• Title/Summary/Keyword: GalN

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THAINE'S THEOREM IN FUNCTION FIELD

  • Jung, Hwanyup
    • Journal of the Chungcheong Mathematical Society
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    • v.22 no.1
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    • pp.17-23
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    • 2009
  • Let F be a finite real abelian extension of a global function field k with G = Gal(F/k). Assume that F is an extension field of the Hilbert class field $K_e$ of k and is contained in a cyclotomic function field $K_n$. Let $\ell$ be any prime number not dividing $ph_k{\mid}G{\mid}$. In this paper, we show that if $\theta{\in}\mathbb{Z}[G]$ annihilates the Sylow $\ell$-subgroup of ${\mathcal{O}}^{\times}_F/{\mathcal{C}}_F$, then (q-1)$\theta$ annihilates the Sylow $\ell$-subgroup of ${\mathcal{Cl}}_F$.

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Studies on the Antineoplastic Components of Korean Basidiomycetes (한국산(韓國産) 담자균류(擔子菌類) 항암(抗癌) 성분(成分)에 관한 연구(硏究))

  • Kim, Byong-Kak;Chung, Hee-Soo;Chung, Kyung-Soo;Yang, Moon-Sik
    • The Korean Journal of Mycology
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    • v.8 no.2
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    • pp.107-113
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    • 1980
  • To investigate antitumor components of Korean higher fungi, the carpophores of Ganoderma lucidum (Fr.)Karst. were collected at Gal-mae-ri in Gyeong-gi Province and extracted with 0.1N sodium hydroxide solution. The extract was purified by dialyzing through Visking tube and a dark brownish power was obtained. The antitumor activity of the fraction was tested against sarcoma 180 implanted in mice. The tumor inhibition ratio of the fraction against the tumor was 87.6% in doses of 50 mg/kg/day for the period of ten days. The tumor in five of 15 mice was completely regressed. The antitumor fraction was chemically analyzed and found to be a complex of polysaccharide and protein, from which four monosaccharides and eighteen amino acids were identified.

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A target-specific bioassay for screening of bioactive AHL-analogues from natural products

  • Kim, Young-Hee;Kim, Jung-Sun;Park, Sung-Hoon
    • 한국생물공학회:학술대회논문집
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    • 2002.04a
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    • pp.411-414
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    • 2002
  • Acylated homoserine lactones (AHLs) are membrane-permeant signal molecules responsible for biofilm formation of gram-negative bacteria via a unique mechanism known as quorum sensing. A target specific bioassay employing the AHL-responsive Agrobacterium tumefaciens reporter strain has been developed to identify new AHL-like compounds from natural products, which could be developed into antifouling compounds. By varying the X-gal concentration, incubation time, solvent for sample preparation and the sample loading procedure, it was possible to detect low level AHLs up to $10^1nM$. The length of the acyl chain of the AHLs was found to affect the sensitivity of this bioassay.

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Investigation of pollutant in Shin-gal reservoir and inflow streams (신갈호 및 유입하천의 오염도 조사)

  • Jung, Hee-Jin;Choi, I-Song;Oh, Jong-Min
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.1028-1032
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    • 2007
  • 현재 용인시에서는 기흥 호수공원을 2010년까지 신갈저수지 일대 118만평에 여가와 문화, 휴양시설이 연계된 대규모 유원지로 조성한다는 계획을 가지고 있다. 이에 본 연구에서는 신갈호소 및 유입하천의 오염실태를 조사하여 호수공원 조성 시 기초 데이터의 확충 및 현황파악을 위하여 신갈호 및 유입하천의 모니터링을 실시 하였다. 조사결과 신갈호 및 유입하천의 지점별 수질 현황은 SS, COD, T-N, T-P 등 대부분의 항목에서 호소 수질 관리기준 $IV{\sim}V$등급의 수질현황을 나타내고 있었다. 본 조사연구 결과는 앞으로 호수공원이 조성되는 신갈호를 효율적으로 관리함에 있어 중요한 근거자료가 될 수 있을 것으로 판단되며, 수질개선사업의 수행 시 설계 인자로 반영 하고자 한다.

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Polymerization of p-Chlorophenyl Propargyl Ether by Molybdenum- and Tungsten- Based Catalysts

  • Lee, Won-Chul;Seo, Jang-Hyuk;Gal, Yeong-Soon;Jin, Sung-Ho;Choi, Sam-Kwon
    • Bulletin of the Korean Chemical Society
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    • v.14 no.6
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    • pp.708-712
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    • 1993
  • The Polymerization of p-chlorophenyl propargyl ether (CPE) was carried out using various transition metal catalysts. The catalytic activity of $MoCl_{5}$-based catalysts was greater than that of $WCl_6$-based catalysts. $MoCl_5$ alone and $MoCl_{5}$-cocatalyst systems polymerized CPE very effectively to give a high yield of poly(CPE). In most cases, the polymer yield was quantitative and the average molecular weight $({\bar{M}}n)$ was in the range of 9,000 and 17,000. The NMR, IR, UV-visible spectra indicated that the present poly(CPE) has a linear conjugated polyene structure having p-chlorophenyl oxymethylene substituent. The poly(CPE) was mostly dark-brown colored powder and was completely soluble in various organic solvents such as chloroform, methylene chloride, THF, chlorobenzene, etc. The X-ray diffraction analysis indicated that the present poly(CPE) is amorphous.

Protective agents against sepsis from the root bark of Paeonia suffruticosa

  • Li-Gao;Xu , Ming-Lu;Seo, Chang-Seob;Kim, Hyo-Jin;Lee, You-Jeong;Lee, Yeun-Koung;Son, Jong-Keun;Song, Dong-Keun
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.199.2-199.2
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    • 2003
  • The bioassay-guided fractionation of protective agents against sepsis-induced lethality from the root bark of Paeonia suffruticosa led to the isolation of ten known compounds: paeonol (1), 2,5-dihydroxy-4-methoxyacetophenone (2) methyl 3-hydroxy-4- methoxybenzoate (3), acetovanillone (4), benzoic acid (5), benzoylpaeoniflorin (6), paeonoside (7), paeoniflorin (8), oxypaeoniflorin (9) and apiopaeonoside (10). Among them, 4 exhibited the highest survival rate in a dose-dependent manner (100% with a dose of 30 mg/kg versus 16.7% for the control experiment) and showed reduction of plasma alanine aminotransferase (ALT) value on the in vivo assay model of sepsis induced by LPS/GalN.

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Ligand and Dimerization Dependent Transactivation Capability of Aromatic Hydrocarbon Receptor

  • Park, Hyun-Sung
    • BMB Reports
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    • v.32 no.3
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    • pp.279-287
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    • 1999
  • The aromatic hydrocarbon receptor (AhR) is a cytosolic protein that binds the environmental pollutant, dioxin. The liganded AhR translocates into the nucleus where it heterimerizes with a constitutive nuclear protein, AhR nuclear translocator (Arnt). The N-terminal regions of both AhR and Arnt contain basic helix-loop-helix (bHLH) and Per-AhR-Arnt-Sim (PAS) motifs that are required for DNA binding, dimerization, and ligand binding whereas the C-terminal regions of both AhR and Arnt contain transactivation domains. Here, results from the mammalian two-hybrid system indicate that Arnt can make a homodimer but AhR cannot. In the presence of dioxin, the interaction between AhR and Arnt is stronger than that of the Arnt homodimer, suggesting that Arnt prefers to make a heterodimer with the liganded AhR rather than a homodimer. Transfection analyses using the GAL4-driven reporter system suggest that AhR's N-terminal region represses its own transactivation domain, as well as exogenous transactivation domains such as Sp 1 and VP16. Interestingly, the repressed transactivation domains of AhR are activated by ligand-dependent heterodimerization with Arnt. These observations suggest that heterodimerzation with Arnt is necessary not only for DNA binding but also for activation of the repressed transactivation capability of AhR.

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Neutral and Amino Sugars Composition of a Lectin from Maackia fauriei (Maackia fauriei 유래 렉틴의 중성당 및 아미노당 조성)

  • Na, Kwang-Heum;Park, Byung-Tae;Park, Jae-Wan;Han, Kyong-Jin;Park, Hyun-Joo;Kim, Ha-Hyung
    • YAKHAK HOEJI
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    • v.53 no.1
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    • pp.34-40
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    • 2009
  • The glycosylation of therapeutic glycoproteins can affect their efficacy, stability, solubility, and half-life. Analyzing the composition of monosaccharides, such as that of neutral and amino sugars, is the first step for elucidating the structure of glycan attached to glycoproteins. In the present study, neutral and amino sugars of lectin obtained from Maackia fauriei were analyzed using an enzyme-linked lectinsorbent assay (ELLA) and high-performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD). Peroxidase-labeled lectins such as concanavalin A, Ricinus communis agglutinin, and soybean agglutinin were used for ELLA, since they specifically bind to the monosaccharide residue most frequently encountered in a glycan. The hydrosylate of lectin was prepared by treatment with trifluoroacetic acid, which resulted in the lectin mainly possessing the N-glycan consisting of 98.1 pmol Fuc, 342.1 pmol GlcN, 51.9 pmol Gal, 678.9 pmol Man, and 330.7 pmol Xyl. The present results demonstrate that ELLA and HPAEC-PAD are very effective methods for rapidly estimating the types and relative amounts of monosaccharides in intact glycoproteins.

Expression of Heterotic Genetic Interaction among Multivoltine Recurrent Backcross/Congenic Lines for Higher Shell Weight of Silkworm, Bombyx mori L.

  • Verma, A.K.;Chattopadhyay, G.K.;Sengupta, M.;Sengupta, A.K.;Das, S.K.;Urs, S.Raje
    • International Journal of Industrial Entomology and Biomaterials
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    • v.7 no.1
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    • pp.21-27
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    • 2003
  • Manifestation of heterotic genetic interaction was studied in different hybrids made between multivoltine recurrent backcross (RBL)/congenic lines (Con. L) during unfavourable season when temperature and relative humidity are > $30^{\circ}C$ and 86%, respectively. A few number of silkworm race or strain or breed like Nistari (N + p or Np) can sustain the temperature above 3$0^{\circ}C$ and RH above 86%. The present heterosis study screened a hybrid i.e., CB$_{5}$Lm5RBL1M$_{6}$DPC-LmE$^1$RBL and its reciprocal provided heterobeltiotic effect on survival by number and pupation rate at a magnitude of 20% (p < 0.01) and yield by weight of 10% (p < 0.01). Beside all the hybrids expressed heterosis over check - Nistari (N + p) with better quality silk. Therefore, aforesaid hybrid may be useful for utilization at commercial level during adverse seasons of West Bengal.gal.

Effects of antimony addition on growth of InGaN nano-structures by mixed-source HVPE (혼합소스 HVPE 방법에 의한 InGaN 나노구조의 성장에 있어서 Sb 첨가의 영향)

  • Ok, Jin-Eun;Jo, Dong-Wan;Jeon, Hun-Soo;Lee, Ah-Reum;Lee, Gang-Suok;Cho, Young-Ji;Kim, Kyung-Hwa;Chang, Ji-Ho;Ahn, Hyung-Soo;Yang, Min
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.20 no.3
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    • pp.113-116
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    • 2010
  • We report on the growth and characteristics of the structural and optical properties of InGaN nano-structures doped with antimony (Sb) as a catalyst. The use of catalyst has been explored to modify the growth and defect generation during strained layer heteroepitaxial growth. We performed the growth of the InGaN nano-structures on c-sapphire substrates using mixed-source hydride vapor phase epitaxy (HVPE). The characteristic of samples was measured by scanning electron microscope (SEM) and photoluminescence (PL). The aligning direction of c-axis of the InGaN nano-structures was changed from vertical to parallel or inclined to the surface of substrates when the Sb was added as a catalyst. The indium composition was estimated about 3.2% in both cases of with or without the addition of Sb in the InxGal-xN structures. From the results of InGaN nano-structures formed with the addition of Sb, we can expect the performance of optical devices would be more improved by reduced piezo-electric field if we use the InGaN nano-structures of which c-axes are aligned parallel to the substrates as an active layer.