• KSBB Journal
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• 제27권2호
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• pp.97-102
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• 2012

In the present study, the biomass productivity of two green microalgae (Chlorella sp. and Dunaliella salina DCCBC2) were assessed in a 12 L tubular photobioreactor under optimum culture conditions. In the batch culture optimization process, the Chlorella sp. biomass was obtained as 1.2 g/L under atmospheric air as a sole $CO_2$ source and other culture conditions as follows: light intensity, temperature, pH, $NH_4Cl$ and $K_2HPO_4$ were 100 ${\mu}E/m^2/s$, $27^{\circ}C$, 7.0, 20.0 mM and 2.0 mM, respectively. On the other hand, 2.9 g/L of D. salina DCCBC2 biomass production was observed under the following conditions: light intensity, temperature, pH, $KNO_3$ and $K_2HPO_4$were 80 ${\mu}E/m^2/s$, $27^{\circ}C$, 8.0, 3.0 mM and 0.025 mM, respectively. At 1% $CO_2$ supply to the reactor, the Chlorella sp. production was reached 1.53 g/L with 25% increment under the same operating conditions. In addition, the maximum D. salina DCCBC2 biomass was observed as 3.40 g/L at 3% $CO_2$ concentration. Based on the aforementioned optimized conditions, the dilution rate and maximal biomass productivity of Chlorella sp. and D. salina DCCBC2 in the continuous cultivation were 0.4/d and 0.6 g/L/d and 0.6/d and 1.5 g/L/d, respectively.

• 한국항공우주학회지
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• 제45권3호
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• pp.173-179
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• 2017

본 논문에서는 모션캡쳐 카메라를 사용한 실험을 통해 날갯짓 비행체의 주 날개, 꼬리날개 구동기 특성 분석에 대하여 기술하였다. 실험은 빛이 차단된 실내에서 진행되었고 지그에 기체를 고정하여 날갯짓으로 인한 영향을 줄였다. 주 날개와 꼬리날개 끝단에 마커를 부착하였고 모션캡쳐 카메라는 입력 신호에 대한 각각의 반응을 측정한다. 실험 결과 주 날개는 날갯짓의 주파수에 따라 진폭이 변하는 경향을 보였고, Modified Strip Theory에 실험 결과와 비행체 제원을 적용하여 양력 및 추력 발생 시뮬레이션을 구현 하였다. 꼬리날개는 종 횡축별로 스텝 신호를 인가하여 이에 따른 결과를 2차 전달함수 형태로 정의하였고, 각 축별로 구동기의 구조 차이로 인하여 최종 응답시간, 오버슈트, 최대값 등에서 차이를 나타내는 것을 확인하였다.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2007년도 추계학술발표회
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• pp.177-183
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• 2007

제어봉이 부착된 원관 후류의 유동특성을 관찰하기 위해 입자영상유속계(PIV)를 사용한 계측을 수행하였다. 실험은 소형회류수조에서 유업 유속을 0.lm/s, 0.2m/s, 0.4 m/s 로 하고, 원관(D=50mm) 에 제어봉이 없는 경우와 제어봉이 5mm, 10mm, 20mm 가 부착된 총 l27가지로 정하였고, 속도신호에 따른 주파수특성을 고찰하였다. 실험에서 제어봉의 영향으로 인하여 와류흘림 주파수가 작게 나타났으며, 유동제어의 지배변수로는 d/D와 레이놀즈수이며, 원관 후류의 주파수특성에 큰 영향을 미쳤다. 와류흘림 주파수는 제어봉이 0.20인 경우 가장 작게 나타났다.

• 한국인터넷방송통신학회논문지
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• 제15권2호
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• pp.239-244
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• 2015

SNS(Social Networking Service)와 쇼핑몰을 결합하면 오프라인 거래에서처럼 단골 관계를 형성할 수 있다. 농산물 직거래의 예를 들면, 소비자는 자신의 SNS 홈에서 기존의 단골 관계인 생산자의 소식(파종, 농사, 수확, 신상품 등)을 타임라인에서 확인하여 필요한 상품을 원클릭(one click)으로 구매할 수 있고 생산자는 소비자에게 뉴스 및 할인 등의 정보를 제공하여 단골로 만드는 고객 관리가 가능하다. 이처럼 SNS의 인맥 마케팅 기능에 더하여 시스템은 생산자의 판매 물품을 자동 분류한 카테고리로 소비자의 SNS 홈 페이지에 쇼핑물의 기능을 제공하여 소비자가 원하는 상품을 검색하고 구매할 수 있으며 구매는 자동으로 소비자와 생산자를 단골관계로 이어준다. 구매자는 구매한 상품에 대한 추천 및 리뷰 작성을 통해 기존의 리뷰 재배포도 가능하며 서로 알지 못하는 구매자 간의 소통을 가능하게 한다는 것이 이 시스템의 가장 큰 특징이다.

• 혜화의학회지
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• 제19권2호
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• pp.101-118
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• 2011

Herbal medicine has a high body absorption rate when it ferments. Biological and clinical research on the fermented herb gradually increases because it has effective materials for the treatment of a disease and it is a little bitter. In this study, we investigated the effect of fermented Baedokhwanbalhyobang (BDHBH) on attenuation of the development of atopic dermatitis in NC/Nga mice by evaluating the cytokine level in serum, the mRNA expression of cytokine and histological alteration of the skin, and the skin severity. We have come to the following conclusion. BDHBH led to a significant decrease in the skin severity score (63.1%) as compared to the control group. CD4+/CD45+, CD4+, B220+/CD23+, and CD11b+/Gr-1+cells of peripheral mononuclear cells (PBMCs) in the BDHBH-treated group were decreased to 6.7%, 31.1%, 22.4%, 36.6%, respectively. CD3+and CD11b+/Gr-1+immune cells in dorsal skin of the BDHBH-treated group were decreased to 52.9% and 28.0%. The levels of IL-5 and IL-13 in serum of the BDHBH-treated group were inhibited to 18.8% and 5.1%. The mRNA expressions of IL-5 and IL-13 in dorsal skin were also decreased to 30.6% and 27.8% after the treatment of BDHBH. BDHBH inhibited the proliferation and differentiation of eosinophils. In histological examination, BDHBH decreased the thickness of epidermis and dermis, and infilatration of mast cells as compared to the control group. These results indicate that BDHBH inhibits the pathogenic development of atopic dermatitis in NC/Nga mice. These results may indicate that BDHBH attenuates the development of atopic dermatitis-like lesions by lowering immune cells and inflammatory cytokine levels, and that it is valuable in drug development for the treatment of atopic dermatitis. Further experiments on the components of BDHBH will be needed to better understand the effect of a fermented herb as compared to a herb.

• 혜화의학회지
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• 제19권2호
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• pp.85-100
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• 2011

In order to investigate the efficacy of HYGBH on atopic dermatitis, various immune related factors were studied. The results and conclusions are as follows. Atopic dermatitis symptoms were improved in HYGBH treated group and significant decrease in dermatitis index were observed in 12 and 14 weeks. HYGBH treated group showed significant decrease in CD4+, CD3+/CD69+ immune cell ratio in PBMC by 18% and 40.6% respectively. HYGBH treated group showed significant decrease in CD3+, CD11b+/Gr-1+ immune cell ratio in dorsal skin by 44.6% and 53.1% respectively. HYGBH treated group showed significant decrease in IL-4, IFN-${\gamma}$ in spleen by 29.5%, 7.7% respectively. HYGBH treated group showed decrease in the expression of IL-5, IL-13, IL-17 and histamine by 21%, 9.6%, 14%, and 32.2% respectively. Also the group showed decrease in the expression of IgE by 6.8% respectively. HYGBH treated group showed significant decrease in the transcription of IL-5 and IL-3 mRNA in skin by 35.5% and 23.2% respectively. The results above indicated that treatment of HYGBH improved atopic dermatitis symptoms by anti-oxidant activity as well as immune modulation activity as a clinical evidence. Also, to increase the application of fermented oriental medicine, different fermentation conditions using various microbial strains should be accumulated as the clinical evidence in the future.

• 혜화의학회지
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• 제19권2호
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• pp.65-83
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• 2011

Various related factors and tissue changes in vitro and in vivo were observed to investigate the efficacy of HYBH on atopic dermatitis. The results are described below. HYBH improved the atopic dermatitis symptoms by naked eye examination, and significantly decreased dermatitis clinical index at 14 weeks. HYBH significantly decreased CD4+/CD45+, CD4+, CD8+, CD3+/CD69+ immune cell ratios in PBMC by 28%, 16%, 30%, 26% and 22% respectively. HYBH significantly decreased CD11b+/Gr-1+, CD3 immune cell ratios in dorsal skin by 35.3% and 67.5% respectively. HYBH significantly decreased the expression of IL-4 and IFN-${\gamma}$ in spleen by 23% and 15% respectively. HYBH significantly decreased the production rate of IL-5, IL-13 and histamine in serum by 17%, 23%, and 8.8% respectively and increased IL-17 production by 17%. HYBH significantly decreased immunoglubulins IgG1 and IgE production in serum. The results above indicated that treatment of HYBH improved atopic dermatitis symptoms by anti-oxidant activity and immune modulation activity as a clinical evidence. Also, different fermentation conditions using various microbial strains should be accumulated as the clinical evidence for broad application in the future.

• 한국응용곤충학회지
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• 제19권4호
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• pp.221-227
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• 1980

1979년 7월 경남 김해에서 딸기 성강 16호의 잎에 흑갈색 내지 암갈색 병반을 형성하는 병해를 발견, 그 병원균을 분리 검토한 결과 우리나라에서는 미기록병해인 Alternaria alternate (Fr.) Keissler로 동정되었으며 본병을 검은무늬병이라 명명하였다. 본균의 분생포자의 형태는 배지간에 차가 심하였으며 C.M.A.에서 평균 $20.1\times9.3{\mu}$, beak의 길이는 $4.0{\mu}$으로서 자연감염된 딸기잎상에서 형성된 것 보다 짧았다. 딸기 49품종에 접종한 결과 성강 16호와 Robinson이 고도감수성이였으며 Catskill, Cyclone, Northwest, Merton princes, Juspa, 및 대학 1호 등의 품종에도 발병을 볼 수 있었으나 31 품종은 전연 발병되지 않았다. 10종(14품종)에 접종한 결과 해바라기, 겹해바라기, 및 멕시코 해바라기에만 심하게 발병되었다.

• The Journal of Korean Physical Therapy
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• 제15권4호
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• pp.208-234
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• 2003

This study aims to investigate the effect of Neuromuscular Re-education Program and Traditional Intervention Program and is focusing on the difference between changes of experimental before and after on 30 stroke patient's body composition, blood lipid levels, physical motor function. The obtained results are as follows; 1. Change in body composition 1) The change due to the Neuromuscular Re-education Program and Traditional Intervention Program before and after, the Fat Mass and Soft Lean Mass were changed but not significantly. 2) In the comparison of change according to duration, Significant differences were not shown in Fat Mass and Soft Lean Masss between The experimental group and control group. 2. Change in blood lipid levels 1) The change due to the Neuromuscular Re-education Program and Traditional intervention Program before and after, the Cholesterol, Glucose and TG were changed but not significantly. 2) In the comparison of change according to duration, Significant differences were not shown in the Cholesterol, Glucose and TG between the Experimental group and Control group. 3. Change in physical motor function 1) The change due to Neuromuscular Reeducation Program before and after. The physical motor function was significantly changed(p<0.01; p<0.05). but Traditional Intervention Program was changed but not significantly. 2) In the comparison of change according to duration, Signicant differences between the Experimental group and Control group was significantly changed in only the Neuromuscular Reeducation Program(p<0.05). In conclusion, The Neuromuscular Reeducation Program were not changed significantly but it can be said that the Neuromuscular Reeducation Program was more suitable for intervention to improve physical motor function of stroke patients than Traditional Intervention Program. Therefore if further studies increase the experimental duration of Reeducation Program and make the patient's reeducation continuously for improvement of physical motor function in stroke patient are needed.

• 동의생리병리학회지
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• 제26권4호
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• pp.446-454
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• 2012

In order to evaluate the efficacy of SHT against atopic dermatitis (AD), various immune related cytokines as well as histological comparison were performed in animal models, and the results are described. Clinical skin index of the SHT treated group decreased significantly in weeks 11 and 13, compared to the control group. Also, CD4+ immune cell ratio in the dorsal skin was significantly decreased to 69%, and both epidermal and dermal skin thickness was decreased. Serum IL-4, IL-5, IL-6, IL-13, and TNF-${\alpha}$, which are all important markers of inflammation, were decreased to 64%, 44%, 87%, 48%, and 45%, respectively. The expression of histamine, a chemical transmitter increasingly released during the progression of inflammation, was significantly decreased to 47%. The production of IgE immunoglobulin was significantly decreased to 16% compared to the control group. In conclusion, SHT pacifies the activation of T cells, leading to suppression of both Th2 cytokine overexpression and infiltration of immune cells into skin. As a result, relative thinning of both epidermis and dermis were observed. With the results obtained from in vitro studies, the immune modulatory effect of SHT in AD animal models was experimentally demonstrated. This study should provide solid information to construct EBM and for clinical practice.