• Physical Therapy Korea
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• v.14 no.3
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• pp.32-40
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• 2007

Although many children with cerebral palsy have problems with their eye movements available data on its intervention is minimal. The purpose of the study was to determine the effectiveness of the postural movement normalization and eye movement program on the oculomotor ability of children with cerebral palsy. Twenty-four children with cerebral palsy (12 male and 12 female), aged between 10 and 12, were invited to partake in this study. The subjects were randomly allocated to two groups: an experimental group received the postural movement normalization and eye movement program and a control group which received conventional therapy without the eye movement program. Each subject received intervention three times a week for twelve weeks. The final measurement was the ocular motor computerized test before and after treatment sessions through an independent assessor. Differences between the experimental group and control group were determined by assessing changes in oculomotor ability using analysis of covariance (ANCOVA). The changes of visual fixation (p<.01), saccadic eye movement (p<.01) and pursuit eye movement (p<.01) were significantly higher in the experimental group than in the control group. These results show that the postural movement normalization and eye movement program may be helpful to treat children with cerebral palsy who lose normal physical and eye movement.

• Journal of Korea Multimedia Society
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• v.25 no.4
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• pp.575-582
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• 2022

In the manufacturing environment, research to minimize robot collisions with human beings have been widespread, but in order to interact with robots, it is important to precisely recognize and predict human actions. In this research, after enhancing performance by applying group normalization to the Hourglass model to detect the operator motion, the skeleton was estimated and data were created using this model. And then, three types of operator's movements were recognized using LSTM. As results of the experiment, the accuracy was enhanced by 1% using group normalization, and the recognition accuracy was 99.6%.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.16 no.3
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• pp.135-140
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• 2016

Purpose: Galactose is metabolized to galactose-1-phosphate by galactokinase (GALK), galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4-epimerase (GALE), and galactosemia occurs when each enzyme is deficient. In Korea, unlike foreign countries, classic galactosemia is rare and transient galactosemia due to GALK hyperactivity is reported, but studies on frequency, clinical significance, and genetic variation are lacking. In this study, we analyzed the clinical characteristics of patients with galactosemia due to GALK hyperactivity. Methods: We investigated 85 patients who had an elevated galactose level in the neonatal screening test without deficiency of enzymes at Department of Pediatrics, Seoul & Bucheon Soonchunhyang University Hospital from January 2008 to June 2016. We investigated the level of galactose, galactose-1-phosphate, GALK and duration of galactose normalization, and analyzed the correlation between GALK elevation and galactose, galactose-1-phosphate and duration of galactose normalization. And the levels of galactose, galactose-1-phosphate, and duration of galactose normalization were compared between the galactose-free formula feeding group and non-feeding group. Results: Mean age of visit was $26.7{\pm}16.1days$. Duration of galactose normalization was $35.3{\pm}20.5days$. Mean galactose level was $18.5{\pm}7.3mg/dL$ in the neonatal screening and follow-up galactose level in serum was $2.3{\pm}5.4mg/dL$. The mean value of galactose-1-phosphate was $6.0{\pm}4.7mg/dL$ and the mean GALK level was $3.84{\pm}1.28{\mu}mol/Hr/gHb$. There was no significant correlation between GALK levels and galactose levels in the neonatal screening test (P=0.351), and we analyzed the correlation between GALK levels and follow-up galactose levels in serum, there was no significant correlation (P=0.101). There was a significant correlation between GALK levels and galactose-1-phosphate (P=0.015), and the correlation between GALK levels and duration of galactose normalization was not statistically significant (P=0.176). 49% of the patients were fed galactose-free formula, and 45% were not. Galactose and galactose-1-phosphate levels in the neonatal screening test were statistically significantly higher (P=0.004, 0.034) in using galactose-free formula group. Duration of galactose normalization was not related to the use of galactose-free formula (P=0.266, 0.249). Conclusion: Galactosemia due to GALK hyperactivity seems to be a temporary phenomenon and may not require galactose restriction. More research is needed on the role of the nuclear protein, racial traits and genetic variations in Korean patients.

• The Korean Journal of Applied Statistics
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• v.22 no.3
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• pp.585-594
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• 2009

Researchers of microarray experiment transpose processed images of raw data to possible data of statistical analysis: it is preprocessing. Preprocessing of microarray has image filtering, imputation and normalization. There have been studied about several different methods of normalization and imputation, but there was not further study on the order of the procedures. We have no further study about which things put first on our procedure between normalization and imputation. This study is about the identification of differentially expressed genes(DEG) on the order of the preprocessing steps using two-dye cDNA microarray in colon cancer and gastric cancer. That is, we check for compare which combination of imputation and normalization steps can detect the DEG. We used imputation methods(K-nearly neighbor, Baysian principle comparison analysis) and normalization methods(global, within-print tip group, variance stabilization). Therefore, preprocessing steps have 12 methods. We identified concordance measure of DEG using the datasets to which the 12 different preprocessing orders were applied. When we applied preprocessing using variance stabilization of normalization method, there was a little variance in a sensitive way for detecting DEG.

• Journal of the Korean Society of Food Culture
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• v.34 no.3
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• pp.325-333
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• 2019

This study was a qualitative investigation of the process of adaptation of nutrition education programs by marriage immigrant women who completed education programs for training of food citizen leaders. Focus group interviews of seven marriage immigrant women from Vietnam, China, Mongolia and Russia were conducted and analyzed based on the Normalization Process Theory (NPT). Participants were aware of the purpose of the education program (coherence) and their confidence in organizing and reconstructing the knowledge of nutrition was increased after education (reflexive monitoring). However, they had difficulties attending long-term education programs (cognitive participation) and overcoming language barriers (collective action). Although the program was beneficial for the participants in that they could apply acquired nutrition knowledge to their everyday life as food citizen leaders, the continuous monitoring and feed-back system (management), customized application, and consideration of personal and social factors need to be developed and facilitated. In addition, various programs targeting marriage immigrant women may increase economic independence of these women. The NPT proved beneficial in conceptualizing the barriers and facilitators to implementing nutrition education. The successful implementation of nutrition intervention needs special support to overcome barriers to cognitive participation and collective action.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.3
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• pp.615-622
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• 2007

In general, Harris detector is commonly used for finding salient points in watermarking systems using feature points. Harris detector is a kind of combined comer and edge detector which is based on neighboring image data distribution, therefore it has some limitation to find accurate salient points after watermark embedding or any kinds of digital attacks. In this paper, we have used cross reference points which use not data distribution but geometrical structure of a normalized image in order to avoid pointing error caused by the distortion of image data. After normalization, we find cross reference points and take inverse normalization of these points. Next, we construct a group of triangles using tessellation with inversely normalized cross reference points. The watermarks are affine transformed and transformed-watermarks are embedded into not normalized image but original one. Only locations of watermarks are determined on the normalized image. Therefore, we can reduce data loss of watermark which is caused by inverse normalization. As a result, we can detect watermarks with high correlation after several digital attacks.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5279-5284
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• 2015

Background: The study analyzed the long term clinical outcomes of pituitary adenoma cases treated with the first Thailand installation of a dedicated Linac-based stereotactic radiation machine (X-Knife). Materials and Methods: A retrospective review of 115 consecutive pituitary adenoma patients treated with X-Knife at the Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand from 1997 to 2003 was performed. Stereotactic radiosurgery (SRS) was selected for 21 patients (18%) including those with small tumors (${\leq}3cm$) located ${\geq}5mm$. from the optic apparatus, whereas the remaining 94 patients (82%) were treated with fractionated stereotactic radiotherapy (FSRT). Results: With a median follow-up time of 62 months (range, 21-179), the six-year progression free survival was 95% (93% for SRS and 95% for FSRT). The overall hormone normalization at 3 and 5 years was 20% and 30%, respectively, with average time required for normalization of approximately 16 months for SRS and 20 months for FSRT. The incidence of new hypopituitarism was 10% in the SRS group and 9% in the FSRT group. Four patients (5%) developed optic neuropathy (1 in the SRS group and 3 in the FSRT group). Conclusions: Linac-based SRS and FSRT achieved similar high local control rates with few complications in pituitary adenoma cases. However, further well designed, randomized comparative studies between SRS versus FSRT particularly focusing on hormone normalization rates are required.

• Journal of Acupuncture Research
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• v.26 no.5
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• pp.57-63
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• 2009

Objectives : Since the Front Points are treated as response zone, it can be used for the diagnosis and treatment of disease in viscera and bowels. Jeonjung($CV_{17}$) is the Front Point of SIMPO, it is related with cardiovascular, neuro-psychiatrical disease in aspect of Oriental Medicine. This research is for clarifying relations with palpation of the Jeonjung($CV_{17}$) and autonomic nerve system by comparing HRV and SRI(Stress Reaction Index). Methods : This study was proceeded for three months, from June 2009 to September 2009. Among 31 healthy volunteers, 13 subjects who complained the pressure pain around Jeonjung($CV_{17}$) are classified pressure pain group and 18 subjects who had no pain around Jeonjung($CV_{17}$) as normal group. All subjects had their HRV(SA-2000E: Medicore Co..Ltd. Korea) and SRI measured at visit. We studied the difference of HRV between two groups.(Statistics by Student t-test, p<0.05) Results : LF normalization of the pressure pain group were significantly higher than those of the normal group. HF normalization of the pressure pain group were significantly lower than those of the normal group. Compared with those of the normal group, total SRI of the pressure pain group were low but it's not significant. Conclusions : The results of HRV of the pressure pain group show that pressure pain around Jeonjung($CV_{17}$) is related to mental stress and autonomic disturbance.

• Journal of Oriental Neuropsychiatry
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• v.17 no.2
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• pp.133-145
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• 2006

Objective : The purpose of this experimental-controlled study was to investigate the characteristics of the autonomic nervous system in students with Keongke by using HRV(Heart rate variability) and PSV(Pupil size variability). Method : The study group was consisted of 11 students with self recognition as the experimental group, and 25 normal students as the control group. Informations on gender and age were obtained by medical charts and personal interviews. By using heart rate variability and pupil size variability, we measured the value of HRT(Heart rate), SDNN(Standard deviation of NN intervals), LFnorm(Low frequency normalization), HFnorm(High frequency normalization), LF/HF ratio, Pupil area, B.S.(Basic size), C.R.(Max Constriction Rate) and 1s.d.(1sec Dilation Rate). I compared the degrees of the sympathetic and parasympathetic activity. Result : 1. In the result of heart rate variability between experimental and control group, none of the parameters of experimental group were significantly different from control group. And even though there were no statistical significance, there were some numerical differences in SDNN, LF norm, HF norm. 2. In pupil size variability, C.R. and 1s.d. of the experimental group were increased compared to control group. Conclusion : The study results suggest that the group with Keongke has differences of autonomic nervous system as compared to those in normal state. Measurement value of PSV is a new technical approach to estimate the autonomic nervous system.

• Journal of the Korean Mathematical Society
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• v.42 no.1
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• pp.65-83
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• 2005

In this paper, we prove that the two well-known natural normalizations of Hamiltonian functions on the symplectic manifold ($M,\;{\omega}$) canonically relate the action spectra of different normalized Hamiltonians on arbitrary symplectic manifolds ($M,\;{\omega}$). The natural classes of normalized Hamiltonians consist of those whose mean value is zero for the closed manifold, and those which are compactly supported in IntM for the open manifold. We also study the effect of the action spectrum under the ${\pi}_1$ of Hamiltonian diffeomorphism group. This forms a foundational basis for our study of spectral invariants of the Hamiltonian diffeomorphism in [8].