable $q^2=0.521$ and $r^2=0.932$ values indicating good predictive ability and reliability. The atomic contribution map analysis of most active compound (compound 7) indicates that hydrogen and oxygen atoms in the side chain of ring A and oxygen atom in side chain of ring C contributes positively to the activity of the compounds. The HQSAR model developed and the atomic contribution map can serve as a guideline in designing new compounds for VEGFR-2 inhibition.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 추계학술대회논문집 I
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• pp.498-498
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• 2001

Seismic qualification of the Main Control Boards for nuclear power plants has been performed with the guideline of AS ME Section III. US NRC Reg. Guide and IEEE 344 code. The analysis model of the Main Control Boards is consist of beam. shell and mass element by using the finite element method. and, at the same time. the excitation forces and other operating loads for each model are encompassed with respect to different loading conditions. As the fundamental frequencies of the structure are found to be less than 33Hz. which is the upper frequency limit of the seismic load, the response spectrum analysis using ANSYS is performed in order to combine the modal stresses within the frequency limit. In order to confirm the structural and functional integrity of the major components, modal analysis theory is adopted to derive the required response spectrum at the component locations. As all the combined stresses obtained from the above procedures are less than allowable stresses and no mechanical or electrical failures are found from the seismic testing, it concludes the Main Control Boards is dynamically qualified for seismic conditions. Although the authors had confirmed the structural and functional integrity of both Main Control Boards and all the component, in this paper only the seismic analysis of the Main Control Board is introduced.