• Korean Journal of Culture and Social Issue
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• v.28 no.4
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• pp.577-595
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• 2022

The purposes of the study is to classify the psychological characteristics of gamblers using by latent profile analysis and to identify the consequences according toof the latent profiles. The subjects of the study are 473 adults gamblers who responded to a online survey about gambling patterns, basic psychological needs(BPNs), and mental health status(MHS) such as stress, depression, and anxiety. Using latent profile analysis known as the person-centered analysis, the results showed that psychological characteristics of gamblers were classified into three groups: 'Lower MHS-BPNs', 'Middle MHS-BPNs', and 'Upper MHS-BPNs'. Also, the as outcome variable, levels of problematic gambling(KCPGI) showed significant differences across the latent profiles such as Problem gambling(M=11.393) on 'Lower MHS-BPNs', Moderate-risk gambling(M=4.277) on 'Middle MHS-BPNs' and Low-risk gambling (M=1.718) on 'Upper MHS-BPNs'. Overcoming the limitations of variable-centered analysis in the existing studies, this study providesreveals new insights onin the psychological characteristics of gamblers and how different latent profiles of gamblers may be in theirdistinct levels of problematic gambling. Finally, limitations of the study and future directions for research on gambling problems are discussed.

• Journal of Life Science
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• v.33 no.9
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• pp.746-753
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• 2023

Viral infectious diseases have been regarded as one of the greatest threats to global public health. The recent coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a stark reminder of the threat posed by emerging viral infections. Developing and producing appropriate and efficient vaccines and therapeutics are the only options to combat this pandemic. The COVID-19 pandemic has highlighted the need for novel vaccine platforms to control and prevent emerging viral diseases. Conventional vaccine platforms, including live-attenuated vaccine and inactivated vaccines, pose limitations in the speed of vaccine development, manufacturing capacity, and broad protection for emergency use. Interestingly, vaccination with the SARS-CoV-2 vaccine candidate based on the mRNA-lipid nanoparticle (LNP) platform protected against COVID-19, confirming that the nucleoside-modified candidate is a safe and effective alternative to conventional vaccines. Moreover, the prophylactic strategies against the COVID-19 pandemic have been mRNA nucleic acid-based vaccines and nanoparticle-based platforms, which are effective against SARS-CoV-2 and its variants. Overall, the novel vaccine platform has presented advantages compared with the traditional vaccine platform in the COVID-19 pandemic. This review explores the recent advancements in vaccine technologies and platforms, focusing on mRNA vaccines, digital vaccines, and nanoparticles while considering their advantages and possible drawbacks.

• Journal of Digital Convergence
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• v.20 no.3
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• pp.359-366
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• 2022

This study is to provide basic data on intervention methods to enhance the performance of infection control by grasping the relationship between ethical decision-making, moral sensitivity and infection control performance of nursing students in the global COVID-19 pandemic. General characteristics, major-related characteristics, ethical decision-making, moral sensitivity, and infection control were investigated using a structured questionnaires for 3^rd and 4^rd graders of nursing college. To analyze collected data, descriptive statistics, indepentent t-test, one-way ANOVA, Pearson's correlation coefficient, and stepwise multiple regression anlaysis were performed using IBM SPSS21.0 program. As a result of this study, factors influencing the performance of COVID-19 infection control were the principle of beneficence, which is the sub area of ethical decsion-making, and conflict and patient-centered nursing, which is the sub-area of moral sensitivity. In order to improve infection control of nursing students who are prospective medical professionals in a situation where new infectious diseases are highly likely to occur in the future, it is required to develop a practice-oriented convergence education programs for nurses which can improve ethics of patient centered nursing.

• Korea Trade Review
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• v.43 no.1
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• pp.1-23
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• 2018

International Development Cooperation (IDC hereafter), which closely relates to international trade and foreign direct investment, is gaining global importance regarding diplomatic relations and economic cooperation. As Korea contributes increasing resources to the international community, Korea should play a larger role in the IDC along with increasing academic cooperation, impling more necessity to grow research on the IDC as a crucial element of international trade. The IDC has focused on the provision of basic human needs, such as food, shelter, and clothing. However, higher education has not yet be explored for its effectiveness or validity as to service area including foreign trade or insurance. In this regard, this research aims to review existing IDC literature, to propose a project for insurance education, and to provide alternative ways for future development of the IDC. This paper is structured as follows. First, the literature review begins with the IDC's history and development, review of traditional methods of providing basic human needs (food or sheltering) and public health, importance of job creation and business activities to alleviate poverty, and the introduction of insurance education as a vehicle to reduce poverty. Results of the case study provide implications for service area projects including foreign trade education.

• 한국체육학회지인문사회과학편
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• v.57 no.6
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• pp.123-134
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• 2018

The purpose of this study is to analyze the economic efficiency of the policy implemented by Ministry of Culture, Sports and Tourism on leading company in sport industry. The leading companies in sport industry are those who have a certain amount of sales in sport industry and the ones with potential to become global companies. Supporting areas include business advancement, overseas market development, and overseas PR marketing integration support. The research is performed by developing the equilibrium model composed of supply as well as demand and applying input-output analysis. The economic efficiency is estimated to in the form of changes in the sales of corporations and the ripple effect of the national economy. The results of the study are as follows. First, it is estimated that the sales growth rate of the company due to the implementation of the policy is from 3.74% to 5.19%. Second, the increase in sales reaches to a maximum of KRW 4,081 billion with a minimum of KRW 1,573 million, depending on the size of the company. Third, it is estimated that the production inducement effect for the national economy is from KRW 36 billion to KRW 93.4 billion. Fourth, the induced value added for the national economy is estimated to be at least KRW 11.3 billion, up to KRW 29.2 billion.

• Tuberculosis and Respiratory Diseases
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• v.86 no.2
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• pp.142-149
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• 2023

Background: Coronavirus disease 2019 (COVID-19) is an ongoing global public health threat and different variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been identified. This study aimed to analyse the factors associated with negative conversion of polymerase chain reaction (PCR) and prognosis in critically ill patients according to the SARS-CoV-2 variant. Methods: This study retrospectively analysed 259 critically ill patients with COVID-19 who were admitted to the intensive care unit of a tertiary medical center between January 2020 and May 2022. The Charlson comorbidity index (CCI) was used to evaluate comorbidity, and a negative PCR test result within 2 weeks was used to define negative PCR conversion. The cases were divided into the following three variant groups, according to the documented variant of SARS-CoV-2 at the time of diagnosis: non-Delta (January 20, 2020-July 6, 2021), Delta (July 7, 2021- January 1, 2022), and Omicron (January 30, 2022-April 24, 2022). Results: The mean age of the 259 patients was 67.1 years and 93 (35.9%) patients were female. Fifty (19.3%) patients were smokers, and 50 (19.3%) patients were vaccinated. The CCI (hazard ratio [HR], 1.555; p<0.001), vaccination (HR, 0.492; p=0.033), and Delta variant (HR, 2.469; p=0.002) were significant factors for in-hospital mortality. The Delta variant (odds ratio, 0.288; p=0.003) was associated with fewer negative PCR conversion; however, vaccination (p=0.163) and remdesivir (p=0.124) treatments did not. Conclusion: The Delta variant of SARS-CoV-2 is associated with lower survival and negative PCR conversion. Contrary to expectations, vaccination and remdesivir may not affect negative PCR conversion in critically ill patients with COVID-19.

• Journal of Christian Education in Korea
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• v.72
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• pp.273-291
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• 2022

The Industrial Revolution brought great development to the whole human history by the improvement of productive capacity. However, high speed development absorbed just on growth gave rise to resource depletion attack and economical inequality. If it might be neglected human society will meet unsustainable development situation. So UN has made effort to make sustainable development(SD) through global band together. SD concept considers it important to promote current development not giving damage to next generation's development. Then economy, environment and social integration should be harmonized and it demands governance for its actualization. SD gets to be a matter of common interest in education. New Millenium development Goals make African poor countries that are in blind spots of development advance toward gradual sustainable development by supporting programmes to these countries. Thus sustainable development education(SDE) is for future. It has an aim to give suitable education for all people who are all over the world. SDE tries to make health society and successful economical life for all. The concept of SD is found in the essential aims of Christian school and Christian education seeking justice and shalom. Christians are called as transformers for servant mission giving recover in corrupt world. Firstly, Christian school practise this mission making students think on Christian perspectives. Then it makes students serve for environment, economical fairness, social integration with servant mission. Also Christian school has a mission to seek both justice and shalom as a praxis beyond the intellectual dimension of education until fulfilling justice and shalom for all who are all over the world. Thus it can be that Christian school is an important educational institution for realizing sustainable development in that it is always to seek justice and shalom through restoration on the Christian educational perspective.

• Korean Journal of Legislative Studies
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• v.26 no.3
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• pp.125-159
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• 2020

Amid global pandemic of covid-19, Korean government's response has drawn wide attention among social scientists as well as medical studies. The role of Korean state and civil society has attracted particular attention among others. Yet, this paper criticizes extant studies on Korean case which focus on the extensive intervention of the strong state and subjective attitude of Korean citizens in coping with covid-19. The concept of the strong state lacks social scientific specification and subjective citizens do not match with Korean realities. This article argues that Korean state's capacity in collecting and mobilizing digital data may offer better understanding for the successful responses to the pandemic. First, Korean state is the ultimate coordinator in collecting, analyzing and applying big data about the expansion of covid-19 with its huge network of dataveillance. Also, such role has been largely based upon relevant legal framework and well prepared manuals and cooperation with civic actors and companies. In other words, Korean digital dataveillance had demonstrated its transparency and cooperative governance. Second, such dataveillance capacity has deep roots in the long-term development of Korean state's big data management. Korean state has evolved about thirty years while enhancing digital data network within governments, companies and private sectors. Third, the relationship between Korean state's dataveillance and civil society can be characterized as a state centered push model. This model demonstrates highly effective governmental responses to covid-19 crisis but fall short of building social consensus in balancing individual freedom, human rights and effective containment policies. It means communitarian solidarity among citizens has not been a major factor in Korea's successful response yet.

• Journal of Veterinary Science
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• v.24 no.5
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• pp.73.1-73.16
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• 2023

Background: Highly pathogenic avian influenza virus (HPAIV) is considered a global threat to both human health and the poultry industry. MicroRNAs (miRNA) can modulate the immune system by affecting gene expression patterns in HPAIV-infected chickens. Objectives: To gain further insights into the role of miRNAs in immune responses against H5N1 infection, as well as the development of strategies for breeding disease-resistant chickens, we characterized miRNA expression patterns in tracheal tissues from H5N1-infected Ri chickens. Methods: miRNAs expression was analyzed from two H5N1-infected Ri chicken lines using small RNA sequencing. The target genes of differentially expressed (DE) miRNAs were predicted using miRDB. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis were then conducted. Furthermore, using quantitative real-time polymerase chain reaction, we validated the expression levels of DE miRNAs (miR-22-3p, miR-146b-3p, miR27b-3p, miR-128-3p, miR-2188-5p, miR-451, miR-205a, miR-203a, miR-21-3p, and miR-200a3p) from all comparisons and their immune-related target genes. Results: A total of 53 miRNAs were significantly expressed in the infection samples of the resistant compared to the susceptible line. Network analyses between the DE miRNAs and target genes revealed that DE miRNAs may regulate the expression of target genes involved in the transforming growth factor-beta, mitogen-activated protein kinase, and Toll-like receptor signaling pathways, all of which are related to influenza A virus progression. Conclusions: Collectively, our results provided novel insights into the miRNA expression patterns of tracheal tissues from H5N1-infected Ri chickens. More importantly, our findings offer insights into the relationship between miRNA and immune-related target genes and the role of miRNA in HPAIV infections in chickens.

• Smart Media Journal
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• v.12 no.10
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• pp.93-101
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• 2023

Climate change has emerged as a global problem, with frequent temperature increases, droughts, and floods, and it is predicted that it will have a great impact on the characteristics and productivity of crops. Cnidium officinale is used not only as traditionally used herbal medicines, but also as various industrial raw materials such as health functional foods, natural medicines, and living materials, but productivity is decreasing due to threats such as continuous crop damage and climate change. Therefore, this paper proposes a model that can predict the physiologically active ingredient index according to the climate change scenario of Cnidium officinale, a representative medicinal crop vulnerable to climate change. In this paper, data was first augmented using the CTGAN algorithm to solve the problem of data imbalance in the collection of environment information, physiological reactions, and physiological active ingredient information. Column Shape and Column Pair Trends were used to measure augmented data quality, and overall quality of 88% was achieved on average. In addition, five models RF, SVR, XGBoost, AdaBoost, and LightBGM were used to predict phenol and flavonoid content by dividing them into ground and underground using augmented data. As a result of model evaluation, the XGBoost model showed the best performance in predicting the physiological active ingredients of the sacrum, and it was confirmed to be about twice as accurate as the SVR model.