• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.6
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• pp.212-220
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• 2013

Recently, there has been tremendous increase in human-computer/machine interaction system, where the goal is to provide with an appropriate service to the user at the right time with minimal human inputs for human augmented cognition system. To develop an efficient human augmented cognition system based on human computer/machine interaction, it is important to interpret the user's implicit intention, which is vague, in addition to the explicit intention. According to cognitive visual-motor theory, human eye movements and pupillary responses are rich sources of information about human intention and behavior. In this paper, we propose a novel approach for the identification of human implicit visual search intention based on eye movement pattern and pupillary analysis such as pupil size, gradient of pupil size variation, fixation length/count for the area of interest. The proposed model identifies the human's implicit intention into three types such as navigational intent generation, informational intent generation, and informational intent disappearance. Navigational intent refers to the search to find something interesting in an input scene with no specific instructions, while informational intent refers to the search to find a particular target object at a specific location in the input scene. In the present study, based on the human eye movement pattern and pupillary analysis, we used a hierarchical support vector machine which can detect the transitions between the different implicit intents - navigational intent generation to informational intent generation and informational intent disappearance.

• Journal of the Korean Chemical Society
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• v.58 no.6
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• pp.575-579
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• 2014

Development of liposomes has been actively studied for effective delivery of drug at tumor site. However, despite their preferential accumulation at tumor site, the therapeutic efficacy of such liposomal drug has been limited because of low drug release. Therefore, we developed a temperature-sensitive liposome (TSL), which can be made to maximize release of drug by external stimulation such as ultrasound. Doxorubicin (DOX) as a model drug was encapsulated into TSL by a pH gradient method. The particle size of the TSL was $142.0{\pm}6.24nm$. Surface charge was $-10.55{\pm}1.12mV$. Release of drug from TSLs was up to 80% within 15 min at over $42^{\circ}C$ measured by fluorescence intensity. Cytotoxicity of released DOX from TSLs with ultrasound was highly increased compared to TSLs without ultrasound. Taken together, we demonstrate that temperature sensitive drug release from TSLs with ultrasound, which may be useful for cancer therapy to increase drug concentration at tumor site by external stimulation.

• Korean Journal of Agricultural Science
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• v.14 no.2
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• pp.413-421
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• 1987

The objective of this study was to evaluate the possibility of sex preselection by gradients methods using bovine serum albumin in rabbits. Artificial insemination with separated sperm was performed, after highly motile sperm were separated by different methods using 6%, 10% and 20% bovine serum albumin. Various characteristics of separated sperm, and the conception rate and secondary sex ratio at artificial insemination with sperm separated by different methods were compared. The results obtained were as follows. 1. The conception rate of sperm separated by bovine serum albumin gradients was higher than th at of control sperm. But secondary sex ratio was not altered by this methods. 2. The sperm separated by bovine serum albumin gradients showed significantly high value in motility, percent of normal sperm and progressive motility as compared with control sperm and revealed the highest sperm recovery when separated with 6% bovine serum albumin. 3. The sperm motility, percent of normal sperm and progressive motility of the highly motile sperm frozen after being separated from raw semen with bovine serum albumin, showed significantly high value than those of control sperm.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.29 no.5
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• pp.483-490
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• 2016

In plant industry, sulfur storage tank is made of steel and annular plate is connected with concrete foundation of ring wall type by anchor bolt. Due to keep sulfur at high temperature in tank by coil, sulfur storage tank is expanded larger than another tank stores fluid at room temperature. Generally, structural design of tank foundation is performed analysis with loading of temperature gradient between inner and outer surface, this method can't consider the phenomenon that load is intensively transferred to concrete foundation at anchor bolt. This means that temperature load is underestimated and causes crack of concrete near anchor bolt. In this study, evaluation formula considering temperature load transfer mechanism through anchor bolt is proposed and load acting on concrete foundation is rationally decided. For this purpose, it is analyzed variation of thermal load per various anchor bolt number using finite element model including tank annular plate and anchor bolt. Solution is proposed as specified term combining result of analysis and theoretical solution for evaluating load transferred by anchor bolt. For confirmation of validation of proposed formula, it is applied in design of sulfur storage tank at plant site, it shows that the formula can be practically applied.

• Korean Journal of Environment and Ecology
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• v.29 no.5
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• pp.651-680
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• 2015

In order to investigate vertical plant distribution on Namdeogyu of Mt. Deogyu National Park by temperature change, vascular plants of nine areas with 100-meter-high difference were surveyed from the Deogsangyo (650m alt.) to the Namdeogyusan (1,507m alt.). A total of 455 taxa belonging to 99 families, 280 genera, 402 species, 5 subspecies, 43 varieties, 4 forms and 1hybrid were vegetated on survey areas. Around 700 m high did species diversity of vascular plants decrease rapidly. The Detrended correspondence analysis (DCA) divided distribution of vascular plants into five groups; areas below 700m alt., 700~1,100m alt., 1,100~1,300m alt., and areas above 1,300m alt.. These results showed that vegetation of vascular plants on investigated areas has high correlation with climate elements of temperature. Vascular plants should be crowded within their own optimal ranges of vegetation. Climate change would result in shift of these distribution ranges, and thus vegetation shift will be happened accordingly.

• Korean Journal of Environment and Ecology
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• v.26 no.2
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• pp.156-185
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• 2012

In order to investigate vertical plant distribution on Osaek valley of Mt. Seorak by temperature change, vascular plants of fourteen areas with 100-meter-high difference were surveyed from the Osaekgyo(345m alt.) to the Daecheongbong(1708m alt.). A total of 449 taxa belonging to 94 families, 279 genera, 397 species, 5 subspecies, 45 varieties, and 2 forma were vegetated on survey areas. Around 500 m high did species diversity of vascular plants decrease rapidly. The Detrended correspondence analysis(DCA) divided distribution of vascular plants into five groups; areas below 500m alt., 500~900m alt., 900~1400m alt., 1,400~1,600m alt., and areas above 1,600m alt.. These results showed that vegetation of vascular plants on investigated areas has high correlation with climate elements of temperature. Vascular plants should be crowded within their own optimal ranges of vegetation. Climate change would result in shift of these distribution ranges, and thus vegetation shift will be happened accordingly.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.4
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• pp.333-340
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• 2019

This study attempted to eatablish a high performance liquid chromatography (HPLC) analysis method for the determination of avicularin, quercitrin as a part of the quality control for the development of functional cosmetic materials from Astilbe chinensis extract. HPLC was performed on a Capcell Pak C₁₈ MGII column with a gradient elution of 0.05% (v/v) trifluoroacetic acid (TFA) and acetonitrile at a flow rate of 1.0 mL/min at 30 ℃. The analyte was detected at 254 nm. The HPLC method was performed in accordance with the international conference on harmonization (ICH) guideline (version 4, 2005) of analytical procedures with respect to specificity, precision, accuracy, and linearity. The limits of detection and quantitation of avicularin and quercitrin were 0.094 and 0.285 mg/mL, 0.031 and 0.095 mg/mL respectively. Calibration curves showed good linearity r² > 0.99990 for avicularin and r² > 0.99994 for quercitrin. Precision of analysis was satisfied with less than 0.59% for avicularin and 0.63% for quercitrin. Recoveries of quantified compounds ranged from 100.97 to 101.77% for avicularin and 100.18 to 100.32% for quercitrin. These result indicated that the established HPLC method is very useful for the determination of marker compounds in A. chinensis extracts.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.10 no.3
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• pp.177-184
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• 2000

The effect of the buyancy and thermocapillarity for differnent aspect ratio of flow field on melt motion and mass transfer has been numerically investigated in magnetic Czochralski crystal growth of silicon. During the process of crystal growth, the melt depth of crucible reduces so the aspect ratio of flow field also reduces. Therefore the shape of magnetic field of the flow field changes and the flow pattern also changes significantly. Together with the melt flow which forms the Marangoni convection (or thermocapillary flow) that comes from the inside the flow field, a flow circulation is observed near the corner close both to the crucible wall and the free surface. Due to this circulation, buoyancy effect has been turned out to be local rather than global. As the aspect ratio decreases, the radial component of the magnetic field prevails compared with the axial component in the flow field. Under the influence of this magnetic field, the melt flow and the temperature distribution in a meridional plane tend to depend on the radial position. As the aspect ratio decreases, the temperature gradient near the edge of the crystal decreases yielding smaller thermocapillarity, and the oxygen concentration near the crystal and the oxygen incorporation rate also decrease.

• Journal of Korean Society of Forest Science
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• v.96 no.1
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• pp.107-114
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• 2007

Establishments of the seedlings inside the natural forest from adjacent artificial forests would be an important factor in forest stand dynamics. This study was conducted to see the invasion of Korean pine (Pinus koraiensis) seedlings which is not native in this region, into the natural deciduous broad-leaved forest in Gwangneung, Korea. There is no mother tree at the I ha study site while the number of naturally regenerated P. koraiensis seedlings was 345 trees and 56% of them were clumped with more than two seedlings at each point. Applying the image segmentation method to IKONOS satellite image of January, 2003, the distance from the center of 1 ha study site to the nearest mother tree and plantation of Korean pine were 200 m and 270 m, respectively. The average height and root-collar diameter of the seedlings were 34 em and 7 mm, respectively and the age of 207 seedlings (60%) were below 5 years old. Most abundant range of soil moisture gradient and LAl (leaf area index) were from 16 to 20% and those of LAI were from 3.1 to 3.5. To understand the dynamics and seed dispersal pattern of Korean pine in the Gwangneung natural deciduous broad-leaved forests, additional studies not only long-term monitoring of growth and mortality of naturally regenerated Korean pine seedlings but also application of stable isotope analysis and molecular genetic techniques was recommended.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.10
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• pp.75-80
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• 2017

In this paper, we describe the effect of the regularization method and the network with identity mapping on the performance of the activation functions in deep convolutional neural networks. The activation functions act as nonlinear transformation. In early convolutional neural networks, a sigmoid function was used. To overcome the problem of the existing activation functions such as gradient vanishing, various activation functions were developed such as ReLU, Leaky ReLU, parametric ReLU, and ELU. To solve the overfitting problem, regularization methods such as dropout and batch normalization were developed on the sidelines of the activation functions. Additionally, data augmentation is usually applied to deep learning to avoid overfitting. The activation functions mentioned above have different characteristics, but the new regularization method and the network with identity mapping were validated only using ReLU. Therefore, we have experimentally shown the effect of the regularization method and the network with identity mapping on the performance of the activation functions. Through this analysis, we have presented the tendency of the performance of activation functions according to regularization and identity mapping. These results will reduce the number of training trials to find the best activation function.