• Steel and Composite Structures
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• 제43권2호
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• pp.139-152
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• 2022

Steel-reinforced concrete (SRC) L-shaped column is the vertical load-bearing member with high spatial adaptability. The seismic behavior of SRC L-shaped column is complex because of their irregular cross sections. In this study, the hysteretic performance of six steel truss reinforced concrete L-shaped columns specimens under the combined loading of compression, bending, shear, and torsion was tested. There were two parameters, i.e., the moment ratio of torsion to bending (γ) and the aspect ratio (column length-to-depth ratio (φ)). The failure process, torsion-displacement hysteresis curves, and bending-displacement hysteresis curves of specimens were obtained, and the failure patterns, hysteresis curves, rigidity degradation, ductility, and energy dissipation were analyzed. The experimental research indicates that the failure mode of the specimen changes from bending failure to bending-shear failure and finally bending-torsion failure with the increase of γ. The torsion-displacement hysteresis curves were pinched in the middle, formed a slip platform, and the phenomenon of "load drop" occurred after the peak load. The bending-displacement hysteresis curves were plump, which shows that the bending capacity of the specimen is better than torsion capacity. The results show that the steel truss reinforced concrete L-shaped columns have good collapse resistance, and the ultimate interstory drift ratio more than that of the Chinese Code of Seismic Design of Building (GB50011-2014), which is sufficient. The average value of displacement ductility coefficient is larger than rotation angle ductility coefficient, indicating that the specimen has a better bending deformation resistance. The specimen that has a more regular section with a small φ has better potential to bear bending moment and torsion evenly and consume more energy under a combined action.

• Radiation Oncology Journal
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• 제16권1호
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• pp.43-49
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• 1998

배경 : 담낭 및 간외 담도계 악성종양의 5년 생존율은 $10\%$ 이하로 비교적 예후가 불량한 것으로 알려져 있다. 이러한 질환에서 방사선치료가 증상 완화 및 전체 생존율을 향상시키는 것으로 알려져 있어, 본원의 환자를 대상으로 후향적 분석을 시행하여, 방사선치료의 역할을 알아보고자 하였다. 방법 : 1984년 2월부터 1995년 11월까지 인제대학교 부속 백병원 방사선종양학과에서 담낭 및 간외 담도계 악성종양으로 완치 목적의 방사선 치료를 받은 43명의 환자중 3000cGy 이하의 방사선량 을 조사받은 10명을 제외한 총 33명의 환자(담낭 악성 종양은 21명, 간외 담도계 악성종양 12명)를 대상으로 하였다. 남녀 비는 전체 11명대 22명(담낭 악성종양 4:17, 간외 담도계 악성종양 7:5)이었고, 연령분포는 35-77세(중앙값 61세)이었다. 병기별로는 IV기가 19명으로 가장 많았으며, 재발후 방사선치료를 받은 경우가 3명 포함되었다. 방사선치료는 4MV 선형가속기를 사용하여 총 31.44-54.87Gy(중앙값 44.25Gy)가 조사되었고, 3명의 환자에서는 체외조사 전후로 근접치료가 추가되었다. 방사선조사 단독치료는 6명, 수술 후 방사선 치료는 27명에서 시행되었고, 이 중 16명만이 근치적절제술을 시행받았다. 항암화학요법은 17명에서 병행되었으며 이중 11명이 Mitomycin+5-FU+Leucovorin을 사용하였다. 결과 : 총 추적관찰 기간은 2-97개월(중앙값 8.5개월)이었다. 전체 환자의 2년 생존율은 $29.9\%$, 5년 생존율은 $13.3\%$로 나타났다. 질환별로는 담낭의 경우 2년 생존율이 $34.5\%$, 간외담도계 악성종양은 $27.8\%$이었다. 수술 후 방사선치료를 시행받은 환자들의 2년 생존율은 $30.1\%$이며, 이 중 근치적 절제술을 시행받은 16명의 2년 생존율은 $43.8\%$로, 부분절제 및 우회수술후 방사선치료를 시행받은 17명의 $20.7\%$보다 높게 나타났으나 통계적 유의성은 없었다(p>0.05). 병기별로는 1, II기의 2년 생존율이 $66.6\%$, III, IV기는 $23.6\%$로 통계학적으로 유의한 차이를 나타내었다(p<0.05). ECOG에 의한 임상수행능력정도에 따른 2년 생존율은 2급과 3급이 각각 $41.9\%$, $16.7\%$로 통계학적으로 유의한 차이를 나타내었다(p<0.05). 항암화학요법을 병행한 군의 2년 생존율은 $40.5\%$로 항암화학요법을 병행하지 않은 군의 $22.6\%$ 보다 비교적 높게 나타났으나 통계적 유의성은 없었다(p>0.05). 결론 : 본 연구결과 전체 환자의 2년 생존을과 5년 생존율은 $29.9\%$와 $13.3\%$로 나타났으며, 병기가 낮고, 임상수행능력이 높을수록 생존율이 향상됨을 알 수 있었다. 또한 근치적 절제술후 방사선 치료를 받은 환자와 항암화학요법을 병행한 군의 치료성적이 비교적 높은 것으로 볼 때, 담낭 및 간외담도계 악성종양환자중 일부에서 적극적인 병합치료요법이 생존율의 향상에 도움을 줄 것으로 기대된다.

• Journal of Acupuncture Research
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• 제24권4호
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• pp.43-54
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• 2007

Objectives : This study was designed to evaluate the effect of acupuncture with various scales on symptoms of Idiopathic Parkinson's disease. Methods: Subjects were voluntarily recruited through newspapers and internet advertisement. All the subjects were confirmed as idiopathic parkinson's disease by a neurologist. The acupuncture therapy was performed twice a week for 4 weeks by oriental medical doctor at Kyung-hee University hospital. Patients were randomly assigned to three groups : sham acupuncture group, acupuncture treatment group and Sasang-Constitution acupuncture treatment group. Acupun cture points used in acupuncture treatment group were $GB_{34}$, $LR_3$, and $ST_{36}$, which were proven to be effective in rat Parkinson's disease study. Acupuncture points used in sham treatment were non-acupoints near $GB_{34}$, $LR_3$, and $ST_{36}$. In Sasang-Constitution acupuncture treatment, we classfied Sasang constitution of patients by QSCCII. Acupuncture was applied based on theory of Korean medicine. The patient's symptoms were assessed at baseline and after 4 weeks of treatment by one evaluator with Unified Kingdom Parkinson's Disease Rating Scale (UPDRS), modified Hoehn-Yahr(H-Y) stage, and Schwab & England activ ity of daily living and freezing of gait questionnaire (FOGQ). Results : The results were as follows ; 1. UPDRS IV score differences between sham group and Sasang-Constitution acupuncture treatment were statistically significant(p=0.001). 2. UPDRS total score differences between Sasang-Constitution acupuncture treatment and acupuncture treatment group, Sasang-Constitution acupuncture treatment and sham group were statistically significant(p=0.041, p=0.014). 5. FOGQ score differences between Sasang-Constitution acupuncture treatment and acupuncture treatment group, Sasang-Constitution acupuncture treatment and sham group were statistically significant(p=0.001, p=0.001). Conclusion : The results suggest Sasang-Constitution acupuncture treatment can be applicable to improve symptoms in patients with idiopathic Parkinson's disease.

• 대한약침학회지
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• 제17권4호
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• pp.66-69
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• 2014

Objectives: Treating complex regional pain syndrome (CRPS) is difficult because it still does not have a recommended therapy. A 29-year-old man was diagnosed with CRPS after surgery on his $4^{th}$ and $5^{th}$ left toes 7 years ago. Though he had undergone diverse pain treatment, the symptoms persisted, so he visited Dunsan Korean Medicine Hospital of Daejeon University. This case report presents results on the effect of bee venom pharmacopuncture in treating patient with CRPS. Methods: Bee venom pharmacopuncture (BVP), 0.15 to 0.4 mL dosage, was administered at GB43. The treatment was applied each week for a total 14 times. The symptoms were evaluated using a numeric rating scale (NRS) and the dosage of pain medicine. Results: On the first visit, he was taking an anticonvulsant, a trycyclic antidepressant, and an analgesic. On the NRS the worst pain in the toes received a score of 8. He also complained of severe pain and hypersensitivity when the $4^{th}$ and the $5^{th}$ toes were touched just slightly. Other complaint included dyspepsia, rash, and depression. After treatment, on the NRS, the score for toe pain was 0, and he no longer needed to take pain medication. During the 4-months follow-up period, he has remained without pain; neither have additional symptoms appeared nor adverse events occurred. Conclusion: BVP may have potential benefits for treating patients with CRPS.

• Journal of Acupuncture Research
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• 제18권3호
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• pp.227-238
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• 2001

Objective : There was no report on the treatment of Fascioscapulohumeral (FSH) Muscular Dystrophy by Oriental medicine. But the treatment conducted on the patient admitted to the Sangji Oriental Medicine Hospital from January 9, 2001 to February 23, 2001, a significant treatment result was yielded and would like to suggest treatment plan for the future treatments. Methods : Under the assumption that Korean Bee-Venom Therapy may be affective for treating FSH Muscular Dystrophy, the following points were administered : SI10(노유), SI11(天宗), BL23(腎兪), BL26(關元兪), ST36(足三里), LI4(合谷), Liv3(太衝), SI9(肩貞). CFC(Carthami Flos;紅花 and Cervi Pantotrichum Cornu;鹿茸) herbal extract was treated on the other acupuncture points. Sa-Am(Four needle technique) Acupuncture (tonifying SI5 and ST42, sedating GB41 and ST43) was done every day. For herbal medicine, TaeEumIn ChoWiSeungChung-Tang was given based on the constitutional diagnosis. Results : After 7 weeks of treatment, a remarkable improvement was made for facial muscular movement and muscular strength of the scapular and another regions. Conclusions : 1. Significant improvement in the muscular strength for the case of FSH Muscular Dystrophy was obtained with through Korean Bee-Venom Therapy, Four needle technique, and herbal medication. 2. For progressive muscular dystrophy, it is necessary to practice muscular strength recovery exercise in conjunction with Korean Bee-Venom Therapy. 3. Although this case yielded favorable result, further observation and study must be made to concretely prove the effectiveness of Korean Bee-Venom Therapy for treating muscular dystrophies.

• 보험의학회지
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• 제4권1호
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• pp.77-85
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• 1987

We'd performed the upper gastrointestinal study for a total of 1,033 insureds-male 630, female 403 persons-who were examined at medical dept. of Dae Han Kyoyuk Insurance Co., Ltd., from August, 1986 to January, 1987. The results on diverticulum were as follows; 1. The incidence rate of duodenal diverticulum is exceptionally higher than esophageal diverticulum. 2. In all of 53 insured who have duodenal diverticulum and esophageal diverticulum, there was little difference between male and female in the incidence rate of diverticulum; 5.08% in male, 5.21% in female. 3. The possessing rate of both diverticulums increased by age regardless of sex. ; 0.71% in 20yrs, 2.12% in 30yrs, 11.11% in 40yrs, 12.75% in 50yrs, 30.43% in 60yrs more. 4. The possessing rate of both diverticulums in male is 0% in 20yrs, 1.97% in 30yrs, 7.21% in 40yrs, 15.09% in 50yrs, 27.27% in 60yrs more and in female, 1.16% in 20yrs, 2.40% in 30yrs, 7.87% in 40yrs, 10.20% in 50yrs, 33.33% in 60yrs more. 5. Those who have duodenal diverticulum 47 insureds felt the following subjective symptoms; uncomfortable 8.51%, heartburn and tingling each 4.26%, sore throat 2.13%and esophageal diverticulum's heartburn 16.67%. 6. There occurred the following complications in 47 insureds with duodenal diverticulum-gastric polyp, erosive gastritis, antral gastritis, cascade stomach, fatty liver, polyp in GB and choledocholithiasis; each 2.13% and cholelithiasis 6.38% and cascade stomach. 7. All duodenal diverticulum occurred in duodenal inlet. 8. The number of lesion was single in all esophageal diverticulum, but there was each one case with 2 lesions and 3 lesions in duodenal diverticulum.

• 한국치위생학회지
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• 제14권6호
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• pp.921-926
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• 2014

Objectives: The purpose of the study is to investigate the factors associated with gingival bleeding(GB) by tooth brushing in college students. Methods: A self-reported questionnaire was filled out by 232 college students in Daegu Health College from March to June, 2014. Data were analyzed for frequency, chi square test, and logistic regression analysis using SPSS 12.0 program. The study was a cross sectional study. The questionnaire consisted of general characteristics of the subjects(gender, age, marital status, and smoking), frequency and duration of tooth brushing, scaling experience, and physical health status. Self-reporting hemorrhage was reported by yes or no. Frequency of tooth brushing was documented as the number of behavior. Above 4 times of tooth brushing was defined as 4. Duration of tooth brushing was documented as minute. Above 4 minutes, it was recorded as 4. In physical health status, 1 is feeling weak and 4 is feeling very healthy. Cronbach alpha was 0.82 in the study. Results: There were significant relationships between gingival bleeding and age(p<0.05), subjective health(p<0.01), tooth brushing frequency(p<0.05) and duration(p<0.05) by chi square test. Logistic regression analysis showed that the age(p<0.05), subjective health(p<0.01), tooth brushing frequency(p<0.05) and duration(p<0.05) were associated with gingival bleeding. Prevalence of gingival bleeding in 20 years was 0.62(odds ratio 1.85, 95% CI 1.00~3.43) and it was higher than that in 10 years. Prevalence of gingival bleeding in good health group was -1.38 and it was lower than that in poor health group. Conclusions: The factors associated with gingival bleeding were age, subjective health, and tooth brushing frequency and time.

• 대한지역사회영양학회지
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• 제7권2호
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• pp.266-276
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• 2002

In this study, a computerized nutritional and health guide program for workers was developed. The dietitian at the work site could utilize periodically conducted medical examination data to develop an effective health care counseling model based on the developed Nutritional and Health Guide Program. A personal computer (Pentium II PC MMX-150, 32MB RAM, 2.95 GB HDD) with Microsoft Visual Basic 6.0 Enterprise Edition and Microsoft Access 97 installed, was used. The Nutritional and Health Guide Program consisted of seven main menus and 43 sub-menus. Included in the main menu were Basic Information, Periodic Health Check-ups, Visitors' Consultations, Nutritional/Health Tips, Nutritional Education according to Diseases, Help and Exit. In the Periodic Health Check-up menu, dieticians could input the health examination data of employees and touch for the recommended treatments for diseases such as obesity, diabetes, high cholesterol, hypertension and hepatitis. The Visitors'Consultation menu has been designed to compile health information about the employees who sought consultations. The Nutritional/Health Tips menu was designed to provide 14 kinds of programmed nutritional educational media and information. In the Nutritional Education According to Diseases menu, the dietitian could judge the subject's willingness to obtain treatment based on the Stage of Change Model. According, the content of the administered respective nutritional education was classified by stages. The Help menu, provide a chart of the method and procedure used as nutritional guidelines, by which the results of the health examination were classified as people in good health and those requiring special medical attention. The results of the evaluation of this program showed highly positive rates for usefulness (4.09), convenience (4.04), lettering size (4.02), interest (3.93), design (3.49). It also showed that 97.5% of the subjects thought that this program would be helpful for implementation of their company's nutritional educational program. Therefore, this menu could help dietitians plan, conduct, and evaluate their nutritional guidelines for employees. It is expected that The Nutritional and Health Guide Program developed in this study will play a role as a scientific and effective guide in conjunction with health examination results.

• Journal of Genetic Medicine
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• 제17권2호
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• pp.62-67
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• 2020

Purpose: Eliglustat is an oral substrate reduction therapy (SRT) approved for adults with Gaucher disease type I (GD1) who are extensive, intermediate, or poor CYP2D6 metabolizers. Here we report one-year experience of eliglustat switch therapy from long-term enzyme replacement therapy (ERT) in three adult patients with GD1. Materials and Methods: Medical history, clinical (hemoglobin concentration, platelet count, and bone mineral density) and biochemical parameters (angiotensin converting enzyme, total acid phosphatase, and lyso-gb1) of the patients were collected and evaluated by retrospective review of medical records at every 3, 6, or 12 month after switch to SRT. Results: Patient 1 was a 43-year old female diagnosed GD1 and her clinical and biochemical parameters were stabilized for more than 20 years by ERT. Due to the burden of regular hospital visit, she switched to SRT. During one-year of SRT, clinical parameters and biomarkers were maintained stable. However, after suffering acute febrile illness during SRT, she decided to re-switch to ERT due to concerns about drug interaction. Patient 2 was 41-year old male, younger brother of patient 1 and Patient 3 was 31-year old male. They switched to SRT in clinically stable condition with long-term ERT. The one-year SRT was tolerable without specific safety issue and the clinical parameters were maintained stable. Conclusion: One-year eliglustat therapy in three adult patients with GDI was generally tolerable and effective for maintaining the clinical parameters and biomarkers. However, the drug compliance, concurrent drug interactions, and long-term safety of eliglustat should be carefully monitored.

• 대한의료기공학회지
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• 제23권1호
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• pp.30-43
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• 2024

Objective : The purpose of this study is to report a case of treating alcoholic liver disease patients with jaundice and eating disorder through Korean Medicine treatment. Methods : The patient was administered with additional Gagampyeongwi-san and Sinseonbulchuidan for 30 days. For acupuncture, the colonic reducing method (大腸勝格, LI-) and spleen tonifying method (脾正格, SP+) of hand acupuncture were applied. 內關 (PC6), 公孫 (SP4), 三陰交 (SP6), and 足三里 (ST36) were basically collected, and additional 率谷 (GB8), 合谷 (LI4), and 百會 (GV20) were additionally drained and collected by body acupuncture. During the inpatient treatment period, three liver function tests were performed. Results : AST and ALT were restored to the normal range, and γ-GTP and CPK were also reduced, indicating that alcoholic hepatitis was greatly recovered. Total bilirubin and direct bilirubin were also recovered close to normal, and it was predictable that the liver excretion capacity due to hepatocellular damage was also restored, and the findings of biliary obstruction were alleviated close to normal values. When looking at the rise of eGFR along with BUN and uric acid, it seems that kidney function was recovered and improved. Conclusions : Through the combination treatment of Korean Medicine and fluid treatment, it was effective in recovering jaundice and eating disorder for alcoholic liver disease.