• 제목/요약/키워드: General assessment category

검색결과 44건 처리시간 0.026초

The Polymerase Chain Reaction in Diagnosis of Small B-Cell Non-Hodgkin Lymphomas

  • Antoro, Ester Lianawati;Dwianingsih, Ery Kus;Indrawati, Indrawati;Triningsih, FX Ediati;Harijadi, Harijadi
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.491-495
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    • 2016
  • Background: Small B-cell non-Hodgkins lymphoma (NHL) is difficult to be distinguished from non-neoplastic reactive processes using conventional haematoxylin-eosin (HE) staining due to different interpretations among pathologists with diagnosis based on morphologic features. Ancillary examinations such as immunohistochemical (IHC) staining are essential. However, negative or doubtful results are still sometimes obtained due to unsatisfactory tissue processing or IHC technique. The polymerase chain reaction (PCR) as a molecular diagnostic technique is very sensitive and specific. Clonality detection of heavy chain immunoglobulin (IgH) gene rearrangement has been widely used to establish diagnosis of B-cell NHL. Aims: To elaborate interobserver variation in small B-cell NHL diagnosis based on morphologic features only and to confirm sensitivity and specificity of the PCR technique as an ancillary method. Materials and Methods: A toptal of 28 samples of small B cell NHL and suspicious lymphoma were interpreted by 3 pathologists in Sardjito General Hospital based on their morphology only. The reliability of assessment and the coefficient of interobserver agreement were calculated by Fleiss kappa statistics. Interpretation results were confirmed with IHC staining (CD20, CD3, Bcl2). PCR was performed to analyze the clonality of IgH gene rearrangement. Results: Interobserver agreement in morphologic evalution of small B cell NHL and chronic lymphadenitis revealed kappa coefficient 0.69 included in the substantial agreement category. The cases were divided into 3 groups based on morphology and IHC results; lymphoma, reactive process and undetermined group. PCR analysis showed 90% sensitivity and 60% specificity. Conclusions: The present study revealed a substantial agreement among pathologists in small B-cell NHL diagnosis. For difficult cases, PCR is useful as complementary method to morphologic and IHC examinations to establish definitive diagnosis.

탄성파시험의 이동성 확보를 위한 마이크로폰 센서의 활용 (Utilization of a Microphone to Acquire Mobility in Seismic Testing)

  • 조성호;부카리;노리나
    • 대한토목학회논문집
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    • 제33권4호
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    • pp.1509-1521
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    • 2013
  • 구조물의 안정성에 대한 사회적 요구는 이를 충족시키기 위한 기술발전으로 이어지게 되었고, 지각구조를 이해하기 위해 개발된 탄성파기법도 구조물의 건전성을 평가하는 비파괴 기법으로 자리매김하게 되었다. 비파괴 탄성파기법의 핵심은 측정대상 매질의 탄성파 속도를 측정하는 것으로, 탄성파의 전파를 측정하는 센서를 필수적으로 사용하여야 한다. 기존의 탄성파기법은 접촉식 센서를 사용하기 때문에 이동중 연속시험이 불가능한 문제점이 있었고, 탄성파 시험의 효율성이 실용적 요구조건에 부합하지 못하는 한계성이 있었다. 본 연구에서는 비접촉식 센서의 일종인 보급형 마이크로폰을 센서로 활용하여 기존 탄성파 시험의 문제점을 극복하고자 하는 연구를 수행하였다. 다짐지반의 실시간 다짐품질 확인, 콘크리트 구조물의 재료강성 및 내부결함의 확인 등을 위한 표면파 시험과 공진시험 등을 마이크로폰 활용대상으로 설정하였고, 마이크로폰센서의 영향인자 연구, 실구조물에 대한 현장시험 등을 수행하였다. 이를 통하여 마이크로폰 센서의 신뢰성과 효율성을 확인할 수 있었으며, 최적의 마이크로폰 활용방안을 제안하였다.

주요 치료재료 품목군의 건강보험청구액 결정요인분석 (Analysis on the Determinants of Therapeutic Materials Expenditure in National Health Insurance)

  • 변진옥;이주향;김유리;이혜재
    • 보건행정학회지
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    • 제26권4호
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    • pp.333-342
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    • 2016
  • Background: The use of therapeutic materials based on new health technology has increased in recent years in the field of medicine, raising concerns for medical practitioners regarding increased spending on the new therapeutic materials amid the rapid population ageing and increase of chronic diseases in Korea. While therapeutic materials have significant importance in the health care system, they have not been given appropriate attention in the academic world of Korea. The purpose of this study is to identify factors that affect the growth of expenditure on therapeutic materials and to derive implications for an effective management considering the diversity of therapeutic materials. Methods: Using the claims data of the National Health Insurance Services, specific utilization patterns of groups of therapeutic materials in the middle classification level of Health Insurance Review and Assessment Service from 2007 to 2014 were analyzed. Four categories (J5083: drug eluting coronary stent, D0302: nonmetallic anchor, K6014: gauze, K6023: gauze) that exhibit unique patterns with respect to price and volume were selected. Then, decomposition analysis was performed to identify the largest contributor to the spending growth by dividing the products into existing, new, and abandoned products for the period between 2010 and 2013. Results: The effect of new products had larger impact on spending growth than the effect of core items in drug eluting coronary stent (J5083) and nonmetallic anchor (D0302). In addition, existing products in general included items priced relatively lower when compared with another item manufactured by the same company. In the gauze category, however, existing products had the largest impact on expenditure and the effect of volume was greater than that in other categories. Conclusion: This study provides evidence that appropriate management measures classified by the characteristics of therapeutic materials are required for therapeutic materials pricing and reassessment in Korea.

MEASURING THE INFLUENCE OF TASK COMPLEXITY ON HUMAN ERROR PROBABILITY: AN EMPIRICAL EVALUATION

  • Podofillini, Luca;Park, Jinkyun;Dang, Vinh N.
    • Nuclear Engineering and Technology
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    • 제45권2호
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    • pp.151-164
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    • 2013
  • A key input for the assessment of Human Error Probabilities (HEPs) with Human Reliability Analysis (HRA) methods is the evaluation of the factors influencing the human performance (often referred to as Performance Shaping Factors, PSFs). In general, the definition of these factors and the supporting guidance are such that their evaluation involves significant subjectivity. This affects the repeatability of HRA results as well as the collection of HRA data for model construction and verification. In this context, the present paper considers the TAsk COMplexity (TACOM) measure, developed by one of the authors to quantify the complexity of procedure-guided tasks (by the operating crew of nuclear power plants in emergency situations), and evaluates its use to represent (objectively and quantitatively) task complexity issues relevant to HRA methods. In particular, TACOM scores are calculated for five Human Failure Events (HFEs) for which empirical evidence on the HEPs (albeit with large uncertainty) and influencing factors are available - from the International HRA Empirical Study. The empirical evaluation has shown promising results. The TACOM score increases as the empirical HEP of the selected HFEs increases. Except for one case, TACOM scores are well distinguished if related to different difficulty categories (e.g., "easy" vs. "somewhat difficult"), while values corresponding to tasks within the same category are very close. Despite some important limitations related to the small number of HFEs investigated and the large uncertainty in their HEPs, this paper presents one of few attempts to empirically study the effect of a performance shaping factor on the human error probability. This type of study is important to enhance the empirical basis of HRA methods, to make sure that 1) the definitions of the PSFs cover the influences important for HRA (i.e., influencing the error probability), and 2) the quantitative relationships among PSFs and error probability are adequately represented.

A Comparative Study on Clinical Gait Abilities of Stroke Patients According to Indoor and Outdoor Environments

  • Hwang, Hyesun;Woo, Youngkeun;Chung, Yijung
    • Physical Therapy Rehabilitation Science
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    • 제10권3호
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    • pp.356-366
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    • 2021
  • Objective: This study aimed to compare gait ability through gait evaluations in indoor and outdoor environments according to the general characteristics and walking ability of stroke patients. Design: Crossed-sectional study. Methods: The subjects of this study were 57 hospitalized stroke patients.The study subjects were asked to select an indoor environment and an outdoor environment in random order, and the Timed Up and Go Test (TUG), 10-Meter Walk Test (10MWT), Figure-Eight Walk Test (F8WT) and the Functional Gait Assessment (FGA) were used to assess each environment. Results: The TUG, 10MWT, F8WT time and number of steps, and FGA showed a significant decrease in gait ability in the outdoor environment compared to the indoor environment (p<0.05). Although the TUG, 10MWT, and the time required for the F8WT were statistically higher in the outdoor compared to the indoor environment at points 2, 3, and 4, but not 5 of the functional ambulatory category (FAC), significant increases in the number of steps of the F8WT were found in the outdoor compared to the indoor environment for only points 2 and 3 of the FAC (p<0.05). In the FAC 3 and 4, there was a statistically significant decrease in the outdoor compared to the indoor environment only in the FGA (p<0.05). Conclusions: Therefore, it has been shown that the gait ability of stroke patients is reduced in the outdoor environment compared to the gait ability in the indoor environment.

Problems of Using Cyberdramaturgy in Modern Foreign Cinematography

  • Portnova, Tatiana V.
    • International Journal of Computer Science & Network Security
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    • 제22권10호
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    • pp.25-30
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    • 2022
  • The article is devoted to the actual problem of the use of digital technologies in modern cinema in developed countries. The purpose of the study is to identify the essence of the term "cyberdramaturgy" and the problems of its use in modern film production. The research methodology is based on a systematic approach and includes the methods of the general scientific group (analysis, synthesis, deduction, induction), as well as a number of special methods: the method of content analysis of scientific literature on the research topic; sociological survey method; as well as the method of statistical analysis. The results of the survey were analyzed using the Neural Designer program (a tool for advanced statistical analytics) and translated into a graphical diagram format for clarity of perception. Answers in 75 questionnaires were evaluated by the average score for six analysis criteria, which made it possible to bring all the calculations to a 10-point scale. As a result of the study, the author of the article concluded the following: directors believe that the use of cyber analogues of actors and backgrounds leads to the blurring of genres, the hybridization of cinema and animation; directors are also concerned about the problem of replacing the director himself with a special program. The writers are completely concerned with the problem of machine scripting with almost infinite variability beyond the human imagination. Directors-producers believe that the cyberdramaturgy development will lead to completely new standards of cinematic quality, sharply different from the traditional assessment of acting and scene setting, to the appreciation of 3D animation as the highest category in the art. Such innovations actually devalue all international cinematography awards, as cyberdrama reduces the value of cyberactors to zero. It is impossible to bail out an "Oscar" or a "Golden Globe" award for a digital double or a separate cyber model that is used in the film instead of the actors.

ADS-33 평가기준에 따른 소방헬기 비행시뮬레이터의 비행조종성 예비평가 (Preliminary Evaluation of Handling Qualities of a SAR(Search & Rescue) Helicopter Simulator Based on ADS-33 Requirements)

  • 윤석준;김동현;성은혜;박태준;황호연;안존;이정훈
    • 한국항공우주학회지
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    • 제44권9호
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    • pp.796-805
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    • 2016
  • 본 연구는 헬리콥터 비행 시뮬레이터 개발의 첫 번째 단계의 일환으로 비행 운동 모델의 비행조종성을 해석적으로 평가한다. 비행 운동 모델은 시뮬레이터의 목표 항공기인 AS365 N2의 공개 정보를 사용하여 생성하였다. 해당 비행 시뮬레이터는 소방 임무에 대한 조종사 교육 및 연구 도구로 개발 중이다. 모델의 평가는 비행 시험 데이터를 통한 검증이 이루어지기 전에 모델의 비행 특성과 다음 개발 단계로의 적합성을 평가하기 위하여 수행된다. 평가는 항공기분류, 임무 및 환경을 고려하여 ADS-33E-PRF(Aeroautical Design Standard Performance Specification Handling Qualities Requirement)의 기준에 의거하여 수행한다. 항공기의 해석적 비행은 규정에 대한 적합성 평가를 위해 요구되는 혹은 권장되는 비행시험절차를 따른다. 평가 결과는 ADS-33E-PRF에 명시된 조종성 등급에 따라 평가되는데 RotorLibFDM을 기반으로 생성된 비행 운동 모델이 헬기 비행에 대한 기본 교육과 연구로 사용될 수 있는 일반적인 헬리콥터 시뮬레이터에 대한 만족스러운 플랫폼을 제공함이 확인되었다.

기타가공품의 중금속, 부정유해물질 모니터링 및 노출량 평가 (Other Processed Products, Monitoring and the Exposed Dose Assessment of Heavy Metal, the Illegal Compounds)

  • 장진섭;권문주;김명희;박진수;임수선;권성희;송성민;여은영;홍성희;김정임;엄애선
    • 한국식품위생안전성학회지
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    • 제30권1호
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    • pp.35-42
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    • 2015
  • 본 연구는 인천광역시내 유통되고 있는 기타가공품에 대하여 중금속 (납, 카드뮴, 수은), 부정유해물질 (발기부전치료제와 그 유사물질 36종, 비만치료제 3종, 스테로이드 28종)을 조사하여 안전성을 평가하고, 기타가공품에 대한 기준규격 제정 시 기초자료로서 제공하고자 실시하였다. 그결과 부정유해물질은 검출되지 않았고, 중금속은 납(Pb) 0.001~13.39(mg/kg), 카드뮴(Cd) 0.003~1.231(mg/kg), 수은(Hg)은 0.001~0.650(mg/kg)의 결과를 얻었다. 기타가공품은 중금속에 대한 규격 기준이 없으므로, 중금속의 국내 외 기준을 비교하였을 때 중금속 최고기준을 적용하면 납(Pb)과 수은(Hg)에서 각각 2건씩 4건이 초과되는 것으로 확인되었다. 검사결과를 바탕으로 한 중금속의 위해성 평가는 FAO/WHO (Codex)의 잠정주간섭취허용량(PTWI)과 비교결과, 해물파전믹스, 들깨가루는 Pb의 PTWI의 기준 0.214를 초과하였다. 결론적으로 분말류나 환제품을 유사식품 기준으로 적용하면 부적합으로 판정 될 수 있기 때문에 규격검사를 피할 목적으로 기타가공품으로의 등록을 지향한다. 이를 악용할 경우 검사의 사각지대로 인해 시민의 건강이 위협받을 수 있다. 따라서 품목제조허가 신고시 규격외 일반가공식품에서 기타가공품으로의 등록을 지양하고, 기타가공품의 세부적인 검사규격을 제정하여 관리해야 함을 제언한다.

설비공학 분야의 최근 연구 동향 : 2013년 학회지 논문에 대한 종합적 고찰 (Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2013)

  • 이대영;김사량;김현정;김동선;박준석;임병찬
    • 설비공학논문집
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    • 제26권12호
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    • pp.605-619
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    • 2014
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2013. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. Conclusions are as follows. (1) The research works on the thermal and fluid engineering have been reviewed as groups of fluid machinery, pipes and relative parts including orifices, dampers and ducts, fuel cells and power plants, cooling and air-conditioning, heat and mass transfer, two phase flow, and the flow around buildings and structures. Research issues dealing with home appliances, flows around buildings, nuclear power plant, and manufacturing processes are newly added in thermal and fluid engineering research area. (2) Research works on heat transfer area have been reviewed in the categories of heat transfer characteristics, pool boiling and condensing heat transfer and industrial heat exchangers. Researches on heat transfer characteristics included the results for general analytical model for desiccant wheels, the effects of water absorption on the thermal conductivity of insulation materials, thermal properties of Octadecane/xGnP shape-stabilized phase change materials and $CO_2$ and $CO_2$-Hydrate mixture, effect of ground source heat pump system, the heat flux meter location for the performance test of a refrigerator vacuum insulation panel, a parallel flow evaporator for a heat pump dryer, the condensation risk assessment of vacuum multi-layer glass and triple glass, optimization of a forced convection type PCM refrigeration module, surface temperature sensor using fluorescent nanoporous thin film. In the area of pool boiling and condensing heat transfer, researches on ammonia inside horizontal smooth small tube, R1234yf on various enhanced surfaces, HFC32/HFC152a on a plain surface, spray cooling up to critical heat flux on a low-fin enhanced surface were actively carried out. In the area of industrial heat exchangers, researches on a fin tube type adsorber, the mass-transfer kinetics of a fin-tube-type adsorption bed, fin-and-tube heat exchangers having sine wave fins and oval tubes, louvered fin heat exchanger were performed. (3) In the field of refrigeration, studies are categorized into three groups namely refrigeration cycle, refrigerant and modeling and control. In the category of refrigeration cycle, studies were focused on the enhancement or optimization of experimental or commercial systems including a R410a VRF(Various Refrigerant Flow) heat pump, a R134a 2-stage screw heat pump and a R134a double-heat source automotive air-conditioner system. In the category of refrigerant, studies were carried out for the application of alternative refrigerants or refrigeration technologies including $CO_2$ water heaters, a R1234yf automotive air-conditioner, a R436b water cooler and a thermoelectric refrigerator. In the category of modeling and control, theoretical and experimental studies were carried out to predict the performance of various thermal and control systems including the long-term energy analysis of a geo-thermal heat pump system coupled to cast-in-place energy piles, the dynamic simulation of a water heater-coupled hybrid heat pump and the numerical simulation of an integral optimum regulating controller for a system heat pump. (4) In building mechanical system research fields, twenty one studies were conducted to achieve effective design of the mechanical systems, and also to maximize the energy efficiency of buildings. The topics of the studies included heating and cooling, HVAC system, ventilation, and renewable energies in the buildings. Proposed designs, performance tests using numerical methods and experiments provide useful information and key data which can improve the energy efficiency of the buildings. (5) The field of architectural environment is mostly focused on indoor environment and building energy. The main researches of indoor environment are related to infiltration, ventilation, leak flow and airtightness performance in residential building. The subjects of building energy are worked on energy saving, operation method and optimum operation of building energy systems. The remained studies are related to the special facility such as cleanroom, internet data center and biosafety laboratory. water supply and drain system, defining standard input variables of BIM (Building Information Modeling) for facility management system, estimating capability and providing operation guidelines of subway station as shelter for refuge and evaluation of pollutant emissions from furniture-like products.

상급종합병원 비급여 진료비 변이에 따른 항목 표준화에 관한 연구 (A Study of Category Standardization according to Non-benefit Medical Expense in Tertiary Hospitals)

  • 노옥희;안상윤;김용하;이종형;박아르마;김광환
    • 한국산학기술학회논문지
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    • 제21권5호
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    • pp.274-280
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    • 2020
  • 이 연구의 목적은 건강보험심사평가원에서 공개한 2015년 4월부터 2018년 4월까지 상급종합병원의 비급여 진료비 자료를 사용하여 비급여 진료비 항목별로 현황 및 평균 비용과 변이가 있는지 파악하는 것이다. 조사대상은 2015년, 2016년, 2017년, 2018년 4월 기준 상급종합병원 44개 기관 중 취소되거나 신규로 지정된 기관은 제외하고 최종 41개 상급종합병원의 비급여 진료비 현황이다. 연구방법은 건강보험심사평가원 정보공개창구에서 공개 자료를 요청한 후 승인을 받아 진행하였다. 분석방법은 일반적 특성과 연도별 비급여 항목 현황은 빈도분석, 연도별 변이 파악은 변동계수(C.V.)를 선정하여 분석하였다. 연구 결과, 비급여 진료비 세부항목의 현황을 비교 분석한 결과 비급여 항목의 개수가 2015년에는 총 51개였지만, 2016년 53개, 2017년, 98개로 점점 증가 추세를 보였으며 2018년에는 총 193개 항목으로 급격히 증가하였다. 상급종합병원 비급여 진료비 변이에 따른 항목 표준화를 위해서 정부는 비급여 진료비 표준화를 확대하고 의료기관은 표준화된 비급여 진료비 항목이나 명칭 등을 사용하도록 의무화하여야 한다.