• International Journal of Advanced Culture Technology
• /
• v.3 no.1
• /
• pp.101-112
• /
• 2015

Renewable energy resources play an important part in the world's future. Renewable energy sources have the following components: biomass, geothermal, solar thermal, directs solar, wind, tidal and hydropower. Hydropower is still the most efficient way to generate electricity worldwide. Hydropower projects can contribute as a cheap energy source, as well to encourage the development of small industries across a wide range of new technology; furthermore hydropower systems use the energy in flowing and falling water to produce electricity or mechanical energy. Hydropower systems are classified as large, medium, small, mini and micro according to their installed power generation capacity, as do the following components: water turbines, control mechanisms and electrical transmissions. In this article a review of small hydropower systems has been done on the principles surrounding the fundamentals of hydraulic engineering, the fundamentals of hydrology, identification of sites and economic analysis.

• Molecules and Cells
• /
• v.20 no.2
• /
• pp.256-262
• /
• 2005

The neuronal cytoskeleton is essential for establishment of neuronal polarity, but mechanisms controlling generation of polarity in the cytoskeleton are poorly understood. The nonreceptor tyrosine kinase, Fer, has been shown to bind to microtubules and to interact with several actin-regulatory proteins. Furthermore, Fer binds p120 catenin and has been shown to regulate cadherin function by modulating cadherin-${\beta}$-catenin interaction. Here we show involvement of Fer in neuronal polarization and neurite development. Fer is concentrated in growth cones together with cadherin, ${\beta}$-catenin, and cortactin in stage 2 hippocampal neurons. Inhibition of Fer-p120 catenin interaction with a cell-permeable inhibitory peptide (FerP) increases neurite branching. In addition, the peptide significantly delays conversion of one of several dendrites into an axon in early stage hippocampal neurons. FerP-treated growth cones also exhibit modified localization of the microtubule and actin cytoskeleton. Together, this indicates that the Fer-p120 interaction is required for normal neuronal polarization and neurite development.

• Environmental Analysis Health and Toxicology
• /
• v.18 no.3
• /
• pp.165-174
• /
• 2003

Cr (Ⅵ) - containing compounds are well-established carcinogens, although the mechanism for chromium - induced carcinogenesis is still not well understood. The reduction of Cr (Ⅵ) to its lower oxidation states, par ticularly Cr (V) and Cr (IV), is an important step for the production of chromium-mediated reactive oxygen species (ROS). The persistent oxidative stress during the reduction process may play a key role in the mechanism of Cr (Ⅵ) -induced carcinogenesis. This paper summarizes recent studies on (1) the reduction of Cr (Ⅵ) to Cr (III) occur by a multiplicity of mechanisms depending on the nature of reducing agents including ascorbate, diol-and thiol-containing molecules, certain flavoenzymes, cell organelles, intact cells, and whole animals; (2) free-radical production with emphasis on hydroxy radical generation via Fenton or Haber-Weiss type reactions; and (3) free radical - induced cellular damage, such at DNA strand breaks, hydroxylation of 2'-deoxyguanosine, and activation of nuclear transcription factor kB.

• Proceedings of the KIEE Conference
• /
• 2004.11c
• /
• pp.663-665
• /
• 2004

Ethernet-based passive optical network(EPON) technology is being considered as a promising solution for next-generation broadband access network. It must have the property of high efficiency, low cost, and support quality of service(QoS). A major feature for this new architecture is the use of a shared transmission media between all connected optical network unit(ONU). Hence, medium access control(MAC) arbitration mechanisms are essential for the successful implementation of EPON. In this paper we propose a simple dynamic bandwidth allocation(DBA) algorithm that improves the performance of network and supports IP-based multimedia applications with the bursty data traffic. In addition, we introduce analytic models of proposed algorithms and prove the system based on our algorithm to be asymptotically stable. Simulation results show the new DBA algorithm provides high bandwidth efficiency and low queueing delay of ONU in EPON.

• The Academic Congress of Korean Shoulder and Elbow Society
• /
• 2002.10a
• /
• pp.7-7
• /
• 2002

Historically, the decision to perform a hemiarthroplasty (HHR) versus a total shoulder arthroplasty (TSA) is based on the status of the glenoid and the status of the soft tissues (rotator cuff). In disease processes where the glenoid articular cartilage is relatively well preserved such as avascular necrosis and complex proximal humerus fractures, most orthopaedists recommend performing a HHR while preserving the native glenoid articular surface. At the other end of the spectrum, if the glenoid has excessive bone loss or is unreconstructible, a HHR is the preferred procedure. In patients who have deficient so(t-tissues (rotator cuff) such as rotator cuff tear arthropathy and, occasionally, rheumatoid arthritis, a HHR is the procedure of choice. The indications for HHR in osteoarthritis remain somewhat controversial. There is mounting evidence that performing a HHR for osteoarthritis is inferior to TSA. Recent developments, or 'third generation techniques and materials', in shoulder arthroplasty are expected to improve the longevity of TSA, particularly the glenoid component. In addition, newer designs of reverse-ball prostheses are entering the market with promising early results in patients with deficient rotator cuff mechanisms.

• Journal of the Korean Ceramic Society
• /
• v.54 no.6
• /
• pp.449-469
• /
• 2017

The development of quantum dots (QDs) has had a significant impact on various applications, such as solar cells, field-effect transistors, and light-emitting diodes (LEDs). Through successful engineering of the core/shell heterostructure of QDs, their photoluminescence (PL) quantum yield (QY) and stability have been dramatically enhanced. Such high-quality QDs have been regarded as key fluorescent materials in realizing next-generation display devices. Particularly, electrically driven (or electroluminescent, EL) QD light-emitting diodes (QLED) have been highlighted as an alternative to organic light-emitting diodes (OLED), mostly owing to their unbeatably high color purity. Structural optimizations in QD material as well as QLED architecture have led to substantial improvements of device performance, especially during the past decade. In this review article, we discuss QDs with various semiconductor compositions and describe the mechanisms behind the operation of QDs and QLEDs and the primary strategies for improving their PL and EL performances.

• BMB Reports
• /
• v.57 no.3
• /
• pp.135-142
• /
• 2024

DNA methylation is one of the most extensively studied epigenetic regulatory mechanisms, known to play crucial roles in various organisms. It has been implicated in the regulation of gene expression and chromatin changes, ranging from global alterations during cell state transitions to locus-specific modifications. 5-hydroxymethylcytosine (5hmC) is produced by a major oxidation, from 5-methylcytosine (5mC), catalyzed by the ten-eleven translocation (TET) enzymes, and is gradually being recognized for its significant role in genome regulation. With the development of state-of-the-art experimental techniques, it has become possible to detect and distinguish 5mC and 5hmC at base resolution. Various techniques have evolved, encompassing chemical and enzymatic approaches, as well as third-generation sequencing techniques. These advancements have paved the way for a thorough exploration of the role of 5hmC across a diverse array of cell types, from embryonic stem cells (ESCs) to various differentiated cells. This review aims to comprehensively report on recent techniques and discuss the emerging roles of 5hmC.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.24 no.1 s.173
• /
• pp.225-231
• /
• 2000

Dimensional synthesis of planar and spatial mechanisms mostly requires solution-finding, procedure for a system of polynomial equations. In case the system is nonlinear, numerical techniques like Newton-Raphson are often used. But there are no logical ways for finding all possible solutions in such iterative methods. In this paper, algebraic elimination is used to get all solutions for the synthesis of 5-SS spatial mechanism with seven prescribed positions. The proposed algorithm is more suitable for computer implementation and takes less time than existing one. Two numerical examples are given to demonstrate the implemented algorithm.

• Archives of Pharmacal Research
• /
• v.26 no.3
• /
• pp.183-191
• /
• 2003

Nucleic acid therapies represent a direct genetic approach for cancer treatment. Such an approach takes advantage of mechanisms that activate genes known to confer a growth advantage to neoplastic cells. The ability to block the expression of these genes allows exploration of normal growth regulation. Progress in antisense technology has been rapid, and the traditional antisense inhibition of gene expression is now viewed on a genomic scale. This global view has led to a new vision in antisense technology, the elimination of nonspecific and undesirable side effects, and ultimately, the generation of more effective and less toxic nucleic acid medicines. Several antisense oligonucleotides are in clinical trials, are well tolerated, and are potentially active therapeutically. Antisense oligonucleotides are promising molecular medicines for treating human cancer in the near future.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.25 no.8
• /
• pp.1053-1059
• /
• 2001

Results from direct numerical simulation and LDV measurements are analyzed to investigate the influence of structured surface on turbulence in the outer layer. To provide a well-defined surface roughness, sinusoidal wavy surface was used. Even though flows over smooth and wavy surface show very different process for maintaining turbulence in the vicinity of the wall, there are some evidences that the turbulence in the outer layer has a universal characteristics and it may be possible to give a speculative interpretation that similarity of turbulent structures arises because Reynolds stress producing motion is similar regardless of different turbulence generation mechanisms embedded in both cases.