• 대한간호학회지
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• 제44권5호
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• pp.593-593
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• 2014

• 보건교육건강증진학회지
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• 제25권1호
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• pp.55-69
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• 2008

Objective: This study was to investigate the relationship between hemoglobin A1c level and self-reported oral health status. Methods: The subjects of this study were 150 diabetic patients (60 male patients and 90 female patients) who went to the internal and family medicine departments of clinic. This study used the questionnaire and NYCOCARD$\square$ READERII to quantify hemoglobin A1c. Results: The proportion of well controlled diabetes subjects was 31.3%. When hemoglobin A1c levels became higher, subjects perceived that there were more decay teeth, bleeding, swollen gums, mobility teeth, and oral disease symptoms. In comparison with the well glycemic control group, poor glycemic control group perceived that the overall oral health status was worse, and had more bleeding teeth, swollen gums and mobility teeth. Conclusion: These results show that hemoglobin A1c level is related to the self-reported oral health status. Therefore, dental professionals should emphasize more the necessity of maintaining the hemoglobin A1c of normal range and monitoring it periodically, and the practice of thorough oral hygiene care in order to promote diabetic patients' oral health.

• Journal of Gastric Cancer
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• 제19권3호
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• pp.365-371
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• 2019

The role of surgical intervention in patients with diabetic gastroparesis is unclear. We report a case of a 37-year-old man with a history of recurrent episodes of vomiting and long-standing type 2 diabetes mellitus. Esophagogastroduodenoscopy did not reveal any findings of reflux esophagitis or obstructive lesions. A gastric emptying time scan showed prolonged gastric emptying half-time (344 minutes) indicating delayed gastric emptying. Laboratory tests revealed elevated fasting serum glucose and glycosylated hemoglobin (HbA1c, 12.9%) and normal fasting C-peptide and insulin levels. We performed Roux-en-Y reconstruction after subtotal gastrectomy to treat gastroparesis and improve glycemic control, and the patient showed complete resolution of gastrointestinal symptoms postoperatively. Barium swallow test and gastric emptying time scan performed at follow-up revealed regular progression of barium and normal gastric emptying. Three months postoperatively, his fasting serum glucose level was within normal limits without the administration of insulin or oral antidiabetic drugs with a reduced HbA1c level (6.9%). Long-limb Roux-en-Y reconstruction after subtotal gastrectomy may be useful to treat severe diabetic gastroparesis by improving gastric emptying and glycemic control.

• 한국융합학회논문지
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• 제10권11호
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• pp.501-510
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• 2019

본 논문은 당뇨병의 관리전략 수립을 위해 일상생활에서 조절가능한 혈당조절 요인을 파악하고자 하였다. 개인이 조절하기 어려운 성별, 당뇨병 유병기간, 당뇨병 치료방법, 교육수준, 가구소득 등을 매칭한 코호트내 환자-대조군 디자인으로 분석을 하였다. 7기 국민건강영양조사(2016-2017) 원시자료를 이용하여, 983명의 당뇨병 환자를 분석한 결과, 289명(30%)만이 당화혈색소가 6.5% 미만으로 혈당이 조절되었다. 일상생활에서 조절이 가능한 당화혈색소 조절 요인 파악하기 위해 조건부 다변량 로짓스틱 회귀분석 시행한 결과, 매칭전 코호트에서는 당뇨병 유병기간, 당뇨병 치료 여부, 매칭 코호트에서는 체질량지수, 흡연, 안저검사가 당화혈색소 달성에 유의한 영향을 미치는 것으로 파악되었다. 본 결과는 집중 관리가 필요한 대상선정(장기 유병기간, 약물치료 대상자) 및 생활습관(체질량지수, 흡연, 안저검사 등) 관리전략을 마련하는데 근거자료로 활용되고, 지역사회내 국민건강 증진에 기여할 것으로 사료된다.

• 대한간호학회지
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• 제26권2호
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• pp.413-427
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• 1996

This study was conducted to test the effect of a self regulation education program as a nursing intervention with chronically ill patients. A quasi experimental research(non equivalent control group pretest-posttest design) was used in this study. The subjects were 30 non insulin dependent diabetic patients(experimental group : 14 patients, control group : 16 patients). The study was carried out from May, 1995 to February, 1996. Data were collected before the education program, immediately after ＆ 2 menths later and were analyzed with repeated measure ANCOVA, paired t-test and t-test. The results are as follows : 1. There was a significant difference in self efficacy between the two groups（F＝27.61, P＝0.000）. There was a significant difference according to experimental stages（F＝33.09, P＝0.000） and interaction between education and experimental stages（F＝30.21, P＝0.000）. 2. There was a significant difference in self care behavior between the two groups（F＝27.05, P＝0. 000). There was a significant difference according to experimental stages（F＝31.14, P＝0.000） and interaction between education and experimental stages（F＝28.88, P＝0.000）. 3. There was a significant difference in glycemic control between before the education program and 2 months iater in the experimental group （t＝2.88, P＝0.013）. But there was no significant difference between before the education program and 2 months later in the control group. These results suggest that a self regulation education program is effective in promoting ＆ maintaining self care behavior and in improving glycemic control.. Thus this program can be recommended as an effective nursing intervention for chronically ill patients including diabetic patients.

• 한국식품영양과학회지
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• 제25권4호
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• pp.601-607
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• 1996

Nineteen non-insulin-dependent diabetic(NIDD) and healthy control women were investigated to study the relationship between glycemic control and the level of calcium, zinc, and magnesium in the serum and urine. Urinary calcium, zinc and magnesium levels in the NIDD women were significantly higher(p<0.01) than those of the control women. There were no difference in serum magnesium and zinc levels between the two groups, but se겨m calcium level was lower(p<0.01) in the NIDD women compared to that of the control group. In the NIDD women, serum magnesium was negatively related to fasting blood glucose(r=-0.533 : p<0.05), urinary glucose(r=-0.767 ; P<0.001), urinary protein(r=-0.476 : p<0.05), and urine volume(r=-0.571 : p<0.05). The levels of zinc in both serum (r=0.515, p<0.05) and urine(r=0.623 : p<0.01) were related to urinary protein but only urinary zinc level(r=0.570 : p<0.01) was related to serum albumin. Urinary magnesium, not calcium was correlated with the urinary glucose(r=0.563 : p<0.05) and urinary protein(r=0.568 ; p<0.05). Fasting blood glucose was positively correlated with duration of diabetes, as well as dietary fat and calorie intake. The results of this study suggest that NIDD alters all magnesium, zinc, and calcium utilization, particularly magnesium is involved in glycemic control in this condition.

• Clinical and Experimental Pediatrics
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• 제58권6호
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• pp.234-237
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• 2015

Hepatic glycogenosis in type 1 diabetes mellitus (DM) can be caused by poor glycemic control due to insulin deficiency, excessive insulin treatment for diabetic ketoacidosis, or excessive glucose administration to control hypoglycemia. Mauriac syndrome, which is characterized by hepatomegaly due to hepatic glycogenosis, growth retardation, delayed puberty, and Cushingoid features, is a rare diabetic complication. We report a case of hepatic glycogenosis mimicking Mauriac syndrome. A 14-year-old girl with poorly controlled type 1 DM was admitted to The Catholic University of Korea, Seoul St. Mary's Hospital for abdominal pain and distension. Physical examination revealed hepatomegaly and a Cushingoid face. The growth rate of the patient had decreased, and she had not yet experienced menarche. Laboratory findings revealed elevated liver enzyme levels. A liver biopsy confirmed hepatic glycogenosis. Continuous glucose monitoring showed hyperglycemia after meals and frequent hypoglycemia before meals. To control hyperglycemia, we increased insulin dosage by using an insulin pump. In addition, we prescribed uncooked cornstarch to prevent hypoglycemia. After strict blood glucose control, the patient's liver functions and size normalized. The patient subsequently underwent menarche. Hepatic glycogenosis is a complication of type 1 DM that is reversible with appropriate glycemic control.

• Journal of Nutrition and Health
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• 제40권4호
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• pp.327-333
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• 2007

The present study was carried out to evaluate the physiological effects of mushroom supplementation on blood glucose levels, lipid profile, and antioxidant enzyme activities in subjects with type 2 diabetes mellitus. Subjects were randomized into either a control group or mushroom supplementation group. Mushroom supplementation was provided 3 times a day for 4 weeks. We found that total dietary fiber intake was about 2.5 times higher (30.3 g vs. 12.3 g) in subjects receiving mushroom supplementation than in the control group. Two groups maintained the same food intake and amount of activity, exercise during the supplementation. We observed no difference in age, height, weight, BMI (body mass index), blood pressure between the groups. Nutrient intake did not differ appreciably between the two groups, except for fiber intake, during the supplementation. Fasting blood glucose levels and 2-hour postprandial blood glucose levels were significantly lower in those ingesting mushroom than in controls. Furthermore, the concentrations of low-density lipoprotein cholesterol were decreased significantly in the mushroom supplementation group. Small changes were observed in the concentration of total cholesterol, triglyceride, high-density lipoprotein cholesterol of those supplemented with mushroom, but these changes were not statistically significant. Activities of superoxide dismutase and catalase with mushroom supplementation were higher than in controls, but and glutathione peroxidase activity was not affected. The levels of thiobarbituric acid reactive substance of mushroom group were lower than control group, but were not significant. We conclude that addition of mushroom influences glycemic control and may be effective in lowering blood lipids and improving antioxidant enzyme activities. Accordingly, such effects may reduce risk factors for cardiovascular disease in patients with type 2 diabetes. However, to confirm these effects and to make dietary recommendations for patients with type 2 diabetes, further studies are necessary.

• 한국식품영양학회지
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• 제13권5호
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• pp.419-424
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• 2000

당뇨환자용 빵을 개발하기 위하여 콩가루나 보리가루를 첨가한 롤빵을 제조하여 물성과 관능평가를 분석하고 이들 롤빵을 섭취한 정상인의 혈당반응을 Glycemic Index로 산출하여 혈당조절 효과를 비교하였다. 1. 콩가루 10% 첨가 롤빵의 경도와 탄력성은 밀가루 롤빵과 거의 차이가 없었다. 콩가루나 보리가루의 혼합비율이 클수록(30∼50%) 롤빵의 경도가 증가하였다. 2. 콩가루 10%나 30% 첨가 롤빵은 밀가루 롤빵과 비교하여 색, 풍미, 내부조직, 맛. 조직감, 전체적인 선호도에 있어서 유의차가 없었으며 특히 콩가루 10% 첨가 롤빵은 밀가루 롤빵보다 모든 항목에서 높게 평가되었다. 보리첨가 롤빵은 낮았으나 밀가루 롤빵과 유의차는 없었다. 3. 콩가루 첨가 롤빵은 보리가루 첨가 롤빵이나 밀가루 롤빵보다 섭취 후 혈당상승이 완만하고 GI도 낮았다. 보리가루 50%첨가 롤빵은 밀가루 롤빵과 같이 섭취 직후 혈당이 급속히 상승하였으나 GI는 밀가루 롤빵보다 낮았다. 따라서, 콩가루를 10∼30% 첨가한 롤빵은 밀가루 100%나 보리가루를 첨가한 롤빵에 비하여 기호성이 우수할 뿐만 아니라 혈당조절 효과가 큰 것으로 나타났다.

• 대한한의학회지
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• 제32권5호
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• pp.1-11
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• 2011

Objectives: This study was undertaken to evaluate anti-glycemic and anti-lipid effects of Supungsunkihwan-gagambang, which is composed of Cornus officinalis, Dioscorea Batatas Decaisne, Auantii fructus and Platicodon grandiflorum. Methods: Diabetes was induced in ICR male mice ($24{\pm}1g$) with Surwit's high fat and high sucrose diet. Mice were divided into 3 groups (n=10) of normal, control and Supungsunkihwan-gagambang. The Supungsunkihwan-gagambang group was given 5% herbal medicine in their diet. The animals were fed on each experimental diet for 8 weeks. Body weight was assessed every week. At the 7th week, the fasting blood sugar (FBS) and oral glucose tolerance test (OGTT) were conducted in all experimental groups. After 8 weeks, fructosamine, lipid profile, epididymal fat weight, liver weight and white adipose tissue (WAT) size were measured. Results: Supungsunkihwan-gagambang significantly reduced FBS, OGTT and fructosamine. It also increased high density lipoprotein (HDL) cholesterol and significantly reduced triglyceride/HDL cholesterol ratio, total cholesterol/HDL cholesterol ratio and WAT size. Conclusions: These results show that Supungsunkihwan-gagambang improves anti-glycemic and anti-lipid effect in high fat diet-induced obese mice. Therefore we suggest that Supungsunkihwan-gagambang could be an effective treatment for patients with type 2 diabetes.