Purpose: Collagen membranes are used extensively as bioabsorbable barriers in guided bone regeneration. However, collagen has different effects on tissue restoration depending on the type, structure, degree of cross-linking and chemical treatment. The purpose of this study was to evaluate the inflammatory reaction, bone formation, and degradation of dehydrothermal treated porcine type I atelocollagen (CollaGuide$^{(R)}$) compared to of the non-crosslinked porcine type I, III collagen (BioGide$^{(R)}$) and the glutaldehyde cross-linked bovine type I collagen (BioMend$^{(R)}$) in surgically created bone defects in rat mandible. Methods: Bone defect model was based upon 3 mm sized full-thickness transcortical bone defects in the mandibular ramus of Sprague-Dawley rats. The defects were covered bucolingually with CollaGuide$^{(R)}$, BioMend$^{(R)}$, or BioGide$^{(R)}$ (n=12). For control, the defects were not covered by any membrane. Lymphocyte, multinucleated giant cell infiltration, bone formation over the defect area and membrane absorption were evaluated at 4 weeks postimplantation. For comparison of the membrane effect over the bone augmentation, rats received a bone graft plus different covering of membrane. A $3{\times}4$ mm sized block graft was harvested from the mandibular angle and was laid and stabilized with a microscrew on the naturally existing curvature of mandibular inferior border. After 10 weeks postimplantation, same histologic analysis were done. Results: In the defect model at 4 weeks post-implantation, the amount of new bone formed in defects was similar for all types of membrane. Bio-Gide$^{(R)}$ membranes induced significantly greater inflammatory response and membrane resorption than other two membranes; characterized by lymphocytes and multinucleated giant cells. At 10 weeks postoperatively, all membranes were completely resorbed. Conclusion: Dehydrotheramal treated cross-linked collagen was safe and effective in guiding bone regeneration in alveolar ridge defects and bone augmentation in rats, similar to BioGide$^{(R)}$ and BioMend$^{(R)}$, thus, could be clinically useful.
Purpose : The purpose of this study is to prevent thc graft-tunnel mismatch by measuring the patellar tendon length, intertunnel distance, tibial tunnel length and by obtaining appropriate bone block length. Materials and Methods : Authors analyzed 15 patients who had taken the anterior cruciate ligament reconstruction from March 1997 to June 1999. Tibial guide was always set on the "endo" $40^{\circ}$ position(Acufex, MA, USA). We measured the following indices, intertunnel distance(X), tibial tunnel length(T), patellar tendon length(N), tibia bone plug length(Y). Both of the femoral tunnel length(F) and the patellar bone plug length(P) were made in 25mm. The appropriate tibial bone plug length was simply calculated by subtracting the patellar tendon length from the sum of the intertunnel distance and thc tibial tunnel length(Y=X+T-N). Results : The average indices were as follows ; the intertunnel distance(X) was $23.4{\pm}1.4mm$, the tibial tunnel length(T) was $43.6{\pm}1.7mm$, the patellar tendon length was $40{\pm}2.4mm$, and the tibia bone plug length was $27{\pm}2.4mm$. Conclusion : In authors' endoscopic technique, establishment of individually determined optimal tibial bone plug length, based on total tunnel length and patellar tendon length could prevent the problem of graft-tunnel mismatch.
Among imaging and treatment devices for small animals, positron emission tomography(PET) causes a change in spatial resolution within a field of view. This is a phenomenon caused by using a small gantry and a thin and long scintillation pixel, and detectors that measure the interaction depth are being developed and researched to solve this problem. In this study, a detector that measures the interaction depth was designed using several scintillator blocks and light guides with different reflector patterns. The scintillator block composed of 4 × 4 arrays of 3 mm × 3 mm × 5 mm scintillation pixels formed four layers, and a light guide was inserted in each layer to configure the entire detector. In order to check whether the interaction depth was measured, a gamma ray interaction was generated at the center of all scintillation pixels to acquire data and then reconstructed into a flood image. The reflector patterns of the light guides inserted between the layers were all different, so the positions of the scintillation pixels for each layer were formed in different locations. It is considered that even spatial resolution can be achieved over all regions of the field of view if all positions of the scintillation pixels thus formed are separated and used for image reconstruction.
Kim, Sung-Jo;Kim, Se-Yun;Ji, Yongsoo;Kim, Bongsik;Han, Tong-Seok
Journal of the Computational Structural Engineering Institute of Korea
/
v.33
no.5
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pp.311-318
/
2020
This study introduces a technique for improving the elastomeric-isolator performance using modular devices. The modular devices are shear resistance block, polymer spring, displacement acceptance guide, and anti-falling block. They are installed on the elastomeric isolator as a supplementary device. Each modularized device improves the isolator performance by performing step-by-step actions according to the seismic intensity and displacement. The PRB isolation device works in four stages, depending on the seismic magnitude, to satisfy the target performance. It is designed to accommodate design displacement in the first stage and large magnitude of earthquakes in the second and third stages. This design prevents superstructures from falling in the fourth stage due to large-magnitude earthquakes by increasing the capacity limit of the elastomeric isolator. In this study, the PRB isolation device is analyzed using finite element analysis to verify that the PRB isolation device works as intended and it can withstand loads corresponding to large-magnitude earthquakes. The performance of the PRB isolation device is validated by the analysis, which is further corroborated by actual experiments.
The major structures characteristic of the Taebaegsan sedimentary basin were regionally analyzed with special reference to its southeastern extension to the Yeonhwa-Ulchin district of economic interest in zinc-lead mineralization. The basin geometry, basement setting, sedimentary components, and the characteristics of deformation and igneous activity of the Taebaegsan basin differ basically from those of the adjacent mobile belt of the Ogcheon geosyncline, although the latter affected the basin's western side considerably. The subrectangular shape of the Taebaegsan basin reflects the checkered pattern of basement-block arrangement, and the carbonate-dominated lithologic components of the basin-fill indicate a cratonic depositional setting, which is comparable to some of the North American mid-continental craton. The Taebaegsan basin, however, has somewhat been less stable than the North American megacraton that is reflected in the former's thicker sedimentary fill and steeper faults of later deformation, showing a tendency to increase in thickness close to the basement-block boundaries, which may indicate contacts of possibly detached cratonic blocks of Precambrian age; these weak zones of block boundaries have been the loci of repeated sedimentation, deformation and related igneous intrusions. A series of downthrown or uplifted tilted blocks, in which the Cambro-Ordovician sedimentary wedges and the late Cretaceous to early Tertiary igneous intrusives are involved, occurs intermittently across the Yeonhwa-Ulchin district in a noticeable pattern of en echelon type. These sedimentary wedges are correlated to the Cambro-Ordovician section of the Hambaeg syncline to the west in stratigraphy and lithology, and are considered to have resulted from the northeastern and/or northwestern cross-faulting of the pre-existing syncline belt of easterly trend, extended from the main portion of the Hambaeg syncline. These structural junctions (or intersections) of the earlier syncline belt and the later cross-faults have been acted as a guide to ascending igneous materials and hydrothermal ore-forming fluids to form a zone of zinc-lead skarn deposits across the Yeonhwa-Ulchin district showing a stepwise recurrence of these deposits toward the east.
Moon, Sang Ho;Lee, Song;Jung, Jae-Hyun;Shin, Won Shik
The Journal of Korean Orthopaedic Ultrasound Society
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v.7
no.1
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pp.33-38
/
2014
Purpose: To determine the therapeutic effectiveness of ultrasound-guided medial branch block (MBB) for the herniated lumbar disc patients who did not relieve their symptoms after percutaneous epidural neuroplasty (PEN). Materials and Methods: From August 2011 to February 2013, 559 patients with herniated lumbar disc have undergone PEN. Among them, ultrasound-guided MBBs were performed for the patients who had sustained low back pain and refered pain to lower extremities. Eighty eight patients were followed at 1 month and 39 patients could be followed at 6 month. All procedures have been performed by the one operator, and 23 G, 10 cm needle was placed and 0.5% lidocaine was injected under ultrasound guide. To target medial branches from L1 to L5, the groove at the root of transverse process and the base of superior articular process has been identified on transverse scan. Patients were evaluated by Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) at each follow-up. Significant pain relief was described as a 50% or more reduction in VAS and significant improvement in function was described as at least a 40% reduction in ODI. Results: VAS showed that preprocedure pain ($7.35{\pm}1.68$; $mean{\pm}SD$) significantly decreased 1 month after block ($3.36{\pm}2.98$) and 6 month ($3.05{\pm}2.27$) (p<0.05). ODI also showed that preprocedure score ($32.82{\pm}8.77$) significantly decreased at 1 month ($15.14{\pm}14.01$) and 6 month ($12.97{\pm}8.82$) (p<0.05). Significant pain relief was observed in 64.49% at 1 month and 64.10% at 6 month. Significant functional improvement in 59.81% at 1 month and 61.54% at 6 month. Conclusion: Ultrasound-guided medial branch block may sufficiently treat the facet problems secondary from disc disease.
This study was done to develop environmental risk assessments and a biosafety guide for insect-resistant genetically modified rice at a LMO (Living Modified Organism) isolation field. In the LMO quarantine area of Kyungpook National University, the species diversities and population densities of non-target insects found on insect-resistant genetically modified rice (Bt-9) resistant to Cnaphalocrocis medinalis and on non-GM rices (Dongjin and Ilmi) were investigated. The Bt-9 event was therefore evaluated under field conditions to detect possible impacts on the above ground insects and spiders. The study compared transgenic rice and two non-GM reference rices, Ilmi and Dongjin, at Gunwi in Southern Korea in 2016. Each rice was grown on three $18m^2$ plots with a randomized block design. A total of 4,243 individuals from 43 families and 9 orders were collected from the LMO isolation field. In the three types of rice fields, a total of 1,467 individuals from the insect-resistant genetically modified rice (Bt-9), 1,423 individuals from the Ilmi, and 1,353 individuals from the Dongjin were collected, respectively. There was no difference between the population densities of the non-target insect pests, natural enemies and other insects on the insect-resistant genetically modified rice (Bt-9) and non-GM rices. These results provide the diversity and population density of non-target insects for an environment risk assessment survey on insect-resistant genetically modified rice and could be used as a guideline to make a biosafety assessment method for genetically modified crops.
Transactions of the Korean Society of Mechanical Engineers A
/
v.36
no.6
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pp.681-689
/
2012
In this study, we performed a simulation of the dynamic response of a multibody system to calculate the tension acting on wire ropes connecting floating cranes and a heavy cargo such as a Giga Block weighing over 5000 tons when the cargo is salvaged using parallel connected floating cranes. In this simulation, we supposed that the motion of the floating cranes, barge ship, and heavy cargo has 6 degrees of freedom and that the interaction is determined by constraints among them. In addition, we considered independent hydrostatic and hydrodynamic forces as external forces acting on the floating cranes and barge ship. The simulation result can be a basis for verifying the safety of construction methods in which heavy cargo is salvaged by parallel connected floating cranes, and it can also be used to guide the development of such construction methods.
The purpose of this study is to provide basic information and guide line for designing hotels located in metropolis by analyzing the spatial configuration of public area. As the sample of analysis, ten hotels are selected in Tokyo area, which were constructed during 1970 to 1990; the period was characterized by booming hotel constructions. The findings of the above analytical survey might be summarized as follows. First of all, it was found that all hotels constructed during the above mentioned periods could be classified into two categories according to their block type such as interlocking form and form within form types. It also observed the six hotels out of then had adopted form within form, beside, the left four hotels were constructed along the interlocking form type. Secondly, as regard to the functional space configuration of the public area, it was found that, in case of eight hotels, the upper part of the building which allocated as residential quarter are configured as linear type. As regard the lower part, however, it was found that different types are adopted. For instance, five hotels had adopted con-course types for the lower level that is spared for the public/service area. Beside, it was also found that, out of above five hotels, three hotels took form within type and the other two adopted compromising type. Thirdly, as regard to the composition of public area, it was found that, the quarters are allocated as follows, such as 34.11 percent for public, 28.99 percent for sales and 33.07 percent for service quarter.
Journal of the Korean Institute of Rural Architecture
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v.20
no.2
/
pp.49-56
/
2018
The vernacular houses with 田-shaped floor plan at Gangreung have been played important roles in tracing the vernacular living cultures including housing life. But due to the adoption of convenient facilities in vernacular housing lives caused by modernization and urbanization, many changes and transformations have happened at residential space of vernacular houses. This thesis targets to extract basic data to prepare and prevent various problems in process of renovation, extension and function change as installing housing life facilities, and to identify the changes and transformations of them to prepare the proper balances between their original form preservation and residents' convenience living. The results are as follows. The inner wall removal of rooms, the fuel change of cooking and heating, the leveling change of kitchen floor made possible the sedentary lifestyles. And its residential rooms were transformed from two row to one row by inner wall removal, the fuel heating change, the heating method change and the heat insulating materials. The residential extension materials were changed from the traditional materials such as soil, wood, etc to the modern materials such as cement block or brick, sandwich panel, etc. And the modern materials were used and attached to widen residential spaces to the vernacular house because of the easiness of execution. So, it is necessary for 田-shaped floor plan vernacular house owners to distribute printed execution guide book to prevent and minimize the various problems to be shown by extension, renovation and function change.
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