Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Correlation among Serum and Urinary Calcium, Zinc, Magnesium and Other Factors in Non-Insulin Dependent Diabetic Women

인슐린 비의존형 당뇨병 여성환자의 혈청과 뇨중 칼슘, 아연 및 마그네슘 함량과 관련인자들과의 상관관계

  • 주은정 (우석대학교 식품영양학과) ;
  • 차연수 (여수수산대학교 식품영양학과) ;
  • 박은숙 (원광대학교 가정교육학과)
  • Published : 1996.08.01
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Abstract

Nineteen non-insulin-dependent diabetic(NIDD) and healthy control women were investigated to study the relationship between glycemic control and the level of calcium, zinc, and magnesium in the serum and urine. Urinary calcium, zinc and magnesium levels in the NIDD women were significantly higher(p<0.01) than those of the control women. There were no difference in serum magnesium and zinc levels between the two groups, but se겨m calcium level was lower(p<0.01) in the NIDD women compared to that of the control group. In the NIDD women, serum magnesium was negatively related to fasting blood glucose(r=-0.533 : p<0.05), urinary glucose(r=-0.767 ; P<0.001), urinary protein(r=-0.476 : p<0.05), and urine volume(r=-0.571 : p<0.05). The levels of zinc in both serum (r=0.515, p<0.05) and urine(r=0.623 : p<0.01) were related to urinary protein but only urinary zinc level(r=0.570 : p<0.01) was related to serum albumin. Urinary magnesium, not calcium was correlated with the urinary glucose(r=0.563 : p<0.05) and urinary protein(r=0.568 ; p<0.05). Fasting blood glucose was positively correlated with duration of diabetes, as well as dietary fat and calorie intake. The results of this study suggest that NIDD alters all magnesium, zinc, and calcium utilization, particularly magnesium is involved in glycemic control in this condition.

Keywords

References

  1. J. Clin. Endocrinol. Metab. v.50 Mineral metabolism in diabetes mellitus : changes accormpanying treatment with a portable subcutaneous insulin infusion system Gertner, J. M.;Tamborlane, W. V.;Horst, R. L.;Sherwin, R. S.;Felig, P.;Genel, M.
  2. J. Trace Elem. Electrolytes Health Dis. v.2 Serum and urinary magnesium, calcium and copper levels in insulin depedent diabetic women Smith, R. G.;Heise, C. C.;King, J. C.;Costa, F. M.;Kitzmiller, J. L.
  3. Eur. J. Clin. Invest v.8 Intestinal and renal handling of calcium in human diabetes mellitus Monnier, L.;Colette, C.;Aguirre, L.;Sony, C.;Mizouze, J.
  4. J. Clin. Eninol. Metab. v.49 Calcium homeostasis in diabetes mellitus Health, H.;Lambert, P. W.;Service, F. J.;Arnaud, S. B.
  5. J. Kor. Diab. Assoc. v.9 Zinc and copper metabolism in diabetes mellitus Kim, S. Y.;Oh, Y. S.;Lee, H. K.;Min, H. K.
  6. J. Kor. Diab. Assoc. v.15 A study on the zinc, copper and chromomium content in serum and 24-hr urine of normal subjects and noninsulin dependent diabetics Park, J. H.;Ro, S. R.;Oh, Y. S.;Christensen, M. S.;Madsbad, S.;Trcnsbal, I.
  7. Clinica. Chimica Acta v.112 Hyperzincuria in insulin treated diabetes mellitus-its relation to glucose homeostasis and insulin adminstration Mcnair, P.;Kiilerich, S.;Christensen, M. S.;Madsbad, S.;Trcnsbal, I.
  8. Diabetes Care. v.11 Hyperzincuria in IDDM women Heise, C. C.;King, J. C.;Costa, F. M.;Kitzmiller, J. L.
  9. Univ. California, Davis, Dept. International Medicine, M. S. Thesis Trace element status and complications of diabetes mellitus Walter, R. M.
  10. Nutr. Res. v.8 Cellular zinc in patients with diabetes mellitus Pai, L. H.;Prasad, A. S.;
  11. Nutr. Res. v.6 Zinc and copper in striated muscle and body fluids from subject with diabetes mellitus type I Sjogren, A.;Edvinsson, L.;Floren, C. H.;Abdulla, M.
  12. Pro. Soci. Exp. Biol. Med. v.180 Influence of spontaneous diabetes on tissue status of zinc, copper and maganese in the BB wistar rat Failla, M. L.;Gardell, C. Y. R.
  13. The Lancet v.28 Magnesium status in diabetes Mather, H. M.;Levin, G. E.
  14. Acta Endocrinologica v.121 Dietary magnesium supplements improve β-cell response to glucose and arginine in elderly non-insulin dependent diabetic subjects Paolisso, G.;Passariello, N.;Pizza, G.;Giunta, R.;Sgambato, S.;Varicchio, M.;D'Onofrio, F.
  15. Am. J. Clin. Nutr. v.56 Influence of dietary protein on a glomerular filteration and urinary albumin excretion in insulin-dependent diabetes Kalk, W. J.;Osler, C.;Contable, J.;Kruger, M.;Panz, V.
  16. Acta. Padiatr. Scand., Suppl v.320 Magnesium metabolism in experimental diabetes mellitus Wibell, L.;Gebre-medhin, M.;Lindmark, G.
  17. Diabetes v.26 Magnesium metabolism in experimental diabetes mellitus Fort, P.;Lifshitz, F.;Wapnir, R. A.
  18. 당뇨병 v.13 당뇨병 환자에서의 마그네슘 농도와 당뇨 조절정도 및 관련 인자들과의 상관관계 한제호;윤건호;강무일;홍관수;차봉연;이광우;손호영;강성구
  19. Brit. Med. J. v.288 Fasting plasma magnesium concentrations and glucose disposal in diabetes Yajnik, C. S.;Smith, R. F.;Hockaday, T. D.;Ward, N. I.
  20. Diabetes v.35 Magnesium defficiency in IDDM related to level of glycosylated hemoglobin Sjogren, A.;Floren, C. H.;Nilsson, A.
  21. Canad. Soc. Clin. Chem. v.21 Urinary albumin excretion in normal subjects and in diabetic measured by a radioimmunoassay : methodological and clinical aspects Giampietro, O.;Miccoli, R.;Clerico, A.;Palma, L. D.;Bertolotto, A.;Anichini, R.;Cristofani, R.;Navalesi, R.
  22. Diabetes v.33 Evidence for a direct action of insulin to increase renal reabsorption of calcium and for an irreversible defect in renal ability to conserve calcium due to prolonged absence of insulin Hoskins, B.;Scott, J. M.
  23. 식품성분표 농촌 진흥청 농촌 영양 개선 연수원
  24. J. Biol. Chem. v.158 On the colorimetric determination of creatinine by the Jaffe reaction Bonsnes, R. W.;Taussky, H. H.
  25. Analy. Biochem. v.72 Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein ; dye binding Bradford, M. A.
  26. 전주 우석대학 논문집 v.14 회화 방법에 따른 뇨중의 칼슘, 마그네슘 및 아연의 함량 비교 연구 주은정
  27. 제2차 호남지역 당뇨병 교육자 세미나 초록집 자가혈당 측정의 지도 정민영
  28. Biochemistry(A case-oriented approach) Montgomery, R.;Dryer, R. L.;Conway, T. W.;Spector, A. A.
  29. 한국영양학회지 v.17 당뇨병 환자의 혈액성분 고찰 및 혈중-Ca농도에 대한 1,25-dihydroxycholecalciferol의 급여 효과 박면애;임숙자;유정렬
  30. 당뇨병 v.12 인슐린 비의존형 당뇨병 환자들의 미세단백뇨(microalbuminuria)측정에서 24시간 소변의 알부민 배출속도, 주간단일 소변에서의 알부민 농도 알부민/크레아티닌 치에 관한 연구 성상규;한경아;권용준;김두만;유형준
  31. Nutr. Rer. v.24 Present knowledge of nutrition in relation to diabetes mellitus Hodges, R. E.
  32. Diet, nutrition and health Carroll, K. K.
  33. J. Clin. Endocrinol. Meta. v.57 Use of oral calcium loading to characterize the hypercalciuria of young insulin dependent diabetics Witt, M. F.;White, N. H.;Santiago, J. V.;Seino, Y.;Avioli, L. V.
  34. Am. J. Physiol. v.244 Zinc, iron and copper absorption in the streptozotocin-diabetic rat Craft, N. E.;Failla, M. L.
  35. 당뇨병 v.15 포도당 자극에 의한 관류 흰쥐 췌장의 인슐린 분비에 대한 칼슘과 마그네슘의 관련성 윤건호;유순집;손현식;강무일;홍관수;차봉연;이광우;손호영;강성구