• Title/Summary/Keyword: Goat aorta

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Distribution of Renal Artery within Kidney of Korean Native Goat (한국재래산양(韓國在來山羊)의 신동맥(腎動脈)의 분포상태(分布狀態))

  • Kim, Yong Keun;Kim, Chong Sup;Kim, Moo Kwang
    • Korean Journal of Veterinary Research
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    • v.15 no.1
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    • pp.127-131
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    • 1975
  • By employing the vinylite-and neoprene latex-corrosion technique, ramification and arrangement of A. renalis were observed in fifty Korean native goats (100 kidneys). The obtained results were as follows: 1. A single renal artery, arising on each side from abdominal aorta, bifurcated into Ramus dorsalis and Ramus ventralis from which 3~6 segmental arteries originated. 2. The dorsal and ventral surfaces of the kidney were divided separately into 3~6 arterial segments by the running of the segmental artery into the parenchyma. Of them four segments were mostly frequent (in 77% of right kidney and 83% of left). 3. In 25 of all the kidneys, either dorsal or ventral surface of a kidney was supplied from interlobar or segmental arteries belong to the opposite Ramus. 4. In 3 goats, A. polaris superior was observed. 5. Generally, distribution of the renal artery of Korean native goat resembled that of the dog.

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N-Phenyl-3-Pyridin-2-yl Imino Derivatives as Vascular Smooth Muscle Relaxants: Potential Phosphodiesterase V Inhibitors

  • Choudhari, Prafulla;Bhatia, Manish;Bhatia, Neela
    • Bulletin of the Korean Chemical Society
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    • v.34 no.9
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    • pp.2707-2710
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    • 2013
  • The present communication deals with development of ten novel N-Phenyl-3-Pyridin-2-yl imino derivatives as vascular smooth muscle relaxants. The derivatives were prepared and optimized using pocket modelling and pharmacophore modelling. The 4 hydroxy substituted derivatives are showed potent activity comparable to the sildenafil.

Comparison of Different Methods of Aortic Valve Conduit Xenograft Preservation in an Animal Experiment Model; Fresh Cryopreservation versus Acellularized Cryopreservation (동물 실험 모델에서 적용한 이종대동맥판막도관의 조직보존방법 비교; 신선 냉동보존과 무세포화 냉동보존)

  • Kim, Chang Young;Kim, Kyung-Hwan;Moon, Kyung Chul;Kim, Woong-Han;Sung, Si-Chan;Kim, Yong-Jin
    • Journal of Chest Surgery
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    • v.43 no.1
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    • pp.11-19
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    • 2010
  • Background: The commercially used vascular xenografts have some problems such as calcification, fibrosis and tissue degeneration that are associated with inflammatory and immunologic reactions. We compared two methods of xenograft preservation (fresh cryopreservation versus acellularized cryopreservation) of goat aorta. Material and Method: Aortic valved xenografts were harvested from adult pigs, and these were preserved using fresh cryopreservation (FC group, n=4) or acellularized crypreservation (AC group, n=4). These xenografts were implanted into adult goats. There were 2 short-term survivors (less than 100 days) and 2 long-term survivors in each group. These xenografts were explanted and they underwent microscopic examination. Result: The goats survived 31, 40, 107 and 411 days in the FC group and the other goats survived 5, 40, 363 and 636 days in the AC group. All the short-term survivors in each group expired because of rupture at the proximal anastomosis site. Marked neutrophil infiltration was observed in the FC group FC and lymphocytes were observed in the AC group. There were no differences in the occurrence of calcification, fibrosis and thrombosis among the groups. Conclusion: Some goats survived more than 100 days after the xenograft implantation irrespective of the methods of preservation. Because severe tissue degeneration developed in both groups, we think these methods are not appropriate for xenograft preservation of aorta. It was worth a preliminary trial for improving the preservation method or to modify the processing of xenografts.