• 현장농수산연구지
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• 제23권1호
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• pp.31-36
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• 2021

고 문헌에 기록된 부자의 가공수치 포제법으로 숙부자로 가공하고 인삼, 생강, 감초의 배합으로 폐암세포와 대식세포 독성에 관하여 실험한 결과 1번째 실험군 인삼과 숙부자 처리군에서 100 ㎍/ml 농도에서 독성에 영향을 주기 시작하여 1000 ㎍/ml 농도에서 더 많은 영향을 주었다. 그 중 대식세포 보다는 A549 폐암세포에서 더 많은 세포독성에 영향을 주었다. 그리고 2번째 실험군에 추가로 생강이 배합된 처리군에서는 1000 ㎍/ml 농도부터 세포독성이 시작 되었으며 대식세포 보다는 A549 폐암세포에 세포독성에 더 많은 영향을 주었으며 마지막 3번째 실험군 생강과 감초가 추가된 실험군에서는 100 ㎍/ml 농도에서 A549 폐암세포에 독성이 시작 되었지만 대식세포에는 영향이 없었으며, 1000 ㎍/ml 농도부터 대식세포와 A549 폐암세포에 영향을 주었다. 결론적으로 독성이 강한 부자를 사용함에 있어서는 반드시 숙부자로 가공하여 활용 하여야 하며 인삼, 생강, 감초의 배합으로 정상세포인 대식세포 독성에는 적은 영향과 특정 폐암세포가 더 많은 세포독성이 있음을 확인할 수 있었다. 앞으로도 인삼, 생강, 감초의 복합추출물이 지속적인 연구를 통해 항암활성의 효능을 검증하고 추가적인 연구가 필요할 것이라 사료된다.

• 한국식품조리과학회지
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• 제17권5호
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• pp.490-496
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• 2001

본 연구는 돼지고기 조리시에 향신료와 한약재를 부재료로 첨가하여 편육을 조리했을 때, 부재료가 편육의 품질특성에 미치는 영향을 조사하였다. 돼지고기에 대조구는 물만 첨가하였고, 편육 A는 물과 간장, 편육 B는 A에 양파, 생강을, 편육 C는 B에 감초, 계피를, D는 C에 정향, 율피를 첨가하여 편육의 부재료(향신료와 한약재) 종류를 다르게 첨가한 5종류의 편육을 제조하여 실험한 결과는 다음과 같다. 1. 등심과 사태 편육의 일반성분을 분석한 결과, 조단백질과 회분은 시료간에 유의적인 차이가 없었으나, 감초와 계피를 첨가한 편육 C와 정향, 율피를 첨가한 편육 D는 조지방의 함량이 타 시료에 비하여 유의적으로 낮았다(p＜0.05). 2. 편육의 색도에서 명도(L)는 대조구에 비하여 부재료의 종류가 많이 첨가될수록 낮은 값을 보인 반면에(p＜0.05), 적색도 a값은 부재료가 많이 첨가될수록 증가 되었다. 3. 부재료를 첨가한 편육의 기계적 특성중 경도는 대조구에 비하여 부재료를 첨가한 A, B, C, D가 유의적으로 낮았으며(p＜0.05) 응집성과 점착성은 대조구와 A, B, C, D간에 유의적 차이는 나타나지 않았다. 4. 부재료의 첨가에 따른 편육의 관능검사 결과, 향, 맛, 경도, 응집성, 탄력성, 점착성은 대조구가 가장 낮았고, D가 가장 높았으며, 시료간 유의적 차이를 나타내었다(p＜0.05). 전체적인 기호도는 대조구와 A, B, C보다 D를 가장 선호하는 것으로 나타났다(p＜0.05). 5. 기계적 경도는 관능적 향, 맛, 응집성, 점착성, 부서짐성 및 종합적 기호도와 부적 상관관계가 있는 것으로 나타났으며, 관능적 특성에 있어서 색은 기계적 탄력성, 점착성 및 부서짐성과 부적상관관계를 나타내었다. 이상의 결과에서 돼지고기 편육 조리시에 감초, 계피, 정향, 율피 등의 부재료를 첨가함으로써 육류의 지방성분을 감소시킬 수 있으며, 아울러 고기를 연화시키고 편육의 향과 맛을 좋게하여 품질을 개선하는 효과가 있는 것으로 판단된다.

• 대한한의학회지
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• 제16권1호통권29호
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• pp.451-467
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• 1995

In order to study on Bu-ja(Oh-du) toxicosis, the outhor investigated many documents. The results obtained were as follows: 1. Toxicosis of Bu-ja(Oh-du) arised mainly from carelessness in use. 2. In the symptoms of Bu-ja(Oh-du), Heart System(心系) symptom often came out. 3. The general and local paralysis, falling of blood pressure in Heart System(心系) symptom : vertigo, cramp in Liver System(肝系) symptom : nausea, vomiting in Spleen System (脾系) symptom : difficulty of breathing in Lung System(肺系) symptom : wasting disease in Kidney System (腎系) symptom frequently originated from toxicosis of Bu-ja(Oh-du). 4. In the detoification method, there are atropin injection, carrying out a gastric lavage, and supplying a liquid medicine from the western medicine : taking ginger-licorice root decoction, taking mung beans thick decoction and getting vomited with soaked cinnamon from the oriental medicine. And also keeping warm and oxygen inhalation were used to counteract poison. 5. A pregnant woman, heat of excess type(實熱), yang sydrome(陽證 )must not be taken Bu-ja(Oh-du).

• 한국수산과학회지
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• 제44권2호
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• pp.141-148
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• 2011

This feeding experiment was conducted to investigate the effects of dietary inclusion of various additives on growth performance, hematological parameters, fatty acid composition, gene expression and histopathological changes in juvenile olive flounder (Paralichthys olivaceus). Eleven isonitrogenous (49% crude protein) and isolipidic (10% crude lipid) experimental diets were formulated: no additives (Con); 5% kelp meal (Ke); 10% krill meal (Kr); 1% garlic powder (Ga); 1% citrus meal (Ci); 3% onion powder (On); 1% ginger powder (Gi); 1% mugwort powder (Mu); 1% licorice powder (Li); 1% wasabi powder (Wa); and a mixture (Mix) of these additives. Three replicate groups of juvenile flounder (average weight of 8.5 g) were fed one of the experimental diets to visual satiety twice a day for 15 weeks. The dietary inclusion of additives did not affect survival, weight gain, specific growth rate feed efficiency, daily feed intake, daily protein intake, protein efficiency ratio, hepatosomatic index and visceralsomatic index of the fish. Plasma triglyceride levels were significantly lower in fish fed the Ke, Ga, On, Gi, Mu, Li, and Mix diets than in fish fed the control diet. Plasma glucose, glutamic oxaloacetic transaminase and total cholesterol did not differ among dietary treatments. No significant difference was observed in fatty acid composition and lipid content of the dorsal muscle in fish fed the experimental diets. Myosin gene expression did not differ significantly among treatments after 5 weeks but was significantly lower in fish fed the Kr, Ci, Li, and Mix diets than in control group after 15 weeks. Histopathological analysis showed mild gill hyperplasia and mild necrosis of liver parenchymal cells in several individuals of each experimental group. These conditions were also observed in the control group and were not thought to be related to the inclusion of feed additives. The present findings indicate that the dietary inclusion of additives did not affect growth performance, fatty acid composition, gene expression, and histopathological changes in juvenile flounder. However, plasma triglyceride content may be reduced by supplementation with 5% kelp meal, 3% onion powder, 1% garlic powder, 1% ginger powder, 1% mugwort powder, and the additive mixture.

• 대한예방한의학회지
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• 제22권1호
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• pp.81-90
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• 2018

Objectives : The aim of this study is to analyze the patent trend in Traditional Korean Tea. In this paper, we investigate the diversity of Korean Tea registered as patents focusing on the kinds of medicinal herbs used, processing methods, and types of tea. Methods : We collected patents data using KIPRIS, and WIPS database. We conducted Quantitative Analysis by year and main patentee, and Qualitative Analysis by patent's contents. Results : 313 patents are selected from 2001 to May 2017. The number of patents have been on the rise and reached 44 in 2014. Individuals have registered the most patents, followed by companies, Industry-University Cooperation Foundation, and local autonomous entities. Ginger, Omija and Cactus were used at high frequency among 109 tea containing one medicinal herb. Licorice and Jujube were frequently used among 204 tea containing more than two kinds of medicinal herbs. In classification of patent by efficacy, 'health promotion and function recovery' and 'treatment and prevention of diseases' are most frequently specified. 128 patents are presenting processing methods for medicinal herbs in the order of roasting, fermentation, and fumigation. Among 164 patents presenting tea types, liquid type accounts for more than half and there are 67 leached tea, and 32 powder tea. Conclusion : The analyses results showed that lots of new recipes, efficacy, processing methods and tea types are being studied and registered as patents. In order to help Traditional Korean Tea industry to develop, active patent registration and further study about up-to-date patent trend would be required.

• Preventive Nutrition and Food Science
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• 제16권4호
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• pp.333-338
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• 2011

In this study, antioxidative and anti-inflammatory activities of the herb (cinnamon, clove, glehnia root, ginger, violet-root cromwell, licorice, citrus peel and longan) extracts used for gamhongroju, one of the popular liqueurs in Korea, were investigated. Twenty grams of individual herbs were extracted in 60% purified ethanol and freeze-dried. A mixture of the individual herb extracts (HEM) was separately prepared. Cytotoxicity of the individual extracts and HEM on murine RAW264.7 macrophage cells were examined along with their recovering activity on $H_2O_2$-treated RAW264.7 cells. Antioxidant and anti-inflammatory activities of the extract-treated cells were determined by measuring superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities, and Trolox equivalent antioxidant capacity (TEAC), nitric oxide (NO) and prostaglandin E2 (PGE2) levels. Violet-root cromwell extract showed the least cytotoxicity in terms of treated concentration. Most of the extracts, below levels of cytotoxicity, recovered the $H_2O_2$-treated cells. Treatment with some of the extracts increased SOD and GPx activities and TEAC levels while a majority inhibited the production of NO and PGE2 in lipopolysaccharide (LPS)-treated cells.

• 대한한의학방제학회지
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• 제22권1호
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• pp.65-78
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• 2014

Objectives : The purpose of this study was to investigate the interpretation of the Ondam-tang(Ondam-tang, here-in-after referred to as "ODT") prescription in order to obtain the evidence for clinical applications. Methods : We have analyzed the interpretation on the ODT prescription through translations and comparisons based on classic books about the oriental medical prescriptions. Result : 1. ODT was first mentioned in the Jiyangfang(集驗方) which was quoted in the Waitaimiyao (外臺秘要). After that, in book Sanyinjiyibingzhengfanglun(三因極一病證方論), Chen-yan(陳言) completed and recorded in a book organizing prescriptions of ODT now in frequent use. 2. The Banha(半夏) removes the dam(痰-phlegm) and relieves emesis. The Jinpee(陳皮) encourages strengths, and the Bokryoung composes oneself and produces the water. The Licorice(甘草) relieves people's mind, and the Ginger relieves gastrointestinal problems and relieves emesis. Juk-yeo(竹茹) abate of the fever of the Sangcho(上焦). Jisil(枳實) encourages strength, controlling Samcho(三焦) as releasing the congestion of energy. In these ways, numerous symptoms resulted from the imbalances of the Gallbladder(膽) are treated. 3. Meaning of "on(溫-warm)" in ODT regains the original characteristic of the Gallbladder(膽). 4. Treatment mechanism of ODT is 'cooling the Gallbladder(膽)' and 'remedies Samcho(三焦)' and 'eliminates dam(痰)' and 'cure Kiwool(氣鬱-which is kind of depressions) and Saengyen(生涎-which is kind of phlegm)' and 'removes a mismatch between Gallbladder(膽) and Stomache(胃)'. Conclusion : In this study, we have demonstrated various methodologies. This paper will be useful to the future researchers and clinicians to conduct a study on herbal medicines such as the ODT.

• 대한한의학방제학회지
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• 제12권1호
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• pp.79-92
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• 2004

This thesis aims to provide an analytical basis for existing or new prescriptions based on the theory for properties and tastes of Korean oriental herbal medicines. To this end, prescriptions presented in the Various Changes in the Dominations of the Six Energies and their Relations with the Diseases of Plain Questions were analyzed based on the theory for properties and tastes of Korean oriental herbal medicines in Yellow Emperor's Canon of Internal Medicine. This thesis focused on symptoms and prescriptions based on the theory for properties and tastes of Korean oriental herbal medicines, which were described in tire Various Changes in tire Dominations of tire Six Energies and their Relations with the Diseases of Plain Questions with regard to the year when Taeeum is affecting the earth energy and the dampness energy is partially over-abundant. Those symptoms and prescriptions originate from the theory of the five elements and six climates. The symptoms were analyzed from the perspective of physiology. The prescriptions were first analyzed based on the theory for properties and tastes of Korean oriental herbal medicines in Yellow Emperor's Canon of Internal Medicine. Then, a mix formula of oriental medicines pursuant to those prescriptions was studied. Lastly, established prescriptions, which were in conformity with the above prescriptions, were selected. From the physiological point of view, symptoms with regard to the year when Taeeum is affecting the earth energy and the dampness energy is partially over-abundant can be, based on the theory of the five elements and six climates, diagnosed as the symptoms from impaired kidney due to excessive dampness energy. Established prescriptions pursuant to prescriptions based on the theory for properties and tastes of Korean oriental herbal medicines can be broken down into the following: Poria powder with five herbs (Oryeongsan); Divine black bird decoction (Jinmootang); Tetrandra and astragalus decoction (Banggihoanggitang); Licorice, dried ginger, poria and bighead atractylodes decoction (Gamgangryeongchooltang); Spleen-reinforcing powder (Shilbeesan). Therefore, symptoms of six kinds of weather presented in the Various Changes in the Dominations of tire Six Energies and their Relations with tire Diseases of Plain Questions can be analyzed from the physiological point of view. As a result, in addition to the methodology that analyzes existing prescriptions within the boundary of the theory for properties and tastes of Korean oriental herbal medicines in Yellow Emperor's Canon of Internal Medicine, it is expected that a theoretical basis for new prescriptions can be provided by analyzing established prescriptions based on prescriptions from the theory for properties and tastes of Korean oriental herbal medicines.

• 한국식품영양학회지
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• 제17권1호
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• pp.18-24
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• 2004

천연 식물류 추출물을 첨가하여 제조한 약주의 영양성분과 항산화 활성을 비교 분석한 결과 수용성 페놀화합물은 천연식물 첨가 약주에서 대조군(5.5 mg/kg)에 비하여 약 1.7배 더 높게 정량 되었으며, 잔존율도 47.4%로 더 높았다. 유리당은 대조군에서는 arabinose와 maltose가 각각 16.2, 15.6 mg/100 g 검출된 반면, 천연식물을 첨가한 약주에서는 lactose가 6.9 mg/100 g으로 가장 높은 함량이었고 maltose는 검출되지 않았다. 무기물의 함량은 인> 칼륨 > 마그네슘 >칼슘 >철분의 순으로 높게 검출되었고, 철분과 나트륨은 숙성 기간의 경과에 따른 함량 차이가 거의 없었다. 아미노산 함량은 숙성 기간의 경과와 더불어 감소하였는데 대조군의 경우 숙성 30일에 총 아미노산 함량이 약 72% 감소한 반면 천연식물을 첨가한 약주의 경우 약 6.8%로 감소 비율이 훨씬 낮았다. 약주를 각기 다른 농도로 희석하여 전자공여능을 측정한 결과 대조군의 경우 희석배수가 증가할수록, 숙성기간이 경과할수록 전자공여능이 저하되는 경향을 나타내었다. 반면 천연식물류를 첨가한 약주는 숙성 30일까지 희석 배수에 관계없이 95.7∼96.7%의 높은 전자공여능을 나타내었다. SOD 유사활성은 희석배수 및 숙성기간의 경과와 서로 반비례하는 경향을 나타내었다. 가장 높은 SOB 유사활성을 나타낸 숙성 3일째의 천연식물류 첨가 약주의 경우 원액과 2배 희석한 시료에서 각각 51.5, 53.9%의 SOD 유사활성을 나타내었다.

• 한국식품저장유통학회지
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• 제18권6호
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• pp.907-915
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• 2011

전주지역의 모주는 막걸리에 인삼, 칡, 감초, 계피, 대추, 생강 등 생약재와 흑설탕을 넣고 일정시간 교반 가열한 후 여과해서 만드는 해장술 개념의 저농도 알코올성 음료이다. 기호성이 높은 모주 개발을 위한 정보를 제공할 목적으로, 전주 시내의 음식점에서 판매되는 전주모주 22종의 이화학적, 관능적 특성을 평가하였다. 이화학적 분석치의 평균값은 수분 91.28%, 알코올 1.09%, pH 4.25, 총산 0.27%, 환원당 40.68 mg/mL, 당도 13.75 $^{\circ}Bx$, 점도 11.19 cP이었다. 유기산 중 lactic acid, malic acid, citric acid 함량이 다른 3종의 유기산에 비해 높게 나타났으며, 유리당 중 sucrose 함량이 glucose, fructose 함량보다 월등히 높게 나타났다. 유리아미노산 함량은 175.3 mg%로 모주의 주원료인 탁주에 비해 적은 편으로 이는 모주 제조과정 중에 가열에 따른 갈변반응의 기질로서 탁주의 유리아미노산이 이용되었기 때문으로 사료된다. 관능검사 결과, 전체적인 기호도가 비교적 높은 모주는 총산 함량이 0.15~0.25%로 낮을 뿐만 아니라, 당도는 10.6~13.4 $^{\circ}Bx$, 점도는 5.73~9.57 cP 범위의 모주이었다.