• Title/Summary/Keyword: Gender Sensitivity

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Expression of DOG1, CD117 and PDGFRA in Gastrointestinal Stromal Tumors and Correlations with Clinicopathology

  • Sun, Xiu-Wei;Feng, Zhan-Jun;Huang, Peng;Hao, Wang;Sui, Xing-Ling
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1389-1393
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    • 2012
  • Objective: To discuss the significance of DOG1, CD117 and PDGFRA in the diagnosis of gastrointestinal stromal tumors (GISTs), and analyze their correlations with clinicopathological features and risk ranking. Method: DOG1, CD117 and PDGFRA were detected with IHC Envision ldpe-g-nvp in 63 GISTs and 43 cases of non-GISTs, and analyzed for relations with clinicopathological factors (gender, age, location, tumor size, mitotic phase, histology) and risk degree. Results: The positive expression rate of DOG1, CD117 and PDGFRA in GISTs was 84.1% (53/63), 90.5% (57/63), 53.2% (33/63), respectively. Among the 6 CD117 negative cases, all were DOG1 positive and 5 were PDGFRA positive. Rates in patients with non-GISTs was 11.6%, 16.3%, 6.98%, respectively. Expression of DOG1 and PDGFRA demonstrated no significant variation with gender, age, position, tumor size, mitotic phase, histology, and risk rank. However, CD117 was related with position and histology (P=0.008 and P=0.045), those in the mesentery having a higher positive rate than those derived from stomach, small intestine, colon and rectum (50.0% vs 94.7%, P=0.008). Furthermore CD117 was also highly expressed in spindle and epithele types. Conclusions: DOG1 had a good sensitivity and specificity as a kind of newly discovered marker, especially for KIT negative GISTs. However, DOG1, CD117 and PDGFRA cannot be used for assessing the rish of patients.

A Trend Analysis of Floral Products and Services Using Big Data of Social Networking Services

  • Park, Sin Young;Oh, Wook
    • Journal of People, Plants, and Environment
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    • v.22 no.5
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    • pp.455-466
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    • 2019
  • This study was carried out to analyze trends in floral products and services through the big data analysis of various social networking services (SNSs) and then to provide objective marketing directions for the floricultural industry. To analyze the big data of SNSs, we used four analytical methods: Cotton Trend (Social Matrix), Naver Big Data Lab, Instagram Big Data Analysis, and YouTube Big Data Analysis. The results of the big data analysis showed that SNS users paid positive attention to flower one-day classes that can satisfy their needs for direct experiences. Consumers of floral products and services had their favorite designs in mind and purchased floral products very actively. The demand for flower items such as bouquets, wreaths, flower baskets, large bouquets, orchids, flower boxes, wedding bouquets, and potted plants was very high, and cut flowers such as roses, tulips, and freesia were most popular as of June 1, 2019. By gender of consumers, females (68%) purchased more flower products through SNSs than males (32%). Consumers preferred mobile devices (90%) for online access compared to personal computers (PCs; 10%) and frequently searched flower-related words from February to May for the past three years from 2016 to 2018. In the aspect of design, they preferred natural style to formal style. In conclusion, future marketing activities in the floricultural industry need to be focused on social networks based on the results of big data analysis of popular SNSs. Florists need to provide consumers with the floricultural products and services that meet the trends and to blend them with their own sensitivity. It is also needed to select SNS media suitable for each gender and age group and to apply effective marketing methods to each target.

The Effect of Self-leadership and Rejection Sensitivity on Subjective Quality of Life in College Students (전문대학생의 셀프리더십, 거부민감성이 주관적 삶의 질에 미치는 영향)

  • Lee, Yunju;Seo, Bomi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.9
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    • pp.156-165
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    • 2018
  • The purpose of this study was to provide a basic data required to improve the satisfaction of life in college students. A sample of 607 students attending the university in Incheon, Korea completed a survey, which consisted of a quality of life questionnaire and sociodemographic inventory. The data were collected between November 14 and November 30, 2016. Data analysis was performed using t-test, ANOVA, Pearson correlation coefficients, and stepwise multiple regression analysis with SPSS/WIN 18.0 program. The subjective quality of life was significantly correlated with self-leadership (r=.279, p<0.01) and rejection sensitivity (r=-.224, p<0.01). The significant predictors that influence the quality of life of subjects were satisfaction in major, natural reward strategies, gender, anticipated anxiety and grade, in which 27.6% (F=47.27, p<0.01) was the explained variance. (Ed note: confirm) This study showed that rejection sensitivity and self-leadership were significant factors that influenced college students' subjective quality of life. Therefore, college administrators may consider developing educational programs about rejection sensitivity and self-leadership for college students to improve subjective quality of life.

Searching for a Curriculum to Reconceptualize Sexuality for Youth Sex Education : Nth Room Era, New Talk of 'Body' and 'Sex' from a Feminist Theological Point of View (청소년 성교육을 위한 성성(性性)의 재개념화 커리큘럼 모색 : N번방 시대, 여성신학적 관점에서 '몸'과 '성'을 새롭게 이야기하다)

  • Lee, Jooah
    • Journal of Christian Education in Korea
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    • v.67
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    • pp.301-337
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    • 2021
  • The researcher looked at the differences in views and various controversies surrounding Korean youth sexuality education in the wake of the Nth Room incident, which had a great impact on modern Korean society. Sex education for adolescents in Korea can be divided into public sex education through school sex education and the Youth Sexuality Center, and conservative/traditional Protestant sex education. Public sex education is partly influenced by feminist sexual ethics and comprehensive sex education abroad. Based on gender sensitivity and the right to sexual self-determination, four major projects are prevention of sexual harassment, prostitution, sexual violence, and domestic violence. However, the school sex education standard was criticized for stereotypes of gender roles and gender-discriminatory content, reinforced distorted myths about sexual violence, and exclusion of sexual diversity and various family types. Conservative/traditional Protestantism is based on the normal family ideology such as bisexual marriage, premarital chastity, and sexual ethics recognized only within marital relationships. It is a form of confrontation with public sex education while strongly opposing it. The researcher first analyzed the characteristics of public sex education, conservative/traditional Protestant sexual ethics and sex education, feminist sex ethics and sex education, and overseas youth sex education, respectively, while composing the curriculum for Korean youth sexuality education. And as a more fundamental solution to youth sexuality education, I pointed out that there are limits to asceticism, premarital chastity, gender sensitivity and sexual self-determination education, and found an alternative to the concept of body and sex in feminist theology. The researcher pointed out that it is necessary to reconceptualize the body and sex under the recognition that the most fundamental cause of distorted sexual culture is dualistic sex and understanding the body, centering on the research of various feminist theologians. And this was conceptualized into three concepts: holistic sexuality, mutual solidarity understood in relationships with others, and sexuality as a spirituality that extends to the global community. And with each curriculum, 1) Holistic Sexuality: Breathing, Narrative, Making the Shape of One's Body and Mind 2) mutual solidarity : Feeling the Breath of Others, Media Literacy through Conscientization, Sending a Good Wind 3) Sexuality as a spirituality that extends to global concern: It was proposed to pay attention to nature and to co-cultivate it, to listen to the earth's moans and create a new way of life, and to write a prayer with the earth and fellow living beings.

F-Wave Analysis in Patients with Clinically Diagnosed Carpal Tunnel Syndrome (임상적으로 진단된 수근관증후군 환자에서 F파 분석)

  • Kim, Seong-Hee;Yoo, Bong-Goo;Kim, Kwangsoo;Yoo, Kyung-Moo
    • Annals of Clinical Neurophysiology
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    • v.4 no.2
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    • pp.108-113
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    • 2002
  • Background and Objective : Carpal tunnel syndrome (CTS) is the most common mononeuropathy encountered in clinical practice. No single procedure or group of procedures has demonstrated adequate sensitivity. F-wave study in CTS is very rarely reported. To determine the diagnostic usefulness of new parameters of F-wave and comparative study of F-wave parameters of median and ulnar nerves in patients with CTS. Methods : F-wave responses of median and ulnar nerves were analyzed from 27 patients with clinically diagnosed CTS and 22 age and gender-matched normal control. Conventional F-wave parameters were studied. Also, the usefulness of new parameters such as mean and maximal ulnar-median F-wave latency differences, ulnar-median F-wave persistence and chronodispersion differences, median/ulnar F-wave amplitude ratio, and F-wave conduction velocity (FCV) using mean and maximal latency were assessed. Results : Compared with controls, median F-wave minimal, maximal and mean latencies, mean F-wave amplitude/M-wave amplitude, minimal, mean and maximal ulnar-median F-wave latency differences, and FCVs using minimal, maximal and mean latency were significant (P<0.05~0.001). Median F-wave minimal, maximal and mean latencies, mean ulnar-median F-wave latency difference, and FCVs using minimal, maximal and mean latency showed high sensitivity and specificity. Mean ulnar-median F-wave latency difference and FCVs using maximal and mean latency were new parameters. Conclusion : New F-wave parameter including mean ulnar- median F-wave latency difference and FCVs using maximal and mean latency may be a useful to assess the CTS. Also, median F-wave minimal, maximal and mean latencies, and FCV using minimal latency may be included in routine diagnostic tests in CTS.

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Accuracy of Live Fluoroscopy to Detect Intravascular Injection During Lumbar Transforaminal Epidural Injections

  • Lee, Min-Hye;Yang, Kyung-Seung;Kim, Young-Hoon;Jung, Hyun-Do;Lim, Su-Jin;Moon, Dong-Eon
    • The Korean Journal of Pain
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    • v.23 no.1
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    • pp.18-23
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    • 2010
  • Background: Complications following lumbar transforaminal epidural injection are frequently related to inadvertent vascular injection of corticosteroids. Several methods have been proposed to reduce the risk of vascular injection. The generally accepted technique during epidural steroid injection is intermittent fluoroscopy. In fact, this technique may miss vascular uptake due to rapid washout. Because of the fleeting appearance of vascular contrast patterns, live fluoroscopy is recommended during contrast injection. However, when vascular contrast patterns are overlapped by expected epidural patterns, it is hard to distinguish them even on live fluoroscopy. Methods: During 87 lumbar transforaminal epidural injections, dynamic contrast flows were observed under live fluoroscopy with using digital subtraction enhancement. Two dynamic fluoroscopy fluoroscopic images were saved from each injection. These injections were performed by five physicians with experience independently. Accuracy of live fluoroscopy was determined by comparing the interpretation of the digital subtraction fluoroscopic images. Results: Using digital subtraction guidance with contrast confirmation, the twenty cases of intravascular injection were found (the rate of incidence was 23%). There was no significant difference in incidence of intravascular injections based either on gender or diagnosis. Only five cases of intravascular injections were predicted with either flash or aspiration of blood (sensitivity = 25%). Under live fluoroscopic guidance with contrast confirmation to predict intravascular injection, twelve cases were predicted (sensitivity = 60%). Conclusions: This finding demonstrate that digital subtraction fluoroscopic imaging is superior to blood aspiration or live fluoroscopy in detecting intravascular injections with lumbar transforaminal epidural injection.

Post-pandemic influenza A (H1N1) virus detection by real-time PCR and virus isolation

  • Zaki, Ali Mohamed;Taha, Shereen El-Sayed;Shady, Nancy Mohamed Abu;Abdel-Rehim, Asmaa Saber;Mohammed, Hedya Said
    • Korean Journal of Microbiology
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    • v.55 no.1
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    • pp.25-32
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    • 2019
  • Influenza A (H1N1) virus caused a worldwide pandemic in 2009-2010 and still remains in seasonal circulation. Continuous surveillance activities are encouraged in the post pandemic phase to watch over the trend of occurrence every year, this is better to be done by a rapid and sensitive method for its detection. This study was conducted to detect proportions of occurrence of influenza A virus (H1N1) in patients with influenza-like illness. Samples from 500 patients with influenza or influenza-like clinical presentation were tested by real-time reverse transcription polymerase chain reaction (RT-PCR) and virus tissue culture. Among the total 500 participants, 193 (38.6%) were females and 307 (61.4%) males. Seventy-one patients (14.2%) were positive for H1N1 virus infection with real-time RT-PCR while 52 (10.4%) were positive by tissue culture. Non-statistically significant relation was found between age and gender with the positivity of H1N1. Sensitivity and specificity of real-time RT-PCR was 98.08% and 95.54%, respectively, in comparison to virus isolation with accuracy 95.8%. This study showed that H1N1 virus was responsible for a good proportion of influenza during the post-pandemic period. Real-time RT-PCR provides rapidity and sensitivity for the detection of influenza A virus (H1N1) compared with virus isolation and thus it is recommended as a diagnostic tool.

A Comparative Study of Predictive Factors for Passing the National Physical Therapy Examination using Logistic Regression Analysis and Decision Tree Analysis

  • Kim, So Hyun;Cho, Sung Hyoun
    • Physical Therapy Rehabilitation Science
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    • v.11 no.3
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    • pp.285-295
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    • 2022
  • Objective: The purpose of this study is to use logistic regression and decision tree analysis to identify the factors that affect the success or failurein the national physical therapy examination; and to build and compare predictive models. Design: Secondary data analysis study Methods: We analyzed 76,727 subjects from the physical therapy national examination data provided by the Korea Health Personnel Licensing Examination Institute. The target variable was pass or fail, and the input variables were gender, age, graduation status, and examination area. Frequency analysis, chi-square test, binary logistic regression, and decision tree analysis were performed on the data. Results: In the logistic regression analysis, subjects in their 20s (Odds ratio, OR=1, reference), expected to graduate (OR=13.616, p<0.001) and from the examination area of Jeju-do (OR=3.135, p<0.001), had a high probability of passing. In the decision tree, the predictive factors for passing result had the greatest influence in the order of graduation status (x2=12366.843, p<0.001) and examination area (x2=312.446, p<0.001). Logistic regression analysis showed a specificity of 39.6% and sensitivity of 95.5%; while decision tree analysis showed a specificity of 45.8% and sensitivity of 94.7%. In classification accuracy, logistic regression and decision tree analysis showed 87.6% and 88.0% prediction, respectively. Conclusions: Both logistic regression and decision tree analysis were adequate to explain the predictive model. Additionally, whether actual test takers passed the national physical therapy examination could be determined, by applying the constructed prediction model and prediction rate.

The Correlation Between Smartphone Addiction and Sensory Processing Feature Depending on Gender in College Students (작업치료전공 대학생의 성별에 따른 스마트폰 중독과 감각처리와의 관련성)

  • Hong, Eunkyoung;Lee, Hyerim
    • The Journal of Korean Academy of Sensory Integration
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    • v.16 no.3
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    • pp.1-10
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    • 2018
  • Objective : The purpose of this study was to investigate smartphone addition and sensory processing character depend on gender for occupational therapy (OT) students, and to identify the correlation between smartphone addiction and sensory processing feature. Methods : Participants of this study were 168 (70 male/90 female) students majoring occupational therapy. Measurements in this study were a questionnaire about general information of subject, smartphone addiction scale, and adult/adolescent sensory profile. Data collection period was from November 2017 to March 2018. Methods for the data analysis included descriptive statistics, independent t-test and Pearson correlation of SPSS 22.0. Results : In term of the purpose of using smartphone, majority response was communication and gaming ranked in next. There were difference between male and female in the total smartphone addition, cyberspace-oriented relationship, withdrawal and tolerance. The result showed that all sensory processing are related with total smartphone addition (r = .236 ~ .603) for man. And for women, total smartphone addition is little related with the taste/smell processing (r= .290), visual processing (r= .324), touch processing (r= .214), low registration (r= .214), sensory sensitivity (r= .243), and sensory avoiding (r= .217). Conclusion : This study found that there is difference between male and female in terms of relation between smartphone addition and sensory processing feature according for occupational therapy students.

Relationship between Carotid Intima Media Thickness and Appendicular Skeletal Muscle Index according to Gender (성별에 따른 경동맥 내중막두께와 사지근육량지수와의 관련성)

  • Yang, Sung-Hee;Lee, Hee-Jeong
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.309-317
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    • 2022
  • It is reported that social distancing caused by the corona pandemic has resulted in a decrease in physical activity, and a decrease in muscle mass due to this increases the risk of vascular disease. Therefore, in this study, the risk of carotid intima media thickness was evaluated by measuring the thickness of CIMT, and the differences in variables according to gender were analyzed. From January 2022 to May 2022, a total of 220 people (121 males, 99 females) who performed blood tests, carotid ultrasound, and body composition analysis among those who visited the health check-up center of Busan H Hospital were included in this study. Significant differences in risk factors according to gender were analyzed using the chi-square test. The cut-off values of variables that can predict the risk of carotid intima media thickness were calculated, and the accuracy was evaluated by calculating the area under the curve, sensitivity, and specificity. As a result of the difference analysis, the higher the total cholesterol in men and the appendicular skeletal muscle index in women, the higher the risk of carotid intima media thickness. The cut-off value for predicting the risk of carotid intima media thickness was calculated to be greater than 199 mg/dL of total cholesterol in the male group and less than 5.9 kg/m2 of the appendicular skeletal muscle index in the female group. As a result of this study, the higher the total cholesterol in men and the lower the appendicular skeletal muscle index in women, the higher the risk of increased CIMT. Therefore, in women, the appendicular skeletal muscle index is expected to serve as an indicator to predict and prevent vascular changes at an early stage.