• 제목/요약/키워드: Gall stone

검색결과 24건 처리시간 0.03초

소아 담석증에 대한 임상적 연구 (A Clinical Study for Gall Bladder Stones in Children)

  • 은호선;백승연;정기섭
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제8권2호
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    • pp.194-201
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    • 2005
  • 목 적: 소아에서 담석증은 성인에 비해 드문 질환이며, 여아에서 호발하고, 전형적인 증상은 드물 어서 나이가 어릴수록 무증상일 가능성이 높다. 원인으로 구상적혈구증, 복부 수술, 항생제(ceftriaxone), 감염 등에 의하여 유발되기도 하며, 유전 요인, 환경적 요인 등에 의해서도 영향을 받는 것으로 알려져 있다. 그러나 현재 우리나라에서 소아의 담석증에 대한 연구 보고는 드물다. 이에 저자들은 연세의대 소아과에 내원하여 담석증으로 진단 받은 환아들을 대상으로 임상적 특성을 알아보고자 본 연구를 시행하였다. 방 법: 1999년 1월 1일부터 2005년 5월 31일까지 본 병원 소아과에 내원하여 담석증으로 진단 받은 15세 이하의 환아 총 18예를 대상으로 조사 분석하였다. 대상 환아는 복부 초음파 검사 또는 복부 CT 검사에서 담석증으로 확진된 경우만으로 하였고, 이러한 영상검사를 시행하지 않았거나 담낭잔사를 보인 환아는 대상에서 제외하였다. 결 과: 대상 환아는 남아 12예, 여아 6예로 남녀 비는 2:1이었고, 연령별 분포는 최소 4개월부터 최대 13년 3개월 된 환아까지 다양하였다. 전체 평균은 $6{\pm}4.3$세였고, 남아는 $6.1{\pm}3.9$세, 여아는 $5.8{\pm}5.6$세로 큰 차이는 없었다. 담석증에 의한 증상은 18예 중 3예(16.7%)에서 고열, 복통, 구토 등이 있었고, 나머지 15예(83.3%)에서는 증상이 없었다. 이러한 증상은 남녀간에 차이가 없었고, 연령이 많을수록 나타나는 경향을 보였다. 총 18예 중 15예(83.3%)에서 유발 요인이 있었는데, 항생제(ceftriaxone) 투여가 6예(33.3%), 감염이 4예(22.2%), 구상적혈구증이 3예(16.7%), Down 증후군과 복부 수술이 1예(5.6%)에서 각각 있었다. 담석의 크기는 17예 중 15예(88.2%)가 5 mm 이하의 담석으로 가장 많았고, 다음으로 5~10 mm가 2예(11.8%)였고, 10mm 이상은 없었다. 담석의 수는 단발(single)과 다발(multiple)이 각각 14예(77.8%), 4예(22.2%)로 단발성 담석이 많았다. 말초혈액도말 검사상 백혈구증다증, 고콜레스테롤 혈증, 고칼슘 혈증을 보인 환아는 없었으나, 2예에서 철결핍성 빈혈이 있었다. 혈청 AST 및 ALT는 7예(58.3%)에서 증가되었는데, 이 중 전염성 단핵구증에 감염된 환아는 2예로 이 중 1예는 혈청 빌리루빈치가 약간 상승되어 있었고, 마이코플라즈마에 감염된 1예는 급성 췌장염이 합병되어 혈청 amylase 및 lipase가 상승되어 있었으며, 1예는 캔디다 감염이 동반되어 있었다. 치료는 18예 중 17예(94.4%)에서 보존적 치료를 하였으며 주기적으로 복부 초음파를 시행하면서 추적 관찰하였다. 수술은 Meckel 게실이 동반되었던 1예에서 담낭 적출술을 시행하였다. 추적 관찰하였던 환아 17예 중 13예에서 복부 초음파상 담석이 소실되었고, 3예는 추적 관찰 중이며, 나머지 1예는 추적 관찰에서 탈락되었다. 탈락된 1예를 제외한 17예 모든 환아에서 재발이나 합병증은 없었다. 결 론: 본 연구 결과 소아 담석증은 남아에서 호발하고, 어릴수록 무증상이 많다. 유발요인이 있는 환아가 많았고, 크기가 작은 단일석이 대부분이었다. 치료는 대부분 보존적 치료를 하였다. 최근 영상진단의학이 발달함에 따라 소아에서도 담석증의 발견율이 높아지고 있다. 그러나 우리나라에서 소아 담석증에 대한 연구보고는 드물다. 따라서 소아 담석증 환아에서 성인과 다른 특성과 또한 유발 요인 등을 비롯한 외국 환아와의 임상적 차이점 등을 알아보기 위하여 이에 대한 연구가 더 필요할 것으로 생각된다.

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급성 폐동맥 색전증의 치험 1례 (Acute Massive Pulmonary Embolism - A Case Report -)

  • 전태국;안혁
    • Journal of Chest Surgery
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    • 제23권4호
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    • pp.811-815
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    • 1990
  • Successful emergency pulmonary embolectomy with the cardiopulmonary bypass was performed in a 41 \ulcorneryear old male who suffered massive pulmonary embolism after longterm bed rest due to the injury of left knee. Temporary cardiopulmonary bypass provided 120 minutes of circulatory support while complete removal of bilateral pulmonary emboli accomplished using Forgarty catheter and Gall stone forceps. Also, manual compression of the lungs was necessary to remove distal branching emboli. The patient had smooth and uneventful hospital course without complications and discharged from hospital taking coumadine on the 13th day after the operation.

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Dimethyl-esculetin이 Carbon-tetrachloride 부하가토혈청 Transaminase 활성도에 미치는 영향 (The Effect of Dimethyl-esculetin on the Serum Transaminase Activity of Rabbit Pretreated with Carbon-tetrachloride)

  • 이돈일
    • 생약학회지
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    • 제1권4호
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    • pp.115-118
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    • 1970
  • Antihepatotoxic effect of dimethyl-esculetin, the major constituent of herbal drug Artemisia capillaris $T_{HUNBERG}$ (Compositae) which has long been used as folk medicine for gall stone and hepatitis in Asian country (China and Japan, except Korea) was investigated on the rabbit intoxicated with carbon-tetrachloride. Ten rabbits were divided into two parts, group A and B in five each. The group A was injected with carbon-tetrachloride, 0.1ml per kg at begining of the experiments for control. The group B was injected with carbon-tetrachloride soon after 7 days treatment of dimethyl-esculetin, 30mg per day. The results obtained in this experiment were as follows.: 1) Antihepatotoxic activity of dimethyl esuletin on the rabbits intoxicated with carbon tetrachloride has shown the serum glutamic oxaloacetic transaminase activity and serum glutamic pyruvic transaminase activity decreased respectively. 2) The component of Artemisia capillaris, dimethyl-esculetin, has shown remarkable antihepatotoxic effect.

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담석을 동반한 담낭내 간질 감염 1례 (A Human Case of Ballbladder Fascioliasis in Korea)

  • 홍성태;이순형
    • Parasites, Hosts and Diseases
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    • 제24권1호
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    • pp.89-94
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    • 1986
  • 경북 문경군에 거주하는 48세의 남자가 반복되는 상복부의 선통을 주소로 점촌의 외과의원에서 진찰과 검사를 받은 결과 담낭내에 담석이 있음을 확인받고 수술을 위해 영남대학병원에 입원하였다. 1984년 11월 30일에 담낭절제술을 받아, 담석을 제거하였고, 수술 당시의 관찰에서 간과 담도에 별다른 소견이 없었다. 절제된 담낭의 병리 조직표본에서 담도에서 4cm되는 부위에 궤양, 출혈, 담낭벽이 국소적인 파괴 및 호산구를 위시한 염증세포의 전반적인 침윤등이 관찰되었고 괴사된 조직과 경계부에서 충란이 관찰되었다. 이 병변 부위를 긁어 모아 충란을 관찰한 결과 길이가 $143~155{\mutextrm{m}}$이고 난개가 있어, 간질(Fasciola sp.)의 충란으로 진단하였다. 이 증례를 문헌상 간질의 5번째 국내감염례로 보고한다.

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폐쇄성(閉鎖性) 황달의 진단에 관한 핵의학적(核醫學的) 고찰 (Scan Manifestation and Trace-Dose Radiogold Clearance Rates in Obstructive Jaundice)

  • 김동집;박용휘;신경섭
    • 대한핵의학회지
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    • 제3권2호
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    • pp.49-54
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    • 1969
  • The present study has been undertaken to analyze scan manifestations in obstructive jaundice. Scan changes were cprrelated with the duration of jaundice. In addition, clearance rates of trace dose of colloidal radiogold were assessed in each case. The materials were consisted of 19 cases with surgically and/or histopathlogically verified obstructive jaundice from various causes including common duct stone, empyema of the gall bladder and carcinoma of the pancreas head etc. Blood clearance rates of colloidal $^{198}Au$ were determined after the injection of 8 uCi by simple geometrical drawing of recorded strip charts. Scan was performed following additional injection of the same radiogold. In 16 out of 19 cases, the scan revealed rather typical "arborifrom" mottlings around the porta hepatis. The intensity and appearance of such mottlings on the scan was related with the duration of jaundice and level of serum bilirubin and alkaline phosphatase. The blood clearance rates remained to be within normal range in 74 percent of the patients. In the remaining 26 percent, clearance rates ranged between 4.1 and 6 minutes. It is concluded that the association of "arboriform" mottlings and normal or mildly delayed clearance rates in the patients with jaundice is characteristic of obstructive changes in the biliary system.

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ERCP 시술중 Balloon Cholangiography의 유용성에 관한 고찰 (A Study on Usefulness of Balloon Cholangiography in Operating ERCP)

  • 손순룡
    • 대한방사선기술학회지:방사선기술과학
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    • 제20권1호
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    • pp.43-49
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    • 1997
  • Purpose of this paper is to extend help for clinical application in balloon cholangiography on patients who have undergone endoscopic sphincterotomy, impacted stones of intrahepatic duct, and missed bile duct because of other diseases in operating endoscopic retrograde cholangiopancreatography. This study was done for the patients who had clinical signs of biliary diseases from January to December In 1996. We studied 45 patients who had endoscopic sphincterotomy, re-examination after interventional treatment of the endoscopic retrograde cholangiopancreatography, and uncertain diagnosis due to common bile duct and intrahepatic duct those are not filled with contrast media. Balloon cholangiography was performed in case of uncertain diagnosis while operating endoscopic retrograde cholangiopancreatography. First of all, we insert balloon catheter Into the working channel of treatment jejunofiberscope and remove treatment Jejunofiberscope after ballooning, and lastly take biliary tract X-ray after Injection and changing position of patient. The results of this study were as follows. (1) In classification of diseases, stones of gall bladder, those of common bile duct, and those of intrahepatic duct were 30 cases, fistula was 1 case. (2) In total cases of 45, only diagnosis were 25 cases, interventional treatment were 20 cases. (3) In case of interventional treatment, endoscopic sphincterotomy and endoscopic nasobiliary drainage, and stone removal were about the same, 7, 7, 6 respectively. Balloon cholangiography will be useful to prevent patients from having repeated and unnecessary studies for the cases above explained. It is considered that this study will be useful for clinical application in terms of reducing medical expenses, pain while examination, and consultation hours.

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담석증 환자의 식생활양식 및 영양 실태 조사 (A Descriptive Study of Gall Stone Patient's Dietary Habits and Nutritional Status)

  • 김은정;이영미
    • 대한지역사회영양학회지
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    • 제12권6호
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    • pp.826-837
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    • 2007
  • Gallstone composition has changed over the past decades in the Korean with a prominent increase in the prevalence of cholesterol gallstone. This trend is possibly due to the westernization of dietary habits. The purpose of this study was descriptive of GB patient's health related eating behaviors and nutrient consumption patterns. One hundred and six gallstone patients who have had cholecystitis surgery enrolled in this study. Anthropomertic indices, such as height, weight, waist circumference, and hip circumference were measured and calculated BMI and WHR. As the biomarker, TC, TG, LDL-C, HDL-C, FBG level and SBP/DBP were measured and analyzed the relationship with GB stone formation. The structured checklist of health related eating behavior and the semiquantitative food frequency questionnaire after pre-test was used in the face to face interview study. The mean age was $54.9{\pm}13.3$ and gallstone disease was more frequent in the fifties and sixties. Mean BMI was $24.3{\pm}2.8$ in males, and $23.4{\pm}3.9$ in females, the average of waist circumference was $91.1{\pm}7.0cm$ in males and females were $85.4{\pm}9.6cm$. The WHR of men and women was $0.93{\pm}0.0,\;0.90{\pm}0.1$, respectively. The obesity and overweight trend was observed in gallstone patients. The mean blood sugar was researched at $114.5{\pm}35.0mg/dL$. And the ratio of both symptoms DM and gallstone was 26.4%. The rate of dramatic eating repast was significantly higher in the females (p<0.01). Males tended to more frequently consume meat, of high fat content meats and greasy food consumption when eating out. The CPF ratio was 57:16.5:26.5. There was a significant positive correlation between WC and energy (r=0.252, p<0.05), carbohydrate (r=0.255, p<0.05) and niacin (r=0.227, p<0.05). In addition, carbohydrate were significantly correlatied with TC (r=0.230, p<0.05). BMI appeared positive in correlation of protein (r=0.201, p<0.05) and fat (r=0.205, p<0.05). These findings provide a little association that dietary habits are related with cholesterol gallstone formation.

심장이식후에 발생한 외과적 합병증 - 단일 센터 경험 - (Surgical Complications in Heart Transplant Recipients - A Single Center Experience -)

  • 박국양;박철현;전양빈;최창휴;이재익
    • Journal of Chest Surgery
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    • 제42권6호
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    • pp.719-724
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    • 2009
  • 배경: 심장이식이 최근 증가하면서 거부반응과 감염외의 외과적합병증도 증가하고 있다. 이 논문에서는 한 외과의에 실시된 심장이식후에 발생한 외과적합병증을 보고하고자 한다. 대상 및 방법: 1994년 4월부터 2003년 9월까지 실시된 37명의 심장이식환자를 대상으로 하였으며 심장이식의 적응은 확장성 심근증, 허혈성심근증, 판막심근증, 가족력심근증 등이었다. 결과: 총 15명의 이식환자에서 20예의 합병증이 발생하였으며 실시된 외과적 수술의 종류는 출혈로 인한 재개흉(5), 심낭액저류배액술(4), 인공박동기거치술(1), 아스페르질루스증에 의한 우하엽절제술(1), 요석제거술(1), 담낭제거술(1), 직장주위절개술(1), 부비동배액술(1), 고관절치환술(1), 치주비대에 의한 치주절개술(1), 뇨도절개술(1), 추간판 탈출증수술(1), 자궁근종으로 인한 자궁적출술(1)이 있었다. 합병증의 위치는 흉곽내가 10예, 흉곽외가 10예였다. 결론: 심장이식 수술후에는 흉곽 뿐만 아니라 다른 부위장기에 많은 합병증을 가져올 수 있기 때문에 장기생존율을 높이기 위해서는 다학제간의 적극적인 치료가 매우 중요하다.

Salmonella에 의한 농흉 1예 (A Case of Empyema by Salmonella)

  • 나득영;송일한;박명재;윤기헌;유지홍;강홍모
    • Tuberculosis and Respiratory Diseases
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    • 제42권1호
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    • pp.105-109
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    • 1995
  • 저자들은 53세 여자 환자에서 Salmonella Group B에 의한 농흉 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

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일개(一個) 종합병원(綜合病院) 건강검진자(健康檢診者)의 사상체질(四象體質)에 따른 만성병환(慢性病患)의 유병율(有病率)에 관(關)한 연구(硏究) (A Study on the Prevalences of Chronic Diseases according to Sasang Constitution at a Health Examination Center)

  • 이태규;이수경;최봉근;송일병
    • 사상체질의학회지
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    • 제17권2호
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    • pp.32-45
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    • 2005
  • 1. Objectives The purpose of this study was to find out prevalence of chronic diseases according to Sasang constitutional. 2. Methods The medical records of 1,453 subjects who have taken health examinations and diagnosis of Sasang constitution from January 2003 to June 2003 at a health examination center of a university hospital in Seoul were reviewed. Sociodemographic factors and the prevalences of chronic diseases according to Sasang Constitution are compared and analyzed. 3. Results (1) Among the 1,453 subjects, 683(47.0%) were Taeumin, 421(29.0%) were Soyangin, and 349(24.0%) were Soeumin. (2) The prevalences of gastric polyp, diabetes mellitus, obesity, hypertension, hyperlipidemia, dyslipoproteinemia, abnormal liver function and fatty liver of T aeurnin were significantly higher than those of the other constitutions (p-value<0.05). And the prevalences of hepatic cyst and gall stone disease of Taeumin were higher than those of the other constitutions(p-value<0.l). (3) The prevalences of liver cirrhosis of Soyangin was significantly higher than that of the other constirutions(p-value <0. 05). (4) The prevalences of pulmonary tuberculosis on X-ray and anemia of Soeurnin were significantly higher than those of the other constitutions (p-value<0.05). And the prevalences of gastric xanthelasma and hypothyroidism of Soeumin were higher than those of the other constitutions(p-value<0.1). 4. Conclusions There were significant differences on the prevalences of some chronic diseases according to Sasang wnstirution.

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